Plasminogen activator covalently bonded to a porous body of
.beta.-tricalcium phosphate
    121.
    发明授权
    Plasminogen activator covalently bonded to a porous body of .beta.-tricalcium phosphate 失效
    共价键合到β-磷酸三钙的多孔体上的纤溶酶原激活物

    公开(公告)号:US5491082A

    公开(公告)日:1996-02-13

    申请号:US246940

    申请日:1994-05-20

    摘要: A plasminogen activator such as urokinase or tissue plasminogen activator is covalently bonded to a porous body composed of calcium phosphate to form a plasminogen activator-porous body complex. The tricalcium phosphate can be .alpha.-tricalcium phosphate, .beta.-tricalcium phosphate, hydroxyapatite, tetracalcium phosphate, octacalcium phosphate and mixtures thereof. In a preferred embodiment, .beta.-tricalcium phosphate which has excellent biocompatibility with the body or a mixture of .beta.-tricalcium phosphate and hydroxyapatite is used. Preferably, synthetic calcium phosphate is used is to avoid impurities contained by natural calcium phosphate. Covalent bonding is by crosslinking with glutaraldehyde, bismaleimides, dihalogenic aryls or diisocyanates, or by using cyanogen bromide, diazotization or periodic acid. The complex can be filled into a column to form a bioreactor. A granular complex can be intravascularly injected into the blood of a patient to provide thrombotic activity for a long period of time. In another embodiment, a complex of a predetermined shape can be implanted to provide thrombotic activity.

    摘要翻译: 纤维蛋白溶酶原激活剂如尿激酶或组织纤溶酶原激活剂共价键合到由磷酸钙组成的多孔体上以形成纤溶酶原激活剂多孔体复合体。 磷酸三钙可以是α-磷酸三钙,β-磷酸三钙,羟基磷灰石,磷酸四钙,磷酸八钙及其混合物。 在优选的实施方案中,使用与身体具有优异生物相容性的β-磷酸三钙或磷酸β-磷酸钙和羟基磷灰石的混合物。 优选地,合成磷酸钙是为了避免天然磷酸钙含有的杂质。 共价键是通过与戊二醛,双马来酰亚胺,二卤代芳基或二异氰酸酯交联,或通过使用溴化氰,重氮化或高碘酸进行交联。 复合物可以填充到柱中以形成生物反应器。 颗粒状复合物可以血管内注射到患者的血液中以长时间提供血栓形成活性。 在另一个实施方案中,可以植入预定形状的复合物以提供血栓形成活性。

    Igniter plug
    125.
    发明授权
    Igniter plug 失效
    IGNITER插头

    公开(公告)号:US5073741A

    公开(公告)日:1991-12-17

    申请号:US635730

    申请日:1990-12-28

    IPC分类号: H01T13/52 H01T13/32

    CPC分类号: H01T13/32

    摘要: An igniter plug has a tubular metallic shell and an annular ground electrode each connected in series by an interfitting, and fixed by welding. The igniter plug further has a tubular insulator placed within both the metallic shell and the ground electrode, while a center electrode is placed within the insulator to be surrounded by the ground electrode. A plurality of lock arms are provided with a front end of the metallic shell, and each top end of lock arms has a pawl which is brought into an engagement with an inner wall of a groove which is provided with an inner surface of the ground electrode when the metallic shell and the ground electrode are connected, and at the same time, the insulator is brought into an engagement with an inner side of each lock arm to deter the lock arms from being flexed inwardly when the insulator is placed.

    摘要翻译: 点火塞具有管状金属壳和环形接地电极,每个通过相互连接串联连接,并通过焊接固定。 点火器插头还具有放置在金属壳体和接地电极内的管状绝缘体,而中心电极放置在绝缘体内以被接地电极包围。 多个锁定臂设置有金属壳的前端,并且锁定臂的每个顶端具有棘爪,该棘爪与设置有接地电极的内表面的槽的内壁接合 当金属壳和接地电极连接时,同时绝缘体与每个锁定臂的内侧接合以阻止锁定臂在放置绝缘体时向内弯曲。

