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公开(公告)号:US20200285194A1
公开(公告)日:2020-09-10
申请号:US16648987
申请日:2018-09-19
Applicant: IMEC VZW
Inventor: Abdulkadir Yurt , Richard Stahl , Murali Jayapala , Geert Vanmeerbeeck
IPC: G03H1/04
Abstract: Example embodiments relate to imaging devices for in-line holographic imaging of objects. One embodiment includes an imaging device for in-line holographic imaging of an object. The imaging device includes a set of light sources configured to output light in confined illumination cones. The imaging device also includes an image sensor that includes a set of light-detecting elements. The set of light sources are configured to output light such that the confined illumination cones are arranged side-by-side and illuminate a specific part of the object. The image sensor is arranged such that the light-detecting elements detect a plurality of interference patterns. Each interference pattern is formed by diffracted light from the object originating from a single light source and undiffracted light from the same single light source. At least a subset of the set of light-detecting elements is arranged to detect light relating to not more than one interference pattern.
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公开(公告)号:US10126709B2
公开(公告)日:2018-11-13
申请号:US15727832
申请日:2017-10-09
Applicant: IMEC VZW
Inventor: Richard Stahl , Murali Jayapala , Andy Lambrechts , Geert Vanmeerbeeck
Abstract: Embodiments described herein relate to lens-free imaging. One example embodiment may include a lens-free imaging device for imaging a moving sample. The lens-free imaging device may include a radiation source configured to emit a set of at least two different wavelengths towards the moving sample. The lens-free imaging device is configured to image samples for which a spectral response does not substantially vary for a set of at least two different wavelengths. The lens-free imaging device may also include a line scanner configured to obtain a line scan per wavelength emitted by the radiation source and reflected by, scattered by, or transmitted through the moving sample. The line scanner is configured to regularly obtain a line scan per wavelength. Either the radiation source or the line scanner is configured to isolate data of the at least two different wavelengths.
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公开(公告)号:US20180195945A1
公开(公告)日:2018-07-12
申请号:US15738227
申请日:2016-06-28
Applicant: IMEC VZW , Universiteit Gent
Inventor: Bendix Schneider , Peter Bienstman , Joni Dambre , Geert Vanmeerbeeck , Liesbet Lagae
CPC classification number: G01N15/0227 , G01N15/1434 , G01N15/147 , G01N2015/0073 , G01N2015/008 , G01N2015/0233 , G01N2015/1454 , G01N2015/149 , G01N2015/1493 , G03H1/02 , G03H1/0443 , G03H2001/0447 , G03H2226/02 , G03H2226/11
Abstract: A device for extracting at least one object characteristic of an object (106) is presented, the device comprising: a light sensor (101) for recording a hologram of an object and a processing unit (102) coupled to the light sensor and configured for extracting at least one object characteristic from the hologram; wherein the processing unit is configured for extracting the at least one object characteristic from a section of the hologram without reconstructing an image representation of the object. Further, a device (200) for sorting an object (106), a method for identifying an object and a method for sorting objects is presented.
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公开(公告)号:US10697882B2
公开(公告)日:2020-06-30
申请号:US15129267
申请日:2015-04-03
Applicant: IMEC VZW
Inventor: Veerle Reumers , Dries Braeken , Geert Vanmeerbeeck , Richard Stahl , Andy Lambrechts
IPC: G01N33/483 , G01N15/10 , G01N21/47 , G03H1/04 , G01N15/14 , G01N21/45 , G01N21/17 , G01N33/50 , G03H1/00 , G01N15/00
Abstract: The present disclosure relates to devices and methods configured to perform drug screening on cells. At least one embodiment relates to a lens-free device for performing drug screening on cells. The lens-free device includes a substrate having a surface. The lens-free device also includes a light source positioned to illuminate the cells, when present, on the substrate surface with a light wave. The lens-free device further includes a sensor positioned to detect an optical signal caused by illuminating the cells. The substrate surface includes a microelectrode array for sensing an electrophysiological signal from the cells.
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公开(公告)号:US10678187B2
公开(公告)日:2020-06-09
申请号:US15545611
申请日:2016-02-04
Applicant: IMEC VZW
Inventor: Richard Stahl , Tom Claes , Xavier Rottenberg , Geert Vanmeerbeeck , Andy Lambrechts
IPC: H04N5/89 , H04N9/47 , A62B1/04 , G03H1/04 , G02B27/00 , G02B21/00 , G01N15/14 , G02B6/122 , H04N5/225 , H04N13/00 , G02B6/12 , H04N5/374
Abstract: Embodiments described herein relate to a large area lens-free imaging device. One example is a lens-free device for imaging one or more objects. The lens-free device includes a light source positioned for illuminating at least one object. The lens-free device also includes a detector positioned for recording interference patterns of the illuminated at least one object. The light source includes a plurality of light emitters that are positioned and configured to create a controlled light wavefront for performing lens-free imaging.
