公开(公告)号：US08156141B1

公开(公告)日：2012-04-10

申请号：US11639038

申请日：2006-12-13

申请人： Igor Shmulevich ,  Ling Chen

发明人： Igor Shmulevich ,  Ling Chen

IPC分类号： G06F17/00

CPC分类号： G06F17/30893

摘要： Keeping incorporated web page content up to date is disclosed. A web page is associated with a stored object that has been incorporated into the web page, for example an object stored in a repository. The web page is updated automatically based at least in part on an indication that the stored object has been changed.

摘要翻译： 披露了更新的网页内容的最新版本。 网页与已经被并入网页的存储对象相关联，例如存储在存储库中的对象。 至少部分地基于存储的对象被改变的指示来自动地更新网页。

公开(公告)号：US20120053075A1

公开(公告)日：2012-03-01

申请号：US13203068

申请日：2010-01-29

申请人： Jiasen Xu ,  Zeyao Zhu ,  Ling Chen

发明人： Jiasen Xu ,  Zeyao Zhu ,  Ling Chen

IPC分类号： C40B30/04 ,  C40B40/06

CPC分类号： C12Q1/6886 ,  C12Q1/6883 ,  C12Q2600/156

摘要： Probes, liquid chips and method for detecting BRAF exon 15 mutations are disclosed. The liquid chip for detecting BRAF exon 15 mutations comprises: microspheres coupled with amino-substituted wild-type probes specific for exon 15, and microspheres coupled with amino-substituted mutant-type probes specific for exon 15; primers for amplifying target sequences enriched for mutant alleles of BRAF exons 15 and biotin-labeled at the terminal. The method of this invention is rapid and accurate in detection, and easy in operation, whereby the detection efficiency is greatly improved.

摘要翻译： 公开了探针，液芯和检测BRAF外显子15突变的方法。 用于检测BRAF外显子15突变的液体芯片包括：与特异于外显子15的氨基取代的野生型探针偶联的微球体和与特异于外显子15的氨基取代的突变型探针偶联的微球体; 用于扩增富集BRAF外显子15的突变等位基因的靶序列并在末端进行生物素标记的引物。 本发明的方法检测快速准确，操作方便，检测效率大大提高。

公开(公告)号：US08092796B2

公开(公告)日：2012-01-10

申请号：US12631598

申请日：2009-12-04

申请人： E-Chiang Lee ,  Gregory M. Landes ,  Kyu Chung ,  Ling Chen ,  Urvi Desai ,  David Reed Powell ,  Seokjoo Hong

发明人： E-Chiang Lee ,  Gregory M. Landes ,  Kyu Chung ,  Ling Chen ,  Urvi Desai ,  David Reed Powell ,  Seokjoo Hong

IPC分类号： C07K16/18 ,  A61K39/395

CPC分类号： C07K16/22 ,  A61K2039/505 ,  C07K14/515 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/56 ,  C07K2317/76 ,  C07K2317/92

摘要： Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.

摘要翻译： 提供特异性结合ANGPTL4的单克隆抗体。 提供中和至少一种ANGPTL4活性的单克隆抗体。 提供了使用中和单克隆抗体治疗脂质代谢紊乱的方法。

公开(公告)号：US20110245537A1

公开(公告)日：2011-10-06

申请号：US13134607

申请日：2011-06-09

申请人： Xueliang Yuan ,  Guoqing Mei ,  Duqing Qing ,  Weiwei Zhang ,  Ling Chen

发明人： Xueliang Yuan ,  Guoqing Mei ,  Duqing Qing ,  Weiwei Zhang ,  Ling Chen

IPC分类号： C07C227/14

CPC分类号： C07C227/16 ,  C07C229/22

摘要： L-carnitine calcium fumarate and its preparation and applications are disclosed in the present invention. Having good water solubility as well as better and stronger nutritious and treating functions than the corresponding inner salts, the L-carnitine calcium fumarate as proposed having the advantages of being non-hygroscopic, stable in chemical property, and suitable for oral administration. A preparing method is as follow: fumaric acid is suspended in water and calcium base is added. The resulting mixture is heated up to 70˜90° C. and kept under stirring for 2˜8 hours, and then concentrated under reduced pressure. The resulting dried substance is added into ethanol, and the mixture is vigorously stirred. The inner salt of L-carnitine is added, and the mixture is reacted for 1˜6 hours at 60˜70° C. and then cooled for 2˜8 hours. L-carnitine calcium fumarate is obtained by filtration.

