公开(公告)号：US08522348B2

公开(公告)日：2013-08-27

申请号：US12846541

申请日：2010-07-29

Applicant: Yan Chen ,  Zhichun Li ,  Gao Xia ,  Bin Liu

Inventor： Yan Chen ,  Zhichun Li ,  Gao Xia ,  Bin Liu

IPC: G06F11/00

CPC classification number: H04L63/1416 ,  H04L63/1433 ,  H04L69/22

Abstract: Systems, methods, and apparatus are provided for vulnerability signature based Network Intrusion Detection and/or Prevention which achieves high throughput comparable to that of the state-of-the-art regex-based systems while offering improved accuracy. A candidate selection algorithm efficiently matches thousands of vulnerability signatures simultaneously using a small amount of memory. A parsing transition state machine achieves fast protocol parsing. Certain examples provide a computer-implemented method for network intrusion detection. The method includes capturing a data message and invoking a protocol parser to parse the data message. The method also includes matching the parsed data message against a plurality of vulnerability signatures in parallel using a candidate selection algorithm and detecting an unwanted network intrusion based on an outcome of the matching.

Abstract translation: 提供了基于漏洞签名的网络入侵检测和/或预防的系统，方法和装置，其实现了与现有技术的基于正则表达式的系统相当的高吞吐量，同时提供了更高的精度。 候选者选择算法使用少量内存同时有效地匹配数千个漏洞签名。 解析过渡状态机实现快速协议解析。 某些示例提供用于网络入侵检测的计算机实现的方法。 该方法包括捕获数据消息并调用协议解析器来解析数据消息。 该方法还包括使用候选选择算法并行地解析解析的数据消息与多个脆弱性签名并且基于匹配的结果来检测不需要的网络入侵。

公开(公告)号：US08507290B2

公开(公告)日：2013-08-13

申请号：US13498985

申请日：2010-09-28

Applicant: Bin Liu ,  Kanyi Pu

Inventor： Bin Liu ,  Kanyi Pu

IPC: G01N21/64 ,  G01N33/50 ,  C07F7/21

CPC classification number: C07F7/21 ,  B82Y15/00 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1014 ,  C09K2211/1051 ,  G01N33/54386 ,  G01N33/582 ,  G01N33/588

Abstract: The present invention generally relates to water-soluble, highly fluorescent polyhedral oligomeric silsesquioxane (POSS) compounds useful for sensing and bioimaging applications.

Abstract translation: 本发明通常涉及可用于感测和生物成像应用的水溶性，高度荧光的多面体低聚倍半硅氧烷（POSS）化合物。

公开(公告)号：US20130182259A1

公开(公告)日：2013-07-18

申请号：US13513052

申请日：2010-12-01

Applicant: Mark Brezinski ,  Bin Liu ,  Ehsan Azimi

Inventor： Mark Brezinski ,  Bin Liu ,  Ehsan Azimi

IPC: G01B9/02

CPC classification number: G01B9/02091 ,  A61B5/0066 ,  A61B5/7257 ,  G01B9/02044 ,  G01B9/02074 ,  G01N21/4795 ,  G01N2021/1787

Abstract: Systems and methods for enhancing spectral domain optical coherence tomography (OCT] are provided. In particular, a system and method for calibration of spectral interference signals using an acquired calibration signal are provided. The calibration signal may be logarithmically amplified to further improve the accuracy of the calibration. From the calibration signal, a series of more accurate calibration data are calculated. An acquired spectral interference signal is calibrated using these calibration data. Moreover, systems that include logarithmic amplification of the spectral interference signal and variable band-pass filtering of the spectral interference signal are provided. Such systems increase the dynamic range and visualization capabilities relative to conventional spectral domain OCT systems.

