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111 条记录 (耗时 0.093 秒)

    Method of inhibiting formation of volatile aldehydes and/or decomposition of fatty acids and use thereof
    12.
    发明授权
    Method of inhibiting formation of volatile aldehydes and/or decomposition of fatty acids and use thereof 有权
    抑制挥发性醛形成和/或分解脂肪酸的方法及其用途

    公开(公告)号：US08642575B2

    公开(公告)日：2014-02-04

    申请号：US10545078

    申请日：2004-02-10

    申请人： Kazuyuki Oku ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Kazuyuki Oku ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： A01N43/04 ,  A61K31/715

    CPC分类号： A23L3/3562 ,  A23L2/60 ,  A23L5/27 ,  A23L27/33 ,  A61K8/60 ,  A61K8/73 ,  A61K9/0014 ,  A61K9/0019 ,  A61K47/26 ,  A61K2800/52 ,  A61Q19/00 ,  C11B5/0021

    摘要： The present invention has objects to provide a method for inhibiting the formation of volatile aldehydes and/or the decomposition of fatty acids and use thereof. These objects are attained by establishing a method which comprises incorporating an α-oligoglucosyl α,α-trehalose(s) to a target product to inhibit the formation of volatile aldehydes per se and/or the decomposition of fatty acids per se in fatty acid-containing products; an inhibitory agent for inhibiting the formation of volatile aldehydes and/or the decomposition of fatty acids, which contains an α-oligoglucosyl α,α-trehalose(s) as an effective ingredient; and use thereof to thereby obtain various compositions such as food products, cosmetics, pharmaceuticals, and their materials and intermediates each having a high quality and stability.

    摘要翻译： 本发明的目的是提供抑制挥发性醛形成和/或脂肪酸分解的方法及其用途。 这些目的通过建立一种方法来实现，该方法包括将α-低聚葡萄糖基α，α-海藻糖掺入目标产物以抑制挥发性醛本身的形成和/或脂肪酸 - 含有产品; 用于抑制挥发性醛形成和/或脂肪酸分解的抑制剂，其含有α-低聚葡萄糖基α，α-海藻糖作为有效成分; 并使用它们，从而获得各种具有高质量和稳定性的各种组合物，例如食品，化妆品，药​​物及其材料和中间体。

    Process for producing isomaltose and uses thereof
    13.
    发明授权
    Process for producing isomaltose and uses thereof 有权
    异麦芽糖的制备方法及其用途

    公开(公告)号：US07709230B2

    公开(公告)日：2010-05-04

    申请号：US11777044

    申请日：2007-07-12

    申请人： Michio Kubota ,  Tomoyuki Nishimoto ,  Takanobu Higashiyama ,  Hikaru Watanabe ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Michio Kubota ,  Tomoyuki Nishimoto ,  Takanobu Higashiyama ,  Hikaru Watanabe ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： C12P19/44 ,  C12P19/18 ,  C12P19/04 ,  C12N9/00 ,  C12N9/10 ,  C12P21/06 ,  C07H1/00

    CPC分类号： C12P19/12

    摘要： A novel process for producing isomaltose and uses thereof and comprising the steps of contacting saccharides, which have a glucose polymerization degree of at least two and α-1,4 glucosidic linkage as a linkage at the non-reducing end, with an α-isomaltosylglucosaccharide-forming enzyme, in the presence or the absence of α-isomaltosyl-transferring enzyme to form a-isomaltosylglucosaccharides, which have a glucose polymerization degree of at least three, α-1,6 glucosidic linkage as a linkage at the non-reducing end, and α-1,4 glucosidic linkage as a linkage other than the non-reducing end, and/or to form cyclo{→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→}; contacting the saccharides so formed with isomaltose-releasing enzyme to release isomaltose; and collecting the released isomaltose; and uses thereof.

    摘要翻译： 一种生产异麦芽糖的新方法及其应用，包括以下步骤：将非还原末端具有至少两个葡萄糖聚合度和至少两个α-1,4糖苷键作为键的糖与α-异麦芽糖基葡萄糖 在α-异麦芽糖基转移酶的存在或不存在下形成α-异麦芽糖基葡糖，其在非还原末端具有至少三个α-1,6糖苷键作为键的葡萄糖聚合度 和α-1,4糖苷键作为非还原端以外的键，和/或形成环{→6）-α-D-吡喃葡萄糖基 - （1→3）-α-D-吡喃葡萄糖基 - （ 1→6）-α-D-吡喃葡萄糖基 - （1→3）-α-D-吡喃葡萄糖基 - （1→};使与异麦芽糖释放酶形成的糖接触释放异麦芽糖;收集释放的异麦芽糖; 其中。

    Processes for producing isomaltose and isomaltitol and use thereof
    14.
    发明授权
    Processes for producing isomaltose and isomaltitol and use thereof 有权
    制备异麦芽糖和异麦芽糖醇的方法及其用途

