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公开(公告)号：US20240151714A1
公开(公告)日：2024-05-09
申请号：US18281460
申请日：2022-03-14
发明人： Tae Hyeon YOO , Hyeon Ji PARK
IPC分类号： G01N33/53 , G01N33/573 , G01N33/68 , G01N33/74 , G01N33/76
CPC分类号： G01N33/5308 , G01N33/573 , G01N33/6887 , G01N33/74 , G01N33/76 , G01N2333/4712 , G01N2333/59 , G01N2333/71 , G01N2333/96463
摘要： The present invention relates to a target analyte detection composition based on a proximity proteolysis reaction and a target analyte detection method using same. More specifically, the present invention relates to a method for detecting a target analyte, the method comprising a step in which when a first binder and a second binder bind to the target analyte, hybridization is made between ssDNA linked to the first binder and ssDNA linked to a protease and between ssDNA linked to the second binder and ssDNA linked to a zymogen, whereby a signal generated by a proximity proteolysis reaction between the protease and the zymogen is detected.
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公开(公告)号：US20240132458A1
公开(公告)日：2024-04-25
申请号：US18275470
申请日：2022-01-28
发明人： Sangdun CHOI , Muhammad HASEEB , Javaid NASIR , Yasmeen FARZANA , Jee Yeon SEO , Jae Kyung HEO , Ho Chul SHIN
IPC分类号： C07D277/82 , A61P25/28 , C07D417/12
CPC分类号： C07D277/82 , A61P25/28 , C07D417/12
摘要： A NLRP3-inhibitory compound 7 (NIC7) and a potent derivative NIC7w are disclosed. NLRP3-inhibitory compound 7 (NIC7) and a potent derivative NIC7w are a novel small-molecule inhibitor for inhibiting NLRP3 inflammasomes are identified. These compounds inhibit main elements of the NLRP3 signaling pathway, primarily IL-1β and caspase 1, and improve cognitive behaviors of mice in Alzheimer disease mouse models. Compositions of NIC7 and NIC7w are suitable as a therapeutic agent in treating, preventing, or improving the conditions of Alzheimer's disease.
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13.发明公开公开(公告)号：US20240104756A1
公开(公告)日：2024-03-28
申请号：US18093887
申请日：2023-01-06
申请人： HYUNDAI MOTOR COMPANY , KIA CORPORATION , AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人： Jung Mo KOO , Kyoung Soo WE , Hye Yeon LEE , Gwang Jin KIM , Hyung Il KOO
摘要： An apparatus for measuring a depth of a tread groove may include: a camera module capturing a video including an upper end portion of a tire while rotating around an upper end portion of the tire having a plurality of tread grooves, the video including a plurality of frames; a control module obtaining, based on the plurality of frames, a cross-sectional width of the tire in units of pixels by adding widths and depths of each of the plurality of tread grooves in units of pixels, a width of an inner block in units of pixels, and a width of an outer block in units of pixels, the inner and outer blocks are disposed on the tire; and a conversion module converting the depth of the tread groove in units of pixels into the depth in units of pixels.
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公开(公告)号：US20240099620A1
公开(公告)日：2024-03-28
申请号：US18244044
申请日：2023-09-08
IPC分类号： A61B5/16 , G06F40/166 , G06F40/268 , G06F40/284
CPC分类号： A61B5/165 , G06F40/166 , G06F40/268 , G06F40/284
摘要： The present invention relates to a method and apparatus for checking mental health using contents, and may include collecting text data, which is content uploaded to at least one service server providing a social network service, by an electronic apparatus, performing preprocessing by which the electronic apparatus removes obsolete text from the text data and converts the extracted meaningful text to lowercase letters, performing, by the electronic apparatus, labeling of preprocessed meaningful text, performing, by the electronic apparatus, word embedding for the labeled meaningful text, and checking the mental health status of a user who has uploaded the text data by applying the word embedding result to a deep learning algorithm by the electronic apparatus, and it is possible to apply to other exemplary embodiments.
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公开(公告)号：US20240093243A1
公开(公告)日：2024-03-21
申请号：US18268894
申请日：2021-12-23
发明人： Sangdun CHOI , Javaid NASIR
CPC分类号： C12N15/907 , C07K14/47 , C12N9/22 , C12N15/111 , C12N2310/20 , C12N2800/80
摘要： A method for producing induced pluripotent stem cells by using CRISPR/Cas system is disclosed. The method includes a step of inserting a reprogramming factor by using a CRSPR/Cas system containing in a safe harbor of somatic cells a delivery means including two guides RNAs and a Cas protein-encoding nucleic acid. The method can prevent mutation in an off-target region and integrate a reprogramming factor into an on-target region safely and specifically, and regulates the reprogramming factor with doxycycline to guarantee consistent expression, whereby induced pluripotent stem cells can be effectively produced. In addition, the induced pluripotent stem cells produced by the method exhibit multipotent markers similar to those of human embryonic stem cells and can differentiate into derivatives of all the three germ layers.
