Isolation and purification method of biomolecules using hydrogel
    11.
    发明授权
    Isolation and purification method of biomolecules using hydrogel 有权
    使用水凝胶分离和纯化生物分子的方法

    公开(公告)号:US07579151B2

    公开(公告)日:2009-08-25

    申请号:US11191221

    申请日:2005-07-27

    IPC分类号: C12Q1/68 C07H21/00

    CPC分类号: C12N15/1006

    摘要: Provided is a method of isolating and purifying biomolecules using a hydrogel, the method including: bring a sample containing charged biomolecules into contact with a hydrogel to bind the biomolecules to the hydrogel; washing the hydrogel bound with the biomolecules; and eluting the bound biomolecules using an elution solvent. According to the method, the use of a hydrogel with a large surface area reduces the isolation time of biomolecules to 5 min or less, an external device such as an electromagnet is not required, and small-sized systems or LOC can be easily implemented due to applicability to microsystems through a polymer patterning technique.

    摘要翻译: 提供了使用水凝胶分离和纯化生物分子的方法,该方法包括:使含有带电生物分子的样品与水凝胶接触以将生物分子结合至水凝胶; 洗涤与生物分子结合的水凝胶; 并使用洗脱溶剂洗脱结合的生物分子。 根据该方法,使用具有大表面积的水凝胶将生物分子的隔离时间减少到5分钟以下,不需要诸如电磁体的外部装置,并且可以容易地实现小尺寸系统或LOC 通过聚合物图案化技术适用于微系统。

    MICROVALVE HAVING MAGNETIC WAX PLUG AND FLUX CONTROL METHOD USING MAGNETIC WAX
    12.
    发明申请
    MICROVALVE HAVING MAGNETIC WAX PLUG AND FLUX CONTROL METHOD USING MAGNETIC WAX 有权
    具有磁性波纹管的微型光栅和使用磁性WAX的通量控制方法

    公开(公告)号:US20090071542A1

    公开(公告)日:2009-03-19

    申请号:US12277780

    申请日:2008-11-25

    IPC分类号: F17D1/16

    摘要: Provided is a microvalve having a magnetic wax plug which includes a micro fluidic structure having an inlet portion and an outlet portion, a magnetic wax plug provided at a predetermined section where the inlet portion and the outlet portion meet, existing in a solid state, melted at a temperature higher than a predetermined temperature, and reversibly moving along a magnetic field, so as to control flux of a fluid through the micro fluidic structure, a heating portion provided corresponding to the section and heating the magnetic wax plug to be melted, and a magnetic field application portion selectively applying a magnetic field to a position where the melted magnetic wax plug arrives.

    摘要翻译: 提供一种具有磁性蜡塞的微型阀,其包括具有入口部分和出口部分的微流体结构,设置在入口部分和出口部分相遇的预定部分处的固体状态的熔融蜡 在高于预定温度的温度下,并且沿着磁场可逆地移动,以便控制通过微流体结构的流体的通量;对应于该部分设置的加热部分,并加热待熔化的磁性蜡塞;以及 选择性地将磁场施加到熔融的磁性蜡塞到达的位置的磁场施加部。

    Valve
    13.
    发明授权
    Valve 有权

    公开(公告)号:US07424995B2

    公开(公告)日:2008-09-16

    申请号:US11327236

    申请日:2006-01-05

    IPC分类号: F16K31/02

    CPC分类号: F16K31/0679 Y10T137/87788

    摘要: A valve is provided. The valve includes a plunger, a chamber having a first region and a second region where the plunger moves back and forth, a first electromagnet and a second electromagnet which are located around the first region and the second region to apply a magnetic field to the plunger, a fluid inlet through which a fluid enters into the chamber, located between the first region and the second region of the chamber, and a second fluid outlet located on a vertical end part of the second region away from the first region.

