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    User interface with toolbar for programming electrical stimulation therapy
    11.
    发明授权
    User interface with toolbar for programming electrical stimulation therapy 有权
    用户界面，用于编程电刺激治疗工具栏

    公开(公告)号：US08255060B2

    公开(公告)日：2012-08-28

    申请号：US11999735

    申请日：2007-12-06

    申请人： Steven M. Goetz ,  Jeffrey T. Keacher ,  Rajeev Sahasrabudhe ,  Wende L. Dewing ,  Jon P. Davis ,  John Rondoni ,  Gabriela C. Miyazawa ,  Gary W. King

    发明人： Steven M. Goetz ,  Jeffrey T. Keacher ,  Rajeev Sahasrabudhe ,  Wende L. Dewing ,  Jon P. Davis ,  John Rondoni ,  Gabriela C. Miyazawa ,  Gary W. King

    IPC分类号： A61N1/372

    CPC分类号： A61N1/37247 ,  A61N1/36185

    摘要： The disclosure is directed to a user interface with a menu that facilitates stimulation therapy programming. The user interface displays a representation of the electrical leads implanted in the patient and at least one menu with icons that the user can use to adjust the stimulation therapy. The user may drag one or more field shapes from a field shape selection menu onto the desired location relative to the electrical leads. A manipulation tool menu may also allow the user to adjust the field shapes placed on the electrical leads, which represent the stimulation region. The programmer that includes the user interface then generates electrical stimulation parameter values for the stimulator to deliver stimulation according to the field shapes or field shape groups defined/located by the user. The field shapes may represent different types of stimulation representations, such as current density, activation functions, and neuron models.

    摘要翻译： 本公开针对具有促进刺激治疗编程的菜单的用户界面。 用户界面显示植入患者中的电引线的表示以及具有用户可用于调整刺激疗法的图标的至少一个菜单。 用户可以将一个或多个场形状从场形选择菜单拖到相对于电引线的期望位置上。 操作工具菜单还可以允许用户调整放置在电引线上的场形状，其代表刺激区域。 包括用户界面的程序员然后产生刺激器的电刺激参数值，以根据由用户定义/定位的场形状或场形组递送刺激。 场形状可以表示不同类型的刺激表示，例如电流密度，激活函数和神经元模型。

    STIMULATION FIELD MANAGEMENT
    12.
    发明申请
    STIMULATION FIELD MANAGEMENT 审中-公开
    刺激现场管理

    公开(公告)号：US20090054941A1

    公开(公告)日：2009-02-26

    申请号：US12195313

    申请日：2008-08-20

    申请人： Michael D. Eggen ,  John L. Sommer ,  Michael Ebert ,  David Wayne Bourn ,  Gabriela C. Miyazawa

    发明人： Michael D. Eggen ,  John L. Sommer ,  Michael Ebert ,  David Wayne Bourn ,  Gabriela C. Miyazawa

    IPC分类号： A61N1/05 ,  A61N1/362

    CPC分类号： A61N1/0565 ,  A61N2001/0585

    摘要： This disclosure describes techniques for controlling a depth of propagation of a stimulation field extending from an outer diameter of a lead body of an implantable stimulation lead. An implantable electrical stimulation lead may include a lead body, and at least one electrode arranged as a ring. An outer diameter of the ring may be different than an outer diameter of the lead body. A ring with a diameter smaller than the diameter of the lead body may be useful in limiting the depth of propagation of the stimulation field within patient tissue. A ring with a diameter greater than the diameter of the lead body may be useful in extending the depth of propagation of the stimulation field.

    摘要翻译： 本公开描述了用于控制从可植入刺激引线的引线体的外径延伸的刺激场的传播深度的技术。 可植入电刺激引线可以包括引线体，以及布置成环的至少一个电极。 环的外径可以与引线体的外径不同。 直径小于引线主体直径的环可用于限制刺激场在患者组织内的传播深度。 具有大于引线主体直径的直径的环可以用于延长刺激场的传播深度。

    IMPLANTABLE MEDICAL LEAD WITH MULTIPLE ELECTRODE CONFIGURATIONS
    13.
    发明申请
    IMPLANTABLE MEDICAL LEAD WITH MULTIPLE ELECTRODE CONFIGURATIONS 有权
    具有多个电极配置的可植入医疗引线

    公开(公告)号：US20080269854A1

    公开(公告)日：2008-10-30

    申请号：US11740643

    申请日：2007-04-26

    申请人： Michael T. Hegland ,  James M. Olsen ,  Gabriela C. Miyazawa ,  Richard T. Stone

    发明人： Michael T. Hegland ,  James M. Olsen ,  Gabriela C. Miyazawa ,  Richard T. Stone

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0534 ,  A61N1/36082

    摘要： Medical leads having at least one segmented row of electrodes, as well as at least one ring electrode that extends substantially completely around the periphery of the lead, are described. The electrodes in a segmented row extend around only a portion of the periphery of the lead, rather than substantially around the entire periphery. The electrodes in a segmented row may be distributed at respective locations around the periphery of the lead and separated by insulating material. The ring electrodes and segmented rows are located at respective axial positions. For example, in some embodiments, a plurality of segmented rows, such as two rows having three electrodes each, are located between two ring electrodes. Such a lead may, for example, provide a variety of stimulation modalities because of localized stimulation capabilities.