    公开(公告)号：US07592160B2

    公开(公告)日：2009-09-22

    申请号：US10492932

    申请日：2002-10-18

    申请人： Michio Kubota ,  Tomoyuki Nishimoto ,  Tomohiko Sonoda ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Michio Kubota ,  Tomoyuki Nishimoto ,  Tomohiko Sonoda ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： C12P19/44

    CPC分类号： C12P19/12

    摘要： The present invention aims to provide a novel process for producing isomaltose and isomaltitol, and uses thereof, and it solves the object by establishing a process for producing isomaltose comprising a step of contacting a saccharide, having the α-1,4 glucosidic linkage as the linkage of non-reducing end and a glucose polymerization degree of at least two, with an α-isomaltosyl-transferring enzyme and an α-isomaltosylglucosaccharide-forming enzyme derived from a specific microorganism; a process for producing isomaltitol using the isomaltose produced by the above process; saccharide compositions comprising the isomaltose and/or the isomaltitol produced by the above processes; and uses thereof.

    摘要翻译： 本发明的目的在于提供一种制备异麦芽糖和异麦芽糖醇的新方法及其用途，其通过建立异麦芽糖的制备方法来解决该问题，该方法包括使具有α-1,4糖苷键的糖类作为 非还原末端与葡萄糖聚合度至少为2的α-异麦芽糖基转移酶和源自特异性微生物的α-异麦芽糖基葡萄糖形成酶的连接; 使用由上述方法生产的异麦芽糖制备异麦芽糖醇的方法; 包含通过上述方法生产的异麦芽糖和/或异麦芽糖醇的糖组合物; 及其用途。

    Skin preparation for external use characterized by containing sugar derivative of alpha, alpha-trehalose
    16.
    发明申请
    Skin preparation for external use characterized by containing sugar derivative of alpha, alpha-trehalose 有权
    外用皮肤制剂，其特征在于含有α，α-海藻糖的糖衍生物

    公开(公告)号：US20070003502A1

    公开(公告)日：2007-01-04

    申请号：US10545166

    申请日：2004-02-10

    申请人： Fujimi Tanabe ,  Michio Kubota ,  Hiromi Tatsukawa ,  Shigeru Fukuda ,  Toshio Miyake

    发明人： Fujimi Tanabe ,  Michio Kubota ,  Hiromi Tatsukawa ,  Shigeru Fukuda ,  Toshio Miyake

    IPC分类号： A61K31/7048 ,  A61K31/704 ,  A61K31/7012 ,  A61K8/73

    CPC分类号： A61Q19/02 ,  A61K8/0212 ,  A61K8/60 ,  A61K9/0014 ,  A61K31/702 ,  A61K31/716 ,  A61K45/06 ,  A61K47/26 ,  A61K2800/522 ,  A61Q1/02 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q7/00 ,  A61Q11/00 ,  A61Q17/005 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  A61Q19/10 ,  A61K2300/00

    摘要： The present invention has an object to provide an external dermatological formulation having satisfactory blood flow-promoting effect, antiinflammatory effect, antibacterial effect, moisturizing effect, whitening effect, UV-absorbing effect, UV-scattering effect, antioxidant effect, hair growing effect, hair nourishing effect, emusifying effect, astringent effect, wrinkle-reducing effect, cell-activating effect and/or transdermal absorption-promoting effect with a satisfactory safety and skin feeling; The object is solved by providing an external dermatological formulation comprising a saccharide derivative of α,α-trehalose and one or more members selected from substances having any one of blood flow-promoting effect, antiinflammatory effect, antibacterial effect, moisturizing effect, whitening effect, UV-absorbing effect, UV-scattering effect, antioxidant effect, hair growing efect, hair nourishing effect, emulsifying effect, astringent effect, wrinkle-reducing effect, cell-activating effect and transdermal absorption-promoting effect.

    摘要翻译： 本发明的目的是提供具有令人满意的血液促进作用，抗炎作用，抗菌作用，保湿效果，美白效果，紫外线吸收效果，紫外线散射效果，抗氧化作用，发丝效果，毛发 滋养效果，呕吐效果，皱纹减轻效果，细胞活化作用和/或透皮吸收促进作用，具有令人满意的安全性和皮肤感觉; 通过提供包含α，α-海藻糖的糖衍生物和一种或多种选自具有血流促进作用，抗炎作用，抗菌作用，保湿作用，美白效果，任何一种的物质的外部皮肤病学制剂来解决该问题， 紫外线吸收效果，紫外线散射效果，抗氧化作用，毛发生长效果，滋养滋养效果，乳化作用，收敛效果，皱纹减轻效果，细胞活化作用和透皮吸收促进作用。

