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11.发明授权公开(公告)号：US10822582B2
公开(公告)日：2020-11-03
申请号：US16046426
申请日：2018-07-26
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Nephi D. Jones , Christopher D. Brau
Abstract: A method for filtering a gas includes delivering a gas into a compartment of a gas filter assembly; applying a partial vacuum to the gas filter assembly so that the partial vacuum assists in drawing the gas through a porous filter body of the gas filter assembly that is at least partially disposed within the compartment of the gas filter assembly; and regulating the application of the partial vacuum based on a pressure reading of the gas upstream of the gas filter assembly.
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公开(公告)号：US10435658B2
公开(公告)日：2019-10-08
申请号：US13659616
申请日：2012-10-24
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones
IPC: B01F13/00 , B01F15/00 , C12N1/00 , C12N5/07 , C12Q3/00 , C12M3/02 , C12M1/00 , B01F7/00 , C12M3/00 , C12M1/06 , B01F7/02 , B01F15/02
Abstract: A fluid mixing system includes a support housing having an interior surface bounding a chamber. A flexible bag is disposed within the chamber of the support housing, the flexible bag having an interior surface bounding a compartment. An impeller is disposed within the chamber of the flexible bag. A drive shaft is coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller. A drive motor assembly is coupled with the draft shaft and is adapted to rotate the drive shaft. An adjustable arm assembly is coupled with the drive motor assembly and is adapted to move the drive motor assembly which in turn moves the position of the drive shaft and impeller. An electrical controller can control movement of the adjustable arm.
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公开(公告)号：US10350554B2
公开(公告)日：2019-07-16
申请号：US15473148
申请日：2017-03-29
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones , Derik R. West
Abstract: A container assembly includes a flexible bag having an interior surface bounding a chamber and an opposing exterior surface, the bag having a bottom end wall being comprised of a first sheet overlying a second sheet, the first sheet and the second sheet of the bottom end wall being welded together so as to form a first sparging area and a separated second sparging area that are both bounded between the first sheet and the second sheet, at least a portion of the first sheet overlying the first and second sparging areas being gas permeable.
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公开(公告)号：US20190125906A1
公开(公告)日：2019-05-02
申请号：US16233403
申请日：2018-12-27
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones , Bradley H. Buchanan
Abstract: A container includes a first wall and an opposing second wall that extend between a first end and an opposing second end, a first fluid flow path being bounded between the first wall and the second wall. An inlet is formed at the first end and communicates with the first fluid flow path. An outlet is formed at the second end and communicates with the first fluid flow path. The first wall includes a primary wall portion having a first opening extending therethrough in alignment with the first fluid flow path. A secondary wall portion extends over the first opening and is secured to the primary wall portion so as to seal the first opening closed, the secondary wall portion being comprised of a film having a thickness that is less than a thickness of the primary wall portion.
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公开(公告)号：US20170197185A1
公开(公告)日：2017-07-13
申请号：US15473148
申请日：2017-03-29
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones , Derik R. West
CPC classification number: B01F3/04269 , B01F15/0085 , B01F2003/04148 , B01F2003/04191 , B01F2003/04297 , B01F2003/04326 , B01F2003/04347 , B01F2003/04361 , B01F2215/0073 , C12M23/14 , C12M23/26 , C12M23/40 , C12M29/06
Abstract: A container assembly includes a flexible bag having an interior surface bounding a chamber and an opposing exterior surface, the bag having a bottom end wall being comprised of a first sheet overlying a second sheet, the first sheet and the second sheet of the bottom end wall being welded together so as to form a first sparging area and a separated second sparging area that are both bounded between the first sheet and the second sheet, at least a portion of the first sheet overlying the first and second sparging areas being gas permeable.
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Patent Agency Ranking
公开(公告)号：US20170088805A1
公开(公告)日：2017-03-30
申请号：US15374689
申请日：2016-12-09
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Clinton C. Staheli , Nephi D. Jones , Michael E. Goodwin
IPC: C12M1/00 , B01D5/00 , B01F3/04 , B01F7/16 , F28F3/12 , B01F7/00 , B01F15/00 , B01F15/06 , F28B1/02 , F28F21/06 , C12M1/02 , B01F7/22
Abstract: A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.
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公开(公告)号：US09388375B2
公开(公告)日：2016-07-12
申请号：US14395728
申请日：2013-03-15
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Christopher D. Brau , Nephi D. Jones , Benjamin R. Madsen , Michael E. Goodwin
IPC: C12M1/04 , C12M1/00 , B01F13/02 , B01F3/04 , C12M1/02 , C12M1/34 , B01F7/22 , B01F15/00 , B01F11/00
CPC classification number: C12M29/06 , B01F3/04439 , B01F3/0446 , B01F3/04531 , B01F7/22 , B01F11/0002 , B01F11/0082 , B01F13/0205 , B01F13/0211 , B01F13/0272 , B01F15/0085 , B01F2003/04879 , B01F2003/04943 , B01F2215/0073 , C12M23/00 , C12M23/14 , C12M23/26 , C12M27/00 , C12M27/02 , C12M29/14 , C12M41/34
Abstract: A method and system for achieving a gas-liquid mass transfer includes delivering into a compartment of a container a liquid, the liquid having an exposed top surface disposed within the compartment. A stream of a gas is passed over the top surface of the liquid so that the stream of gas produces turbulence on the top surface that is sufficient to achieve the gas-liquid mass transfer. In one embodiment the liquid is a culture that includes cells or microorganisms and the mass transfer functions to oxygenate the culture sufficient to sustain the cells or microorganisms.