摘要翻译： L-肉碱富马酸钙及其制备和应用在本发明中公开。 具有良好的水溶性以及比相应的内盐更好和更强的营养和处理功能，所提出的L-肉碱富马酸钙具有非吸湿性，化学性质稳定并且适合于口服给药的优点。 制备方法如下：将富马酸悬浮于水中，加入钙碱。 将所得混合物加热至70〜90℃，并保持搅拌2〜8小时，然后减压浓缩。 将所得干物质加入到乙醇中，并将混合物剧烈搅拌。 加入左旋肉碱的内盐，混合物在60〜70℃下反应1〜6小时，然后冷却2〜8小时。 通过过滤获得L-肉碱富马酸钙。

公开(公告)号：US20110233047A1

公开(公告)日：2011-09-29

申请号：US13119672

申请日：2009-09-16

申请人： Rongsheng Ruan ,  Shaoboo Deng ,  Le Zhiping ,  Yanling Cheng ,  Xiangyang Lin ,  Ling Chen

发明人： Rongsheng Ruan ,  Shaoboo Deng ,  Le Zhiping ,  Yanling Cheng ,  Xiangyang Lin ,  Ling Chen

IPC分类号： B01J19/08 ,  C01C1/02 ,  C01B3/02

CPC分类号： C01C1/0494 ,  C01B3/042 ,  Y02E60/364

摘要： The disclosure herein describes a method for producing ammonia by introducing N2, CO and water into a non-thermal plasma in the presence of a catalyst, the catalyst being effective to promote the disassociation of N2, CO and water to form reactants that in turn react to produce NH3 and CH4.This disclosure also describes producing a reactive hydrogen ion or free radical by the method comprising passing water through a non-thermal plasma in the presence of a catalyst, the catalyst being effective to promote the dissociation of water.

摘要翻译： 本文的公开内容描述了一种通过在催化剂存在下将N 2，CO和水引入非热等离子体中来生产氨的方法，所述催化剂有效促进N 2，CO和水的分离，形成反应物 以产生NH 3和CH 4。 本公开还描述了通过包括在催化剂存在下使水通过非热等离子体的方法制备反应性氢离子或自由基，该催化剂有效促进水的解离。

公开(公告)号：US07780788B2

公开(公告)日：2010-08-24

申请号：US11077753

申请日：2005-03-11

申请人： Ling Chen ,  Vincent Ku ,  Dien-Yeh Wu ,  Hua Chung ,  Alan Ouye ,  Norman Nakashima

发明人： Ling Chen ,  Vincent Ku ,  Dien-Yeh Wu ,  Hua Chung ,  Alan Ouye ,  Norman Nakashima

IPC分类号： C23C16/00 ,  H01L21/306

CPC分类号： H01L21/28562 ,  C23C16/34 ,  C23C16/4411 ,  C23C16/4412 ,  C23C16/45504 ,  C23C16/45508 ,  C23C16/45512 ,  C23C16/45525 ,  C23C16/45544 ,  C23C16/45563 ,  C23C16/45582 ,  H01L21/76843 ,  H01L21/76846 ,  H01L21/76871

摘要： Apparatus and method for forming thin layers on a substrate are provided. A processing chamber has a gas delivery assembly that comprises a lid with a cap portion and a covering member that together define an expanding channel at a central portion of the lid, the covering member having a tapered bottom surface extending from the expanding channel to a peripheral portion of the covering member. Gas conduits are coupled to the expanding channel and positioned at an angle from a center of the expanding channel to form a circular gas flow through the expanding channel, The bottom surface of the chamber lid is shaped and sized to substantially cover the substrate receiving surface. One or more valves are coupled to the passageway, and one or more gas sources are coupled to each valve. A choke is disposed on the chamber lid adjacent a perimeter of the tapered bottom surface.

