公开(公告)号：US06306165B1

公开(公告)日：2001-10-23

申请号：US08713800

申请日：1996-09-13

Applicant: Birendra K. Patnaik ,  Horng-Ban Lin ,  David J. Lentz ,  Richard J. Zdrahala

Inventor： Birendra K. Patnaik ,  Horng-Ban Lin ,  David J. Lentz ,  Richard J. Zdrahala

IPC: A61F206

CPC classification number: A61L27/34 ,  A61L27/507 ,  A61L33/0029 ,  A61L33/0047 ,  A61L33/0094

Abstract: Disclosed are implantable medical devices with enhanced patency. Expanded polytetrafluoroethylene small caliber vascular grafts coated with polymer bound bio-active agents that exhibit enhanced patency are disclosed. The polymer bound bio-active agents can include anti-thrombogenic agents, antibiotics, antibacterial agents and antiviral agents. Methods of preparing same are also provided.

Abstract translation: 公开了具有增强的通畅的可植入医疗装置。 公开了扩张聚四氟乙烯小口径血管移植物，其涂覆有聚合物结合的生物活性剂，其显示增强的通畅。 聚合物结合的生物活性剂可以包括抗血栓形成剂，抗生素，抗菌剂和抗病毒剂。 还提供了制备方法。

公开(公告)号：US5556426A

公开(公告)日：1996-09-17

申请号：US284904

申请日：1994-08-02

Applicant: Nicholas Popadiuk ,  Horng-Ban Lin ,  Richard J. Zdrahala

Inventor： Nicholas Popadiuk ,  Horng-Ban Lin ,  Richard J. Zdrahala

IPC: A61L27/00 ,  A61F2/06 ,  A61F2/04

CPC classification number: A61F2/06

Abstract: A flexible implantable luminal device is disclosed, which is made from a porous cylindrical tube manufactured from extruded fluoropolymer. A fluoropolymer filament is wrapped helically around the external surface of the tube. The filament is fused to the tube to form a unitary composite structure by heating the wrapped tube to a temperature above the melting points of the fluoropolymers. The resulting composite is a radially reinforced flexible luminal prosthesis suitable for implantation, particularly, as a vascular graft or endoprosthesis. Also disclosed is a method for manufacturing the prosthesis.

Abstract translation: 公开了一种柔性可植入管腔装置，其由由挤出的含氟聚合物制成的多孔圆筒管制成。 含氟聚合物长丝围绕管的外表面螺旋缠绕。 通过将包裹的管加热到高于含氟聚合物的熔点的温度，将细丝熔合到管上以形成整体复合结构。 所得到的复合物是适于植入的径向增强的柔性管腔假体，特别是作为血管移植物或内用假体。 还公开了一种用于制造假体的方法。

公开(公告)号：US20140005772A1

公开(公告)日：2014-01-02

申请号：US13932968

申请日：2013-07-01

Applicant: Peter Edelman ,  Horng-Ban Lin ,  Scott Fisher ,  Jeffrey S. Lindquist ,  Huisun Wang ,  Richard C. Gunderson

Inventor： Peter Edelman ,  Horng-Ban Lin ,  Scott Fisher ,  Jeffrey S. Lindquist ,  Huisun Wang ,  Richard C. Gunderson

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/24 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2210/0076 ,  A61F2250/0014 ,  A61F2250/0018 ,  A61F2250/0028 ,  A61F2250/0036 ,  A61F2250/0037 ,  A61L27/18 ,  A61L27/34 ,  A61L2430/20 ,  B05B7/0408 ,  B05B7/0416 ,  B05B7/0433 ,  B05B7/0466 ,  B05B12/00 ,  B05B12/1454 ,  B05B13/0207 ,  B05B13/0627 ,  B05D1/02 ,  B05D7/222 ,  B05D2254/02 ,  B33Y80/00 ,  Y10T29/49405 ,  C08L75/04 ,  C08L83/04

Abstract: A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets. Each leaflet includes) at least two polymers along at least one portion of the leaflet, and each leaflet has a composition gradient of each of the at least two polymers along at least one portion of the leaflet.

