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公开(公告)号：US20180000964A1
公开(公告)日：2018-01-04
申请号：US15618467
申请日：2017-06-09
Applicant: Genentech, Inc.
Inventor： Christine Tan , Ryan J. Watts , Joy Yu Zuchero , Xiaocheng Chen , Mark S. Dennis
CPC classification number: A61K47/6849 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K16/18 , C07K16/26 , C07K16/2803 , C07K16/2896 , C07K16/40 , C07K2317/31 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/92 , C12Y304/23046
Abstract: The present invention relates to antibodies that bind to receptors expressed on the blood brain barrier and methods of using the same.
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公开(公告)号：US20170058049A1
公开(公告)日：2017-03-02
申请号：US15234649
申请日：2016-08-11
Applicant: Genentech, Inc.
Inventor： Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
CPC classification number: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
Abstract translation: 本发明提供了针对特定神经蛋白的抗体及其使用方法。
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公开(公告)号：US08795660B2
公开(公告)日：2014-08-05
申请号：US13740080
申请日：2013-01-11
Applicant: Genentech, Inc.
Inventor： Ryan J. Watts , Yan Wu
IPC: A61K39/395
CPC classification number: C07K16/2863 , A61K31/404 , A61K31/502 , A61K31/506 , A61K31/517 , A61K31/661 , A61K31/69 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K16/22 , C07K16/3023 , C07K2317/31 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications.
Abstract translation: 公开了具有独特结构和功能特征的新型NRP1抗体及其变体。 还提供了抗体在研究，诊断和治疗应用中的用途。
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公开(公告)号：US20130115214A1
公开(公告)日：2013-05-09
申请号：US13740080
申请日：2013-01-11
Applicant: GENENTECH, INC.
Inventor： Ryan J. Watts , Yan WU
IPC: C07K16/28 , A61K31/69 , A61K31/506 , A61K31/517 , A61K31/404 , A61K31/661 , A61K39/395 , A61K31/502
CPC classification number: C07K16/2863 , A61K31/404 , A61K31/502 , A61K31/506 , A61K31/517 , A61K31/661 , A61K31/69 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K16/22 , C07K16/3023 , C07K2317/31 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications.
Abstract translation: 公开了具有独特结构和功能特征的新型NRP1抗体及其变体。 还提供了抗体在研究，诊断和治疗应用中的用途。
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公开(公告)号：US11008403B2
公开(公告)日：2021-05-18
申请号：US15525821
申请日：2015-11-18
Applicant: Genentech, Inc. , Adimab LLC
Inventor： Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus , Yin Zhang , Joy Yu Zuchero , Jessica Couch , Mark S Dennis , James A Ernst , Gregory A Lazar
Abstract: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
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Patent Agency Ranking
公开(公告)号：US10808036B2
公开(公告)日：2020-10-20
申请号：US15614149
申请日：2017-06-05
Applicant: Genentech, Inc.
Inventor： Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S. Dennis , James A. Ernst , Ryan J. Watts , Gregory A. Lazar
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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公开(公告)号：US09937224B2
公开(公告)日：2018-04-10
申请号：US14822711
申请日：2015-08-10
Applicant: Genentech, Inc.
Inventor： Ryan J. Watts , Mark Chen , Joseph Wesley Lewcock , Christine Pozniak , Arundhati Sengupta-Ghosh
IPC: A61K39/395 , A61K33/14 , A61K31/40 , A61K38/12 , A61K31/7088 , A61K31/711 , C12N15/113 , A61K31/7105 , A61K31/277 , A61K31/35 , A61K31/4015 , A61K31/416 , A61K31/4439 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K38/05 , A61K38/18 , C07K16/22 , G01N33/50 , A61K31/12 , A61K31/165 , A61K31/352 , A61K31/4184 , A61K31/426 , A61K31/433 , A61K31/45 , A61K31/496 , A61K31/505 , A61K31/517 , A61K31/519 , A61K31/713 , C07K16/40
CPC classification number: A61K38/12 , A61K31/12 , A61K31/165 , A61K31/277 , A61K31/35 , A61K31/352 , A61K31/40 , A61K31/4015 , A61K31/416 , A61K31/4184 , A61K31/426 , A61K31/433 , A61K31/4439 , A61K31/45 , A61K31/496 , A61K31/505 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/52 , A61K31/5377 , A61K31/7088 , A61K31/7105 , A61K31/711 , A61K31/713 , A61K33/14 , A61K38/05 , A61K38/185 , C07K16/22 , C07K16/40 , C07K2317/76 , C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2320/30 , G01N33/5058
Abstract: The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using modulators of particular target proteins to modulate degeneration of neurons or portions thereof, such as axons.
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公开(公告)号：US20180002433A1
公开(公告)日：2018-01-04
申请号：US15614149
申请日：2017-06-05
Applicant: Genentech, Inc.
Inventor： Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S. Dennis , James A. Ernst , Ryan J. Watts , Gregory A. Lazar
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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公开(公告)号：US09708406B2
公开(公告)日：2017-07-18
申请号：US14283038
申请日：2014-05-20
Applicant: Genentech, Inc.
Inventor： Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S. Dennis , James A. Ernst , Ryan J. Watts , Gregory A. Lazar
CPC classification number: C07K16/2881 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/40 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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公开(公告)号：US09453079B2
公开(公告)日：2016-09-27
申请号：US14292461
申请日：2014-05-30
Applicant: Genentech, Inc.
Inventor： Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
IPC: C07K16/18 , A61K39/395 , C07K16/40 , A61K47/48 , G01N33/573 , A61K39/00
CPC classification number: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
Abstract translation: 本发明提供了针对特定神经蛋白的抗体及其使用方法。
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