公开(公告)号：US07073442B2

公开(公告)日：2006-07-11

申请号：US10189166

申请日：2002-07-03

申请人： Jeffrey A. Fedor ,  Christopher M. Gaylo ,  Peter A. Materna

发明人： Jeffrey A. Fedor ,  Christopher M. Gaylo ,  Peter A. Materna

IPC分类号： B41F1/34 ,  B41F17/00 ,  B41J29/08 ,  F24C15/20

CPC分类号： B41J3/4073 ,  B22F3/1055 ,  B22F2003/1057 ,  B29C35/0288 ,  B29C41/36 ,  B29C41/46 ,  B29C41/52 ,  B29C43/34 ,  B29C64/165 ,  B29C2035/0822 ,  B29C2043/3494 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y40/00 ,  B33Y50/00 ,  Y02P10/295

摘要： Apparatus, systems and methods for use in three-dimensional printing are shown and described. Various embodiments of the invention allow for more precise and controlled delivery of heat to achieve interlayer drying; isolation of the working region from the outside for reasons of cleanliness and in connection with the vapors of organic solvents; better control of the temperature of the working region; better accuracy in the flowrates of binder fluid dispensed; matching of delivered flowrates for multiple dispensers; verification of delivered flowrate or drops; provision for easier changeover of the machine from one powder to another; cleanability; and other needs.

公开(公告)号：US06857436B2

公开(公告)日：2005-02-22

申请号：US10197287

申请日：2002-07-16

申请人： Mohamed Emam Labib ,  Ching-Yue Lai ,  Peter A. Materna ,  Geoffrey Lawrence Mahon

发明人： Mohamed Emam Labib ,  Ching-Yue Lai ,  Peter A. Materna ,  Geoffrey Lawrence Mahon

IPC分类号： A61C17/00 ,  A61C1/00 ,  A61C19/00 ,  A61L2/18 ,  A61L2/22 ,  A61M1/14 ,  A61M1/16 ,  B01D65/02 ,  B01D65/06 ,  B08B3/08 ,  B08B3/10 ,  B08B9/02 ,  B08B9/027 ,  B08B9/032 ,  C11D3/02 ,  C11D3/14 ,  C11D3/39 ,  C11D3/395 ,  C11D3/48 ,  C11D11/00 ,  C23G5/00 ,  B08B7/04

CPC分类号： C11D3/3956 ,  A61C1/0076 ,  A61L2/186 ,  A61L2/22 ,  A61L2202/24 ,  A61M1/1682 ,  A61M1/169 ,  B01D65/02 ,  B01D65/022 ,  B01D2321/04 ,  B01D2321/2066 ,  B08B9/032 ,  B08B9/0326 ,  B08B9/0327 ,  B08B2209/022 ,  C11D3/042 ,  C11D3/044 ,  C11D3/14 ,  C11D3/3947 ,  C11D3/48 ,  C11D11/0041 ,  C23G5/00

摘要： A method of cleaning surfaces using a mixed phase cleaning mixture of an aqueous solution and a flow of gas sufficient to produce droplets of the liquid which are entrained by the gas for a time sufficient to clean tubing of various lengths and geometries and porous membranes to remove biofilm, debris and contaminants.

摘要翻译： 使用水溶液的混合相清洗混合物和足以产生被气体夹带的液体的液滴的时间足以清洁各种长度和几何形状的管道以及多孔膜以去除的液体的清洗表面的方法 生物膜，碎屑和污染物。

公开(公告)号：US08545562B1

公开(公告)日：2013-10-01

申请号：US12752032

申请日：2010-03-31

申请人： Peter A. Materna ,  James Bruffey ,  Bret Hartzell ,  Dale G. Davison

发明人： Peter A. Materna ,  James Bruffey ,  Bret Hartzell ,  Dale G. Davison

IPC分类号： A61F2/44

CPC分类号： A61F2/442 ,  A61F2/4465 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/30357 ,  A61F2002/30365 ,  A61F2002/30367 ,  A61F2002/30433 ,  A61F2002/30482 ,  A61F2002/30504 ,  A61F2002/30517 ,  A61F2002/30522 ,  A61F2002/30543 ,  A61F2002/30576 ,  A61F2002/30579 ,  A61F2002/30607 ,  A61F2002/30616 ,  A61F2002/30774 ,  A61F2002/30785 ,  A61F2002/30787 ,  A61F2002/30822 ,  A61F2002/30825 ,  A61F2002/30828 ,  A61F2002/30845 ,  A61F2002/30846 ,  A61F2002/30848

摘要： An implant may provide a body capable of being fit in an intervertebral space and a spin-plate rotatable with respect to the body. The spin-plate may a blade. The blade may possess grooves in its flat faces, or may be provided with an overhang. The path of the overhang or groove may be such that as the spin-plate advances in its rotation, a vertebra engaged with the blade is drawn toward the body of the implant. Pins may be placed in adjacent vertebrae such as to engage the spin-plate. Surgical methods are also described.