Abstract translation: 假体心脏瓣膜包括基部和多个聚合单张。 每个小叶具有连接到基部的根部分，并且每个小叶具有基本上与根部相对的边缘部分，并且相对于根部部分可移动以与多个传单中的至少一个其他传单中的至少一个的相应边缘部分配合 。 每个小叶包括）沿着小叶的至少一部分的至少两种聚合物，并且每个小叶具有沿着小叶的至少一部分的每种至少两种聚合物的组成梯度。

公开(公告)号：US20110118628A1

公开(公告)日：2011-05-19

申请号：US12620343

申请日：2009-11-17

Applicant: PU ZHOU ,  HORNG-BAN LIN ,  HANCUN CHEN ,  JAMES FENG

Inventor： PU ZHOU ,  HORNG-BAN LIN ,  HANCUN CHEN ,  JAMES FENG

IPC: A61M25/09

CPC classification number: A61M25/09 ,  A61M2025/09083 ,  A61M2025/09133

Abstract: Medical devices and methods for making and using the same. An example medical device may include a guidewire. The guidewire may include an elongate shaft. The shaft may include a porous metal alloy. The porous metal alloy may be arranged so that the porous metal alloy has a first pore distribution along a first portion of the shaft and a second pore distribution different from the first pore distribution along a second portion of the shaft.

Abstract translation: 医疗器械及其制造和使用方法。 示例性医疗设备可以包括导丝。 导丝可以包括细长轴。 轴可以包括多孔金属合金。 多孔金属合金可以布置成使得多孔金属合金沿着轴的第一部分具有第一孔分布，并且沿着轴的第二部分具有不同于第一孔分布的第二孔分布。

公开(公告)号：US07875051B2

公开(公告)日：2011-01-25

申请号：US11556017

申请日：2006-11-02

Applicant: Mel R. Beulke ,  Horng-Ban Lin ,  Gary R. Kostur

Inventor： Mel R. Beulke ,  Horng-Ban Lin ,  Gary R. Kostur

IPC: A61M29/00

CPC classification number: A61F2/013 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/008

Abstract: An embolic protection filter having an improved filter frame and method of making the same. In at least some embodiments, the present invention includes an embolic protection filter coupled to an elongate shaft. The filter may include a filter frame assembly having one or more frame members. The frame members may include a filter mouth defining portion.

Abstract translation: 一种具有改进的过滤器框架的栓塞保护过滤器及其制造方法。 在至少一些实施例中，本发明包括联接到细长轴的栓塞保护过滤器。 过滤器可以包括具有一个或多个框架构件的过滤器框架组件。 框架构件可以包括过滤嘴限定部分。

公开(公告)号：US20100207291A1

公开(公告)日：2010-08-19

申请号：US12370724

申请日：2009-02-13

Applicant: Tracee Eidenschink ,  James Feng ,  Karl A. Jagger ,  Daniel Gregorich ,  Leonard B. Richardson ,  Timothy J. Mickley ,  James Lee Shippy ,  Daniel J. Horn ,  John J. Chen ,  Thomas J. Holman ,  David McMorrow ,  Jon Kolbrek ,  Horng-Ban Lin

Inventor： Tracee Eidenschink ,  James Feng ,  Karl A. Jagger ,  Daniel Gregorich ,  Leonard B. Richardson ,  Timothy J. Mickley ,  James Lee Shippy ,  Daniel J. Horn ,  John J. Chen ,  Thomas J. Holman ,  David McMorrow ,  Jon Kolbrek ,  Horng-Ban Lin

IPC: B29D23/00 ,  B21C23/08

CPC classification number: B29C48/05 ,  A61M25/0009 ,  B29C48/0022 ,  B29C48/09 ,  B29C48/11 ,  B29C48/151 ,  B29L2031/7542

Abstract: A method of producing a tubular member which includes providing at least one micro-extruder configured to extrude at least one material and providing a surface configured to accept the material extruded from the micro-extruder.

