公开(公告)号：US09851301B2

公开(公告)日：2017-12-26

申请号：US15081361

申请日：2016-03-25

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Steffen Mueller

IPC: G01N21/59 ,  G01N33/49 ,  G01N15/04 ,  G01N21/31 ,  B01L3/00 ,  G01N35/00 ,  G01N21/84

CPC classification number: G01N21/59 ,  B01L3/5021 ,  G01N15/042 ,  G01N21/3151 ,  G01N33/49 ,  G01N33/491 ,  G01N35/0099 ,  G01N2015/045 ,  G01N2021/8405 ,  G01N2035/00495

Abstract: A method for automated identification of a state of a sample such as, for example, for identifying whether or not the sample was centrifuged is presented. A device for analyzing samples and a laboratory automation system are also presented in which the method is applied.

公开(公告)号：US20170350912A1

公开(公告)日：2017-12-07

申请号：US15600089

申请日：2017-05-19

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Marco Maetzler ,  Liutger Joannes Franzen ,  Florian Zwahlen ,  Hans Reischauer ,  Adrian Cojocaru ,  Stephan Topsakalian

IPC: G01N35/10 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N35/1002 ,  G01N35/00663 ,  G01N35/00871 ,  G01N35/0099 ,  G01N35/04 ,  G01N2035/0498 ,  G06Q10/087

Abstract: A method for supplying consumable items to an automated sample analyzer is presented. The automated analyzer comprises a consumable repository including two or more storage areas. Each area is configured to store a plurality of consumable items. The method comprises receiving one or more orders for analytical tests to be carried out by the analyzer, reserving consumable items corresponding to one or more sets of consumable items required for the analytical tests in a first area, switching to a second area for reserving consumable items in response to determining that a predetermined consumable item in the first area has been reserved, supplying the reserved consumable items for use in the one or more analytical tests and indicating that the first area can be replenished in response to determining that a particular consumable item of the first storage area has been used.

公开(公告)号：US09835531B2

公开(公告)日：2017-12-05

申请号：US14615700

申请日：2015-02-06

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Herfried Huemer

IPC: G01N1/40 ,  G01N33/49 ,  B01D63/08 ,  B01D24/30 ,  B01L3/00

CPC classification number: G01N1/4077 ,  B01D24/30 ,  B01D63/08 ,  B01D2313/24 ,  B01D2313/50 ,  B01D2315/05 ,  B01L3/5021 ,  B01L2300/047 ,  B01L2300/0681 ,  B01L2400/0478 ,  G01N33/491 ,  G01N2001/4088

Abstract: A separation device for separating a filtrate from a sample fluid, especially for extracting plasma from whole blood, comprising a sample container for receiving the sample fluid and a filter plunger to be introduced under seal into the sample container, which filter plunger has a filter element at its front end and a grip element on the opposite end and will receive in its interior the filtrate obtained. After insertion of the filter plunger into the sample container an annular chamber is formed between the inner wall of the sample container and the outer wall of the filter plunger, which is sealed against the exterior by a sealing lip and in which an air cushion is formed upon introduction of the filter plunger into the sample container, which acts on the sample fluid. A flow connection is provided between the annular chamber and the front side of the filter element after insertion of the filter plunger is terminated.

公开(公告)号：USD804033S1

公开(公告)日：2017-11-28

申请号：US29583390

申请日：2016-11-04

Applicant: Roche Diagnostics Operations, Inc.

Designer： Craig Ian Wightman ,  Johann Florian Wassermann ,  Michael John Unwin

公开(公告)号：US09830673B2

公开(公告)日：2017-11-28

申请号：US14172585

申请日：2014-02-04

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Eric S. Carlsgaard ,  Aaron H. Dinwiddie ,  Igor Gejdos ,  Michael L. Long ,  Teresa J. Oelmann

IPC: G06Q50/22 ,  G06F19/00

CPC classification number: G06Q50/22 ,  G06F19/00 ,  G16H10/60 ,  G16H40/63 ,  G16H40/67

Abstract: A computer-implemented method for managing accounts in a diabetes management system. The method includes receiving, by an account manager, a request to deactivate a first account associated with a healthcare provider. The first account may be associated with a plurality of patient accounts. The account manager may be implemented as computer executable instructions executing on a computer processor of a server device. The method includes removing, by the account manager, access to data associated with the first account. Each of the patient accounts associated with the first account are identified and may be deactivated by the account manager. An electronic notification may be sent to a person associated with each of the identified patient accounts, advising the person that the corresponding patient account has been deactivated. An audit record may be created in a data store, the audit record indicating the deactivation of the first account.

