公开(公告)号：US10238324B2

公开(公告)日：2019-03-26

申请号：US14717967

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/01 ,  A61B5/11 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1473 ,  A61M5/172 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US10238322B2

公开(公告)日：2019-03-26

申请号：US14717643

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/01 ,  A61B5/11 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1473 ,  A61M5/172 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US10188333B2

公开(公告)日：2019-01-29

申请号：US15680053

申请日：2017-08-17

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  Peter C. Simpson ,  James H. Brauker ,  Paul V. Goode, Jr.

IPC: A61B5/05 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/1495 ,  A61B5/00 ,  B33Y80/00 ,  B33Y70/00

Abstract: Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.

公开(公告)号：US20180368774A1

公开(公告)日：2018-12-27

申请号：US16016497

申请日：2018-06-22

Applicant: DexCom, Inc.

Inventor： John Michael Gray ,  Jennifer Blackwell ,  Paul V. Neale ,  Justen Deering England ,  Andrew Joncich ,  Cameron Brock ,  Peter C. Simpson ,  Thomas Metzmaker ,  Neel Narayan Shah ,  Mark Douglas Kempkey ,  Patrick John Castagna ,  Warren Terry ,  Jason Halac ,  Christian Michael Andre George ,  Daniel E. Apacible ,  John Charles Barry ,  Maria Noel Brown Wells ,  Kenneth Pirondini ,  Andrew Michael Reinhardt ,  Jason C. Wong ,  Remy E. Gagnon ,  David DeRenzy ,  Randall Scott Koplin ,  Alan Baldwin ,  Young Woo Lee ,  David A. Keller ,  Louise Emma van den Heuvel ,  Carol Wood Sutherland

IPC: A61B5/00 ,  A61B5/145

Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.

公开(公告)号：US20180368773A1

公开(公告)日：2018-12-27

申请号：US16016493

申请日：2018-06-22

Applicant: DexCom, Inc.

Inventor： John Michael Gray ,  Jennifer Blackwell ,  Paul V. Neale ,  Justen Deering England ,  Andrew Joncich ,  Cameron Brock ,  Peter C. Simpson ,  Thomas Metzmaker ,  Neel Narayan Shah ,  Mark Douglas Kempkey ,  Patrick John Castagna ,  Warren Terry ,  Jason Halac ,  Christian Michael Andre George ,  Daniel E. Apacible ,  John Charles Barry ,  Maria Noel Brown Wells ,  Kenneth Pirondini ,  Andrew Michael Reinhardt ,  Jason C. Wong ,  Remy E. Gagnon ,  David DeRenzy ,  Randall Scott Koplin ,  Alan Baldwin ,  Young Woo Lee ,  David A. Keller ,  Louise Emma van den Heuvel ,  Carol Wood Sutherland

IPC: A61B5/00 ,  A61B5/145

Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.

公开(公告)号：US20180368771A1

公开(公告)日：2018-12-27

申请号：US16016354

申请日：2018-06-22

Applicant: DexCom, Inc.

Inventor： John Michael Gray ,  Jennifer Blackwell ,  Paul V. Neale ,  Justen Deering England ,  Andrew Joncich ,  Cameron Brock ,  Peter C. Simpson ,  Thomas Metzmaker ,  Neel Narayan Shah ,  Mark Douglas Kempkey ,  Patrick John Castagna ,  Warren Terry ,  Jason Halac ,  Christian Michael Andre George ,  Daniel E. Apacible ,  John Charles Barry ,  Maria Noel Brown Wells ,  Kenneth Pirondini ,  Andrew Michael Reinhardt ,  Jason C. Wong ,  Remy E. Gagnon ,  David DeRenzy ,  Randall Scott Koplin ,  Alan Baldwin ,  Young Woo Lee ,  David A. Keller ,  Louise Emma van den Heuvel ,  Carol Wood Sutherland

IPC: A61B5/00 ,  A61B5/145

Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.