摘要翻译： 提供了在基板上形成薄层的装置和方法。 处理室具有气体输送组件，其包括具有盖部分的盖和覆盖部件，所述盖部在盖的中心部分处共同限定出扩张通道，所述覆盖部件具有从扩张通道延伸到外围的锥形底面 覆盖部件的一部分。 气体管道连接到膨胀通道并且与膨胀通道的中心成角度地定位，以形成通过膨胀通道的圆形气体流动。腔室盖的底表面的形状和尺寸基本上覆盖基底接收表面。 一个或多个阀联接到通道，并且一个或多个气体源联接到每个阀。 扼流圈设置在邻近锥形底面的周边的腔室盖上。

公开(公告)号：US20100055167A1

公开(公告)日：2010-03-04

申请号：US12546969

申请日：2009-08-25

申请人： Alex Zhang ,  Yunqian Guan ,  Ling Chen

发明人： Alex Zhang ,  Yunqian Guan ,  Ling Chen

IPC分类号： A61K9/127 ,  A61K48/00 ,  A61K39/395 ,  A61P35/00 ,  A61K9/14

CPC分类号： A61K9/5115 ,  A61K9/0085 ,  A61K35/28 ,  A61K45/06 ,  C12N5/0663 ,  A61K2300/00

摘要： The present disclosure provides a modified stem cell comprising a stem cell and at least one controlled-release vehicle, wherein the at least one controlled-release vehicle includes at least one anti-neoplastic agent and at least one targeting moiety, and wherein the modified stem cell is characterized by an ability to target one or more glioma cells. The disclosure also provides pharmaceutical compositions and methods of treating a glioma by administering a therapeutically effective amount of the modified stem cells.

摘要翻译： 本公开提供了包含干细胞和至少一种控释载体的修饰的干细胞，其中所述至少一种控释载体包含至少一种抗肿瘤剂和至少一种靶向部分，并且其中所述修饰的茎 细胞的特征在于靶向一个或多个胶质瘤细胞的能力。 本公开还提供了通过施用治疗有效量的修饰的干细胞来治疗胶质瘤的药物组合物和方法。

公开(公告)号：US20100027519A1

公开(公告)日：2010-02-04

申请号：US12442312

申请日：2007-09-19

申请人： Ling Chen

发明人： Ling Chen

IPC分类号： H04W84/12

CPC分类号： H04W24/00 ,  H04W8/26 ,  H04W36/06 ,  H04W48/08 ,  H04W84/12 ,  H04W88/08

摘要： The embodiments disclose a method for scanning in a radio communication system, in particular in a WLAN (Wireless Local Area Network), including transmitting by a MS on all channels a probe message containing the IP address of the original AP of the MS and an MAC address of the MS; switching to the original channel; transmitting a response inquiry message to the original AP; and receiving a probe response message within a predetermined period, wherein, if the AP of the probe message received on the channel is not the original AP, then the AP transmits the probe response message containing the MAC address to the original AP according to the IP address; and the original AP buffers the probe response message received, and transmits the probe response message to the MS according to the MAC address after the response inquiry message sent by the MS has been received. The embodiments further disclose a scanning system in a WLAN. By using the method and system, not only the time delay during the scanning is reduced, but also the network security is improved and the difficulty for realization is decreased.

摘要翻译： 实施方式公开了一种用于在无线电通信系统中扫描的方法，特别是在无线局域网（Wireless Local Area Network，无线局域网））中，包括由MS在所有信道上发送包含MS的原始AP的IP地址的探测消息和MAC MS地址; 切换到原来的频道; 向原始AP发送响应查询消息; 并且在预定时段内接收探测响应消息，其中如果在所述信​​道上接收到的所述探测消息的所述AP不是所述原始AP，则所述AP根据所述IP向所述原始AP发送包含所述MAC地址的所述探测响应消息 地址; 并且原始AP缓冲所接收到的探测响应消息，并且在已经接收到MS发送的响应查询消息之后，根据MAC地址向MS发送探测响应消息。 实施例进一步公开了WLAN中的扫描系统。 通过使用该方法和系统，不仅可以减少扫描时间延迟，而且可以提高网络安全性，降低实现难度。

