-
公开(公告)号：US10829748B2
公开(公告)日：2020-11-10
申请号：US16305348
申请日：2017-06-08
Applicant: DSM IP Assets B.V.
Inventor： Rene Marcel De Jong , Willem Bijleveld , Evert Tjeerd Van Rij
IPC: C12N9/20 , C12N1/20 , C12N1/14 , C12N15/52 , C12N15/63 , A23C13/16 , A23C15/12 , A23C19/06 , A23C19/082
Abstract: The present invention relates to a polypeptide having lipase activity wherein the polypeptide, which, when aligned with a polypeptide according to SEQ ID NO: 1, comprises at least one amino acid substitution resulting in Ser (S), Ala (A) or Leu (L) at position 246, Trp (W) at position 307, Leu (L) at position 345, Ile (I) at position 365, and/or Phe (F) at position 534, wherein the position is defined with reference to SEQ ID NO: 1, wherein Ala(A) at position 1 in SEQ ID NO: 1 is counted as number 1 and a method for preparing the polypeptide.The present invention further relates to a process for preparing a food product wherein a polypeptide according to the present invention is used.
-
公开(公告)号：US10787649B2
公开(公告)日：2020-09-29
申请号：US16316988
申请日：2017-07-11
Applicant: DSM IP ASSETS B.V.
Inventor： Alrik Pieter Los , Rene Marcel De Jong , Remko Tsjibbe Winter , Ben Den Dulk
Abstract: The present invention relates to a recombinant host cell which is capable of producing a dicarboxylic acid and which comprises a mutant malate dehydrogenase resulting in an increased production of the dicarboxylic acid. The invention also relates to a process for producing a dicarboxylic acid, which method comprises fermenting said recombinant host cell in a suitable fermentation medium and producing the dicarboxylic acid.
-
公开(公告)号：US10273507B2
公开(公告)日：2019-04-30
申请号：US14434116
申请日：2013-10-15
Applicant: DSM IP ASSETS B.V.
Inventor： Maria Bernedina Elizabeth Jonkers , Paul Klaassen , Aloysius Wilhelmus Rudolphus Hubertus Teunissen , Rene Marcel De Jong
IPC: C12N1/16 , C12N1/22 , C12N9/88 , C12P7/06 , C12P7/10 , C12N9/10 , C12N9/12 , C12N9/90 , C12N9/92
Abstract: The invention relates to a cell capable of converting one or more pentose sugar and one or more hexose sugar into fermentation product constitutively expressing one or more heterologous or homologous polypeptide having the amino acid sequence set out in SEQ ID NO: 20, or a variant polypeptide thereof having at least 45% identity to SEQ ID NO 20. In an embodiment the heterologous polypeptide has glyoxalase activity.
-
公开(公告)号：US10100320B2
公开(公告)日：2018-10-16
申请号：US15612728
申请日：2017-06-02
Applicant: DSM IP ASSETS B.V.
IPC: C12N15/81 , C12N9/92 , C12P7/10 , C12P7/16 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/54 , C12P7/56 , C12P5/02 , C12P7/06 , C12P35/00
Abstract: The invention relates to a cell which comprises a nucleotide sequence encoding a xylose isomerase, wherein the amino acid sequence of the xylose isomerase has at least 75% sequence identity to the amino acid sequence set out in SEQ ID NO: 2 and wherein the nucleotide sequence is heterologous to the host. A cell of the invention may be used in a process for producing a fermentation product, such as ethanol. Such a process may comprise fermenting a medium containing a source of xylose with a cell of the invention such that the cell ferments xylose to the fermentation product.
-
公开(公告)号：US09988615B2
公开(公告)日：2018-06-05
申请号：US14763263
申请日：2014-02-03
Applicant: DSM IP ASSETS B.V.
Inventor： Alrik Pieter Los , Rene Marcel De Jong , Maaike Appeldoorn
CPC classification number: C12N9/2402 , C12P19/02 , C12P19/12 , C12P19/14 , C12Y302/01
Abstract: The invention relates to a polypeptide having hemicellulase activity. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional protein and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.
-
Patent Agency Ranking
公开(公告)号：US09808018B2
公开(公告)日：2017-11-07
申请号：US14767406
申请日：2014-02-27
Applicant: DSM IP ASSETS B.V.
