公开(公告)号：US20210380633A1

公开(公告)日：2021-12-09

申请号：US17409692

申请日：2021-08-23

Applicant: FUJIFILM CORPORATION

Inventor： Yosuke YAMAMOTO ,  Kazuhei KANEKO ,  Motomasa TAKAHASHI ,  Makoto TAKAHASHI ,  Mika IMAMURA ,  Hirotaka SATOU ,  Hirofumi OMURA ,  Yuji YOSHIMITSU ,  Keita TANAKA ,  Daisuke NAKAGAWA

IPC: C07K1/06 ,  C07K1/02

Abstract: Provided are a method for producing a peptide compound including a step of using an aromatic heterocyclic compound represented by Formula (1) represented by Formula (1); a protective group-forming reagent including the compound; and the compound. In Formula (1), a ring A represents an aromatic heterocyclic ring, YA's each independently represent —OH, —NHR, —SH, or —X0, where X0 represents Cl, Br, or I, RA and RC each independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group, RBs' each independently represent a monovalent aliphatic hydrocarbon group, a (1+c)-valent aromatic group, or a (1+c)-valent heteroaromatic group, where, in a case where both a and c is 0, RB is a monovalent aliphatic hydrocarbon group, and the number of carbon atoms in at least one aliphatic hydrocarbon group of RA, RB, or RC is 12 or more.

公开(公告)号：US20180215716A1

公开(公告)日：2018-08-02

申请号：US15940426

申请日：2018-03-29

Applicant: FUJIFILM Corporation

Inventor： Motomasa TAKAHASHI

IPC: C07D231/56 ,  B01J31/22

CPC classification number: C07D231/56 ,  B01J31/0202 ,  B01J31/22 ,  B01J31/2234 ,  B01J31/2239 ,  B01J2231/766 ,  B01J2531/824

Abstract: Provided is a method for producing an aromatic compound, which can produce a particular aromatic compound at high yield and can be industrially utilized. According to the invention, there is provided a method for producing an aromatic compound, including an aromatization reaction which includes reacting an oxime compound represented by Formula (1) with an acylating agent in the presence of a hydroquinone compound and a palladium compound, and thus obtaining an aromatic compound.

公开(公告)号：US20150152131A1

公开(公告)日：2015-06-04

申请号：US14621119

申请日：2015-02-12

Applicant: FUJIFILM Corporation

Inventor： Kouki NAKAMURA ,  Satoshi SHIMAMURA ,  Junichi IMOTO ,  Motomasa TAKAHASHI ,  Katsuyuki WATANABE ,  Kenji WADA ,  Yuuta FUJINO ,  Takuya MATSUMOTO ,  Makoto TAKAHASHI ,  Hideki OKADA ,  Takehiro YAMANE ,  Takayuki ITO

IPC: C07H19/06 ,  C07C69/78 ,  C07C251/38 ,  C07C309/73 ,  C07H7/04 ,  C07H1/00

CPC classification number: C07D333/32 ,  A61K31/7068 ,  C07B53/00 ,  C07C45/00 ,  C07C47/277 ,  C07C67/29 ,  C07C68/06 ,  C07C69/28 ,  C07C69/618 ,  C07C69/76 ,  C07C69/78 ,  C07C69/92 ,  C07C69/96 ,  C07C249/04 ,  C07C251/38 ,  C07C251/40 ,  C07C303/28 ,  C07C309/66 ,  C07C309/73 ,  C07F7/1804 ,  C07H1/00 ,  C07H7/04 ,  C07H13/04 ,  C07H13/08 ,  C07H15/04 ,  C07H15/18 ,  C07H15/203 ,  C07H17/02 ,  C07H19/06 ,  C07H19/067 ,  C07H19/073 ,  C07H23/00 ,  Y02P20/55

Abstract: A compound represented by a formula [1D] as shown below (wherein R1A, R1B, R2A, R2B, R3A and R3B represent a hydrogen atom, an optionally substituted C1-6 alkyl group, and the like) is useful as an intermediate for producing a thionucleoside, and the production method of the present invention is useful as a method for producing a thionucleoside.

Abstract translation: 由下式（其中R1A，R1B，R2A，R2B，R3A和R3B表示氢原子，任选取代的C 1-6烷基等）表示的由式[1D]表示的化合物可用作生产中间体 硫代核苷，本发明的制造方法可用作硫代核苷的制造方法。