公开(公告)号：US07604771B2

公开(公告)日：2009-10-20

申请号：US11418957

申请日：2006-05-05

申请人： Sun-Ju Song ,  Tae H. Lee ,  Ling Chen ,  Stephen E. Dorris ,  Uthamalingam Balachandran

发明人： Sun-Ju Song ,  Tae H. Lee ,  Ling Chen ,  Stephen E. Dorris ,  Uthamalingam Balachandran

IPC分类号： B28B3/00 ,  B01D53/22

CPC分类号： C04B38/0635 ,  B01D53/228 ,  B01D67/0041 ,  B01D67/0058 ,  B01D71/024 ,  B01D2256/16 ,  B01D2323/18 ,  B22F3/1134 ,  B22F2998/00 ,  B22F2998/10 ,  C01B3/505 ,  C01B2203/0465 ,  C04B35/50 ,  C04B38/08 ,  C04B2111/00267 ,  C04B2111/00413 ,  C04B2111/00801 ,  C04B2235/3215 ,  C04B2235/3225 ,  C04B2235/3229 ,  C04B2235/3279 ,  C22C2202/04 ,  Y10T428/249981 ,  C04B35/01 ,  C04B35/48 ,  C04B35/505 ,  B22F2207/01 ,  B22F3/1017 ,  B22F2201/013

摘要： A thermal method of making a hydrogen permeable composition is disclosed. A mixture of metal oxide powder and ceramic oxide powder and optionally a pore former is formed and pressed to form an article. The article is dried at elevated temperatures and then sintered in a reducing atmosphere to provide a dense hydrogen permeable portion near the surface of the sintered mixture. The dense hydrogen permeable portion has a higher initial concentration of metal than the remainder of the sintered mixture and is present in the range of from about 20 to about 80 percent by volume of the dense hydrogen permeable portion.

摘要翻译： 公开了制造氢可渗透组合物的热法。 形成金属氧化物粉末和陶瓷氧化物粉末和任选的成孔剂的混合物并压制以形成制品。 将制品在升高的温度下干燥，然后在还原气氛中烧结，以在烧结混合物的表面附近提供致密的氢气渗透部分。 致密的氢气渗透部分具有比烧结混合物的其余部分更高的金属初始浓度，并且其存在的浓氢可渗透部分的约20至约80体积％。

公开(公告)号：US20090151633A1

公开(公告)日：2009-06-18

申请号：US12371138

申请日：2009-02-13

申请人： Ling Chen ,  Vincent W. Ku ,  Hua Chung ,  Christophe Marcadal ,  Seshadri Ganguli ,  Jenny Lin ,  Dien-Yeh Wu ,  Alan Ouye ,  Mei Chang

发明人： Ling Chen ,  Vincent W. Ku ,  Hua Chung ,  Christophe Marcadal ,  Seshadri Ganguli ,  Jenny Lin ,  Dien-Yeh Wu ,  Alan Ouye ,  Mei Chang

IPC分类号： C23C16/54

CPC分类号： C23C16/45544 ,  C23C16/18 ,  C23C16/34 ,  C23C16/4402 ,  C23C16/4481 ,  C23C16/4482 ,  C23C16/4487 ,  Y10T117/10 ,  Y10T117/1004 ,  Y10T117/1008

摘要： Embodiments described herein are directed to an apparatus for generating a precursor for a semiconductor processing system. In one embodiment, an apparatus for generating a precursor gas during a vapor deposition process is described. The apparatus includes a canister containing an interior volume between a lid and a bottom, a gaseous inlet and a gaseous outlet disposed on the lid, a plurality of silos coupled to the bottom and extending from a lower region to an upper region of the interior volume, and a tantalum precursor having a chlorine concentration of about 5 ppm or less contained within the lower region of the canister.

摘要翻译： 本文描述的实施例涉及用于产生半导体处理系统的前体的装置。 在一个实施例中，描述了在气相沉积工艺期间产生前体气体的装置。 该装置包括容纳盖和底部之间的内部容积的容器，设置在盖上的气体入口和气体出口，与底部相连并从内部容积的下部区域延伸到上部区域的多个筒仓 ，以及包含在罐的下部区域内的氯浓度为约5ppm以下的钽前体。