Plasminogen activator covalently bonded to a porous body of
.beta.-tricalcium phosphate
    6.
    发明授权
    Plasminogen activator covalently bonded to a porous body of .beta.-tricalcium phosphate 失效
    共价键合到β-磷酸三钙的多孔体上的纤溶酶原激活物

    公开(公告)号:US5491082A

    公开(公告)日:1996-02-13

    申请号:US246940

    申请日:1994-05-20

    摘要: A plasminogen activator such as urokinase or tissue plasminogen activator is covalently bonded to a porous body composed of calcium phosphate to form a plasminogen activator-porous body complex. The tricalcium phosphate can be .alpha.-tricalcium phosphate, .beta.-tricalcium phosphate, hydroxyapatite, tetracalcium phosphate, octacalcium phosphate and mixtures thereof. In a preferred embodiment, .beta.-tricalcium phosphate which has excellent biocompatibility with the body or a mixture of .beta.-tricalcium phosphate and hydroxyapatite is used. Preferably, synthetic calcium phosphate is used is to avoid impurities contained by natural calcium phosphate. Covalent bonding is by crosslinking with glutaraldehyde, bismaleimides, dihalogenic aryls or diisocyanates, or by using cyanogen bromide, diazotization or periodic acid. The complex can be filled into a column to form a bioreactor. A granular complex can be intravascularly injected into the blood of a patient to provide thrombotic activity for a long period of time. In another embodiment, a complex of a predetermined shape can be implanted to provide thrombotic activity.

    摘要翻译: 纤维蛋白溶酶原激活剂如尿激酶或组织纤溶酶原激活剂共价键合到由磷酸钙组成的多孔体上以形成纤溶酶原激活剂多孔体复合体。 磷酸三钙可以是α-磷酸三钙,β-磷酸三钙,羟基磷灰石,磷酸四钙,磷酸八钙及其混合物。 在优选的实施方案中,使用与身体具有优异生物相容性的β-磷酸三钙或磷酸β-磷酸钙和羟基磷灰石的混合物。 优选地,合成磷酸钙是为了避免天然磷酸钙含有的杂质。 共价键是通过与戊二醛,双马来酰亚胺,二卤代芳基或二异氰酸酯交联,或通过使用溴化氰,重氮化或高碘酸进行交联。 复合物可以填充到柱中以形成生物反应器。 颗粒状复合物可以血管内注射到患者的血液中以长时间提供血栓形成活性。 在另一个实施方案中,可以植入预定形状的复合物以提供血栓形成活性。

    RECORDING MEDIUM CONVEYANCE GUIDE DEVICE, TRANSFER DEVICE, AND IMAGE FORMING APPARATUS
    9.
    发明申请
    RECORDING MEDIUM CONVEYANCE GUIDE DEVICE, TRANSFER DEVICE, AND IMAGE FORMING APPARATUS 审中-公开
    记录介质传输指南设备,传输设备和图像形成设备

    公开(公告)号:US20160370738A1

    公开(公告)日:2016-12-22

    申请号:US15173364

    申请日:2016-06-03

    申请人: Takahiro Suzuki

    发明人: Takahiro Suzuki

    IPC分类号: G03G15/16

    摘要: A recording medium conveyance guide device includes a conveyance guide disposed upstream from a transfer nip to transfer an image to a recording medium in a recording-medium conveyance direction, to at least partially contact the recording medium. The recording medium conveyance guide device further includes a drive device to move a leading edge of the conveyance guide from a first position to a second position closer to the transfer nip than the first position when the trailing edge of the recording medium approaches the leading edge of the conveyance guide.

    摘要翻译: 记录介质传送引导装置包括设置在转印夹持部的上游的输送引导件,以将记录介质输送方向的图像转印到记录介质上,至少部分地与记录介质接触。 记录介质传送引导装置还包括驱动装置,当记录介质的后缘接近记录介质的前缘时,驱动装置将输送引导件的前边缘从第一位置移动到比第一位置更靠近转印夹持口的第二位置 运输指南。

    Hydrogen production device
    10.
    发明授权
    Hydrogen production device 有权
    氢气生产装置

    公开(公告)号:US08999119B2

    公开(公告)日:2015-04-07

    申请号:US13702443

    申请日:2011-08-26

    摘要: The hydrogen production device of the present invention includes: a first electrode including a conductive substrate and a photocatalytic semiconductor layer; a second electrode that is electrically connected to the first electrode and disposed in a second region opposite to a first region relative to the first electrode; the first region is defined as a region on a side of a surface of the first electrode in which the photocatalytic semiconductor layer is provided; a water-containing electrolyte solution; and a housing containing these. The first electrode is provided with first through-holes and the second electrode is provided with second through-holes; and the first through-holes and second through-holes form a communicating hole for allowing the first region and the second region to communicate with each other. An ion exchange membrane having substantially the same shape as the communicating hole is disposed in the communicating hole to close the communicating hole.

    摘要翻译: 本发明的氢制造装置包括:第一电极,其包括导电性基板和光催化性半导体层; 第二电极,其电连接到第一电极并且设置在相对于第一电极与第一区域相反的第二区域中; 第一区域被定义为设置有光催化半导体层的第一电极的表面侧的区域; 含水电解质溶液; 和包含这些的房屋。 第一电极设置有第一通孔,第二电极设置有第二通孔; 并且第一通孔和第二通孔形成用于使第一区域和第二区域彼此连通的连通孔。 具有与连通孔大致相同形状的离子交换膜设置在连通孔中以闭合连通孔。