公开(公告)号：US20140276251A1

公开(公告)日：2014-09-18

申请号：US14252644

申请日：2014-04-14

Applicant: KCI Licensing, Inc.

Inventor： Larry D. Swain ,  Michael E. Manwaring ,  Douglas A. Cornet ,  Braden King-Fung Leung

IPC: A61F13/00 ,  A61N5/06 ,  A61F2/28 ,  A61M37/00

CPC classification number: A61F13/00068 ,  A61B17/88 ,  A61F2/2846 ,  A61F13/00063 ,  A61F2002/2835 ,  A61F2002/30784 ,  A61F2002/368 ,  A61F2013/00357 ,  A61F2013/00927 ,  A61K38/18 ,  A61K38/19 ,  A61K38/22 ,  A61K49/223 ,  A61M1/0023 ,  A61M1/0088 ,  A61M27/00 ,  A61M37/00 ,  A61M37/0092 ,  A61N5/062

Abstract: Provided is an apparatus that includes a scaffold with a gel or liquid composition deposed on at least a portion of a luminal surface, the gel or liquid composition adapted to include microbubbles. Also provided is a system that includes a source of reduced pressure, the above scaffold, a manifold adjacent the scaffold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure. Additionally provided is a method that includes implanting the above scaffold at the tissue site and disrupting a substantial portion of the microbubbles to induce fluid flow to the scaffold. Further provided is an apparatus that includes a scaffold that comprises a slowly degradable material and a quickly degradable material. Additionally provided is a system for coupling nerve tissue and a microchip assembly.

Abstract translation: 提供了一种装置，其包括具有凝胶或液体组合物的支架，所述支架沉积在腔表面的至少一部分上，所述凝胶或液体组合物适于包含微泡。 还提供了一种包括减压源的系统，上述支架，邻近支架的歧管和用于在歧管和减压源之间提供流体连通的导管。 另外提供了一种方法，其包括将上述支架植入组织部位并破坏大部分微泡以诱导流体流入支架。 还提供了一种装置，其包括包含缓慢降解材料和快速可降解材料的支架。 另外提供了一种用于联接神经组织和微芯片组件的系统。

公开(公告)号：US10398621B2

公开(公告)日：2019-09-03

申请号：US14854957

申请日：2015-09-15

Applicant: KCI Licensing, Inc.

Inventor： Royce W. Johnson ,  Larry D. Swain ,  Douglas A. Cornet ,  Michael Manwaring ,  Jonathan Kagan

IPC: A61F2/02 ,  A61F2/28 ,  A61F2/32 ,  A61M27/00 ,  A61H9/00 ,  A61B17/88 ,  A61F2/36 ,  A61M1/00 ,  A61M37/00 ,  A61F2/00 ,  A61L31/14 ,  A61M5/14 ,  A61F13/02 ,  A61F13/00 ,  A61F2/30 ,  A61B17/12 ,  A61M25/10 ,  A61B17/135 ,  A61B17/80

Abstract: A reduced pressure delivery system for applying reduced pressure tissue treatment to a tissue site is provided. The system includes a manifold delivery tube and a balloon having an inner space. The balloon is capable of assuming collapsed and expanded positions. The system further includes a manifold having a plurality of flow channels. The manifold is disposed within the inner space of the balloon. A sharp tip is configured to be delivered within the manifold delivery tube to puncture the balloon.

公开(公告)号：US20140343689A1

公开(公告)日：2014-11-20

申请号：US14289465

申请日：2014-05-28

Applicant: KCI Licensing, Inc.

Inventor： Royce W. Johnson ,  Archel A. Ambrosio ,  Larry D. Swain ,  Joanna Payne

IPC: A61M1/00 ,  A61M5/14 ,  A61L31/14 ,  A61F2/00

CPC classification number: A61H9/005 ,  A61B17/12168 ,  A61B17/12181 ,  A61B17/12186 ,  A61B17/1219 ,  A61B17/12195 ,  A61B17/1355 ,  A61B17/80 ,  A61B17/88 ,  A61F2/0077 ,  A61F2/30767 ,  A61F2/36 ,  A61F2/3662 ,  A61F13/00068 ,  A61F13/0216 ,  A61F2002/0086 ,  A61F2002/30677 ,  A61F2002/3068 ,  A61F2002/30785 ,  A61F2002/30787 ,  A61F2002/30968 ,  A61F2002/3611 ,  A61F2002/3625 ,  A61F2002/368 ,  A61F2002/3694 ,  A61F2310/00395 ,  A61F2310/00592 ,  A61F2310/00928 ,  A61H2201/0103 ,  A61L31/146 ,  A61M1/0023 ,  A61M1/0037 ,  A61M1/0084 ,  A61M1/0088 ,  A61M1/0092 ,  A61M5/14 ,  A61M27/00 ,  A61M37/00 ,  A61M2025/1086

Abstract: A reduced pressure delivery system for applying a reduced pressure to a tissue site includes a manifold delivery tube having a passageway and a distal end, the distal end configured to be percutaneously inserted and placed adjacent the tissue site. A flowable material is provided and is percutaneously deliverable through the manifold delivery tube to the tissue site. The flowable material is capable of filling a void adjacent the tissue site to create a manifold having a plurality of flow channels in fluid communication with the tissue site. A reduced pressure delivery tube is provided that is capable of fluid communication with the flow channels of the manifold.

Abstract translation: 用于向组织部位施加减压的减压递送系统包括具有通道和远端的歧管输送管，所述远端构造成经皮插入并放置在组织部位附近。 提供可流动的材料并经由歧管输送管经皮递送至组织部位。 可流动材料能够填充邻近组织部位的空隙，以产生具有与组织部位流体连通的多个流动通道的歧管。 提供了能够与歧管的流动通道流体连通的减压输送管。

公开(公告)号：US20140094928A1

公开(公告)日：2014-04-03

申请号：US14098195

申请日：2013-12-05

Applicant: KCI Licensing, Inc.

Inventor： Larry D. Swain ,  Michael E. Manwaring ,  Douglas A. Cornet ,  Braden K. Leung

IPC: A61F2/28 ,  A61L27/54

CPC classification number: A61F2/28 ,  A61F2002/2817 ,  A61F2002/4685 ,  A61L27/54 ,  A61M1/0031 ,  A61M1/0035 ,  A61M1/0088 ,  A61M5/16881 ,  A61M27/00 ,  A61M39/22 ,  A61M2205/3334

Abstract: Provided are apparatuses, systems, and methods for treating tissue at a tissue site in a mammal that includes a scaffold adapted to be disposed adjacent to the tissue site and to be fluidly coupled to a blood vessel of the mammal for receiving blood therefrom. Additionally, a scaffold is provided that includes a charged surface comprising a streaming potential.

Abstract translation: 提供了用于在哺乳动物的组织部位处理组织的装置，系统和方法，所述装置，系统和方法包括适于邻近所述组织部位设置并与所述哺乳动物的血管流体耦合以从其接收血液的支架。 另外，提供了一种支架，其包括包含流动电位的带电表面。