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16.发明授权公开(公告)号：US11933881B2
公开(公告)日：2024-03-19
申请号：US17445661
申请日：2021-08-23
发明人： Jae Hyun Kim , Kyeongrok Kim
IPC分类号： G01S13/90
CPC分类号： G01S13/90
摘要： Disclosed are a method and apparatus for processing source data of a synthetic aperture radar in a satellite, including receiving source data generated based on a signal returned after an electronic device steers a beam from a synthetic aperture radar and backscatters, setting a plurality of subswaths after the electronic device parses the source data, storing based on the plurality of subswaths after the electronic device decodes the source data; and generating image data after the electronic device calls the decoded source data in the order of the plurality of subswaths.
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公开(公告)号：US20240034894A1
公开(公告)日：2024-02-01
申请号：US18265218
申请日：2021-11-02
发明人： Moon Suk KIM , Joon Yeong PARK
摘要： The present invention relates to a bio-ink composition for bio-printing comprising a polymer into which methacrylate is introduced, a crosslinking agent having 1-10 acrylate functional groups, and a photoinitiator; a method for preparing same; and a printing biological structure for controlling physical properties using same. The bio-ink composition for bio-printing prepared according to the present invention can be implanted in vivo and has a very high degree of biocompatibility or cell viability. In addition, the bio-ink composition of the present invention can be effectively utilized for bio-printing because a biological structure can be produced that is capable of controlling physical properties or in vivo application even when irradiated with light for a short period of time.
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18.发明授权公开(公告)号：US11881021B2
公开(公告)日：2024-01-23
申请号：US18187353
申请日：2023-03-21
发明人： Juyoung Kang , Sehyoung Kim , Seyeon Chun
CPC分类号： G06V20/188 , G06Q50/26
摘要： Provided are a method of providing carbon emission management information, the method comprising extracting, by a carbon emission management information providing server, an area corresponding to a company to be evaluated from satellite image data of the company to be evaluated, calculating, by the carbon emission management information providing server, a greenhouse gas concentration of the area corresponding to the company to be evaluated from the satellite image data, calculating, by the carbon emission management information providing server, a change in vegetation index around the company to be evaluated from the satellite image data, analyzing, by the carbon emission management information providing server, a relationship between carbon emission management factors input in relation to the company to be evaluated, a change in the calculated greenhouse gas concentration, and the calculated change in vegetation index and generating, by the carbon emission management information providing server, carbon emission management information by using both a relationship between the carbon emission management factors and the change in the calculated greenhouse gas concentration and a relationship between the carbon emission management factors and the calculated change in vegetation index according to a result of the analyzing, and providing the generated carbon emission management information.
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公开(公告)号：US20240000608A1
公开(公告)日：2024-01-04
申请号：US18039074
申请日：2021-11-16
发明人： Ji Man HONG
CPC分类号： A61F7/12 , F28F1/00 , A61F2007/006
摘要： The present invention provides a nasopharyngeal airway management device for brain-nasal cavity cooling according to the present invention including a cooling gas induction hose that is a tubular body with a hollow inside along a length, and induces a cooling gas introduced through one side to the other side; an adapter that is connected to the other side of the cooling gas induction hose, is mounted around the patient's upper lip, distributes the cooling gas induced through the cooling gas induction hose to a pair of discharge ripples, and discharges the cooling gas; and a nasal cavity cooling tube that is a tubular body with a hollow inside along a length, one side is coupled to a discharge nipple of the adapter and the other side of which is inserted into the patient's nasal cavity, and forms a plurality of discharge holes for discharging the cooling gas to any one point of the length, so that the nasal cavity cooling tube that is connected to the adapter fixed to the patient's upper lip, and dividing and discharging the cooling gas introduced through the cooling gas induction hose is inserted into the nasopharynx through the patient's nostril, and the cooling gas (low-temperature oxygen) discharged through the discharge hole of the the nasal cavity cooling tube is discharged into the nasal cavity close to the brain, and thereby quick and easy stable local cooling of the brain is induced while maintaining the nasopharyngeal airway.
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公开(公告)号：US20230406295A1
公开(公告)日：2023-12-21
申请号：US18333840
申请日：2023-06-13
申请人： Hyundai Motor Company , Kia Corporation , Ajou University Industry-Academic Cooperation Foundation
发明人： Chan Jong Jang , Young Bin Min , Cheol Hwan Yun , Jong Sung Park , Bong Sob Song , Ji Min Lee , Sung Woo Lee
IPC分类号： B60W30/09 , B60W30/095 , B60W60/00
CPC分类号： B60W30/09 , B60W30/0956 , B60W60/0015 , B60W2554/4041
摘要： An embodiment method for operating a vehicle includes monitoring a state of the vehicle, determining a type of an emergency stop from a plurality of types of emergency stops based on the state of the vehicle, and executing the determined type of the emergency stop. An embodiment vehicle includes sensors, a processor configured to control automated driving of the vehicle based on state information of components of the vehicle and surrounding environment information of the vehicle detected by the sensors, and a controller configured to control an operation of the vehicle based on a control of the processor, wherein the processor is further configured to monitor a state of the vehicle, determine a type of an emergency stop from a plurality of types of emergency stops based on the state of the vehicle, and execute the determined type of the emergency stop by controlling the controller.
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