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    HIGH PERFORMANCE MEMBRANE
    1.
    发明申请
    HIGH PERFORMANCE MEMBRANE 有权
    高性能膜

    公开(公告)号：US20100305217A1

    公开(公告)日：2010-12-02

    申请号：US12743089

    申请日：2008-11-14

    申请人： Jun Qiu ,  Rudy Rulkens ,  Johannes Leornardus Maria OP Den Kamp ,  Jens Christoph Thies

    发明人： Jun Qiu ,  Rudy Rulkens ,  Johannes Leornardus Maria OP Den Kamp ,  Jens Christoph Thies

    IPC分类号： B01D69/12 ,  B01D67/00 ,  B01D65/00 ,  B01D71/06 ,  C12N11/08 ,  A61K47/30

    CPC分类号： B01D67/0088 ,  B01D69/02 ,  B01D71/26 ,  B01D71/56 ,  B01D2323/02 ,  B01D2325/22 ,  B01D2325/24 ,  H01M2/145 ,  H01M2/1653

    摘要： The invention relates to a micro-porous membrane comprising a porous membrane carrier made of a first polymeric material (A) and comprising a second polymeric material (B) intimately divided throughout the porous membrane carrier, wherein the porous membrane carrier comprises a plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae having a thickness of less than 1 μm, the porous membrane carrier has an interconnected open porous structure formed by the plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae and a porosity of at least 50%; and the polymeric material (B) comprises a thermoplastic polycondensation polymer and is present in an amount of at most 30 wt. %, relative to the total weight of (A) and (B). The invention also relates to a process for preparing such a micro-porous membrane comprising steps wherein (i) a porous membrane carrier made of a first polymeric material (A) is impregnated with a polymer solution comprising a second polymeric material (B) in a solvent system (X), and (ii) the resulting impregnated membrane carrier is quenched in a non-solvent system (Y), thereby precipitating at least part of the second polymeric material (B).

    摘要翻译： 本发明涉及一种微孔膜，其包括由第一聚合物材料（A）制成的多孔膜载体，并且包括在整个多孔膜载体上密切分配的第二聚合材料（B），其中多孔膜载体包括多个互连的 聚合物纤维，原纤维，细丝和/或薄片，厚度小于1μm，多孔膜载体具有由多个互连的聚合物纤维，原纤维，长丝和/或薄片形成的互连的开放多孔结构， 至少50％; 聚合物材料（B）包含热塑性缩聚聚合物，其含量至多为30wt。 ％，相对于（A）和（B）的总重量。 本发明还涉及一种制备这种微孔膜的方法，其包括以下步骤：（i）由第一聚合物材料（A）制成的多孔膜载体用包含第二聚合物材料（B）的聚合物溶液浸渍 溶剂体系（X），和（ii）所得浸渍的膜载体在非溶剂系统（Y）中骤冷，从而沉淀至少部分第二聚合物材料（B）。

    IMPROVED ANTI-BIOFOULING COATING
    4.
    发明申请
    IMPROVED ANTI-BIOFOULING COATING 审中-公开
    改进抗生素涂料

    公开(公告)号：US20120135149A1

    公开(公告)日：2012-05-31

    申请号：US13257850

    申请日：2010-03-25

    申请人： Pascal Josef Paul Buskens ,  Jacobus Adriaan Antonius Vermeulen ,  Ronnie de Rijk ,  Jens Christoph Thies ,  Jun Qiu

    发明人： Pascal Josef Paul Buskens ,  Jacobus Adriaan Antonius Vermeulen ,  Ronnie de Rijk ,  Jens Christoph Thies ,  Jun Qiu

    IPC分类号： B05D5/00 ,  C09D5/16

    CPC分类号： C08F283/12 ,  C08F291/00 ,  C08J7/047 ,  C08L51/003 ,  C08L51/085 ,  C09D5/1637 ,  C09D151/003 ,  C09D151/085 ,  C09D201/005 ,  C08L2666/02

    摘要： The invention relates to a coating material suitable for providing a substrate with an anti-biofouling coating, the coating material comprising a macromolecule comprising: (A) a macromolecular scaffold comprising a reactive group capable of undergoing a Michael type reaction between a Michael type acceptor group and a Michael type donor group, (B) at least one functional moiety attached to the macromolecular scaffold, said at least one functional moiety comprising a hydrophilic moiety, wherein the functional moiety is derivable from a Michael type reaction, involving the reactive group on the macromolecular scaffold and a reactive hydrophilic moiety and (C) at least one moiety capable of crosslinking the coating material.

    摘要翻译： 本发明涉及一种适用于提供具有抗生物污损涂层的基材的涂层材料，所述涂层材料包含大分子，其包含：（A）大分子支架，其包含能够在迈克尔型受体基团之间经历迈克尔型反应的反应性基团 和（B）至少一个与大分子支架连接的功能部分，所述至少一个功能部分包含亲水部分，其中所述功能部分可衍生自迈克尔型反应，涉及所述反应性基团 大分子支架和反应性亲水部分和（C）能够交联涂层材料的至少一个部分。

    Highly porous polymeric materials comprising biologically active molecules via covalent grafting
    8.
    发明申请
    Highly porous polymeric materials comprising biologically active molecules via covalent grafting 审中-公开
    通过共价接枝包含生物活性分子的高度多孔的聚合物材料

    公开(公告)号：US20090215913A1

    公开(公告)日：2009-08-27

    申请号：US11918777

    申请日：2006-04-21

    申请人： Jens Christoph Thies ,  Sebastien Pierre ,  Neil Ronald Cameron

    发明人： Jens Christoph Thies ,  Sebastien Pierre ,  Neil Ronald Cameron

    IPC分类号： C08J9/36 ,  C08J9/00

    CPC分类号： C12N11/06 ,  C12N11/08

    摘要： The present invention relates to highly porous polymeric materials comprising covalently grafted biologically active species. The invention also relates to a process for the preparation of highly porous materials comprising functional monomers capable of grafting to a biologically active molecular species comprising the steps of: (a) preparing an emulsion composition comprising a droplet phase and a continuous phase and containing monomers, (b) curing the emulsion and (c) optionally removing the water/droplet phase. The invention further relates to a process for grafting biologically active species to such a highly porous polymeric material comprising the steps of: (i) exposing the highly porous material to a solution of the biologically active species in a suitable solvent medium, (ii) optionally adding an activating agent, (iii) optionally heating, and (iv) rinsing the porous material with solvent medium to remove non-grafted species. The highly porous polymeric materials comprising covalently grafted biologically active species can be used e.g. as a heterogeneous catalyst, in biosensors, for chromatography, in biomedical devices and in implants.

    摘要翻译： 本发明涉及包含共价接枝的生物活性物质的高度多孔的聚合物材料。 本发明还涉及一种制备包含能够接枝到生物活性分子物质的官能单体的高度多孔材料的方法，包括以下步骤：（a）制备包含液滴相和连续相并含有单体的乳液组合物， （b）固化乳液和（c）任选地除去水/液滴相。 本发明还涉及将生物活性物质接枝到这种高度多孔的聚合物材料的方法，包括以下步骤：（i）将高度多孔的材料暴露于生物活性物质在合适的溶剂介质中的溶液，（ii）任选地 加入活化剂，（iii）任选地加热，和（iv）用溶剂介质漂洗多孔材料以除去未接枝的物质。 包含共价接枝的生物活性物质的高度多孔的聚合物材料可以例如使用。 作为非均相催化剂，生物传感器，色谱法，生物医学装置和植入物。