    摘要翻译： 描述了具有至少一个分段的电极列的医疗引线以及基本上完全围绕引线的周边延伸的至少一个环形电极。 分段行中的电极仅围绕引线周边的一部分延伸，而不是基本上围绕整个周边延伸。 分段行中的电极可以分布在引线的周围的相应位置处并被绝缘材料隔开。 环形电极和分段行位于相应的轴向位置。 例如，在一些实施例中，多个分段行（例如具有三个电极的两行）分布在两个环形电极之间。 例如，这样的引线可以由于局部刺激能力而提供各种刺激模式。

    User interface with toolbar for programming electrical stimulation therapy
    15.
    发明授权
    User interface with toolbar for programming electrical stimulation therapy 有权
    用户界面，用于编程电刺激治疗工具栏

    公开(公告)号：US08798759B2

    公开(公告)日：2014-08-05

    申请号：US11999722

    申请日：2007-12-06

    申请人： Steven M. Goetz ,  Jeffrey T. Keacher ,  Rajeev Sahasrabudhe ,  Wende L. Dewing ,  Jon P. Davis ,  John Rondoni ,  Gabriela C. Miyazawa ,  Gary W. King

    发明人： Steven M. Goetz ,  Jeffrey T. Keacher ,  Rajeev Sahasrabudhe ,  Wende L. Dewing ,  Jon P. Davis ,  John Rondoni ,  Gabriela C. Miyazawa ,  Gary W. King

    IPC分类号： A61N1/00

    CPC分类号： A61N1/37247 ,  A61N1/36185

    摘要： The disclosure is directed to a user interface with a menu that facilitates stimulation therapy programming. The user interface displays a representation of the electrical leads implanted in the patient and at least one menu with icons that the user can use to adjust the stimulation therapy. The user may drag one or more field shapes from a field shape selection menu onto the desired location relative to the electrical leads. A manipulation tool menu may also allow the user to adjust the field shapes placed on the electrical leads, which represent the stimulation region. The programmer that includes the user interface then generates electrical stimulation parameter values for the stimulator to deliver stimulation according to the field shapes or field shape groups defined/located by the user. The field shapes may represent different types of stimulation representations, such as current density, activation functions, and neuron models.

    摘要翻译： 本公开针对具有促进刺激治疗编程的菜单的用户界面。 用户界面显示植入患者中的电引线的表示以及具有用户可用于调整刺激疗法的图标的至少一个菜单。 用户可以将一个或多个场形状从场形选择菜单拖到相对于电引线的期望位置上。 操作工具菜单还可以允许用户调整放置在电引线上的场形状，其代表刺激区域。 包括用户界面的程序员然后产生刺激器的电刺激参数值，以根据由用户定义/定位的场形状或场形组递送刺激。 场形状可以表示不同类型的刺激表示，例如电流密度，激活函数和神经元模型。

    Evaluating therapeutic stimulation electrode configurations based on physiological responses
    17.
    发明授权
    Evaluating therapeutic stimulation electrode configurations based on physiological responses 有权
    基于生理反应评价治疗性刺激电极结构

    公开(公告)号：US08326418B2

    公开(公告)日：2012-12-04

    申请号：US12195317

    申请日：2008-08-20

    申请人： John L. Sommer ,  David Wayne Bourn ,  Mark T. Marshall ,  Michael D. Eggen ,  Gabriela C. Miyazawa

    发明人： John L. Sommer ,  David Wayne Bourn ,  Mark T. Marshall ,  Michael D. Eggen ,  Gabriela C. Miyazawa

    IPC分类号： A61N1/05

    CPC分类号： A61N1/36514 ,  A61N1/056 ,  A61N1/36114 ,  A61N1/36185 ,  A61N1/3684 ,  A61N1/3686 ,  A61N2001/0585

    摘要： A medical system comprises a plurality of electrodes; at least one sensor configured to output at least one signal based on at least one physiological parameter of a patient; and a processor. The processor is configured to control delivery of stimulation to the patient using a plurality of electrode configurations. Each of the electrode configurations comprises at least one of the plurality of electrodes. For each of the electrode configurations, the processor is configured to determine a first response of target tissue to the stimulation based on the signals, and a second response of non-target tissue to the stimulation based on the signals. The processor is also configured to select at least one of the electrode configurations for delivery of stimulation to the patient based on the first and second responses for the electrode configurations. As examples, the target tissue may be a left ventricle or vagus nerve.