公开(公告)号：US09810705B2

公开(公告)日：2017-11-07

申请号：US15249565

申请日：2016-08-29

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Thomas Meyer ,  Gottlieb Schacher ,  Rolf Sigrist ,  Christian Guzek

IPC: G01N35/02 ,  G01N35/10 ,  G01N35/00 ,  G01N33/86

CPC classification number: G01N35/0092 ,  G01N33/86 ,  G01N35/026 ,  G01N35/1002 ,  G01N35/1065 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/0094 ,  Y10T436/113332 ,  Y10T436/114165 ,  Y10T436/115831 ,  Y10T436/2575

Abstract: A method and system for automatic in-vitro diagnostic analysis are described. The method includes adding a first reagent type and a second reagent type to a first test liquid during a first and second cycle times respectively. The addition of the first reagent type to the first test liquid includes parallel addition of a second reagent type to a second test liquid during the first cycle time. The addition of the second reagent type to the first test liquid includes parallel addition of a first reagent type to a third test liquid during the second cycle time, respectively.

公开(公告)号：US20170311892A9

公开(公告)日：2017-11-02

申请号：US13930785

申请日：2013-06-28

Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.

Inventor： Stephan-Michael Frey ,  Oliver Kube

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61N1/05

CPC classification number: A61B5/6846 ,  A61B5/14532 ,  A61B5/14865 ,  A61B2562/12 ,  A61N1/0504 ,  Y10T29/49155

Abstract: A biosensor is proposed for insertion into the subcutaneous tissue of a user wherein the biosensor includes at least one flexible substrate (2) and at least one electrode (5) on at least one surface (9) of the substrate and at least one contacting element (3). The contacting element is connected to the electrode. The substrate has at least one kink (4), at which the substrate is at least partly kinked such that the surface is subdivided into at least two interconnected outer surfaces (9a, 9b, 9c).

公开(公告)号：US20170296078A1

公开(公告)日：2017-10-19

申请号：US15132318

申请日：2016-04-19

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Mathias Emil Egermark ,  Edelgard Anna Kaiser ,  Ursula-Henrike Wienhues-Thelen ,  Christian Zaugg ,  Andre Ziegler ,  Marten Rosenquist ,  Viveka Frykmann-Kull ,  Emma Svennberg ,  Leif Friberg

IPC: A61B5/046 ,  A61B5/0408 ,  A61B5/0404 ,  G01N33/68

CPC classification number: A61B5/046 ,  A61B5/0404 ,  A61B5/04085 ,  A61B2560/0468 ,  G01N33/74 ,  G01N2800/326

Abstract: The present invention relates to a method of diagnosing whether a subject with no known history of atrial fibrillation is suffering from atrial fibrillation, or not, said method comprising the steps of a) determining the amount of a BNP-type peptide in a sample of said subject; b) comparing the amount the BNP-type peptide to a reference, and c) assessing intermittent ECG recordings obtained from said subject over a period of at least one week by using a handheld ECG device.

公开(公告)号：US20170292148A1

公开(公告)日：2017-10-12

申请号：US15626641

申请日：2017-06-19

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Christian Birkner

IPC: C12Q1/68

CPC classification number: C12Q1/689 ,  C12Q1/6848 ,  C12Q2527/125

Abstract: The present disclosure provides a method and system for the PCR amplification of a target sequence which suppresses non-specific amplification products. The disclosure concerns the use of a primer pair optimized to amplify a nucleic acid of a contaminant in the background of genomic DNA of a first organism. When DNA from a second organism suspected for comprising the contaminant is subjected to the same PCR-based amplification reaction, detection sensitivity and specificity of the contaminant is enhanced when an amount of genomic DNA of the first organism is present in the amplification reaction.

公开(公告)号：US20170269068A1

公开(公告)日：2017-09-21

申请号：US15614856

申请日：2017-06-06

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Elke Faatz ,  Michael Gerg ,  Hans-Peter Josel ,  Christian Vogl

IPC: G01N33/537 ,  G01N33/82 ,  C07K16/26 ,  G01N33/541

CPC classification number: G01N33/537 ,  C07K16/26 ,  G01N33/541 ,  G01N33/82

Abstract: The present invention concerns an in vitro method for measurement of 25-hydroxyvitamin D, wherein the potentially interfering compound 24,25-dihydroxyvitamin D3 is blocked by a binding agent specifically binding to 24,25-dihydroxyvitamin D3 and not binding to 25-hydroxyvitamin D.