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    METHOD FOR CLARIFYING INDUSTRIAL WASTEWATER
    12.
    发明申请
    METHOD FOR CLARIFYING INDUSTRIAL WASTEWATER 审中-公开
    澄清工业废水的方法

    公开(公告)号：US20130075341A1

    公开(公告)日：2013-03-28

    申请号：US13491008

    申请日：2012-06-07

    Applicant: Robert Davis ,  Stuart Davis

    Inventor： Robert Davis ,  Stuart Davis

    IPC: C02F1/54

    CPC classification number: B01D17/048

    Abstract: Methods are described for removing contaminates from aqueous industrial wastewater process streams, specifically industrial laundries to yield a less contaminated aqueous effluent for discharge to a sewer and reduce the sludge generated therefrom. A premixed medium/high molecular weight and medium/high charged cationic coagulant solution polymer and an inorganic aluminum species is added to the wastewater, and after at least a two second delay, a high molecular weight highly charged anionic flocculent is injected into the wastewater which reduces sludge generation, while maintaining or exceeding effluent quality. Also, no coagulant, flocculent or sludge aids are needed to attain the results and the sludge can be dewatered in a plate and frame press.

    Abstract translation: 描述了用于从水性工业废水工艺流，特别是工业洗涤物中除去污染物的方法，以产生较少污染的含水废水排放到下水道并减少由其产生的污泥。 向废水中加入预混合的中等/高分子量和中等/高电荷的阳离子凝结剂溶液聚合物和无机铝物质，至少延迟两秒钟后，将高分子量高电荷的阴离子絮凝剂注入废水中 减少污泥产生，同时保持或超过污水质量。 此外，不需要凝结剂，絮凝剂或污泥辅助剂来获得结果，并且污泥可以在板框压机中脱水。

    METHOD FOR CLARIFYING INDUSTRIAL WASTEWATER
    13.
    发明申请
    METHOD FOR CLARIFYING INDUSTRIAL WASTEWATER 审中-公开

    公开(公告)号：US20130075339A1

    公开(公告)日：2013-03-28

    申请号：US13453484

    申请日：2012-04-23

    Applicant: Robert DAVIS ,  Stuart DAVIS

    Inventor： Robert DAVIS ,  Stuart DAVIS

    IPC: B01D17/04

    CPC classification number: B01D17/048

    Abstract: Methods are described for removing contaminates from aqueous industrial wastewater process streams, specifically industrial laundries to yield a less contaminated aqueous effluent for discharge to a sewer and reduce the sludge generated therefrom. A premixed medium/high molecular weight and medium/high charged cationic coagulant solution polymer and an inorganic aluminum species is added to the wastewater, and after at least a two second delay, a high molecular weight highly charged anionic flocculent is injected into the wastewater which reduces sludge generation, while maintaining or exceeding effluent quality. Also, no coagulant, flocculent or sludge aids are needed to attain the results and the sludge can be dewatered in a plate and frame press.

    Methods for stabilizing proteins
    14.
    发明授权
    Methods for stabilizing proteins 有权
    稳定蛋白质的方法

    公开(公告)号：US07282571B2

    公开(公告)日：2007-10-16

    申请号：US10771595

    申请日：2004-02-03

    Applicant: Ashley Stuart Davis ,  Kim Maria Middleton

    Inventor： Ashley Stuart Davis ,  Kim Maria Middleton

    IPC: C07K14/435

    CPC classification number: C07K14/4716

    Abstract: In basic research and drug discovery there is a need to provide protein reagents with high activity. In particular proteins that are used in assays must have a good shelf life and a consistent activity. As a system of measuring actin polymerization, pyrene labeled actin was developed in 1983 by Kouyama and Mihashi. However, prior to this disclosure, pyrene actin has been impossible to store for longer than one month because the activity would be lost due to protein denaturation and frozen pyrene actin immediately lost activity. This disclosure relates a method for stabilizing pyrene labeled actin for extended storage times and an optimal storage buffer thus creating a reproducible source of pyrene actin for various assays. Using the processes described herein, pyrene actin has been stored for greater than 3 years at 4° C. which makes it a viable product for retail.

