PROTEIN MARKERS IDENTIFICATION FOR GASTRIC CANCER DIAGNOSIS
    144.
    发明申请
    PROTEIN MARKERS IDENTIFICATION FOR GASTRIC CANCER DIAGNOSIS 审中-公开
    蛋白质标记鉴定胃癌诊断

    公开(公告)号:US20120053080A1

    公开(公告)日:2012-03-01

    申请号:US13255527

    申请日:2010-02-19

    CPC分类号: G01N33/57484

    摘要: Methods for detecting cancer as well as methods of diagnosis of cancer by detecting proteins secreted into biological fluids are disclosed The invention was first applied to detecting proteins secreted into serum and urine However, it is understood that the methods have broader application to developing tools and systems for detecting proteins secreted into other biological fluids such as, but not limited to, saliva, spinal fluid, seminal fluid, vaginal fluid, and ocular fluid Reliable detection of proteins secreted into biological fluids provided by embodiments of the methods will enable more timely and accurate detection and diagnosis of cancer.

    摘要翻译: 本发明首先应用于检测分泌到血清和尿液中的蛋白质,但是应当理解,该方法在开发工具和系统方面有更广泛的应用 用于检测分泌到其它生物流体中的蛋白质,例如但不限于唾液,脊髓液,精液,阴道液和眼液可以通过该方法的实施方案提供的分泌到生物流体中的蛋白质的可靠检测将能够更及时和准确 检测和诊断癌症。

    Novel Lipolytic Enzyme ELIP
    145.
    发明申请
    Novel Lipolytic Enzyme ELIP 失效
    新型脂肪分解酶ELIP

    公开(公告)号:US20110312028A9

    公开(公告)日:2011-12-22

    申请号:US12786024

    申请日:2010-05-24

    CPC分类号: C11D3/38627 C12N9/18 C12N9/20

    摘要: The present invention provides a novel nucleic acid sequence, designated ELIP, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding at least one novel lipolytic enzyme, recombinant lipolytic enzyme proteins and methods for producing the same.

    摘要翻译: 本发明提供了编码脂肪分解酶和相应的编码氨基酸序列的命名为ELIP的新型核酸序列。 本发明还提供了表达载体和宿主细胞,其包含编码至少一种新型脂肪分解酶,重组脂肪分解酶蛋白质的核酸序列及其制备方法。

    ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES
    147.
    发明申请
    ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES 审中-公开
    具有改性性质的ALPHA-AMYLASE变体

    公开(公告)号:US20110269210A1

    公开(公告)日:2011-11-03

    申请号:US13151905

    申请日:2011-06-02

    申请人: Mee-Young Yoon

    发明人: Mee-Young Yoon

    摘要: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and that exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions generally comprise at least one of an additional enzyme, a detergent,.a surfactant, a chelator, an oxidizing agent, an acidulant, an alkalizing agent, a source of peroxide, a source of hardness, a salt, a detergent complexing agent, a polymer, a stabilizing agent, or a fabric conditioner. Also disclosed are detergent formulations comprising the variants. Methods of using the compositions for desizing woven material and washing or cleaning items, such as dishes or laundry, are disclosed. Kits related thereto are also provided.

    摘要翻译: 公开了包含α-淀粉酶变体的组合物,其具有α-淀粉酶活性,并且相对于其来源的亲本AmyS样α-淀粉酶表现出改变的性质。 组合物通常包含另外的酶,洗涤剂,表面活性剂,螯合剂,氧化剂,酸化剂,碱化剂,过氧化物源,硬度源,盐,洗涤剂络合剂中的至少一种 ,聚合物,稳定剂或织物调理剂。 还公开了包含这些变体的洗涤剂制剂。 公开了将组合物用于脱浆织物和洗涤或清洁物品如餐具或衣物的方法。 还提供了与之相关的试剂盒。

    PROTEASES AND VARIANTS THEREOF
    149.
    发明申请
    PROTEASES AND VARIANTS THEREOF 失效
    保护者及其变体

    公开(公告)号:US20110117624A1

    公开(公告)日:2011-05-19

    申请号:US13014100

    申请日:2011-01-26

    摘要: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.

    摘要翻译: 本发明涉及RP-II型分离的蛋白酶和与亲本RP-II蛋白酶相比表现出改进性质的RP-II蛋白酶的变体,DNA构建体和编码所述蛋白酶和变体的表达的载体,具有宿主细胞能力 从DNA构建体表达蛋白酶和变体,以及通过培养所述宿主细胞产生它们的方法。 蛋白酶可以有利地用作洗涤剂组合物和添加剂中的组分,任选地与其它酶如蛋白酶,脂肪酶,纤维素酶,淀粉酶,过氧化物酶或氧化酶组合使用。