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公开(公告)号：US09750627B2
公开(公告)日：2017-09-05
申请号：US14980473
申请日：2015-12-28
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F. A. Hossainy
IPC: A61F2/958 , A61F2/00 , A61F2/844 , A61F2/915 , A61L29/04 , A61L29/08 , A61L29/16 , A61L31/04 , A61L31/10 , A61L31/16 , A61M25/00 , A61M25/10
CPC classification number: A61F2/958 , A61F2/00 , A61F2/844 , A61F2/915 , A61F2250/0067 , A61L29/043 , A61L29/085 , A61L29/16 , A61L31/042 , A61L31/10 , A61L31/16 , A61L2300/204 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61L2400/10 , A61M25/007 , A61M25/10 , A61M2025/105
Abstract: Embodiments of the present invention include methods of treating, preventing, and/or ameliorating a vascular disease and/or disorder in a diabetic or pre-diabetic patient. The methods include implanting a stent in a vascular region in a diabetic or pre-diabetic patient, and prior to and/or during the implantation procedure, delivering a lubricant formulation to the vascular region. The stent may be a bare metal stent, or a drug eluting stent, such as a metal stent with a coating including a drug, such as everolimus or sirolimus.
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公开(公告)号：US09629944B2
公开(公告)日：2017-04-25
申请号：US15160999
申请日：2016-05-20
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： O. Mikael Trollsas , Michael H. Ngo , David J. Sherman , Syed F. A. Hossainy
IPC: A61F2/00 , A61L31/16 , A61L27/34 , A61L31/10 , A61K31/33 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/44 , A61K45/06 , A61K47/34 , A61K9/50 , A61K31/436 , A61L31/14
CPC classification number: A61L31/10 , A61K9/5031 , A61K9/5089 , A61K31/33 , A61K31/436 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/446 , A61K45/06 , A61K47/34 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02 , C08L71/02 , C08L67/04
Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
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13.发明授权Polymer-bioceramic composite implantable medical device with different types of bioceramic particles 有权具有不同类型生物陶瓷颗粒的聚合物 - 生物陶瓷复合植入式医疗装置公开(公告)号：US09199004B2
公开(公告)日：2015-12-01
申请号：US13933071
申请日：2013-07-01
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , David C. Gale , Syed F. A. Hossainy
Abstract: Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed.
Abstract translation: 公开了由具有不同类型的生物陶瓷颗粒的聚合物/生物陶瓷复合材料制成的植入式医疗装置。
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14.发明授权公开(公告)号：US08895056B2
公开(公告)日：2014-11-25
申请号：US13725525
申请日：2012-12-21
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , Paul M. Consigny , Ronald W. Heil, Jr. , Florian Niklas Ludwig , Dariush Davalian , Li Zhao , Irina Astafieva , Jinping Wan , Fozan El-Nounou , Katsuyuki Murase , Syed F. A. Hossainy , Rachel Bright , Jeffrey Ellis
CPC classification number: A61M25/1002 , A61F2/82 , A61F2250/0067 , A61K31/27 , A61K31/44 , A61K31/56 , A61K31/66 , A61K38/1709 , A61L29/08 , A61L29/16 , A61L31/08 , A61L31/16 , A61L2300/112 , A61L2300/216 , A61L2300/252 , A61L2300/40 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61L2300/62 , A61M25/10 , A61M37/0015 , A61M2025/105 , A61M2025/1086 , A61M2037/0023 , A61M2037/0061 , A61M2210/12
Abstract: The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well.
Abstract translation: 本发明涉及用于治疗血管疾病的治疗剂的区域递送，其中区域递送是指将治疗有效量的治疗剂递送至血管的区域，该区域不仅包括受到损伤的组织而且包括非折磨组织 受影响组织的外围也是如此。
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15.发明授权Methods of forming coating layers for medical devices utilizing flash vaporization 有权利用闪蒸法形成用于医疗器械的涂层的方法公开(公告)号：US08828418B2
公开(公告)日：2014-09-09
申请号：US14051214
申请日：2013-10-10
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Florian N. Ludwig , Syed F. A. Hossainy , Srinivasan Sridharan , Carol Lee
CPC classification number: A61L31/10 , A61L27/34 , A61L27/50 , A61L27/54 , A61L2300/406 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61M31/002
Abstract: Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents.
