Process for preparing enantiomer-enriched alpha-hydroxycarboxylic acids and amides
    17.
    发明申请
    Process for preparing enantiomer-enriched alpha-hydroxycarboxylic acids and amides 审中-公开
    制备富含对映异构体的α-羟基羧酸和酰胺的方法

    公开(公告)号:US20070020741A1

    公开(公告)日:2007-01-25

    申请号:US10575386

    申请日:2004-10-07

    IPC分类号: C12P7/40 C12N9/80

    CPC分类号: C12P7/42 C12P13/02

    摘要: The present invention describes an enzymatic process for preparing enantiomer-enriched α-hydroxycarboxylic acids and amides which comprises, in one step, the conversion of a carbonyl compound to the corresponding acid/amides via the intermediate stage of a cyanohydrin. The invention also provides a reaction system operating in such a way and a whole-cell catalyst that is advantageous for use for this reaction.

    摘要翻译: 本发明描述了制备富含对映异构体的α-羟基羧酸和酰胺的酶促方法,其包括在一步中通过氰醇的中间阶段将羰基化合物转化为相应的酸/酰胺。 本发明还提供了以这种方式操作的反应体系和对于该反应有利的全细胞催化剂。