Abstract translation: 提供了增强频域光学相干断层扫描（OCT）的系统和方法，特别提供了一种使用采集的校准信号校准光谱干扰信号的系统和方法，校准信号可以对数放大，以进一步提高 校准，从校准信号中计算出一系列更准确的校准数据，采用这些校准数据对采集到的光谱干涉信号进行校准，而且包括频谱干扰信号的对数放大和可变带通滤波的系统 提供了光谱干扰信号，相对于常规光谱域OCT系统，这种系统增加了动态范围和可视化能力。

公开(公告)号：US20130109029A1

公开(公告)日：2013-05-02

申请号：US13806447

申请日：2011-06-29

Applicant: Bin Liu ,  Kanyi Pu ,  Kai Li ,  Liping Cai ,  Yanyan Wang ,  Dan Ding

Inventor： Bin Liu ,  Kanyi Pu ,  Kai Li ,  Liping Cai ,  Yanyan Wang ,  Dan Ding

IPC: C07K17/02

CPC classification number: C07K17/02 ,  B82Y15/00 ,  C07D285/10 ,  C09K11/06 ,  C09K2211/1416 ,  G01N33/582 ,  G01N33/588

Abstract: The present invention relates to conjugated polyelectrolyte (CPE) or oligoelectrolyte (COE) compounds represented by general structural formulae (I)-(IV), or a salt thereof and methods of using these compounds to detect targets in samples. In particular, the methods include: (1) exposing a sample to a compound of structural formula (I), (II) or (IV) or a salt thereof, allowing the compound to bind to a target and detecting a signal produced by the compound; (2) functionalizing a solid support with a ligand, incubating the sample with a charged CPE or COE and detecting the fluorescence of the solid support and thereby detecting the target or (3) functionalizing a surface of a solid support with a charged ligand, thereby creating a charge on the surface of the solid support; incubating the ligand-functionalized solid support with a sample, whereupon binding of the target, the charge on the surface of the solid support switches; incubating the sample with CPE or COE that has a complementary charge to the charge of the target-bound surface; and detecting the fluorescence of the solid support and thereby detecting the target. The compounds of the present invention possess high photoluminescence quantum yields in biological media, low cytotoxicity, and excellent environmental stability and photostability and can be used in biosensor and bioimaging applications.

Abstract translation: 本发明涉及由通式（I） - （IV）表示的共轭聚电解质（CPE）或低聚电解质（COE）化合物或其盐，以及使用这些化合物检测样品中靶标的方法。 特别地，所述方法包括：（1）将样品暴露于结构式（I），（II）或（IV）的化合物或其盐，使化合物与靶标结合并检测由 复合; （2）用配体官能化固体支持物，将样品与带电荷的CPE或COE孵育并检测固体支持物的荧光，从而检测靶，或（3）用带电的配体使固体支持物的表面官能化，从而 在固体支撑体的表面上产生电荷; 将配体官能化的固体支持物与样品一起孵育，随后靶标结合，固体支持开关表面上的电荷; 将样品与具有补充电荷的CPE或COE孵育到靶结合表面的电荷; 并检测固体支持物的荧光，从而检测目标物。 本发明的化合物在生物培养基中具有高的光致发光量子产率，低的细胞毒性和优异的环境稳定性和光稳定性，并可用于生物传感器和生物成像应用。

公开(公告)号：US08338532B2

公开(公告)日：2012-12-25

申请号：US13038378

申请日：2011-03-01

Applicant: Guillermo C. Bazan ,  Bin Liu

Inventor： Guillermo C. Bazan ,  Bin Liu

IPC: C08G63/91 ,  C08G63/00 ,  C12Q1/68

CPC classification number: C08G61/02 ,  C08G61/122 ,  C08G61/123 ,  C12Q1/6818 ,  C12Q1/6837 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6439 ,  C12Q2563/131 ,  C12Q2537/119 ,  C12Q2525/107

Abstract: The invention further relates to multichromophores, which may be conjugated polymers, and methods, articles and compositions employing them as described herein. In some aspects, the invention relates to methods, articles and compositions for the detection and analysis of biomolecules in a sample. Provided assays include those determining the presence of a target biomolecule in a sample or its relative amount, or the assays may be quantitative or semi-quantitative. The methods can be performed on a substrate. The methods can be performed in an array format on a substrate, which can be a sensor. In some embodiments, detection assays are provided employing sensor biomolecules that do not comprise a fluorophore that can exchange energy with the cationic multichromophore. In some aspects biological assays are provided in which energy is transferred between one or more of the multichromophore, a label on the target biomolecule, a label on the sensor biomolecule, and/or a fluorescent dye specific for a polynucleotide, in all permutations. The multichromophore may interact at least in part electrostatically with the sensor and/or the target, and an increase in energy transfer with the polymer may occur upon binding of the sensor and the target. Other variations of the inventions are described further herein.