    摘要翻译: 提供阀门。 阀包括柱塞,具有第一区域和柱塞前后移动的第二区域的腔室,位于第一区域和第二区域周围的第一电磁体和第二电磁体,以向柱塞施加磁场 ,流体入口,流体通过所述流体入口位于所述室的所述第一区域和所述第二区域之间,以及位于所述第二区域的远离所述第一区域的垂直端部的第二流体出口。

    Optical system for analyzing multi-channel samples and multi-channel sample analyzer employing the same
    14.
    发明授权
    Optical system for analyzing multi-channel samples and multi-channel sample analyzer employing the same 有权
    用于分析多通道样品的光学系统和采用该多通道样品的多通道样品分析仪

    公开(公告)号:US07209237B2

    公开(公告)日:2007-04-24

    申请号:US11227385

    申请日:2005-09-15

    IPC分类号: G01N21/25

    CPC分类号: G01N21/645

    摘要: Provided are an optical system for analyzing multi-channel samples which uses a mirror rotating at high speeds and an aspherical mirror, and a multi-channel sample analyzer employing the optical system. The optical system for analyzing multi-channel samples, includes a light source unit which emits light traveling along an optical axis; a semi-spheroid aspherical mirror disposed in rotational symmetry about the optical axis; and an inclined mirror which reflects the light exiting the light source unit to the semi-spheroid aspherical mirror, while rotating about the optical axis, wherein an opening is formed in the center of the semi-spheroid aspherical mirror such that the light exiting the light source unit enters the inclined mirror through the semi-spheroid aspherical mirror.

    摘要翻译: 提供了一种用于分析使用高速旋转的反射镜的多通道样品和非球面镜的光学系统,以及采用该光学系统的多通道样本分析仪。 用于分析多通道样品的光学系统包括发射沿着光轴行进的光的光源单元; 围绕光轴旋转对称设置的半球体非球面镜; 以及倾斜镜,其在围绕光轴旋转的同时将离开光源单元的光反射到半球形非球面镜,其中在半球镜非球面镜的中心形成开口,使得离开光的光 源单元通过半球体非球面镜进入倾斜镜。

    Microvalve device and apparatus adopting the same
    15.
    发明申请
    Microvalve device and apparatus adopting the same 审中-公开
    微阀装置及其采用的装置

    公开(公告)号:US20060169339A1

    公开(公告)日:2006-08-03

    申请号:US11346452

    申请日:2006-02-02

    IPC分类号: F15C1/04

    摘要: A microvalve device is provided. The microvalve device uses electrolysis and uses a hydrogel swelling and deswelling in response to anions or cations as an actuator for controlling the path of a flowing fluid. The microvalve device does not require a buffer solution but uses the transfer fluid flowing in a valve as a source driving the actuator. To generate the anions or cations, an electrode is needed for electrolysis of the fluid near the hydrogel. The microvalve is easy to manufacture and has a simple structure. In addition, the micro valve is useful to manufacture fluid channel arrays having various multi-channel structures.

    摘要翻译: 提供微型阀装置。 微阀装置使用电解,并且响应于阴离子或阳离子作为用于控制流动流体的路径的致动器,使用水凝胶溶胀和溶解。 微阀装置不需要缓冲溶液,而是使用流过阀的转移流体作为驱动致动器的源。 为了产生阴离子或阳离子,需要电极来电解水凝胶附近的流体。 微型阀门易于制造,结构简单。 此外,微阀可用于制造具有各种多通道结构的流体通道阵列。

    Microvalve having magnetic wax plug and flux control method using magnetic wax
    16.
    发明授权
    Microvalve having magnetic wax plug and flux control method using magnetic wax 有权
    具有磁性蜡塞的微型阀和使用磁性蜡的助焊剂控制方法

    公开(公告)号:US07874305B2

    公开(公告)日:2011-01-25

    申请号:US12277780

    申请日:2008-11-25

    IPC分类号: F17D1/16 F17D1/18

    摘要: Provided is a microvalve having a magnetic wax plug which includes a micro fluidic structure having an inlet portion and an outlet portion, a magnetic wax plug provided at a predetermined section where the inlet portion and the outlet portion meet, existing in a solid state, melted at a temperature higher than a predetermined temperature, and reversibly moving along a magnetic field, so as to control flux of a fluid through the micro fluidic structure, a heating portion provided corresponding to the section and heating the magnetic wax plug to be melted, and a magnetic field application portion selectively applying a magnetic field to a position where the melted magnetic wax plug arrives.