Inventor： Rene Marcel De Jong , Hanna Elisabet Abbas , Evert Tjeerd Van Rij
CPC classification number: A21D8/042 , C12N9/2417 , C12Y302/01001
Abstract: A variant polypeptide having alpha-amylase activity, wherein the variant has an amino acid sequence which, when aligned with the alpha-amylase comprising the sequence set out in SEQ ID NO: 2, comprises at least one substitution of an amino acid residue.Such a variant polypeptide may be used in the preparation of a baked product.
-
公开(公告)号：US20150275235A1
公开(公告)日：2015-10-01
申请号：US14434116
申请日：2013-10-15
Applicant: DSM IP ASSETS B.V.
Inventor： Maria Bernedina Elizabeth Jonkers , Paul Klaassen , Aloysius Wilhelmus Rudolphus Hubertus Teunissen , Rene Marcel De Jong
CPC classification number: C12P7/06 , C12N1/16 , C12N1/22 , C12N9/1022 , C12N9/1205 , C12N9/88 , C12N9/90 , C12N9/92 , C12P7/10 , C12Y202/01001 , C12Y202/01002 , C12Y207/01017 , C12Y404/01005 , C12Y501/03001 , C12Y503/01006 , Y02E50/16 , Y02E50/17
Abstract: The invention relates to a cell capable of converting one or more pentose sugar and one or more hexose sugar into fermentation product constitutively expressing one or more heterologous or homologous polypeptide having the amino acid sequence set out in SEQ ID NO: 20, or a variant polypeptide thereof having at least 45% identity to SEQ ID NO 20. In an embodiment the heterologous polypeptide has glyoxalase activity.
Abstract translation: 本发明涉及一种能够将一种或多种戊糖和一种或多种己糖转化成组成型表达一种或多种具有SEQ ID NO：20所示氨基酸序列的异源或同源多肽的发酵产物的细胞，或变体多肽 其与SEQ ID NO 20具有至少45％的同一性。在一个实施方案中，异源多肽具有乙二醛酶活性。
-
公开(公告)号：US11339379B2
公开(公告)日：2022-05-24
申请号：US16999962
申请日：2020-08-21
Applicant: DSM IP ASSETS B.V.
Inventor： Alrik Pieter Los , Rene Marcel De Jong , Remko Tsjibbe Winter , Ben Den Dulk
Abstract: The present invention relates to a recombinant host cell which is capable of producing a dicarboxylic acid and which comprises a mutant malate dehydrogenase resulting in an increased production of the dicarboxylic acid. The invention also relates to a process for producing a dicarboxylic acid, which method comprises fermenting said recombinant host cell in a suitable fermentation medium and producing the dicarboxylic acid.
-
公开(公告)号：US10918113B2
公开(公告)日：2021-02-16
申请号：US16471159
申请日：2017-12-19
Applicant: DSM IP Assets B.V.
Inventor： Rene Marcel De Jong , Chantal Christis , Neil Carr
Abstract: The present disclosure describes a variant polypeptide having lipolytic activity, wherein the variant has an amino acid sequence which, when aligned with the amino acid sequence as set out in SEQ ID NO: 2, comprises at least one substitution of an amino acid residue at a position corresponding to any of the positions 53, 112, 141, 178, 179, 182, 202, 203, 235, 282, 284,
said positions being defined with reference to SEQ ID NO: 2, and wherein said variant has at least 70% identity with the mature polypeptide having lipolytic activity as set out in SEQ ID NO: 2.
Such a variant polypeptide may be used in the preparation of a baked product.-
公开(公告)号：US10604773B2
公开(公告)日：2020-03-31
申请号：US16352415
申请日：2019-03-13
Applicant: DSM IP ASSETS B.V.
Inventor： Maria Bernedina Elizabeth Jonkers , Paul Klaassen , Aloysius Wilhelmus Rudolphus Hubertus Teunissen , Rene Marcel De Jong
Abstract: The invention relates to a cell capable of converting one or more pentose sugar and one or more hexose sugar into fermentation product constitutively expressing one or more heterologous or homologous polypeptide having the amino acid sequence set out in SEQ ID NO: 20, or a variant polypeptide thereof having at least 45% identity to SEQ ID NO 20. In an embodiment the heterologous polypeptide has glyoxalase activity.
-
-
-
-
-
-
-
-
-
Search Results
25
records
(took 0.025 seconds)