    Process for producing 2-0-alpha-d-glucopyranosyl-l-ascorbic acid
    17.
    发明申请
    Process for producing 2-0-alpha-d-glucopyranosyl-l-ascorbic acid 有权
    制备2-0-α-d-吡喃葡萄糖基-1-抗坏血酸的方法

    公开(公告)号：US20060216792A1

    公开(公告)日：2006-09-28

    申请号：US10523920

    申请日：2003-07-07

    申请人： Kazuhisa Mukai ,  Keiji Tsusaki ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Kazuhisa Mukai ,  Keiji Tsusaki ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： C12P19/44

    CPC分类号： C12P19/60

    摘要： The object of the present invention is to provide a method and a process for producing 2-O-α-glucopyranosyl-L-ascorbic acid where 5-O-α-glucopyranosyl-L-ascorbic acid and 6-O-α-glucopyranosyl-L-ascorbic acid are not formed or formed in such a small amount that the formation of these can nor be detected. The present invention solves the above object by providing a process for producing 2-O-α-glucopyranosyl-L-ascorbic acid comprising the steps of allowing α-isomaltosyl glucosaccharide-forming enzyme together with or without cyclomaltodextrin glucanotransferase (EC 2.4.1.19) to act on a solution comprising L-ascorbic acid and, an α-glucosyl saccharide to form 2-O-α-glucopyranosyl-L-ascorbic acid and collecting the formed 2-O-α-glucopyranosyl-L-ascorbic acid.

    摘要翻译： 本发明的目的是提供一种生产2-O-α-glucopyranosyl-L-抗坏血酸的方法和方法，其中5-O-α-吡喃葡萄糖基-L-抗坏血酸和6-O-α-吡喃葡萄糖基-L- L-抗坏血酸不是以这样的少量形成或形成，也可以不形成。 本发明通过提供一种生产2-O-α-吡喃葡萄糖基-L-抗坏血酸的方法来解决上述目的，其包括以下步骤：将α-异麦芽糖基糖糖形成酶与或不与环糊精葡聚糖转移酶（EC 2.4.1.19）一起使用 作用于包含L-抗坏血酸和α-葡糖基糖的溶液以形成2-O-α-吡喃葡萄糖基-L-抗坏血酸并收集形成的2-O-α-吡喃葡萄糖基-L-抗坏血酸。

    Kojibiose phosphorylase glucosyl-saccharides produced by transglycosylation
    20.
    发明授权
    Kojibiose phosphorylase glucosyl-saccharides produced by transglycosylation 有权
    通过转糖基化产生的糖基二糖磷酸化葡糖基糖

    公开(公告)号：US06204377B1

    公开(公告)日：2001-03-20

    申请号：US09281259

    申请日：1999-03-30

    申请人： Tomoyuki Nishimoto ,  Michio Kubota ,  Hiroto Chaen ,  Toshio Miyake

    发明人： Tomoyuki Nishimoto ,  Michio Kubota ,  Hiroto Chaen ,  Toshio Miyake

    IPC分类号： C07H100

    CPC分类号： A61K8/60 ,  A61K38/00 ,  A61Q11/00 ,  A61Q17/04 ,  A61Q19/02 ,  C12N9/1051 ,  C12P19/18

    摘要： A kojibiose phosphorylase which hydrolyzes kojibiose in the presence of an inorganic phosphoric acid to form D-glucose and &bgr;-D-glucose-1-phosphoric acid, forms kojibiose and an inorganic phosphoric acid from &bgr;-D-glucose-1-phosphoric acid, and catalyzes the transfer reaction of glucosyl group to other saccharides using &bgr;-D-glucose-1-phosphoric acid as a saccharide donor. The enzyme is obtainable from natural sources such as microorganisms of the genus Thermoanaerobium, and obtainable by recombinant technology. Kojibiose phosphorylase is used to transfer glucose from glucose-1-phosphate to acceptor saccharides to produce &agr;-D-glucosyl-1(1→5)-L-sorbose, kojibiosylglucose, kojibiosylglucoside and kojibiosylfructoside.

    摘要翻译： 在无机磷酸存在下水解曲霉糖以形成D-葡萄糖和β-D-葡萄糖-1-磷酸的曲霉糖磷酸化酶，从β-D-葡萄糖-1-磷酸形成曲酸和无机磷酸， 并使用β-D-葡萄糖-1-磷酸作为糖供体催化葡糖基转移至其他糖类。 该酶可从天然来源例如Thermoanaerobium属的微生物获得，可通过重组技术获得。 葡萄糖磷酸化酶用于将葡萄糖从葡萄糖-1-磷酸转移到受体糖以产生α-D-葡糖基-1（1-> 5）-L-山梨糖，茉莉基糖基葡萄糖，猕猴糖基葡萄糖苷和猕猴桃糖苷果糖苷。