Abstract:
The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
Abstract:
An oral care implement includes a collection system for oral fluids. Some embodiments of the implement may include a body comprising a head, a handle, and a neck located between the head and the handle, the head having a front surface and an opposite rear surface. Tooth cleaning elements may extend from the front surface of the head. A collecting member may be coupled to the body and a reservoir may be located within the handle or the neck of the body. A fluid pathway may extend from the collecting member to the reservoir so that an oral fluid can pass through the collecting member and into the reservoir for storage.
Abstract:
The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
Abstract:
An in vitro method for determining the bioavailability of zinc (II) ions from an oral care composition comprises: providing a sample comprising, the oral care composition; contacting the sample with a biorelevant substrate, separating the biorelevant substrate from the sample, contacting the biorelevant substrate with an indicator under conditions selected such that the indicator is capable of reacting with zinc (II) ions, and determining a light absorbance of the indicator. The indicator is zincon or a salt thereof. The method is useful for estimating the ability of an oral care composition to deliver therapeutically-active zinc (II) ions to the oral cavity. Also provided is the use of zincon and a biorelevant substrate in vitro to determine the bioavailability of zinc (II) ions from an oral care composition comprising, a zinc source.
Abstract:
An oral care implement includes a collection system for oral fluids. Some embodiments of the implement may include a body comprising a head, a handle, and a neck located between the head and the handle, the head having a front surface and an opposite rear surface. Tooth cleaning elements may extend from the front surface of the head. A collecting member may be coupled to the body and a reservoir may be located within the handle or the neck of the body. A fluid pathway may extend from the collecting member to the reservoir so that an oral fluid can pass through the collecting member and into the reservoir for storage.
Abstract:
Provided are compositions, e.g., oral and personal care products, comprising (i) a zinc (amino acid or trialkyl glycine) halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.
Abstract:
A method of monitoring oral health including deriving a health profile of a user from information obtained from a sample taken from the user; displaying a representation of the health profile on a display, wherein the representation of the health profile includes a list of undesirable oral health characteristics that are detectable from the sample and a graphical depiction of an oral cavity divided into a plurality of regions; and wherein in response to selection of a first one of the undesirable oral health characteristics, the representation of the health profile indicates which regions of the user's oral cavity are affected by the first one of the undesirable oral health characteristic.