    摘要翻译: 提供一种具有磁性蜡塞的微型阀,其包括具有入口部分和出口部分的微流体结构,设置在入口部分和出口部分相遇的预定部分处的固体状态的熔融蜡 在高于预定温度的温度下,并且沿着磁场可逆地移动,以便控制通过微流体结构的流体的通量;对应于该部分设置的加热部分,并加热待熔化的磁性蜡塞;以及 选择性地将磁场施加到熔融的磁性蜡塞到达的位置的磁场施加部。

    Handheld centrifuge
    18.
    发明授权
    Handheld centrifuge 有权
    手持离心机

    公开(公告)号:US07645223B2

    公开(公告)日:2010-01-12

    申请号:US11333857

    申请日:2006-01-17

    IPC分类号: B04B5/02 B04B9/00

    摘要: A handheld centrifuge includes an inertia body having an axle and a pair of inertia wheels coupled to the axle. The inertia wheels are coupled to the axle in substantially perpendicular direction to the axle, and spaced apart from each other. A string is connected to the axle. At least one closed vessel is detachably installed on an outer face of the inertia wheel to contain a substance to be centrifuged. The closed vessel is installed in substantially radial direction of the inertia wheel.

    摘要翻译: 手持式离心机包括惯性体,其具有轴和耦合到该轴的一对惯性轮。 惯性轮以基本上垂直于轴的方向联接到车轴并且彼此间隔开。 一根绳子连接到轴上。 至少一个密封容器可拆卸地安装在惯性轮的外表面上以容纳待离心的物质。 密闭容器沿惯性轮的大致径向安装。

    Microvalve having magnetic wax plug and flux control method using magnetic wax
    19.
    发明授权
    Microvalve having magnetic wax plug and flux control method using magnetic wax 有权
    具有磁性蜡塞的微型阀和使用磁性蜡的助焊剂控制方法

    公开(公告)号:US07478792B2

    公开(公告)日:2009-01-20

    申请号:US11396764

    申请日:2006-04-03

    IPC分类号: F16K31/00 F16K31/18

    摘要: Provided is a microvalve having a magnetic wax plug which includes a micro fluidic structure having an inlet portion and an outlet portion, a magnetic wax plug provided at a predetermined section where the inlet portion and the outlet portion meet, existing in a solid state, melted at a temperature higher than a predetermined temperature, and reversibly moving along a magnetic field, so as to control flux of a fluid through the micro fluidic structure, a heating portion provided corresponding to the section and heating the magnetic wax plug to be melted, and a magnetic field application portion selectively applying a magnetic field to a position where the melted magnetic wax plug arrives.

    摘要翻译: 提供一种具有磁性蜡塞的微型阀,其包括具有入口部分和出口部分的微流体结构,设置在入口部分和出口部分相遇的预定部分处的固体状态的熔融蜡 在高于预定温度的温度下,并且沿着磁场可逆地移动,以便控制通过微流体结构的流体的通量;对应于该部分设置的加热部分,并加热待熔化的磁性蜡塞;以及 选择性地将磁场施加到熔融的磁性蜡塞到达的位置的磁场施加部。

    Apparatus for circulating carrier fluid
    20.
    发明授权
    Apparatus for circulating carrier fluid 失效
    载体流体循环装置

    公开(公告)号:US07329535B2

    公开(公告)日:2008-02-12

    申请号:US10292012

    申请日:2002-11-11

    摘要: Provided are an apparatus for circulating a carrier fluid having two or more chambers or sections, an apparatus for amplifying a nucleic acid using the same, and a chip containing the same. The apparatus for circulating a carrier fluid includes two or more chambers maintained at different temperatures, each chamber having an inlet valve containing a pneumatic air pressure port for controlling inflow of the carrier fluid to the chamber (inlet pneumatic air pressure port), and an outlet valve containing a pneumatic air pressure for controlling outflow of the carrier fluid from the chamber (outlet pneumatic air pressure port), wherein the chambers are sequentially connected such that the outlet valve of one chamber is connected to the inlet valve of an adjacent chamber in a direction the fluid flows.

    摘要翻译: 提供一种用于循环具有两个或更多个室或部分的载体流体的装置,用于使用其的核酸的放大装置和含有该核酸的芯片的装置。 用于循环载体流体的装置包括保持在不同温度的两个或更多个室,每个室具有入口阀,该入口阀包含用于控制载体流体流入室(进气气压端口)的气动空气压力端口,以及出口 阀包含用于控制从腔室(出口气动空气压力端口)流出的载气的气动空气压力,其中腔室顺序地连接,使得一个室的出口阀连接到相邻室的入口阀 方向流体流动。