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    STERILE SAMPLE INJECTOR AND METHOD
    113.
    发明申请
    STERILE SAMPLE INJECTOR AND METHOD 审中-公开

    公开(公告)号：US20180164190A1

    公开(公告)日：2018-06-14

    申请号：US15853809

    申请日：2017-12-24

    Applicant: MOR RESEARCH APPLICATIONS LTD.

    Inventor： Amir HADAYER ,  Noa Hana HADAYER ,  Arie Leonid MARCOVICH

    IPC: G01N1/08 ,  G01N35/10 ,  C12M1/26 ,  G01N1/14

    CPC classification number: G01N1/08 ,  C12M33/04 ,  G01N1/14 ,  G01N35/1079 ,  G01N2001/1427

    Abstract: A sterile injector comprises a body having a cavity, a hollow needle positionable at a distal end of the injector, a probe holder receivable within the needle, a probe connected to a distal end of the holder, and a driving element axially displaceable within the cavity, for causing relative motion between the probe and the needle upon displacement of the driving element. A sample is injected into a sealed container by displacing the driving element to a first position causing the probe to extend from the needle, applying the extended probe with a sample, displacing the driving element to a second position causing the sample laden probe to be retracted within the needle, piercing a seal of a sealed container with the needle, and displacing the driving element to a third position distally spaced from the first position, after which the probe is injected into the container interior.

    Device for placement in the tricuspid annulus
    116.
    发明授权
    Device for placement in the tricuspid annulus 有权
    置于三尖瓣环的装置

    公开(公告)号：US09445893B2

    公开(公告)日：2016-09-20

    申请号：US14359646

    申请日：2012-11-21

    Applicant: Mor Research Applications Ltd.

    Inventor： Mordehay Vaturi

    IPC: A61F2/24

    CPC classification number: A61F2/24 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2454 ,  A61F2/246 ,  A61F2/2463

    Abstract: A device (200) for implantation in or near an annulus of a tricuspid valve comprising at least one blood flow control element (202) adapted to capture a volume of blood therein. Optionally or alternatively, the blood flow control element is adapted to allow at least some volume of blood (406) to regurgitate through the annulus during at least some part of systole. Optionally or alternatively, the device comprises a relatively rigid annulus with an arc length of less than 300 degrees. Optionally or alternatively, the relatively rigid annulus comprises a plurality of tissue fixation elements positioned along no more than 300 degrees of a circumference of the annulus, for example to avoid damaging conduction pathways between an atria and a chamber.

    Abstract translation: 一种用于植入三尖瓣环或其附近的装置（200），包括适于捕获一定体积的血液的至少一个血流控制元件（202）。 任选地或替代地，血流控制元件适于允许至少一定体积的血液（406）在至少一部分收缩期间通过环带回流。 可选地或替代地，该装置包括弧形长度小于300度的相对刚性的环形空间。 可选地或替代地，相对刚性的环形空间包括多个组织固定元件，所述多个组织固定元件沿环形圆周不超过300度定位，例如以避免损坏心房和腔室之间的传导路径。

    COMPOSITIONS AND METHODS FOR TREATMENT OF RETINAL DEGENERATIVE DISEASES
    117.
    发明申请
    COMPOSITIONS AND METHODS FOR TREATMENT OF RETINAL DEGENERATIVE DISEASES 有权
    治疗退行性疾病的组合物和方法

    公开(公告)号：US20160114006A1

    公开(公告)日：2016-04-28

    申请号：US14894347

    申请日：2014-05-29

    Applicant: MOR RESEARCH APPLICATIONS LTD.

    Inventor： Ayala POLLACK ,  Zeev DVASHI

    IPC: A61K38/45 ,  A61K31/40

    CPC classification number: A61K38/45 ,  A61K31/40 ,  A61K38/1709 ,  C12Y207/11025

    Abstract: This disclosure relates to compositions for use in treatment of a retinal degenerative disease, such as age related macular degeneration. The described compositions include agents for activating p38 and/or JNK signaling through the activation of TAK1 in the retinal pigment epithelium of a subject diagnosed with the disease. Methods of treatment of a retinal degenerative disease using the described compositions are also provided.

    Abstract translation: 本公开涉及用于治疗视网膜退化性疾病如老年性黄斑变性的组合物。 所描述的组合物包括通过在诊断患有该疾病的受试者的视网膜色素上皮中激活TAK1来激活p38和/或JNK信号传导的药剂。 还提供了使用所述组合物治疗视网膜退行性疾病的方法。

    APPARATUS AND METHOD FOR DIAGNOSING SLEEP QUALITY
    118.
    发明申请
    APPARATUS AND METHOD FOR DIAGNOSING SLEEP QUALITY 审中-公开
    用于诊断睡眠质量的装置和方法

    公开(公告)号：US20150119741A1

    公开(公告)日：2015-04-30

    申请号：US14404621

    申请日：2013-05-30

    Applicant: BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY ,  MOR RESEARCH APPLICATIONS LTD

    Inventor： Yaniv Zigel ,  Eliran Dafna ,  Ariel Tarasiuk

    IPC: A61B5/00 ,  A61B7/00 ,  A61B7/04 ,  A61B5/08

    CPC classification number: A61B5/4812 ,  A61B5/0816 ,  A61B5/0823 ,  A61B5/0826 ,  A61B5/4809 ,  A61B5/4815 ,  A61B5/4818 ,  A61B5/6898 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/7278 ,  A61B7/003 ,  A61B7/04

    Abstract: A method of distinguishing sleep period states that a person experiences during a sleep period, the method comprising: using a non-contact microphone to acquire a sleep sound signal representing sounds made by a person during sleep; segmenting the sleep sound signals into epochs; generating a sleep sound feature vector for each epoch; providing a first model that gives a probability that a given sleep period state experienced by the person in a given epoch exhibits a given sleep sound feature vector; providing a second model that gives a probability that a first sleep period state associated with a first epoch transitions to a second sleep period state associated with a subsequent second epoch; and processing the feature vectors using the first and second models to determine a sleep period state of the person from a plurality of possible sleep period states for each of the epochs.

    Abstract translation: 一种区分睡眠期间人体经历的睡眠周期状态的方法，所述方法包括：使用非接触麦克风来获取表示睡眠期间人的声音的睡眠声音信号; 将睡眠声音信号分解成时代; 为每个时期产生睡眠声音特征向量; 提供第一模型，其给出给定时代中的人经历的给定睡眠时段状态呈现给定睡眠声音特征向量的概率; 提供第二模型，其给出与第一时期相关联的第一睡眠周期状态转换到与随后的第二时期相关联的第二睡眠周期状态的概率; 以及使用所述第一模型和所述第二模型处理所述特征向量，以针对每个所述时期从多个可能的睡眠周期状态确定所述人的睡眠周期状态。

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