Abstract translation: 一种制造管状构件的方法，其包括提供至少一个微型挤出机，所述微型挤出机构造成挤出至少一种材料并提供构造成接受从微型挤出机挤出的材料的表面。

公开(公告)号：US20080051671A1

公开(公告)日：2008-02-28

申请号：US11929007

申请日：2007-10-30

Applicant: Thomas Broome ,  Anthony Vrba ,  Narin Anderson ,  Justin Crank ,  James Hansen ,  Horng-Ban Lin ,  Mark Smith

Inventor： Thomas Broome ,  Anthony Vrba ,  Narin Anderson ,  Justin Crank ,  James Hansen ,  Horng-Ban Lin ,  Mark Smith

IPC: A61B5/026

CPC classification number: A61B5/02158 ,  A61B5/02156 ,  A61F2/013

Abstract: Devices and methods for monitoring the flow of blood through an intravascular device are disclosed. An apparatus for monitoring blood flow in accordance with an exemplary embodiment of the present invention includes an intravascular device coupled to an elongated member, a first sensor adapted to measure fluidic pressure proximal the intravascular device, a second sensor adapted to measure fluidic pressure distal the intravascular device, and a control unit for comparing the signals received from the first and second sensors to determine the pressure drop across the intravascular device.

Abstract translation: 公开了通过血管内装置监测血流的装置和方法。 根据本发明的示例性实施例的用于监测血流的装置包括联接到细长构件的血管内装置，适于测量血管内装置近侧的流体压力的第一传感器，适于测量血管内远端的流体压力的第二传感器 装置和控制单元，用于比较从第一和第二传感器接收的信号，以确定穿过血管内装置的压降。

公开(公告)号：US20070014945A1

公开(公告)日：2007-01-18

申请号：US11179290

申请日：2005-07-12

Applicant: Horng-Ban Lin ,  James Hansen

Inventor： Horng-Ban Lin ,  James Hansen

IPC: B32B1/08

CPC classification number: A61M25/09 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/10 ,  A61M25/0009 ,  A61M25/0045 ,  A61M2025/0046 ,  A61M2025/09108 ,  A61M2025/09133 ,  A61M2025/09175 ,  B32B1/08 ,  B32B27/08 ,  B32B27/40 ,  B32B2250/24 ,  B32B2255/10 ,  B32B2307/746 ,  B32B2535/00 ,  Y10T428/13 ,  C08L75/04

Abstract: Medical devices and methods for manufacturing the same. An example medical device includes a shaft or substrate that is coated with a lubricious coating. The coating includes a plurality of sections that have differing lubricities. At least some of the sections include a hydrophilic polyurethane. A coated section can include an aliphatic polyether polyurethane. The methods for manufacturing the medical devices may include at least in part microdispensing such as inkjet-type printing.

Abstract translation: 医疗器械及其制造方法。 示例性的医疗装置包括涂覆有润滑涂层的轴或基底。 涂层包括具有不同润滑性的多个部分。 至少一些部分包括亲水性聚氨酯。 涂覆部分可以包括脂族聚醚聚氨酯。 用于制造医疗装置的方法可以至少部分地包括诸如喷墨型印刷的微分配。

公开(公告)号：US20050251198A1

公开(公告)日：2005-11-10

申请号：US10841684

申请日：2004-05-06

Applicant: Mark Smith ,  James Hansen ,  Justin Crank ,  Narin Anderson ,  Horng-Ban Lin

Inventor： Mark Smith ,  James Hansen ,  Justin Crank ,  Narin Anderson ,  Horng-Ban Lin

IPC: A61F2/01 ,  B01D63/00 ,  B01D67/00 ,  B01D69/00 ,  A61M29/00

CPC classification number: B01D69/00 ,  A61F2/01 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/008 ,  B01D63/00 ,  B01D67/002 ,  B01D69/10 ,  B01D2323/24

Abstract: Intravascular filters formed by a molding process can have a plurality of integrally formed apertures. A molding process can utilize a mold assembly that includes a mold having a mold surface and a die having a die surface. The mold assembly includes plurality of protrusions that extend from at least one of the mold surface and the die surface. A molten material is placed within a portion of the mold, and the die is then inserted into the mold such that the plurality of protrusions span a distance between the die surface and the mold surface. The molten material is allowed to solidify, thereby forming a filter membrane that includes a plurality of integrally formed apertures.

Abstract translation: 通过模制工艺形成的血管内过滤器可以具有多个一体形成的孔。 模制工艺可以利用包括具有模具表面的模具和具有模具表面的模具的模具组件。 模具组件包括从模具表面和模具表面中的至少一个延伸的多个突起。 将熔融材料放置在模具的一部分内，然后将模具插入模具中，使得多个突起跨过模具表面和模具表面之间的距离。 允许熔融材料固化，从而形成包括多个一体形成的孔的过滤膜。