    Method for manufacturing removable information sheet

    公开(公告)号:US11635724B2

    公开(公告)日:2023-04-25

    申请号:US17468742

    申请日:2021-09-08

    IPC分类号: G03G15/00 G03G9/087 G03G15/20

    摘要: A method for manufacturing a removable information sheet includes: forming a toner image on a recording medium; applying an energy-ray-curable pressure-sensitive composition precursor onto the medium to form an energy-ray-curable pressure-sensitive composition precursor layer; irradiating, with an energy ray, the medium to cure the layer and form an energy-ray-curable pressure-sensitive composition; and attaching faces with the composition and pressure-bonding the faces. A region size of a toner-image flat part is 200 μm or less in the image, which is determined by a measurement method including: defining a site at a depth of 2 μm or more from a surface of a solid part of the image as a recess; defining a site other than the recess as the flat part; acquiring and binarizing a micrograph of the solid part; drawing circles out of contact with the recess; and defining a largest circle diameter as the size of the flat part.

    Electric motor drive device
    129.
    发明授权
    Electric motor drive device 有权
    电动机驱动装置

    公开(公告)号:US09325264B2

    公开(公告)日:2016-04-26

    申请号:US14391578

    申请日:2012-04-12

    IPC分类号: H02P6/18 H02P21/14

    CPC分类号: H02P6/187 H02P21/18

    摘要: An electric motor drive device 1000 includes: an inverter 3 that drives a motor 4, a voltage division circuit 2 that serves as a neutral point potential detection unit that detects a neutral point potential of a stator winding of the motor 4; and a controller 1 that estimates a rotor position of the motor 4 based on the detected neutral point potential, and that controls the inverter 3 based on an estimation result. A ground potential of the controller 1 is set to a negative side potential or a positive side potential of a DC voltage that is supplied to the inverter 3. The voltage division circuit 2 detects the neutral point potential with reference to the negative side potential or the positive side potential. The controller 1 estimates the rotor position based on a difference between a first neutral point potential detected during the ON/OFF operation of the inverter 3 and a first fixed reference potential (⅔)Emax, and based on a difference between a second neutral point potential detected during the ON/OFF operation and a second fixed reference potential (⅓)Emax.

    摘要翻译: 电动机驱动装置1000包括:驱动电动机4的逆变器3,用作检测电动机4的定子绕组的中性点电位的中性点电位检测单元的分压电路2; 以及控制器1,其基于检测到的中性点电位来估计电动机4的转子位置,并且基于估计结果来控制逆变器3。 控制器1的接地电位被设置为提供给逆变器3的直流电压的负侧电位或正侧电位。分压电路2参考负侧电位或 正面潜力 控制器1基于在逆变器3的接通/断开操作期间检测到的第一中性点电位与第一固定参考电位(⅔)Emax之间的差异,并且基于第二中性点电位 在ON / OFF操作期间检测到第二固定参考电位(1/3)Emax。

    Pressure detection unit and information input device having the pressure detection unit
    130.
    发明授权
    Pressure detection unit and information input device having the pressure detection unit 有权
    压力检测单元和具有压力检测单元的信息输入装置

    公开(公告)号:US09007338B2

    公开(公告)日:2015-04-14

    申请号:US13701689

    申请日:2011-04-13

    摘要: A pressure detection unit is disposed in a peripheral portion of a panel member of an information input device for detecting a press operation to the panel member. The pressure detection unit includes a first substrate, a second substrate disposed to face the first substrate, a pressure sensitive layer disposed between the first substrate and the second substrate, and a first electrode provided on the first substrate and a second electrode provided on the second substrate for detecting resistance change via the pressure sensitive layer, the first electrode and the second electrode being provided at positions not facing each other along normal lines of the first substrate and the second substrate. The first electrode, the second electrode and the pressure sensitive layer together form a series circuit in the form of a loop.

    摘要翻译: 压力检测单元设置在用于检测对面板构件的按压操作的信息输入装置的面板构件的周边部分中。 压力检测单元包括第一基板,与第一基板相对设置的第二基板,设置在第一基板和第二基板之间的压敏层,以及设置在第一基板上的第一电极和设置在第二基板上的第二电极 用于通过压敏层检测电阻变化的基板,第一电极和第二电极设置在沿着第一基板和第二基板的法线彼此不相对的位置。 第一电极,第二电极和压敏层一起形成循环形式的串联电路。