Polyaromatic heterocyclic compounds and pharmaceutical compositions comprised thereof
    14.
    发明授权
    Polyaromatic heterocyclic compounds and pharmaceutical compositions comprised thereof 失效
    多芳族杂环化合物及其组合物

    公开(公告)号:US06194450B1

    公开(公告)日:2001-02-27

    申请号:US09121188

    申请日:1998-07-23

    IPC分类号: A61K3135

    摘要: Novel pharmaceutically/cosmetically-active polyaromatic heterocyclic compounds have the structural formula (I): in which Z is a divalent radical selected from among —O—, —S— or —Nr′— and Ar is either a radical having the following structural formula (II): or a radical having the following structural formula (III): and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

    摘要翻译: 新的药物/化妆活性多芳族杂环化合物具有结构式(I):其中Z是选自-O - , - S-或-Nr - 的二价基团,Ar是具有以下结构式的基团 (II):或具有以下结构式(III)的基团:并且可用于治疗各种疾病状态,无论是人类还是兽医,例如皮肤病学,风湿性,呼吸道,心血管和眼科疾病,以及 对于哺乳动物皮肤和毛发状况/病症的治疗。