Abstract translation: 用于实现气 - 液传质的方法和系统包括将液体输送到容器的隔室中，液体具有设置在隔室内的暴露的顶表面。 气体流通过液体的顶表面，使得气流在顶表面上产生足以实现气 - 液传质的湍流。 在一个实施方案中，液体是包含细胞或微生物的培养物，并且传质功能使培养物充氧足以维持细胞或微生物。
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公开(公告)号：US20150118753A1
公开(公告)日：2015-04-30
申请号：US14395728
申请日：2013-03-15
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Christopher D. Brau , Nephi D. Jones , Benjamin R. Madsen , Michael E. Goodwin
CPC classification number: C12M29/06 , B01F3/04439 , B01F3/0446 , B01F3/04531 , B01F7/22 , B01F11/0002 , B01F11/0082 , B01F13/0205 , B01F13/0211 , B01F13/0272 , B01F15/0085 , B01F2003/04879 , B01F2003/04943 , B01F2215/0073 , C12M23/00 , C12M23/14 , C12M23/26 , C12M27/00 , C12M27/02 , C12M29/14 , C12M41/34
Abstract: A method and system for achieving a gas-liquid mass transfer includes delivering into a compartment of a container a liquid, the liquid having an exposed top surface disposed within the compartment. A stream of a gas is passed over the top surface of the liquid so that the stream of gas produces turbulence on the top surface that is sufficient to achieve the gas-liquid mass transfer. In one embodiment the liquid is a culture that includes cells or microorganisms and the mass transfer functions to oxygenate the culture sufficient to sustain the cells or microorganisms.
Abstract translation: 用于实现气 - 液传质的方法和系统包括将液体输送到容器的隔室中，液体具有设置在隔室内的暴露的顶表面。 气体流通过液体的顶表面，使得气流在顶表面上产生足以实现气 - 液传质的湍流。 在一个实施方案中，液体是包含细胞或微生物的培养物，并且传质功能使培养物充氧足以维持细胞或微生物。
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公开(公告)号：US12128367B2
公开(公告)日：2024-10-29
申请号：US16953066
申请日：2020-11-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael E. Goodwin , Nephi D. Jones , Derik R. West
IPC: B01F23/23 , B01F23/231 , B01F35/513 , C12M1/00 , B01F101/44
CPC classification number: B01F23/23124 , B01F23/231241 , B01F35/513 , C12M23/14 , C12M23/26 , C12M23/40 , C12M29/06 , B01F23/23113 , B01F23/231151 , B01F23/231262 , B01F23/231266 , B01F23/231269 , B01F2101/44
Abstract: A container assembly includes a flexible bag having an interior surface bounding a chamber and an opposing exterior surface. The bag has a bottom end wall that includes a first sparger and a second sparger. The first sparger and the second sparger each have a flexible first sheet overlying a flexible second sheet, the first sheet and the second sheet being secured together so as to form a sparging area bounded between the first sheet and the second sheet, at least a portion of the first sheet overlying the sparging area being gas permeable so that gas can pass from the sparging area, through the first sheet, and into the chamber.
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公开(公告)号：US20240350992A1
公开(公告)日：2024-10-24
申请号：US18652521
申请日：2024-05-01
Applicant: Life Technologies Corporation
Inventor： Nephi D. Jones , Brandon M. Knudsen , Whitt F. Woods
IPC: B01F35/513 , B01F27/07 , B01F27/213 , B01F27/807 , B01F27/88 , B01F27/91 , B01F31/20 , B01F31/23 , B01F35/42 , B01F35/43 , B01F35/71 , B01F35/75 , C12M1/00 , C12M1/02 , C12M1/06 , C12M3/00 , C12M3/06
CPC classification number: B01F35/513 , B01F27/071 , B01F27/213 , B01F27/807 , B01F27/88 , B01F27/91 , B01F31/201 , B01F31/23 , B01F35/42 , B01F35/421 , B01F35/43 , B01F35/712 , B01F35/7548 , C12M23/14 , C12M23/48 , C12M23/52 , C12M27/00 , C12M27/02 , C12M27/16 , C12M29/06 , B01F35/715
Abstract: A method for mixing a fluid includes: dispensing a first volume of a fluid into a flexible container, the flexible container being at least partially disposed within the chamber of a support housing; repeatedly moving the support housing and the flexible container contained therein so as to mix the first volume of fluid within the flexible container; adding further fluid into the flexible container after moving the support housing to form a second volume of fluid; and manipulating a mixing element within the flexible container so as to mix the second volume of fluid.
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