Abstract translation: 本发明还涉及可以是共轭聚合物的多色素，以及如本文所述使用它们的方法，制品和组合物。 在一些方面，本发明涉及用于检测和分析样品中生物分子的方法，制品和组合物。 提供的测定包括确定样品中靶生物分子的存在或其相对量的那些，或者测定可以是定量或半定量的。 该方法可以在衬底上进行。 这些方法可以以阵列格式在基底上进行，其可以是传感器。 在一些实施方案中，使用不包含能够与阳离子多重色素交换能量的荧光团的传感器生物分子来提供检测测定。 在一些方面，提供生物测定，其中在所有置换中，能量在一个或多个多色素，目标生物分子上的标记，传感器生物分子上的标记和/或多核苷酸特异的荧光染料之间转移。 多重色淀可以至少部分地与传感器和/或靶相互作用，并且当传感器和目标物结合时，聚合物的能量传递的增加可能发生。 本文进一步描述了本发明的其它变型。

公开(公告)号：US08265748B2

公开(公告)日：2012-09-11

申请号：US12350749

申请日：2009-01-08

Applicant: Bin Liu ,  Hu Luo

Inventor： Bin Liu ,  Hu Luo

IPC: A61N1/34

CPC classification number: A61N1/046 ,  A61N1/0472 ,  A61N1/0492 ,  A61N1/3925 ,  A61N1/3993

Abstract: A defibrillator includes a defibrillator mainframe and a defibrillating electrode. The defibrillator mainframe includes a main control unit and a master device electrically connected to the main control unit. The defibrillating electrode comprises a slave device supporting a bus protocol, the master device and slave device being interconnected through a bus.

Abstract translation: 除颤器包括除颤器主机和去纤颤电极。 除颤器主机包括主控制单元和与主控制单元电连接的主设备。 除颤电极包括支持总线协议的从设备，主设备和从设备通过总线互连。

公开(公告)号：US08208856B2

公开(公告)日：2012-06-26

申请号：US12686623

申请日：2010-01-13

Applicant: Mark Hahm ,  Wei Luo ,  Thirunathan Sutharsan ,  Andrew du Preez ,  Bin Liu ,  Jun Wu ,  Severine Catreux-Erceg ,  Shuangquan Wang

Inventor： Mark Hahm ,  Wei Luo ,  Thirunathan Sutharsan ,  Andrew du Preez ,  Bin Liu ,  Jun Wu ,  Severine Catreux-Erceg ,  Shuangquan Wang

IPC: H04B1/00

CPC classification number: H04B1/71075 ,  H04B1/7115 ,  H04B1/712 ,  H04B2201/70702

Abstract: Aspects of a method and system for a programmable interference suppression module may include receiving a communication signal comprising one or more desired signal, and one or more undesired signals. The communication signal may be utilized to generate estimated channel state information. The estimated channel state information may be formatted for use in interference suppression. A reduced interference signal may be generated from a delayed version of said communications signal and the estimated channel state information, wherein the one or more undesired signals may be attenuated. The reduced interference signal may be formatted for post-processing. The desired signals may comprise WCDMA and/or HSDPA signals, and the undesired signals may be inter-cell and/or intra-cell interference. Further processing may comprise HSDPA processing and/or RAKE finger processing. The communication signal may be a Universal Mobile Telecommunication System (UMTS) compliant signal.

Abstract translation: 用于可编程干扰抑制模块的方法和系统的方面可以包括接收包括一个或多个期望信号的通信信号以及一个或多个不需要的信号。 通信信号可用于产生估计的信道状态信息。 估计的信道状态信息可以被格式化以用于干扰抑制。 可以从所述通信信号的延迟版本和所估计的信道状态信息产生减小的干扰信号，其中所述一个或多个不需要的信号可以被衰减。 减小的干扰信号可以被格式化用于后处理。 期望的信号可以包括WCDMA和/或HSDPA信号，并且不期望的信号可以是小区间和/或小区内干扰。 进一步的处理可以包括HSDPA处理和/或RAKE手指处理。 通信信号可以是符合通用移动通信系统（UMTS）的信号。

