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22 条记录 (耗时 0.025 秒)

    Preparation of a mechanically durable single layer coating with anti-reflective properties
    11.
    发明申请
    Preparation of a mechanically durable single layer coating with anti-reflective properties 审中-公开
    制备具有抗反射性能的机械耐久的单层涂层

    公开(公告)号：US20090191346A1

    公开(公告)日：2009-07-30

    申请号：US12318594

    申请日：2008-12-31

    申请人： Jens Christoph Thies ,  Edwin Currie ,  Guido Jozefina Wilhelmus Meijers

    发明人： Jens Christoph Thies ,  Edwin Currie ,  Guido Jozefina Wilhelmus Meijers

    IPC分类号： B05D3/00

    CPC分类号： G02B1/111 ,  G02B1/105 ,  G02B1/14 ,  Y10T428/25 ,  Y10T428/252 ,  Y10T428/31971

    摘要： Single layer anti-reflective hard-coat; in particular which comprises a structured surface, preferably a nano-structured surface. The hard-coat preferably a hardness above 0.5 GPa, more preferably above 0.7 GPa and most preferably above 1.0 GPa as measured by nano-indentation and/or a reduced tensile modulus above 3 GPa, more preferably above 8.5 GPa or 20 GPa, most preferably above 40 GPa as measured by nano-indentation and/or a scratch resistance above 5 mJ μm−3, preferably above 15 or 30 mJ μm−3, preferably above 60 mJ μm−3 as measured by nano-indentation, and/or contains an amount of inorganic nano-particles from 5 to 75 weight %, preferably from 15 to 50 weight % relative to the weight of the second material present in the hard-coat.Preferably, the spatial length scale of the refractive index gradient in the single layer hard-coat is between 10 and 1000 nm; in particular between 100 and 200 nm.Also concerned is a process for preparing a single layer hard-coat, comprising the steps ofa) applying a mixture on a substrate, which mixture comprises i. at least a first material which does not crosslink under the conditions chosen in step b) ii. at least a second material which does crosslink under the conditions chosen in step b) iii. nano-particles, and iv. optionally at least one solvent b) inducing crosslinking in the mixture applied to the substrate, v. subsequently removing at least part of the first material, and shaped articles comprising such single layer hard-coat.

    摘要翻译： 单层抗反射硬涂层; 特别地，其包括结构化表面，优选纳米结构化表面。 硬涂层优选硬度高于0.5GPa，更优选高于0.7GPa，最优选高于1.0GPa，通过纳米压痕和/或降低的拉伸模量高于3GPa，更优选高于8.5GPa或20GPa，最优选 和/或通过纳米压痕测量的/或耐擦伤性高于5mJ mum-3，优选高于15或30mJ mum-3，优选高于60mJ mm-3测量的40GPa以上和/或包含 相对于存在于硬涂层中的第二材料的重量，无机纳米颗粒的量为5至75重量％，优选15至50重量％。 优选地，单层硬涂层中的折射率梯度的空间长度尺度在10和1000nm之间; 特别是在100和200nm之间。 还涉及一种制备单层硬涂层的方法，包括以下步骤：a）在基材上施加混合物，该混合物包括： 至少一种在步骤b）ii中选择的条件下不交联的第一种材料。 至少第二种材料，其在步骤b）中选择的条件下进行交联。 纳米颗粒，和iv。 任选地至少一种溶剂b）在施加到基底上的混合物中引起交联，v随后除去至少部分第一材料，以及包含这种单层硬涂层的成型制品。

    FIBER COMPRISING A BIODEGRADABLE POLYMER
    14.
    发明申请
    FIBER COMPRISING A BIODEGRADABLE POLYMER 审中-公开
    包含可生物降解聚合物的纤维

    公开(公告)号：US20140179802A1

    公开(公告)日：2014-06-26

    申请号：US14115146

    申请日：2012-05-02

    申请人： Astrid Franken ,  George Mihov ,  Jens Christoph Thies

    发明人： Astrid Franken ,  George Mihov ,  Jens Christoph Thies

    IPC分类号： A61K9/00 ,  A61K47/34

    CPC分类号： A61K9/0051 ,  A61K9/0019 ,  A61K9/70 ,  A61K47/34 ,  C08G69/44 ,  D01F1/10 ,  D01F6/625 ,  D01F6/82 ,  D10B2331/02 ,  D10B2331/041 ,  D10B2401/12

    摘要： The present invention relates to a fiber comprising a biodegradable polymer which undergoes dimensional change upon injection in the human or animal body wherein the dimensional change is a reduction of the surface area to volume ratio of a factor 2 to 10. The fiber is sized for injection via a pharmaceutical syringe needle having a bore of at least 25 Gauge. The biodegradable polymer is an amorphous biodegradable polymer selected from the group of poly-hexamethylene carbonates or polyesteramides. The amorphous biodegradable polymer is a preferably a polyesteramide comprising alpha-amino acids, diols and dicarboxylic acids as building blocks. The invention further relates to the use of the fiber for the manufacturing of a medicament for the treatment of ophthalmic diseases. The invention also relates to a process for the manufacturing of the fiber comprising the following process steps; a. extruding a biodegradable polymer into a fiber fitting in a needle of at least 25 Gauge b. which while under tension is cooled below its glass transition temperature such that the resultant fiber is amorphous.