公开(公告)号：US20180303417A1

公开(公告)日：2018-10-25

申请号：US16017703

申请日：2018-06-25

Applicant: DexCom, Inc.

Inventor： Michael Robert Mensinger ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  David DeRenzy ,  Arturo Garcia ,  Indrawati Gauba ,  Ashley Hall ,  Thomas Hall ,  Hari Hampapuram ,  Murrad Kazalbash ,  Aarthi Mahalingam ,  Jack Pryor ,  Anna Leigh Davis ,  Eli Reihman ,  Kenneth San Vicente ,  Peter C. Simpson ,  Alexander Steele ,  Jorge Valdes ,  Michael J. Estes ,  Eric Cohen

IPC: A61B5/00 ,  G16H10/40 ,  A61B5/145 ,  G16H40/63 ,  G16H40/40

CPC classification number: A61B5/6801 ,  A61B5/0004 ,  A61B5/0022 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/486 ,  A61B5/6898 ,  A61B5/72 ,  A61B5/742 ,  A61B5/7435 ,  A61B5/7475 ,  F04C2270/041 ,  G06F19/00 ,  G06F19/3468 ,  G16H10/40 ,  G16H40/40 ,  G16H40/63

Abstract: The present embodiments harness a wide variety of capabilities of modern smartphones, and combine these capabilities with information from a continuous glucose monitor to provide diabetics and related people with more information than the continuous glucose monitor can provide by itself. The increased information provides the diabetic with an increased likelihood of good diabetes management for better health.

公开(公告)号：US20180182491A1

公开(公告)日：2018-06-28

申请号：US15853493

申请日：2017-12-22

Applicant: DexCom, Inc.

Inventor： Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Darin Edward Chum Dew ,  Eric Cohen ,  Anna Leigh Davis ,  Mark Dervaes ,  Laura J. Dunn ,  Minda McDorman Grucela ,  Hari Hampapuram ,  Matthew Lawrence Johnson ,  Apurv Ullas Kamath ,  Steven David King ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Zebediah L. McDaniel ,  Sumitaka Mikami ,  Subrai Girish Pai ,  Philip Mansiel Pellouchoud ,  Stephen Alan Reichert ,  Eli Reihman ,  Peter C. Simpson ,  Brian Christopher Smith ,  Stephen J. Vanslyke ,  Robert Patrick Van Tassel ,  Matthew D. Wightlin ,  Richard C. Yang ,  James Stephen Amidei ,  David Derenzy ,  Benjamin Elrod West ,  Vincent Crabtree ,  Michael Levozier Moore ,  Douglas William Burnette ,  Alexandra Elena Constantin ,  Nicholas Polytaridis ,  Dana Charles Cambra ,  Abhishek Sharma ,  Kho Braun ,  Patrick Wile McBride

IPC: G16H50/30 ,  G16H40/63 ,  G16H80/00 ,  H04W12/06 ,  H04W4/80 ,  A61B5/145 ,  A61B5/00 ,  A61M5/142

CPC classification number: G16H50/30 ,  A43B3/0005 ,  A61B5/0004 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4839 ,  A61M5/142 ,  A61M5/1723 ,  A61M2205/18 ,  A61M2205/3303 ,  A61M2205/3507 ,  A61M2205/3569 ,  A61M2205/3576 ,  G06Q2220/14 ,  G16H20/10 ,  G16H20/17 ,  G16H40/40 ,  G16H40/63 ,  G16H50/20 ,  G16H80/00 ,  H04L63/0428 ,  H04L63/06 ,  H04L63/0876 ,  H04L2209/80 ,  H04W4/38 ,  H04W4/80 ,  H04W12/02 ,  H04W12/04 ,  H04W12/06 ,  H04W52/0251 ,  Y02A90/26 ,  Y02D70/10 ,  Y02D70/1224 ,  Y02D70/1242 ,  Y02D70/1262 ,  Y02D70/14 ,  Y02D70/142 ,  Y02D70/144 ,  Y02D70/162 ,  Y02D70/164 ,  Y02D70/166 ,  Y02D70/20 ,  Y02D70/22 ,  Y02D70/26

