公开(公告)号：US09457146B2

公开(公告)日：2016-10-04

申请号：US14144373

申请日：2013-12-30

Applicant: DexCom, Inc.

Inventor： John Michael Dobbles ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  James H. Brauker

IPC: A61M5/172 ,  A61B5/145 ,  A61M5/142 ,  G06F19/00 ,  A61B5/00 ,  A61M5/00 ,  A61M5/178 ,  A61M5/30 ,  A61M11/00 ,  A61M15/00

CPC classification number: A61M5/1723 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14546 ,  A61M5/003 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/178 ,  A61M5/20 ,  A61M5/30 ,  A61M11/00 ,  A61M15/00 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/008 ,  A61M15/0083 ,  A61M35/00 ,  A61M2005/14296 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/587 ,  A61M2205/8206 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468 ,  G16H40/63

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

公开(公告)号：US20150351683A1

公开(公告)日：2015-12-10

申请号：US14830568

申请日：2015-08-19

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Mark A. Tapsak ,  Sean T. Saint ,  Apurv Ullas Kamath ,  Paul V. Neale ,  Peter C. Simpson ,  Michael Robert Mensinger ,  Dubravka Markovic

IPC: A61B5/00 ,  A61M5/172 ,  A61M11/00 ,  A61B5/1486 ,  A61M15/00 ,  A61B5/145 ,  A61M5/315

CPC classification number: A61M5/31525 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/4839 ,  A61B2560/0443 ,  A61M5/1723 ,  A61M11/00 ,  A61M15/0001 ,  A61M2005/1726 ,  A61M2205/18 ,  A61M2205/3303 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468 ,  G16H20/17 ,  G16H40/63

Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

公开(公告)号：US20150087942A1

公开(公告)日：2015-03-26

申请号：US14552398

申请日：2014-11-24

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Apurv Ullas Kamath

IPC: A61B5/1473 ,  A61B5/1495 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/1473 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/1411 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/15142 ,  A61B5/72 ,  A61B5/742 ,  A61B5/746

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20240138717A1

公开(公告)日：2024-05-02

申请号：US18375841

申请日：2023-10-02

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/1486 ,  C12Q1/00

CPC classification number: A61B5/14532 ,  A61B5/1486 ,  A61B5/14865 ,  C12Q1/001 ,  C12Q1/006 ,  B33Y80/00

Abstract: Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.

公开(公告)号：US20240108258A1

公开(公告)日：2024-04-04

申请号：US18485012

申请日：2023-10-11

Applicant: Dexcom, Inc.

Inventor： James H. Brauker ,  Peter C. Simpson ,  Robert J. Boock ,  Monica Rixman Swinney ,  Mark C. Brister

IPC: A61B5/1486 ,  A61B5/00 ,  A61B5/145 ,  C12Q1/00 ,  G01N33/543 ,  G01N33/66

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/411 ,  A61B5/6848 ,  C12Q1/006 ,  G01N33/54366 ,  G01N33/66 ,  A61B5/1473

Abstract: The present invention relates generally to biointerface membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel biointerface membranes, to devices and implantable devices including these membranes, methods for forming the biointerface membranes on or around the implantable devices, and to methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device.

公开(公告)号：US20240081693A1

公开(公告)日：2024-03-14

申请号：US18514803

申请日：2023-11-20

Applicant: Dexcom, Inc.

Inventor： Apurv U. Kamath ,  Jack Pryor ,  Paul Goode ,  James H. Brauker ,  Aarthi Mahalingam

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/05 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/15 ,  A61B17/34

CPC classification number: A61B5/14532 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/0031 ,  A61B5/05 ,  A61B5/1411 ,  A61B5/14503 ,  A61B5/14507 ,  A61B5/1451 ,  A61B5/14514 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14735 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/6801 ,  A61B5/6833 ,  A61B5/68335 ,  A61B5/6848 ,  A61B5/6849 ,  A61B5/72 ,  A61B17/3468 ,  A61B5/150022 ,  A61M5/1723

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US11638541B2

公开(公告)日：2023-05-02

申请号：US16554419

申请日：2019-08-28

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Victoria E. Carr-Brendel ,  Paul V. Goode, Jr. ,  Apurv Ullas Kamath ,  James Patrick Thrower ,  Ben Xavier

IPC: A61B5/145 ,  A61B5/1468 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/00 ,  G16Z99/00 ,  A61M5/172 ,  A61B5/1473

Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.

公开(公告)号：US11564602B2

公开(公告)日：2023-01-31

申请号：US15347687

申请日：2016-11-09

Applicant: DexCom, Inc.

Inventor： Andrew P. Rasdal ,  James H. Brauker ,  Paul V. Neale ,  Peter C. Simpson

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/07 ,  A61B5/145 ,  A61B5/1486

Abstract: A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.

公开(公告)号：US20220203038A1

公开(公告)日：2022-06-30

申请号：US17696198

申请日：2022-03-16

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Mark A. Tapsak ,  Sean T. Saint ,  Apurv Ullas Kamath ,  Paul V. Neale ,  Peter C. Simpson ,  Michael Robert Mensinger ,  Dubravka Markovic

IPC: A61M5/315 ,  A61M11/00 ,  A61M5/172 ,  G16H20/17 ,  A61M15/00 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  G16H10/40 ,  G16H40/63

Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

公开(公告)号：US11246990B2

公开(公告)日：2022-02-15

申请号：US15906946

申请日：2018-02-27

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Mark A. Tapsak ,  Sean T. Saint ,  Apurv Ullas Kamath ,  Paul V. Neale ,  Peter C. Simpson ,  Michael Robert Mensinger ,  Dubravka Markovic

IPC: A61M31/00 ,  A61M1/00 ,  A61M5/315 ,  A61B5/1486 ,  A61M15/00 ,  A61M11/00 ,  A61B5/00 ,  A61B5/145 ,  A61M5/172 ,  G16H40/63 ,  G16H10/40 ,  G16H20/17

Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.