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公开(公告)号:US20190310584A1
公开(公告)日:2019-10-10
申请号:US16467612
申请日:2017-12-08
Applicant: IMEC VZW
Inventor: Ziduo Lin , Abdulkadir Yurt , Richard Stahl , Geert Vanmeerbeeck
Abstract: Example embodiments relate to methods and imaging systems for holographic imaging. One embodiment includes a method for holographic imaging of an object. The method includes driving a laser using a current which is below a threshold current of the laser. The method also includes illuminating the object using illumination light output by the laser. Further, the method includes detecting an interference pattern formed by object light, having interacted with the object, and reference light of the illumination light.
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公开(公告)号:US20180181062A1
公开(公告)日:2018-06-28
申请号:US15847521
申请日:2017-12-19
Applicant: IMEC vzw
Inventor: Abdulkadir Yurt , Geert Vanmeerbeeck , Richard Stahl , Ziduo Lin
Abstract: An apparatus for in-line holographic imaging is disclosed. In one aspect, the apparatus includes at least a first light source and a second light source arranged for illuminating an object arranged in the apparatus with a light beam. The apparatus also includes an image sensor arranged to detect at least a first and a second interference pattern, wherein the first interference pattern is formed when the object is illuminated by the first light source and the second interference pattern is formed when the object is illuminated by the second light source. The first and second interference patterns are formed by diffracted light, being scattered by the object, and undiffracted light of the light beam. The at least first and second light sources are arranged at different angles in relation to the object, and possibly illuminate the object using different wavelengths.
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公开(公告)号:US20180143079A1
公开(公告)日:2018-05-24
申请号:US15821918
申请日:2017-11-24
Applicant: IMEC VZW
Inventor: Abdulkadir YURT , Ziduo Lin , Richard Stahl , Geert Vanmeerbeeck
IPC: G01J9/02
CPC classification number: G01J9/02 , G01J9/0215 , G01J2009/0223 , G03H1/0443 , G03H1/0465 , G03H2001/0447 , G03H2223/12 , G03H2223/19
Abstract: According to a first aspect, there is provided a method of holographic wavefront sensing, the method including: receiving a light beam, which has a wavefront to be analyzed, on a transparent, flat substrate, which is provided with a lattice of opaque dots, wherein the substrate is arranged above an image sensor; detecting by the image sensor an interference pattern formed by diffracted light, being scattered by the opaque dots, and undiffracted light of the light beam received by the image sensor; processing the detected interference pattern to digitally reconstruct a representation of a displaced lattice of opaque dots, which would form the interference pattern on the image sensor upon receiving the light with a known wavefront; and comparing the representation of the displaced lattice to a known representation of the lattice of opaque dots on the substrate to determine a representation of the wavefront form of the received light beam.
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公开(公告)号:US20170115201A1
公开(公告)日:2017-04-27
申请号:US15129267
申请日:2015-04-03
Applicant: IMEC VZW
Inventor: Veerle Reumers , Dries Braeken , Geert Vanmeerbeeck , Richard Stahl , Andy Lambrechts
Abstract: The present disclosure relates to devices and methods configured to perform drug screening on cells. At least one embodiment relates to a lens-free device for performing drug screening on cells. The lens-free device includes a substrate having a surface. The lens-free device also includes a light source positioned to illuminate the cells, when present, on the substrate surface with a light wave. The lens-free device further includes a sensor positioned to detect an optical signal caused by illuminating the cells. The substrate surface includes a microelectrode array for sensing an electrophysiological signal from the cells.
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公开(公告)号:US11841298B2
公开(公告)日:2023-12-12
申请号:US17127972
申请日:2020-12-18
Applicant: IMEC VZW
Inventor: Ziduo Lin , Abdulkadir Yurt , Richard Stahl , Geert Vanmeerbeeck , Andy Lambrechts
CPC classification number: G01N1/22 , G01N15/0612 , G01N15/1463 , G01N2001/2223 , G01N2001/2276 , G01N2001/2833 , G01N2015/0233
Abstract: The inventive concept relates to a collector for collecting particles in air and a device for detecting particles in air comprising said collector. Said collector comprises a substrate, which is adapted to enable imaging of the particles, an adhesive layer arranged on a collector side of the substrate, said adhesive layer being formed by an adhesive material. The collector further comprises a protection element, which is configured to protect the adhesive layer before collection of particles. The collector is configured to allow release of protection of the adhesive layer by the protection element to expose an adhesive surface of the adhesive layer to ambient air for collecting particles on the adhesive surface. The collector is further configured for presenting a particle sample carrier having a smooth top surface and a smooth bottom surface for preventing light from being diffusely scattered by the particle sample carrier.
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