Abstract: Systems and methods disclosed provide ways for Health Care Professionals (HCPs) to be involved in initial patient system set up so that the data received is truly transformative, such that the patient not just understands what all the various numbers mean but also how the data can be used. For example, in one implementation, a CGM device is configured for use by a HCP, and includes a housing and a circuit configured to receive a signal from a transmitter coupled to an indwelling glucose sensor. A calibration module converts the received signal into clinical units. A user interface is provided that is configured to display a measured glucose concentration in the clinical units. The user interface is further configured to receive input data about a patient level, where the input data about the patient level causes the device to operate in a mode appropriate to the patient level.

公开(公告)号：US09996668B2

公开(公告)日：2018-06-12

申请号：US15287450

申请日：2016-10-06

Applicant: DexCom, Inc.

Inventor： Eli Reihman ,  Sebastian Bohm ,  Leif N. Bowman ,  Katherine Yerre Koehler ,  Disha B. Sheth ,  Peter C. Simpson ,  Jim Stephen Amidei ,  Douglas William Burnette ,  Michael Robert Mensinger ,  Eric Cohen ,  Hari Hampapuram ,  Phil Mayou

IPC: G06T11/20 ,  G06F19/00 ,  A61B5/00 ,  A61B5/145 ,  G06F21/62 ,  G06F3/14 ,  G06T11/00 ,  G09G5/377 ,  H04W12/06 ,  G06F17/30 ,  H04W12/02

CPC classification number: G16H40/63 ,  A61B5/0004 ,  A61B5/14532 ,  A61B5/7275 ,  A61B5/746 ,  G06F3/14 ,  G06F3/1415 ,  G06F17/30867 ,  G06F17/30979 ,  G06F19/00 ,  G06F19/322 ,  G06F19/3406 ,  G06F19/3418 ,  G06F19/3487 ,  G06F21/6245 ,  G06Q2220/10 ,  G06T11/001 ,  G06T11/206 ,  G09G5/377 ,  G09G2354/00 ,  G09G2370/10 ,  G09G2370/16 ,  G16H10/60 ,  G16H15/00 ,  G16H40/67 ,  H04W12/02 ,  H04W12/06

Abstract: Methods and apparatus, including computer program products, are provided for backfilling. In some example embodiments, there is provided a method that includes receiving, at a receiver, backfill data representative of sensor data stored, at a continuous blood glucose sensor and transmitter assembly, due to a loss of a wireless link between the receiver and the continuous blood glucose sensor and transmitter assembly; generating, at the receiver, at least one of a notification or a graphically distinct indicator for presentation at a display of the receiver, the at least one of the notification or the graphically distinct indicator enabling the backfill data to be graphically distinguished, when presented at the display, from non-backfill data; and generating, at the receiver, a view including the backfill data, the non-backfill data, and the generated at least one of the notification or the graphically distinct indicator. Related systems, methods, and articles of manufacture are also described.

公开(公告)号：US09993186B2

公开(公告)日：2018-06-12

申请号：US15429022

申请日：2017-02-09

Applicant: DexCom, Inc.

Inventor： James R. Petisce ,  Mark A. Tapsak ,  Peter C. Simpson ,  Victoria Carr-Brendel ,  James H. Brauker

IPC: A61B5/1473 ,  A61B5/145 ,  A61B5/1486

CPC classification number: A61B5/1473 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/14735 ,  A61B5/14865

Abstract: The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic reaction, wherein the membrane system includes a polymer formed from a high oxygen soluble material. The high oxygen soluble polymer material is disposed adjacent to an oxygen-utilizing source on the implantable device so as to dynamically retain high oxygen availability to the oxygen-utilizing source during oxygen deficits. Membrane systems of the preferred embodiments are useful for implantable devices with oxygen-utilizing sources and/or that function in low oxygen environments, such as enzyme-based electrochemical sensors and cell transplantation devices.