    Abstract translation: 在基础研究和药物发现方面，需要提供高活性的蛋白质试剂。 特别是用于测定中的蛋白质必须具有良好的保质期和一致的活性。 作为测量肌动蛋白聚合的系统，1983年由Kouyama和Mihashi开发了芘标记的肌动蛋白。 然而，在本公开之前，芘肌动蛋白不可能存储超过一个月，因为活性将由于蛋白质变性而丧失，并且冷冻的芘肌动蛋白立即失去活性。 本公开涉及一种用于稳定芘标记的肌动蛋白以延长储存时间的方法和最佳储存缓冲液，从而为各种测定产生芘肌动蛋白的可重复来源。 使用本文所述的方法，芘肌动蛋白已经在4℃下储存超过3年，这使其成为零售的可行产品。

    Anti-S-phase tubulin ligands
    15.
    发明授权
    Anti-S-phase tubulin ligands 失效
    抗S相微管蛋白配体

    公开(公告)号：US07259278B2

    公开(公告)日：2007-08-21

    申请号：US09725030

    申请日：2000-11-29

    Applicant: Ashley Stuart Davis ,  Kim Maria Middleton ,  Jain Dong Jiang ,  J. George Bekesi

    Inventor： Ashley Stuart Davis ,  Kim Maria Middleton ,  Jain Dong Jiang ,  J. George Bekesi

    IPC: C07C237/28

    CPC classification number: C07C233/54 ,  A61K45/06

    Abstract: It is presently accepted that the mechanism of action for all anti-tumor tubulin ligands involves the perturbation of microtubule dynamics during the G2/M phase of cell division and subsequent entry into apoptosis (1). In this invention, we report a novel tubulin ligands which have a unique mechanism of action. These compounds, halogenated derivatives of acetamido benzoyl ethyl ester (HAABE), arrest cancer cells in S-phase and cause cell death by a combination of apoptosis (DNA ladder) and necrosis (DNA degradation) type mechanisms. Normal cells are not affected at the same concentrations of compound. The ligands bind covalently to tubulin in vitro and in vivo and shows potent cancericidal activity in tissue culture assays and in animal tumor models. These compounds target early S-phase at the G1/S transition rather than the G2/M phase and mitotic arrest. Bcl-2 phosphorylation, a marker of mitotic microtubule inhibition by other tubulin ligands was dramatically altered, phosphorylation was rapid and biphasic rather than a slow linear event. The halogenated ethyl ester series of derivatives thus constitute a unique set of tubulin ligands which induce a novel mechanism of cancer cell death.

    Abstract translation: 目前所接受的是，所有抗肿瘤微管蛋白配体的作用机制涉及在细胞分裂的G2 / M期和随后进入凋亡期间微管动力学的扰动（1）。 在本发明中，我们报道了一种具有独特作用机制的新型微管蛋白配体。 这些化合物，乙酰氨基苯甲酰基乙酯（HAABE）的卤化衍生物通过凋亡（DNA梯度）和坏死（DNA降解）类型机制的组合阻止S期的癌细胞并引起细胞死亡。 正常细胞在相同浓度的化合物下不受影响。 配体在体外和体内共价结合到微管蛋白上，并且在组织培养测定和动物肿瘤模型中显示出有效的杀癌活性。 这些化合物在G1 / S转换期间靶向早期S期，而不是G2 / M期和有丝分裂停滞。 Bcl-2磷酸化，其他微管蛋白配体的有丝分裂微管抑制的标志物显着改变，磷酸化是快速和双相而不是缓慢的线性事件。 卤代乙酯系列衍生物因此构成了一组独特的微管蛋白配体，其诱导癌细胞死亡的新机制。

