Abstract:
A phthalazinone ketone derivative as represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, a use thereof as a poly (ADP-ribose) polymerase (PARP) inhibitor, and a cancer treatment method thereof are described.
Abstract:
A compound of Formula I, or an isomer, pharmaceutically acceptable salt or solvate thereof, is provided. Also, a composition containing a compound of Formula I, or an isomer, pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents, is provided. Further, use of a compound of Formula I, or an isomer, pharmaceutically acceptable salt or solvate thereof for anti-apoptosis is provided, preventing or treating a disease or disorder associated with apoptosis; especially for protecting cardiomyocyte, preventing or treating a disease or disorder associated with cardiomyocyte apoptosis.
Abstract:
A vehicular torsion bar suspension device, which comprises a front torsion bar spring and a rear torsion bar spring respectively installed at front and rear suspensions of the vehicle. The opposite ends of the front and rear torsion bar springs on the same side are connected mutually by a connection mechanism, and are connected with a vehicle frame through a positioning device. The connection mechanism is mounted between the front and rear torsion bar springs on the same side, so that a linkage relationship is established between the front and rear torsion bar springs. The device improves the vibration situation of the vehicle when driving the vehicle on an uneven ground, and prevents the vehicle frame and vehicle body skeleton from suffering torsional force. As a result, the usage life of the vehicle is prolonged.
Abstract:
A line-start brushless permanent magnet motor assembly includes an unconventional combination of a rotor assembly including a plurality of permanent magnets mounted thereon, and a stator assembly including aluminum winding coils. The unique combination of construction features leads to significant motor performance enhancements at lower incremental cost. The line-start brushless permanent magnet motor assembly may be incorporated into a hermetic compressor, such as may be used in an air conditioning system, to meet high efficiency standards (e.g., seasonal efficiency energy rating). The disclosed embodiments have an efficiency of at least 90% with winding coils consisting essentially entirely of aluminum.
Abstract:
A current perpendicular to plane magneto-resistance effect element includes: a magneto-resistance effect film comprised of a fixed magnetization layer, a free magnetization layer, and a complex spacer layer including an insulating layer and current paths formed through the insulating layer; a biasing mechanism for stabilizing the free magnetization layer; a shielding mechanism for ensuring a reproducing resolution of the magneto-resistance effect element; and a pair of electrodes for flowing a current perpendicular to a film surface of the magneto-resistance effect element; wherein a resistance area product (RA:Ω×μm2) is set to 0.00062×√{square root over ((GAP))}×TW+0.06 when a track width of the magneto-resistance effect element is defined as TW (nm) and a gap length of the magneto-resistance effect element is defined as GAP (nm).
Abstract:
An improved system and method for generating an online summary of a collection of documents is provided. A list of documents may be received, and the titles of the list of documents may be obtained. A set of terms that frequently occur in the titles of the documents may be iteratively expanded and overlapping phrases may be merged until there may be no more terms that occur in the titles with a frequency that exceeds a predefined threshold. In an embodiment, an article summarizer operably coupled to a search engine may be provided to generate a summary of a list of references to web pages in search results using titles of the web pages. The summary of the web pages may then be sent with the list of references to the web pages as search results to a client device for display to a user.
Abstract:
Techniques for determining when and how to transform words in a query to its plural or non-plural form in order to provide the most relevant search results while minimizing computational overhead are provided. A dictionary is generated based upon the words used in a specified number of previous most frequent search queries and comprises lists of transformations from plural to singular and singular to plural. Unnecessary transformations are removed from the dictionary based upon language modeling. The word to transform is determined by finding the last non-stop re-writable word of the query. The context of the transformed word is confirmed in the search documents and a version of the query is executed using both the original form of the word and the transformation of the word.
Abstract:
The configurations of a buck type and a buck/boost type converter systems and a controlling method thereof are provided in the present invention. The proposed buck/boost type converter system includes a rectifier bridge, a first auxiliary circuit including a first unidirectional switch coupled to the rectifier bridge and a second unidirectional switch coupled to the first unidirectional switch, a first capacitor coupled to the first unidirectional switch and the rectifier bridge, a buck/boost converter having a first input terminal coupled to the first unidirectional switch, a second input terminal coupled to the first capacitor, a first output terminal coupled to the second unidirectional switch and a second output terminal, a second capacitor electrically connected to the first and the second output terminals in parallel, and a DC source coupled to the second unidirectional switch.
Abstract:
The educational adaptive provider architecture described herein provides a way for an educational services framework to be built on varying underlying existing technologies without any changes in the object model and services. The provider framework supports the ability to have multiple types of providers for various services, such as, for example, for authorization, authentication, communication, grouping, scoring, social-networking, storage and user functions. The educational adaptive provider architecture provides easy integration of existing institutional and educational service deployments.
Abstract:
The present invention relates to a method for adjusting forward transmission power control threshold in a mobile communication system, comprising the following steps of: setting in advance at the base station side an overload control threshold and an adjustment range of the power control threshold of sector forward transmission power; obtaining current total values of the forward transmission power of the sector; judging whether the sector forward transmission power exceeds said overload control threshold; judging whether the sector forward transmission power exceeds said adjustment range of the control threshold; dynamically adjusting the forward transmission power threshold, and so on. By the steps of pre-setting the overload control threshold and power control threshold adjustment range of the sector forward transmission power, obtaining the current total values of the forward transmission power of the whole sector and judging whether the sector forward transmission power exceeds the overload threshold and so on, the present invention realizes real-time regulation of the sector forward transmission power, thereby can track the variance of the actual forward transmission power, and ensure CDMA mobile communication system having a good communication service quality.