    摘要翻译： 医疗系统包括多个电极; 至少一个传感器被配置为基于患者的至少一个生理参数输出至少一个信号; 和处理器。 处理器被配置为使用多个电极配置来控制对患者的刺激递送。 每个电极配置包括多个电极中的至少一个。 对于每个电极配置，处理器被配置为基于信号来确定目标组织对刺激的第一响应，以及基于该信号来确定非目标组织对刺激的第二响应。 处理器还被配置为基于电极配置的第一和第二响应来选择用于将刺激递送到患者的电极配置中的至少一个。 作为示例，靶组织可以是左心室或迷走神经。

    MEDICAL DEVICE CONFIGURATION BASED ON SENSED BRAIN SIGNALS
    18.
    发明申请
    MEDICAL DEVICE CONFIGURATION BASED ON SENSED BRAIN SIGNALS 有权
    基于感觉脑信号的医疗设备配置

    公开(公告)号：US20110251583A1

    公开(公告)日：2011-10-13

    申请号：US13167754

    申请日：2011-06-24

    申请人： Gabriela C. Miyazawa ,  Gregory F. Molnar

    发明人： Gabriela C. Miyazawa ,  Gregory F. Molnar

    IPC分类号： A61N1/36 ,  A61M5/168

    CPC分类号： A61N1/36071 ,  A61B5/048 ,  A61B5/7257

    摘要： The invention is directed to techniques and systems in which external brain monitoring is used to facilitate implantation and configuration of an implantable medical device. The techniques may create an open loop or closed loop system in which brain signals quantify the efficacy of electrical logical stimulation (or drug therapy via an implantable drug pump) at locations outside of the brain. The techniques may be used to improve placement of leads and electrodes during an implantation procedure, and/or to select or adjust stimulation parameters either during the implantation procedure or possibly following implantation of an implantable medical device. The described techniques have applications for the alleviation of pain, but may find other applications where EEG signals can quantify the efficacy of treatment via an implantable medical device.

    摘要翻译： 本发明涉及使用外部脑部监测来促进可植入医疗装置的植入和构造的技术和系统。 这些技术可以产生开环或闭环系统，其中脑信号定量在脑外部位置的电逻辑刺激（或通过可植入药物泵的药物治疗）的功效。 这些技术可以用于在植入过程期间改善引线和电极的放置，和/或在植入过程期间或可能在植入可植入医疗器械之后选择或调整刺激参数。 所描述的技术具有减轻疼痛的应用，但是可以找到其他应用，其中EEG信号可以通过可植入医疗装置量化治疗的功效。

    Selecting electrode combinations for stimulation therapy
    20.
    发明授权
    Selecting electrode combinations for stimulation therapy 有权
    选择电极组合进行刺激治疗

    公开(公告)号：US08620452B2

    公开(公告)日：2013-12-31

    申请号：US11810943

    申请日：2007-06-07

    申请人： Gary W. King ,  Gabriela C. Miyazawa ,  Jordan J. Greenberg ,  Steven M. Goetz

    发明人： Gary W. King ,  Gabriela C. Miyazawa ,  Jordan J. Greenberg ,  Steven M. Goetz

    IPC分类号： A61N1/05

    CPC分类号： A61N1/37247 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/0553 ,  A61N1/36185 ,  G06F19/00 ,  G06F19/3481 ,  G16H40/63

    摘要： Techniques for selecting electrode combinations for stimulation therapy include delivering stimulation via each of at least five combination groups. A first group of electrode combinations is characterized by the presence of a caudal anode. A second group of electrode combinations is characterized by the presence of a rostral anode. A third group of electrode combinations is characterized by the presence of a single anode above and a single anode below the cathode(s) of the combination. A fourth group of electrode combinations is characterized by the presence of multiple anodes above and below the cathode(s) of the combination. A fifth group of electrode combinations is characterized by the presence of transverse anodes. A sixth group of electrode combination is characterized by at least one off-center cathode. One or more preferred electrode combinations groups, and/or a number of leads to implant within the patient, may by selected based on patient feedback.

    摘要翻译： 用于选择用于刺激治疗的电极组合的技术包括通过至少五个组合组中的每一个递送刺激。 第一组电极组合的特征在于尾部阳极的存在。 第二组电极组合的特征在于存在罗氏阳极。 第三组电极组合的特征在于在组合的阴极下方存在单个阳极和单个阳极。 第四组电极组合的特征在于在组合的阴极上方和下方存在多个阳极。 第五组电极组合的特征在于存在横向阳极。 第六组电极组合的特征在于至少一个偏心阴极。 可以通过基于患者反馈来选择一个或多个优选的电极组合组和/或在患者体内植入的多个引线。