公开(公告)号：US20150225754A1

公开(公告)日：2015-08-13

申请号：US14421220

申请日：2013-08-19

Applicant: Evolva SA

Inventor： Thomas Oestergaard Tange ,  Michael Naesby ,  Christophe Folly ,  Fanny Delegrange ,  Jens Houghton-Larsen ,  Simon Carlsen

IPC: C12P9/00 ,  C12N9/10 ,  C12N15/81

CPC classification number: C12P9/00 ,  C12N1/16 ,  C12N9/1007 ,  C12N9/1085 ,  C12N9/88 ,  C12N15/52 ,  C12N15/63 ,  C12N15/81 ,  C12P5/007 ,  C12P5/026 ,  C12P7/00 ,  C12P7/04 ,  C12P15/00 ,  C12P17/10 ,  C12P23/00 ,  C12Y205/01068

Abstract: This invention provides recombinant cells and methods for producing terpenes and terpenoids by increasing production or accumulation or both of isoprenoid precursors thereof.

Abstract translation: 本发明提供了通过增加萜烯和萜类化合物的产生或积累或两者的类异戊二烯前体来制备重组细胞和方法。

公开(公告)号：US20230407360A1

公开(公告)日：2023-12-21

申请号：US18132027

申请日：2023-04-07

Applicant: EVOLVA SA

Inventor： Jens Houghton-Larsen ,  Paula Hicks ,  Michael Naesby ,  Thomas Tange Ostergaard ,  Jorgen Hansen ,  Michael Mikkelsen Dalgaard ,  Esben Hansen-Halkjaer ,  Ernesto Simon ,  Sabina Tavares

IPC: C12P19/56 ,  C12N9/88 ,  C12N9/06 ,  C12N9/02 ,  C12N9/10 ,  C12N9/90 ,  C12N15/81 ,  C12N15/82 ,  C12P19/44 ,  C12N15/63

CPC classification number: C12P19/56 ,  C12N9/88 ,  C12N9/0032 ,  C12N9/0073 ,  C12N9/0071 ,  C12N9/1051 ,  C12N9/1085 ,  C12N9/90 ,  C12N15/81 ,  C12N15/8243 ,  C12P19/44 ,  C12N15/63 ,  Y02P20/52

Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.

公开(公告)号：US20180080054A1

公开(公告)日：2018-03-22

申请号：US15665674

申请日：2017-08-01

Applicant: Evolva SA

Inventor： Thomas M. Ostergaard Tange ,  Michael Naesby ,  Christophe Folly ,  Fanny Delegrange ,  Jens Houghton-Larsen ,  Simon Carlsen

IPC: C12P9/00 ,  C12P7/00 ,  C12N9/10 ,  C12P7/04 ,  C12P23/00 ,  C12P17/10 ,  C12P15/00 ,  C12P5/02 ,  C12P5/00 ,  C12N15/52 ,  C12N9/88 ,  C12N1/16 ,  C12N15/81 ,  C12N15/63

CPC classification number: C12P9/00 ,  C12N1/16 ,  C12N9/1007 ,  C12N9/1085 ,  C12N9/88 ,  C12N15/52 ,  C12N15/63 ,  C12N15/81 ,  C12P5/007 ,  C12P5/026 ,  C12P7/00 ,  C12P7/04 ,  C12P15/00 ,  C12P17/10 ,  C12P23/00 ,  C12Y205/01068

Abstract: This invention provides recombinant cells and methods for producing terpenes and terpenoids by increasing production or accumulation or both of isoprenoid precursors thereof.

公开(公告)号：US09834800B2

公开(公告)日：2017-12-05

申请号：US14421220

申请日：2013-08-19

Applicant: Evolva SA

Inventor： Thomas Oestergaard Tange ,  Michael Naesby ,  Christophe Folly ,  Fanny Delegrange ,  Jens Houghton-Larsen ,  Simon Carlsen

IPC: C12N1/20 ,  C12N1/00 ,  C12P5/00 ,  C12P5/02 ,  C12P7/02 ,  C12P7/04 ,  C12P7/24 ,  C12P7/40 ,  C12P9/00 ,  C12P17/02 ,  C12P17/06 ,  C07H21/04 ,  C12N9/10 ,  C12N9/88 ,  C12N15/52 ,  C12P15/00 ,  C12P17/10 ,  C12N1/16 ,  C12P23/00 ,  C12N15/63 ,  C12P7/00 ,  C12N15/81

CPC classification number: C12P9/00 ,  C12N1/16 ,  C12N9/1007 ,  C12N9/1085 ,  C12N9/88 ,  C12N15/52 ,  C12N15/63 ,  C12N15/81 ,  C12P5/007 ,  C12P5/026 ,  C12P7/00 ,  C12P7/04 ,  C12P15/00 ,  C12P17/10 ,  C12P23/00 ,  C12Y205/01068

Abstract: This invention provides recombinant cells and methods for producing terpenes and terpenoids by increasing production or accumulation or both of isoprenoid precursors thereof.

公开(公告)号：US09828617B2

公开(公告)日：2017-11-28

申请号：US14421872

申请日：2013-08-13

Applicant: BASF SE ,  Evolva SA

Inventor： Michael Naesby ,  Christophe Folly ,  Curt Aimé Friis Nielsen ,  Anaelle Hatsch ,  Markus Schwab ,  Oskar Zelder ,  Stefan Haefner ,  Hartwig Schroeder ,  Birgit Hoff ,  Andrea Molt ,  Klaus Ditrich ,  Michael Breuer ,  Holger Hartmann ,  Karsten Koerber

IPC: C12N15/53 ,  C12P17/12 ,  C12N9/02 ,  C12N9/90 ,  C12N15/52 ,  C12P17/10 ,  C12P17/18 ,  C07D209/90 ,  C07D487/06 ,  C07K16/40 ,  C12N9/10

CPC classification number: C12P17/12 ,  C07D209/90 ,  C07D487/06 ,  C07K16/40 ,  C12N9/0004 ,  C12N9/001 ,  C12N9/1007 ,  C12N9/1085 ,  C12N9/90 ,  C12N15/52 ,  C12P17/10 ,  C12P17/182 ,  C12Y205/01

Abstract: Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as polypeptides, polynucleotides and vectors comprising such polynucleotides which can be applied in a method for the manufacture of clavine-type alkaloids are provided.