摘要翻译： 植入物可以提供能够配合在椎间空间中的主体和相对于身体可旋转的旋转板。 旋转板可以是刀片。 刀片可以在其平面中具有凹槽，或者可以设置有突出部。 突出或凹槽的路径可以使得当旋转板在其旋转中前进时，与刀片接合的椎骨被拉向植入体的主体。 引脚可以放置在相邻的椎骨中，以便接合旋转板。 还描述了手术方法。

公开(公告)号：US07931914B2

公开(公告)日：2011-04-26

申请号：US10284430

申请日：2002-10-29

申请人： Wendy E. Pryce Lewis ,  Charles William Rowe ,  Michael J. Cima ,  Peter A. Materna

发明人： Wendy E. Pryce Lewis ,  Charles William Rowe ,  Michael J. Cima ,  Peter A. Materna

IPC分类号： A61K9/20 ,  A61K9/28 ,  A61K9/14 ,  A61K9/16 ,  A61K9/48 ,  A61F13/00

CPC分类号： A61K9/20 ,  A61J3/10 ,  A61K9/2095 ,  B29C64/00 ,  B29C64/165 ,  B29C67/0051 ,  B29C67/0081 ,  B29L2031/753 ,  B33Y70/00 ,  B33Y80/00

摘要： A uniaxially compressed dosage form manufactured by three-dimensional printing that preserves the predetermined internal architecture of the dosage form while producing an improved surface finish. The compression compacts the dosage form, eliminating at least some of the void space that remains at the end of conventional three-dimensional printing. Surface finish obtained as a result of the uniaxial compression process can be essentially equal to that obtained from conventional tablet pressing. Additionally, the internal structure or spatial variation of composition of the dosage form is preserved during the pressing operation, with geometric shrinkage occurring mostly in the direction of the axis of pressing. Further, as a result of compression, a greater quantity of API can be packed into a given final volume of dosage form.

摘要翻译： 通过三维印刷制造的单轴压缩剂型，其保持了剂型的预定内部结构，同时产生改进的表面光洁度。 压缩压缩剂型，消除了在传统三维印刷结束时保留的至少一些空隙空间。 作为单轴压缩方法的结果获得的表面光洁度可以基本上等于从常规压片获得的表面光洁度。 此外，在压制操作期间保留了剂型的组成的内部结构或空间变化，几何收缩主要发生在按压轴的方向上。 此外，作为压缩的结果，可以将更大量的API包装在给定的最终体积的剂型中。

公开(公告)号：US06772026B2

公开(公告)日：2004-08-03

申请号：US09972832

申请日：2001-10-05

申请人： Thomas J. Bradbury ,  Christopher M. Gaylo ,  James A. Fairweather ,  Kathleen D. Chesmel ,  Peter A. Materna ,  Adolphe Youssef

发明人： Thomas J. Bradbury ,  Christopher M. Gaylo ,  James A. Fairweather ,  Kathleen D. Chesmel ,  Peter A. Materna ,  Adolphe Youssef

IPC分类号： G06F1900

CPC分类号： G05B19/4099 ,  A61C8/0006 ,  A61C13/0004 ,  A61F2/2803 ,  A61F2/30942 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/2878 ,  A61F2002/30062 ,  A61F2002/3008 ,  A61F2002/30616 ,  A61F2002/30677 ,  A61F2002/30948 ,  A61F2002/30952 ,  A61F2002/30953 ,  A61F2002/30968 ,  A61F2210/0004 ,  A61F2250/0098 ,  A61F2310/00293 ,  A61K9/2095 ,  B29C64/135 ,  B33Y50/00 ,  B33Y80/00 ,  B65G2207/14 ,  G05B2219/35008 ,  G05B2219/35053 ,  G05B2219/35054 ,  G05B2219/35219 ,  G05B2219/35223 ,  G05B2219/45166 ,  G05B2219/45168 ,  G05B2219/49023 ,  G06F19/00 ,  G06F19/321 ,  G06F19/3418 ,  G06F19/3456 ,  G06Q10/06 ,  G06Q30/0601 ,  G06Q50/22 ,  G16H10/60 ,  G16H50/50

摘要： The rapid design and manufacture of biomedical devices such as implants, oral dosage pills and implantable pharmaceuticals employs electronic data and modeling transmissions via a computer network. Patient information and patient-specific radiological data is captured and transmitted via a computer network to a design and/or manufacturing site. A multi-dimensional digital model is created based on the radiological data and patient information. Communications interchanges between a clinical/diagnostic site and a design/manufacturing site permit modification of the digital model until approved. The approved digital model is converted into machine instructions to construct the biomedical device. Alternatively, the digital model is employed in a best fit selection of a biomedical device from a pre-existing set of biomedical devices or machine-instructions. Transmittal of data over computer networks is further directed to the use of a Website to perform various client-interaction and follow-up tasks.

公开(公告)号：US6106281A

公开(公告)日：2000-08-22

申请号：US209326

申请日：1998-12-11

申请人： Peter A. Materna

发明人： Peter A. Materna

IPC分类号： B23K1/008 ,  F27B17/00 ,  F27D7/06 ,  F27D19/00 ,  F27D21/00 ,  F27D99/00 ,  F28D15/02 ,  F27B5/04

CPC分类号： B23K1/008 ,  F27B17/0016 ,  F27D19/00 ,  F27D7/06 ,  F28D15/02 ,  F27D2007/063 ,  F27D21/0014 ,  F27D99/0075

摘要： A temperature-controlled chamber, such as an inerted oven for soldering, in which the buoyancy-induced motion of gas at the opening of the chamber is suppressed by adjusting the densities of gases. In one embodiment the inertant gas is chosen to be a mixture of inert gases such that the density of warm gas inside the oven approximately equals the density of the external atmosphere. In another embodiment, a buffer region of density-matched warm air is provided between the warm inertant inside the oven and the external atmosphere. The result is reduction in the consumption of inertant.

摘要翻译： 诸如用于焊接的惰性烘箱的温度控制室，其中通过调节气体的密度来抑制气体在室的开口处的浮力引起的运动。 在一个实施方案中，惰性气体被选择为惰性气体的混合物，使得炉内温暖气体的密度近似等于外部气氛的密度。 在另一个实施例中，在炉内的暖惰性物质和外部气氛之间提供密度匹配的暖空气缓冲区。 结果是减少了惰性物质的消耗。