Abstract translation: 公开了用于控制活性剂从包含聚合物基质和一种或多种活性剂的医疗装置的涂层的形态和释放速率的方法。 所述方法包括在从涂料组合物中除去溶剂之前固定活性剂的形态或相分布。 涂层可用于控制活性剂或活性剂的组合的递送。
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Patent Agency Ranking
公开(公告)号：US10143572B2
公开(公告)日：2018-12-04
申请号：US14121435
申请日：2014-09-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Richard Rapoza , Susan Veldhof , James Oberhauser , Syed F. A. Hossainy
Abstract: A method of treating vascular disease in a patient is disclosed that comprises deploying a bioabsorbable polymer scaffold composed of a plurality of struts at a stenotic segment of an artery of a patient, wherein after the scaffold supports the segment at an increased diameter for a period of time the polymer degrades and is progressively replaced by de novo formation of malleable provisional matrix comprising proteoglycan, wherein as the scaffold becomes more malleable and becomes disconnected as it degrades, wherein following coverage of the struts by a neointima layer and loss of mechanical support provided by the scaffold, the scaffold is pulled outward by positive remodeling of the vessel wall of the scaffolded segment.
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公开(公告)号：US10076591B2
公开(公告)日：2018-09-18
申请号：US15192973
申请日：2016-06-24
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar W. Kleiner , Syed F. A. Hossainy , Mikael Trollsas , Stephen D. Pacetti
CPC classification number: A61L31/148 , A61L31/10 , A61L31/16 , A61L2300/41 , A61L2300/416 , A61L2300/42 , A61L2420/02 , A61L2420/08 , C08L67/04
Abstract: The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.
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公开(公告)号：US09808362B2
公开(公告)日：2017-11-07
申请号：US14712647
申请日：2015-05-14
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F. A. Hossainy , David C. Gale , Stephen Dirk Pacetti , Bin Huang
CPC classification number: A61F2/86 , A61F2210/0076 , A61F2230/0069 , A61L31/10 , A61L31/129
Abstract: Stents fabricated from polymer composites toughened by a dispersed phase are disclosed.
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公开(公告)号：US09622891B2
公开(公告)日：2017-04-18
申请号：US14687843
申请日：2015-04-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Benjamyn Serna , Michael Huy Ngo , Syed F. A. Hossainy , O. Mikael Trollsas
CPC classification number: A61F2/95 , A61F2210/0076 , A61F2230/0063 , A61F2240/001 , A61F2250/0067 , A61L2420/02 , B05D1/002 , B05D1/38 , B05D3/10 , B05D3/12
Abstract: Embodiments of the present invention encompass methods of forming coatings, particularly coatings for medical devices, and more particularly, for braided or woven medical devices. Embodiments of the present invention encompass the coatings and the coated devices. The coatings may include a polymer and optionally a therapeutic agent.
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20.发明授权公开(公告)号：US09381280B2
公开(公告)日：2016-07-05
申请号：US14304792
申请日：2014-06-13
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F. A. Hossainy , Stephen D. Pacetti
IPC: C08F6/00 , A61L31/14 , A61L31/06 , C08J3/18 , C08J9/00 , B29C45/00 , B29C71/00 , B29C71/02 , C08J3/00 , B29K33/04 , B29L31/00
CPC classification number: A61L31/141 , A61L31/06 , A61L31/148 , A61L2400/00 , B29C45/0053 , B29C45/72 , B29C71/0009 , B29C71/02 , B29C2071/0027 , B29C2071/022 , B29K2033/04 , B29K2067/04 , B29L2031/753 , C08J3/18 , C08J9/00 , C08J2207/10 , C08J2300/16 , C08K5/0016
Abstract: Methods of making polymeric devices, such as stents, with one or more modifications such as addition of plasticizers, to improve processing, and the devices made by these methods.
Abstract translation: 制备聚合物装置（例如支架）的方法，具有一种或多种改性，例如添加增塑剂以改善加工，以及通过这些方法制备的装置。
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