公开(公告)号：US08185155B2

公开(公告)日：2012-05-22

申请号：US13026234

申请日：2011-02-12

Applicant: Eric Chang ,  David Dehghan ,  Stanley Sun ,  Bin Liu

Inventor： Eric Chang ,  David Dehghan ,  Stanley Sun ,  Bin Liu

IPC: H04B1/38

CPC classification number: H04M1/72527

Abstract: A universal smart interface and peripheral management system for portable devices such as mobile phones. The smart system includes a connector interface that connects peripherals to a phone and/or personal digital assistant (PDA), through the smart system. The smart system includes a cradle for receiving a cell phone and interfacing the phone to external systems such as peripherals, networks and other systems through a USB hub and other suitable connector interfaces. The peripheral devices to which the smart system can interface include, but are not limited to, large displays (e.g., television), external monitors, input devices such as mice and keyboards, external storage devices, and networks (wired and/or wireless). The smart system also facilitates connectivity to large display systems such as TVs, computer displays and monitors.

Abstract translation: 通用智能接口和便携式设备（如手机）的外设管理系统。 智能系统包括通过智能系统将外围设备连接到电话和/或个人数字助理（PDA）的连接器接口。 该智能系统包括用于接收蜂窝电话并通过USB集线器和其他合适的连接器接口将电话与诸如外围设备，网络和其他系统的外部系统接口的支架。 智能系统可以接口的外围设备包括但不限于大型显示​​器（例如电视机），外部监视器，诸如鼠标和键盘的输入设备，外部存储设备和网络（有线和/或无线） 。 智能系统还有助于连接大型显示系统，如电视机，电脑显示器和显示器。

公开(公告)号：US08110673B2

公开(公告)日：2012-02-07

申请号：US12711233

申请日：2010-02-23

Applicant: Guillermo C. Bazan ,  Bin Liu

Inventor： Guillermo C. Bazan ,  Bin Liu

IPC: C07H21/04

CPC classification number: G01N21/6486 ,  C08G61/02 ,  C08G61/123 ,  C12Q1/6818 ,  C12Q1/6825 ,  G01N33/542 ,  G01N33/54373 ,  Y10T436/143333 ,  C12Q2565/113 ,  C12Q2563/173 ,  C12Q2565/101

Abstract: This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein.

Abstract translation: 本发明涉及可用于检测和分析样品中的聚集体的聚集传感器，以及与这种传感器相关的方法，制品和组合物。 传感器包括第一和第二光学有源单元，其中能量可以从第一光学活性单元的激发状态转移到第二光学活性单元。 第二光学活性单元以较小的量存在，但是其聚集时其相对浓度增加，从而增加其从第一光学活性单元的能量吸收。 可以以各种格式检测能量转移的这种增加，以产生用于各种聚合物的聚集感测系统，包括用于定量。 本文进一步描述了本发明的其它变型。

公开(公告)号：US20110103530A1

公开(公告)日：2011-05-05

申请号：US12611810

申请日：2009-11-03

Applicant: Wei Luo ,  Karthik Rajagopalan ,  Andrew du Preez ,  Bin Liu ,  Shuangquan Wang

Inventor： Wei Luo ,  Karthik Rajagopalan ,  Andrew du Preez ,  Bin Liu ,  Shuangquan Wang

IPC: H04B1/10

CPC classification number: H04B1/7107

Abstract: Aspects of a method and system for compensation of interference cancellation delay are provided. In this regard, a wireless communication device may receive one or more signals and may be operable to select, whether dynamically or statically, a processing path for processing the one or more received signals. The selected processing path may comprise one of an interference cancellation processing path and a pass-through processing path. A delay introduced by the pass-through processing path may be approximately equal to a processing delay introduced by the interference cancellation processing path. The one or more received signals may comprise HSDPA signals. The selection of processing path may be based on a measure of interference present in the one or more received signals.

Abstract translation: 提供了一种用于补偿干扰消除延迟的方法和系统。 在这方面，无线通信设备可以接收一个或多个信号，并且可以可操作地动态地或静态地选择用于处理一个或多个接收信号的处理路径。 所选择的处理路径可以包括干扰消除处理路径和直通处理路径之一。 由直通处理路径引入的延迟可以近似等于由干扰消除处理路径引入的处理延迟。 一个或多个接收信号可以包括HSDPA信号。 处理路径的选择可以基于存在于一个或多个接收信号中的干扰的度量。