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    Kojibiose phosphorylase glucosyl-saccharides produced by transglycosylation
    2.
    发明授权
    Kojibiose phosphorylase glucosyl-saccharides produced by transglycosylation 有权
    通过转糖基化产生的糖基二糖磷酸化葡糖基糖

    公开(公告)号：US06204377B1

    公开(公告)日：2001-03-20

    申请号：US09281259

    申请日：1999-03-30

    申请人： Tomoyuki Nishimoto ,  Michio Kubota ,  Hiroto Chaen ,  Toshio Miyake

    发明人： Tomoyuki Nishimoto ,  Michio Kubota ,  Hiroto Chaen ,  Toshio Miyake

    IPC分类号： C07H100

    CPC分类号： A61K8/60 ,  A61K38/00 ,  A61Q11/00 ,  A61Q17/04 ,  A61Q19/02 ,  C12N9/1051 ,  C12P19/18

    摘要： A kojibiose phosphorylase which hydrolyzes kojibiose in the presence of an inorganic phosphoric acid to form D-glucose and &bgr;-D-glucose-1-phosphoric acid, forms kojibiose and an inorganic phosphoric acid from &bgr;-D-glucose-1-phosphoric acid, and catalyzes the transfer reaction of glucosyl group to other saccharides using &bgr;-D-glucose-1-phosphoric acid as a saccharide donor. The enzyme is obtainable from natural sources such as microorganisms of the genus Thermoanaerobium, and obtainable by recombinant technology. Kojibiose phosphorylase is used to transfer glucose from glucose-1-phosphate to acceptor saccharides to produce &agr;-D-glucosyl-1(1→5)-L-sorbose, kojibiosylglucose, kojibiosylglucoside and kojibiosylfructoside.

    摘要翻译： 在无机磷酸存在下水解曲霉糖以形成D-葡萄糖和β-D-葡萄糖-1-磷酸的曲霉糖磷酸化酶，从β-D-葡萄糖-1-磷酸形成曲酸和无机磷酸， 并使用β-D-葡萄糖-1-磷酸作为糖供体催化葡糖基转移至其他糖类。 该酶可从天然来源例如Thermoanaerobium属的微生物获得，可通过重组技术获得。 葡萄糖磷酸化酶用于将葡萄糖从葡萄糖-1-磷酸转移到受体糖以产生α-D-葡糖基-1（1-> 5）-L-山梨糖，茉莉基糖基葡萄糖，猕猴糖基葡萄糖苷和猕猴桃糖苷果糖苷。

    Non-reducing saccharides, their preparations and uses
    7.
    发明授权
    Non-reducing saccharides, their preparations and uses 失效
    非还原糖，其制备和用途

    公开(公告)号：US5883243A

    公开(公告)日：1999-03-16

    申请号：US797248

    申请日：1997-02-07

    申请人： Tomoyuki Nishimoto ,  Hiroto Chaen ,  Toshiyuki Sugimoto ,  Toshio Miyake

    发明人： Tomoyuki Nishimoto ,  Hiroto Chaen ,  Toshiyuki Sugimoto ,  Toshio Miyake

    IPC分类号： C07H3/06 ,  C12P19/04 ,  C07H1/00 ,  C12P19/00

    CPC分类号： C07H3/06 ,  C12P19/04

    摘要： .alpha.-Isomaltosyl .alpha.-isomaltoside represented by O-.alpha.-D-glucopyranosyl-(1.fwdarw.6)-.alpha.-D-glucopyranosyl O-.alpha.-D-glucopyranosyl-(1.fwdarw.6)-.alpha.-D-glucopyranoside is a novel non-reducing saccharide which promotes the growth of bifid bacteria, has an anti-caries activity, and promotes the mineral absorption. Similarly as the non-reducing saccharide, .alpha.-isomaltosyl .alpha.-glucoside and .alpha.-isomaltotriosyl .alpha.-glucoside can be also used to prevent caries and promote the growth of bifid bacteria and the mineral absorption. These saccharides can be used alone or in combination in a variety of foods, cosmetics and pharmaceuticals.

    摘要翻译： 由α-α-D-吡喃葡萄糖基 - （1-> 6）-β-D-吡喃葡萄糖基O-α-D-吡喃葡萄糖基 - （1-> 6）-β-D-吡喃葡萄糖苷代表的α-异麦角糖型α-异麦芽糖苷是 促进双歧杆菌生长的新型非还原性糖类具有抗龋齿活性，促进矿物质吸收。 类似地，作为非还原性糖，α-异麦芽糖基α-葡萄糖苷和α-异麦芽糖基α-葡糖苷也可用于预防龋齿并促进双歧杆菌的生长和矿物质吸收。 这些糖类可以单独使用，也可以组合使用于各种食品，化妆品，药​​品等。

    Non-reducing saccharides, their preparation and use
    10.
    发明授权
    Non-reducing saccharides, their preparation and use 失效
    非还原糖，其制备和用途

    公开(公告)号：US5858992A

    公开(公告)日：1999-01-12

    申请号：US962880

    申请日：1997-11-04

    申请人： Tomoyuki Nishimoto ,  Hiroto Chaen ,  Toshiyuki Sugimoto ,  Toshio Miyake

    发明人： Tomoyuki Nishimoto ,  Hiroto Chaen ,  Toshiyuki Sugimoto ,  Toshio Miyake

    IPC分类号： C07H3/06 ,  C12P19/04 ,  A61K31/715 ,  A01N43/04 ,  C07H1/00

    CPC分类号： C07H3/06 ,  C12P19/04

    摘要： .alpha.-Isomaltosyl .alpha.-isomaltoside represented by O-.alpha.-D-glucopyranosyl -(1.fwdarw.6)-.alpha.-D-glucopyranosyl O-.alpha.-D-glucopyranosyl-(1.fwdarw.6) -.alpha.-D-glucopyranoside is a novel non-reducing saccharide which promotes the growth of bifid bacteria, has an anti-caries activity, and promotes the mineral absorption. Similarly as the non-reducing saccharide, .alpha.-isomaltosyl .alpha.-glucoside and .alpha.-isomaltotriosyl .alpha.-glucoside can be also used to prevent caries and promote the growth of bifid bacteria and the mineral absorption. These saccharides can be used alone or in combination in a variety of foods, cosmetics and pharmaceuticals.

    摘要翻译： 由α-D-吡喃葡萄糖基 - （1-> 6）-β-D-吡喃葡萄糖基-O-α-D-吡喃葡萄糖基 - （1-> 6）-β-D-吡喃葡萄糖苷代表的α-甲氧咪唑烷基α-异麦芽糖苷是 促进双歧杆菌生长的新型非还原性糖类具有抗龋齿活性，促进矿物质吸收。 类似地，作为非还原性糖，α-异麦芽糖基α-葡萄糖苷和α-异麦芽糖基α-葡糖苷也可用于预防龋齿并促进双歧杆菌的生长和矿物质吸收。 这些糖类可以单独使用，也可以组合使用于各种食品，化妆品，药​​品等。