摘要:
Novel raw material compounds are provided that are useful for producing novel cycloalkane carboxamide derivatives having cathepsin K inhibitory action.An oxazolone derivative represented by formula (I): [wherein, R1 represents a substituted or unsubstituted alkyl group, substituted or unsubstituted alkenyl group, substituted or unsubstituted alkynyl group, substituted phenyl group, substituted or unsubstituted naphthyl group or substituted or unsubstituted heterocyclic group, and ring A represents a saturated cyclic alkylidene group having 6 to 7 carbon atoms].
摘要:
Cycloalkylcarbonylamino acid derivatives, which are raw material intermediates of a novel cycloalkane carboxamide derivative that selectively inhibits cathepsin K, and a production process thereof, are provided.A cycloalkylcarbonylamino acid derivative represented by the following general formula (I), or a pharmaceutically acceptable salt thereof: (wherein, R1 and R2 represent alkyl groups, alkenyl groups, alkynyl groups, aromatic hydrocarbon groups, heterocyclic groups or the like, and ring A represents a cyclic alkylidene group having 5, 6 or 7 carbon atoms).
摘要:
A semiconductor light emitting device comprises a metallic support plate 1; a light-reflective reflector 3 mounted on the support plate 1 and formed with a hole 3a; a semiconductor light emitting element 2 mounted on the support plate 1 within the hole 3a of the reflector 3, and a plastic encapsulant 6 for sealing an outer periphery of the reflector 3 and an upper surface 1c of the support plate 1. As the reflector 3 is electrically connected to a wiring conductor 5 or a lead wire 8 extends through a notch 3k formed in the reflector 3 to electrically connect the semiconductor light emitting element 2 and wiring conductor 5, wiring span of the lead wire 8 can be shortened to prevent deformation of the lead wire 8. Simultaneously, diameter of the reflective surface 3c in the reflector 3 is reduced and height of the reflector 3 is increased to improve directivity and axial brightness of light from the semiconductor light emitting device. Also, formation of the hole 3a effectively prevents further thermal degradation of heat-resistible plastic encapsulant 6 or other resin components.
摘要:
There is disclosed a valve assembly for a gas container capable of appropriately discharging a gas from the gas container, even if a valve of a discharge passage has a failure or the like. The valve assembly for the gas container disposed at the gas container has, as passages which allow the inside of the gas container to communicate with the outside, a filling passage which fills the gas container with the gas and a discharge passage which discharges the gas. Furthermore, the valve assembly has a filling-side valve disposed at the filling passage and configured to close this passage, a discharge-side valve disposed at the discharge passage and configured to close this passage, a communication path which connects a downstream side of the discharge-side valve to a downstream side of the filling-side valve, and a shut-off valve disposed at the communication path. When the discharge-side valve does not open due to the failure or the like, the shut-off valve is opened to allow the gas to flow through the filling passage, the communication path and the discharge passage in this order.
摘要:
An organic FET 1 comprises a substrate 2 on which a gate insulation film 41 and a reformed layer 43 are formed in this order, and a source electrode 6 and a drain electrode 8 are further arranged thereon at a predetermined distance from each other, and furthermore, an organic semiconductor layer 10 is formed on and between the electrodes 6 and 8. The reformed layer 43 fixed on the gate insulation film 41 and attached to the organic semiconductor layer 10 contains a specific compound containing the CN group or is composed of only a specific compound containing the CN group.
摘要:
A radiation-curable resin composition for shape-replication of the present invention includes a polyester resin (R) whose number average molecular weight (Mn) is 1,000 to 8,000; and a polymerizable vinyl compound (V), wherein a temperature (T4), at which a complex viscosity (η*) of components excluding any solvent at a frequency of 1 Hz is 1×104 dPa·s, is 30° C. or higher, and a temperature (T6), at which a complex viscosity (η*) at a frequency of 1 Hz is 1×106 dPa·s, is 100° C. or lower.
摘要:
A fuel cell system of the present invention includes a fuel cell stack, a fuel system for supplying a fuel gas to the fuel cell stack, and on-off valves which form a closed space not including the fuel cell stack in the fuel system. The closed space is filled with an inspection gas from the on-off valve which functions also as an inspection gas inlet port. After completion of the inspection, the inspection gas in the closed space is discharged from the on-off valve which functions also as an inspection gas outlet port.
摘要:
An electric device 1 is an organic positive thermistor in which, between two plate electrodes 2a and 2b constituting an electrode couple 2, a conductive member 41 is disposed in a state being in a close contact with the plate electrodes 2a and 2b. The conductive member 41 is formed of many piled up resin particles each having its surface formed with a conductive layer of a residual material (fullerene residual), which is the soot including fullerenes generated via, for example, an arc discharging method, from which at least a part of fullerenes is removed. Such conductive layers are joined to each other to structure the conductive path and the conduction of the electric device 1 is ensured in a normal state. When an inrush current flows, the conductive path is readily shut off by a small inflation of the resin particles due to the temperature rise.
摘要:
A feedback amplifier includes an input terminal where an input voltage is detected from an input current; an amplifier circuit which amplifies the input voltage to generate an output signal; a first output terminal from which the output signal is outputted; and a feedback circuit. The feedback circuit includes a feedback resistor connected between the input terminal and the first output terminal; and a diode which connected in parallel to the feedback resistor. The output signal is feedback-controlled in response to the product of the input current and the impedance of the feedback circuit.
摘要:
A welding robot has a gun main body, a stationary electrode tip which is immovable relative to the gun main body, and a movable electrode tip which is mounted on the gun main body and is opened and closed by a pressing source. The gun main body is movable by a driving source in a direction in which both the electrode tips lie opposite to each other. In teaching the welding robot by the movement thereof to each weld spot position of a workpiece, the movable electrode tip is moved in a closing direction relative to the gun main body by the pressing source in a state in which the gun main body is kept stationary at a predetermined position relative to the gun support bracket. The stationary electrode tip is moved in the closing direction by a relative movement of the gun main body relative to the movable electrode tip after the movable electrode tip has come into contact with the workpiece. A position at which the stationary electrode tip contacted the workpiece is detected. This position is stored as teaching data.