    摘要翻译： 本发明涉及一种包含生物可降解聚合物的纤维，其在人或动物体内注射时经历尺寸变化，其中尺寸变化是因子2至10的表面积与体积比的降低。纤维的尺寸用于注射 通过具有至少25度的孔的制药注射器针头。 可生物降解的聚合物是选自聚六亚甲基碳酸酯或聚酯酰胺的无定形可生物降解的聚合物。 无定形可生物降解聚合物优选为包含α-氨基酸，二醇和二羧酸作为结构单元的聚酯酰胺。 本发明还涉及该纤维在制备用于治疗眼科疾病的药物中的用途。 本发明还涉及一种用于制造纤维的方法，包括以下工艺步骤; 一个。 将可生物降解的聚合物挤出到至少25巴的针中的纤维配合物中。 其在张力下被冷却到其玻璃化转变温度以下，使得所得纤维是无定形的。

    IMPROVED ANTI-BIOFOULING COATING
    16.
    发明申请
    IMPROVED ANTI-BIOFOULING COATING 审中-公开
    改进抗生素涂料

    公开(公告)号：US20120135149A1

    公开(公告)日：2012-05-31

    申请号：US13257850

    申请日：2010-03-25

    申请人： Pascal Josef Paul Buskens ,  Jacobus Adriaan Antonius Vermeulen ,  Ronnie de Rijk ,  Jens Christoph Thies ,  Jun Qiu

    发明人： Pascal Josef Paul Buskens ,  Jacobus Adriaan Antonius Vermeulen ,  Ronnie de Rijk ,  Jens Christoph Thies ,  Jun Qiu

    IPC分类号： B05D5/00 ,  C09D5/16

    CPC分类号： C08F283/12 ,  C08F291/00 ,  C08J7/047 ,  C08L51/003 ,  C08L51/085 ,  C09D5/1637 ,  C09D151/003 ,  C09D151/085 ,  C09D201/005 ,  C08L2666/02

    摘要： The invention relates to a coating material suitable for providing a substrate with an anti-biofouling coating, the coating material comprising a macromolecule comprising: (A) a macromolecular scaffold comprising a reactive group capable of undergoing a Michael type reaction between a Michael type acceptor group and a Michael type donor group, (B) at least one functional moiety attached to the macromolecular scaffold, said at least one functional moiety comprising a hydrophilic moiety, wherein the functional moiety is derivable from a Michael type reaction, involving the reactive group on the macromolecular scaffold and a reactive hydrophilic moiety and (C) at least one moiety capable of crosslinking the coating material.

    摘要翻译： 本发明涉及一种适用于提供具有抗生物污损涂层的基材的涂层材料，所述涂层材料包含大分子，其包含：（A）大分子支架，其包含能够在迈克尔型受体基团之间经历迈克尔型反应的反应性基团 和（B）至少一个与大分子支架连接的功能部分，所述至少一个功能部分包含亲水部分，其中所述功能部分可衍生自迈克尔型反应，涉及所述反应性基团 大分子支架和反应性亲水部分和（C）能够交联涂层材料的至少一个部分。

    HIGH PERFORMANCE MEMBRANE
    19.
    发明申请
    HIGH PERFORMANCE MEMBRANE 有权
    高性能膜

    公开(公告)号：US20100305217A1

    公开(公告)日：2010-12-02

    申请号：US12743089

    申请日：2008-11-14

    申请人： Jun Qiu ,  Rudy Rulkens ,  Johannes Leornardus Maria OP Den Kamp ,  Jens Christoph Thies

    发明人： Jun Qiu ,  Rudy Rulkens ,  Johannes Leornardus Maria OP Den Kamp ,  Jens Christoph Thies

    IPC分类号： B01D69/12 ,  B01D67/00 ,  B01D65/00 ,  B01D71/06 ,  C12N11/08 ,  A61K47/30

    CPC分类号： B01D67/0088 ,  B01D69/02 ,  B01D71/26 ,  B01D71/56 ,  B01D2323/02 ,  B01D2325/22 ,  B01D2325/24 ,  H01M2/145 ,  H01M2/1653

    摘要： The invention relates to a micro-porous membrane comprising a porous membrane carrier made of a first polymeric material (A) and comprising a second polymeric material (B) intimately divided throughout the porous membrane carrier, wherein the porous membrane carrier comprises a plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae having a thickness of less than 1 μm, the porous membrane carrier has an interconnected open porous structure formed by the plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae and a porosity of at least 50%; and the polymeric material (B) comprises a thermoplastic polycondensation polymer and is present in an amount of at most 30 wt. %, relative to the total weight of (A) and (B). The invention also relates to a process for preparing such a micro-porous membrane comprising steps wherein (i) a porous membrane carrier made of a first polymeric material (A) is impregnated with a polymer solution comprising a second polymeric material (B) in a solvent system (X), and (ii) the resulting impregnated membrane carrier is quenched in a non-solvent system (Y), thereby precipitating at least part of the second polymeric material (B).

    摘要翻译： 本发明涉及一种微孔膜，其包括由第一聚合物材料（A）制成的多孔膜载体，并且包括在整个多孔膜载体上密切分配的第二聚合材料（B），其中多孔膜载体包括多个互连的 聚合物纤维，原纤维，细丝和/或薄片，厚度小于1μm，多孔膜载体具有由多个互连的聚合物纤维，原纤维，长丝和/或薄片形成的互连的开放多孔结构， 至少50％; 聚合物材料（B）包含热塑性缩聚聚合物，其含量至多为30wt。 ％，相对于（A）和（B）的总重量。 本发明还涉及一种制备这种微孔膜的方法，其包括以下步骤：（i）由第一聚合物材料（A）制成的多孔膜载体用包含第二聚合物材料（B）的聚合物溶液浸渍 溶剂体系（X），和（ii）所得浸渍的膜载体在非溶剂系统（Y）中骤冷，从而沉淀至少部分第二聚合物材料（B）。