    High speed valve assembly
    16.
    发明申请
    High speed valve assembly 有权
    高速阀门总成

    公开(公告)号：US20070152515A1

    公开(公告)日：2007-07-05

    申请号：US11411060

    申请日：2006-04-25

    Applicant: William Motherway ,  Stuart Davis

    Inventor： William Motherway ,  Stuart Davis

    IPC: H02K41/00 ,  H02K21/00

    CPC classification number: H02K41/031 ,  H02K1/145 ,  H02K1/2733 ,  H02K1/32 ,  H02K3/24 ,  H02K7/14 ,  H02K2207/03 ,  Y10T29/53191 ,  Y10T137/0753 ,  Y10T137/0989

    Abstract: Apparatus and associated systems or methods include a linear machine with an elongate, axially-slidable core member (i.e., shaft). In one embodiment, the shaft includes at least one radial aperture to provide fluid (e.g., air) communication from an interior volume of a winding tube that contains one or more stationary windings, to either end of the shaft through a lumen that extends axially through the length of the shaft. The stationary windings are spaced apart to permit fluid to flow through a plurality of radial apertures in the winding tube. In particular, fluid circulation across the windings may provide sufficient cooling to increase the machine's maximum current rating. The fluid circulation may also provide pneumatic processing capabilities (e.g., vacuum hold, blow-off). In one exemplary embodiment, the apparatus may be used to insert tube-and-square paper separators into battery casings at high rates.

    Abstract translation: 设备和相关系统或方法包括具有细长的可轴向滑动的芯构件（即，轴）的线性机器。 在一个实施例中，轴包括至少一个径向孔，以从包含一个或多个静止绕组的缠绕管的内部容积提供流体（例如，空气）连通到轴的任一端，该腔通过轴向延伸穿过 轴的长度。 固定绕组间隔开以允许流体流过绕组管中的多个径向孔。 特别地，跨绕组的流体循环可以提供足够的冷却以增加机器的最大额定电流。 流体循环还可以提供气动处理能力（例如，真空保持，吹扫）。 在一个示例性实施例中，该装置可用于以高速率将管和方形纸分离器插入电池壳体。

    Electrochemical cell systems comprising fuel consuming agents
    17.
    发明申请
    Electrochemical cell systems comprising fuel consuming agents 有权
    包含燃料消耗剂的电化学电池系统

    公开(公告)号：US20070048586A1

    公开(公告)日：2007-03-01

    申请号：US11585404

    申请日：2006-10-24

    Applicant: Stuart Davis

    Inventor： Stuart Davis

    IPC: H01M8/02 ,  B05D5/12

    CPC classification number: C01B5/00 ,  F17C11/005 ,  H01M8/04089 ,  H01M8/22 ,  H01M8/247

    Abstract: Electrochemical cell systems are provided. In some implementations, the electrochemical cell system includes a fuel cell and a fuel cartridge connected to the fuel cell. The fuel cell includes (i) a fuel cell housing having a first external surface and a first internal surface defining a first internal volume of the fuel cell housing, and (ii) a cathode, and anode, and an electrolyte disposed within the first internal volume. The fuel cartridge includes (i) a cartridge housing having a second external surface and a second internal surface defining a second internal volume of the cartridge housing, wherein the second internal volume includes a fuel; and (ii) a fuel consuming agent disposed on at least one of the first external surface and the second external surface.

    Abstract translation: 提供电化学电池系统。 在一些实施方案中，电化学电池系统包括燃料电池和连接到燃料电池的燃料盒。 燃料电池包括（i）燃料电池壳体，其具有第一外表面和限定燃料电池壳体的第一内部体积的第一内表面，以及（ii）阴极和阳极以及设置在第一内部内部的电解质 卷。 燃料盒包括（i）具有第二外表面的盒壳体和限定盒壳体的第二内部容积的第二内表面，其中第二内部容积包括燃料; 和（ii）设置在所述第一外表面和所述第二外表面中的至少一个上的燃料消耗剂。

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