E2F activity-inhibiting compound
    13.
    发明申请
    E2F activity-inhibiting compound 审中-公开
    E2F活性抑制化合物

    公开(公告)号:US20050137138A1

    公开(公告)日:2005-06-23

    申请号:US10752505

    申请日:2004-01-08

    CPC分类号: C07K14/4705 A61K38/00

    摘要: E2F-inhibiting compounds are represented by the general formula: R1-A-R2 wherein A represents a peptide sequence comprising a partial amino acid sequence having at least 12 continuous residues in the sequence of the dimerization region or DNA binding region of the E2F family), which are useful as a therapeutic agent of diseases such as tumor and arteriosclerosis, for which abnormal cellular growth is responsible.

    摘要翻译: E2F抑制化合物由以下通式表示:其中A表示包含部分氨基酸序列的肽序列,所述部分氨基酸序列具有至少12个连续残基 E2F家族的二聚化区域或DNA结合区域的序列),其可用作肿瘤和动脉硬化疾病的治疗剂,异常细胞生长负责。

    Method of manufacturing a piezoelectric vibrator capable of reliably
preventing dielectric breakdown
    16.
    发明授权
    Method of manufacturing a piezoelectric vibrator capable of reliably preventing dielectric breakdown 失效
    制造能够可靠地防止绝缘击穿的压电振动器的制造方法

    公开(公告)号:US5400488A

    公开(公告)日:1995-03-28

    申请号:US156280

    申请日:1993-11-22

    摘要: On a first piezoelectric sheet of a piezoelectric vibrator, a second piezoelectric sheet is stacked with interposition, between the sheets, of first-set electrodes, formed on an upper surface of the first piezoelectric sheet. Second-set electrodes are formed on an upper surface of the second piezoelectric sheet with each placed halfway between two adjacent ones of the first-set electrodes. The second piezoelectric sheet is poled in directions from each second-set electrode to the two adjacent ones of the first-set electrodes. Preferably, third-set electrodes are formed on a lower surface of the first piezoelectric sheet with each arranged halfway between two adjacent ones of the first-set electrodes. In this event, the first piezoelectric sheet is poled in directions from each third-set electrode to two adjacent ones of the first-set electrodes. Each first-set electrode has a first end along a side surface of the first piezoelectric sheet with each second-set and each third-set electrode possessed of a second and a third end along opposite side surfaces of the first and the second piezoelectric sheets. First and second common outside electrodes are formed on such side surfaces in contact with the first end of each first-set electrode either directly or through a first common electrode and in contact with the second and the third ends of the second-set and the third-set electrodes either directly or through second and third common electrodes.

    摘要翻译: 在压电振动器的第一压电片上,在第一压电片的上表面上形成第二压电片层叠在片之间的第一组电极之间。 第二组电极形成在第二压电片的上表面上,每个电极位于两个相邻的第一组电极之间的中间。 第二压电片从每个第二组电极到两个相邻的第一组电极的方向极化。 优选地,第三组电极形成在第一压电片的下表面上,每个电极布置在两个相邻的第一组电极之间的中间。 在这种情况下,第一压电片从每个第三组电极到两个相邻的第一组电极的方向极化。 每个第一组电极具有沿着第一压电片的侧表面的第一端,每个第二组电极和每个第三组电极具有沿着第一和第二压电片的相对侧表面的第二和第三端。 第一和第二公共外部电极形成在与第一组电极的第一端直接或通过第一公共电极接触并与第二组和第三组的第二和第三端接触的侧表面上 直接或通过第二和第三公共电极设置电极。

    Piezoelectric vibrator capable of reliably preventing dielectric
breakdown and a method of manufacturing the same
    17.
    发明授权
    Piezoelectric vibrator capable of reliably preventing dielectric breakdown and a method of manufacturing the same 失效
    能够可靠地防止绝缘击穿的压电振动器及其制造方法

    公开(公告)号:US5315205A

    公开(公告)日:1994-05-24

    申请号:US946946

    申请日:1992-09-17

    摘要: On a first piezoelectric sheet of a piezoelectric vibrator, a second piezoelectric sheet is stacked with interposition, between the sheets, of first-set electrodes (24(1), 24(2)) formed on an upper surface of the first piezoelectric sheet. Second-set electrodes are formed on an upper surface of the second piezoelectric sheet with each placed halfway between two adjacent ones of the first-set electrodes. The second piezoelectric sheet is poled in directions from each second-set electrode to the two adjacent ones of the first-set electrodes. Preferably, third-set electrodes are formed on a lower surface of the first piezoelectric sheet with each arranged halfway between two adjacent ones of the first-set electrodes. In this event, the first piezoelectric sheet is poled in directions from each third-set electrode to two adjacent ones of the first-set electrodes. Each first-set electrode has a first end along a side surface of the first piezoelectric sheet with each second-set and each third-set electrode possessed of a second and a third end along opposite side surfaces of the first and the second piezoelectric sheets. First and second common outside electrodes are formed on such side surfaces in contact with the first end of each first-set electrode either directly or through a first common electrode and in contact with the second and the third ends of the second-set and the third-set electrodes either directly or through second and third common electrodes.

    摘要翻译: 在压电振动器的第一压电片上,在第一压电片的上表面上形成的第一组电极(24(1),24(2))之间,在片之间叠置第二压电片。 第二组电极形成在第二压电片的上表面上,每个电极位于两个相邻的第一组电极之间的中间。 第二压电片从每个第二组电极到两个相邻的第一组电极的方向极化。 优选地,第三组电极形成在第一压电片的下表面上,每个电极布置在两个相邻的第一组电极之间的中间。 在这种情况下,第一压电片从每个第三组电极到两个相邻的第一组电极的方向极化。 每个第一组电极具有沿着第一压电片的侧表面的第一端,每个第二组电极和每个第三组电极具有沿着第一和第二压电片的相对侧表面的第二和第三端。 第一和第二公共外部电极形成在与第一组电极的第一端直接或通过第一公共电极接触并与第二组和第三组的第二和第三端接触的侧表面上 直接或通过第二和第三公共电极设置电极。

    Negative type silver halide photographic material and method for forming
image using the same
    18.
    发明授权
    Negative type silver halide photographic material and method for forming image using the same 失效
    负型卤化银照相材料及其形成方法

    公开(公告)号:US5051336A

    公开(公告)日:1991-09-24

    申请号:US522400

    申请日:1990-05-11

    CPC分类号: G03C1/09 G03C1/061

    摘要: A negative type silver halide photographic material is disclosed. The material comprises a support having provided thereon at least one silver halide emulsion layer containing silver halide grains sensitized with gold and sulfur sensitizers, the emulsion layer or at least one other hydrophilic colloid layer containing at least one high contrast-imparting hydrazine derivative and at least one compound represented by the following general formula (I): ##STR1## wherein Z represents N or C--X wherein X represents a substituted or unsubstituted alkyl or aryl group, Y represents a substituted or unsubstituted alkyl or aryl group, and M represents a hydrogen atom, a metallic atom, or ammonium which may be substituted.

    摘要翻译: 公开了负型卤化银照相材料。 该材料包括其上提供有至少一个含有由金和硫敏化剂敏化的卤化银颗粒的卤化银乳剂层的载体,所述乳剂层或至少一种其它亲水胶体层含有至少一种高对比度赋予肼衍生物,并且至少 一种由以下通式(I)表示的化合物:其中Z表示N或CX,其中X表示取代或未取代的烷基或芳基,Y表示取代或未取代的烷基或芳基,M表示 氢原子,金属原子或可被取代的铵。

    Method of forming image providing a change in sensitivity by altering
the pH of the developer

    公开(公告)号:US4873173A

    公开(公告)日:1989-10-10

    申请号:US110981

    申请日:1987-10-21

    IPC分类号: G03C5/29 G03C1/06 G03C5/30

    CPC分类号: G03C1/061 G03C5/30

    摘要: A method of forming an image is provided. The method comprises the steps of (a) imagewise exposing a photographic material which comprises a support having provided thereon at least one light-sensitive silver halide emulsion layer and which contains a hydrazine compound represented by the following general formula (I) in the emulsion layer or a hydrophilic colloid layer adjacent thereto, the photographic material being designed so that a difference in sensitivity (sensitivity being defined as log E corresponding to the density of fog+2.0) between (1) the photographic material is development-processed with a developing solution having a sulfite ion concentration of 0.15 mole/l or more, a potassium ion concentration of 0.2 mole/l or more and a pH value ranging from 10.5 to 12.3 and (2) the photographic material is development-processed with the same developing solution as described above, except that the pH value was lowered by 1.0, (.DELTA.log E), is 0.7 or less, and moreover, the gamma value obtained in (1) is 10 or more and the gamma value obtained in (2) is 5 or more: ##STR1## wherein A represents an aliphatic group, or an aromatic group; B represents a formyl group, an acyl group, an alkylsulfonyl group, an arylsulfonyl group, an alkylsulfinyl group, an arylsulfinyl group, a carbamoyl group, an alkoxycarbonyl group, an aryloxcarbonyl group, a sulfinamoyl group, an alkoxysulfonyl group, a thioacyl group, a thiocarbamoyl group, a sulfamoyl group, or a heterocyclic group; both R.sub.0 and R.sub.1 represent a hydrogen atom, or one of them represents a hydrogen atom and the other represents an alkysulfonyl group, an arylsulfonyl group, or an acyl group; and B, R.sub.1 and the nitrogen atom attached thereto may form a partial structure of hydrazone, and (b) developing the exposed material with a developer. The method realizes superhigh contrast and high resolution images.