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公开(公告)号：US20120139734A1
公开(公告)日：2012-06-07
申请号：US13322984
申请日：2009-05-29
申请人： Bo Olde , Eddie Nilsson , Derek White , Thierry Court , Eric Roussi
发明人： Bo Olde , Eddie Nilsson , Derek White , Thierry Court , Eric Roussi
CPC分类号： A61B5/0416 , A61B2562/227 , H01R11/22 , H01R2201/12
摘要： A connector clip for medical sensors, including a first main body having two main tip contacts in electrical contact with electrical wires connectable to an instrument and a second main body mounted on the first main body and movable with respect to the first main body between an open position and a closed position. Two auxiliary tip contacts and an electric/electronic circuit provided with two connecting leads each electrically connected to one of the two auxiliary tip contacts are positioned in first or second main body. When a disposable sensor tab is correctly located and clamped each of two contacts is in contact with one of the main tip contacts and one of the auxiliary tip contacts and the electric circuit is connected in parallel with an electrical circuit defined by the sensor
摘要翻译： 一种用于医疗传感器的连接器夹，包括第一主体，其具有与可连接到仪器的电线电接触的两个主尖端触点和安装在第一主体上的第二主体，并且可相对于第一主体在打开状态 位置和关闭位置。 两个辅助尖端触点和设置有两个连接引线的电气/电子电路，每个连接引线各自电连接到两个辅助尖端触点中的一个，其位于第一或第二主体中。 当一次性传感器突片正确定位并夹紧时，两个触点中的每一个与主尖端触点中的一个接触，并且辅助尖端触点之一和电路与由传感器限定的电路并联连接
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12.发明申请公开(公告)号：US20110106466A1
公开(公告)日：2011-05-05
申请号：US13001314
申请日：2009-06-26
申请人： Martin Furmanski , Anders Roslund , Bo Olde , Kristian Solem , Thomas Hertz , Jan Sternby
发明人： Martin Furmanski , Anders Roslund , Bo Olde , Kristian Solem , Thomas Hertz , Jan Sternby
CPC分类号： G01M3/2846 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , G01L27/002 , G01M3/2815 , G01N33/49
摘要： A surveillance device monitors the integrity of a fluid connection between first and second fluid containing systems based on at least one time-dependent measurement signal from a pressure sensor in the first fluid containing system. The first fluid containing system comprises a first pulse generator, and the second fluid containing system comprises a second pulse generator. The pressure sensor is arranged to detect first pulses originating from the first pulse generator and second pulses originating from the second pulse generator. The integrity of the fluid connection is determined based on the presence of second pulses in the measurement signal. The second pulses may be detected by analysing the measurement signal in the time domain and/or by using timing information indicative of the timing of the second pulses in said at least one measurement signal. The analysis may be based on a parameter value that represents a distribution of signal values within a time window of the measurement signal. The parameter value may be calculated as a statistical dispersion measure of the signal values, or may result from a matching of the signal values within the time window to a predicted temporal signal profile of a second pulse. The fluid connection may be established between a human blood system and an extracorporeal blood flow circuit.
摘要翻译： 监视装置基于来自第一流体容纳系统中的压力传感器的至少一个与时间相关的测量信号监测第一和第二流体容纳系统之间的流体连接的完整性。 第一流体容纳系统包括第一脉冲发生器，并且第二流体容纳系统包括第二脉冲发生器。 压力传感器被布置成检测源自第一脉冲发生器的第一脉冲和来自第二脉冲发生器的第二脉冲。 基于测量信号中第二个脉冲的存在来确定流体连接的完整性。 可以通过在时域中分析测量信号和/或通过使用指示所述至少一个测量信号中的第二脉冲的定时的定时信息来检测第二脉冲。 分析可以基于表示测量信号的时间窗内的信号值分布的参数值。 参数值可以被计算为信号值的统计色散测量值，或者可以由时间窗口内的信号值与第二脉冲的预测时间信号曲线的匹配产生。 可以在人体血液系统和体外血液回路之间建立流体连接。
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公开(公告)号：US11123010B2
公开(公告)日：2021-09-21
申请号：US13519067
申请日：2010-12-22
申请人： Bo Olde , Kristian Solem
发明人： Bo Olde , Kristian Solem
摘要： A monitoring arrangement 100 is configured to predict a rapid symptomatic drop in a subject's blood pressure, e.g. during a medical treatment or when operating aircraft. To this aim, a pulse shape parameter (pps) with respect to a peripheral body part (105) of the subject (P) is repeatedly registered by means of a pulse oximetry instrument (110) adapted to detect light response variations in blood vessels. A respective pulse magnitude measure is calculated based on each of a number of received pulse shape parameters (pps), and a statistical dispersion measure is calculated based on the thus-calculated pulse magnitude measure. It is investigated whether or not the statistical dispersion measure fulfils a decision criterion relative to a reference measure. An output signal (α) is generated if the decision criterion is found to be fulfilled.
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公开(公告)号：US10980431B2
公开(公告)日：2021-04-20
申请号：US13519559
申请日：2010-12-22
申请人： Bo Olde , Kristian Solem
发明人： Bo Olde , Kristian Solem
IPC分类号： A61B5/0215 , A61M1/36
摘要： A monitoring device is included in a medical system to implement a method for prediction of a rapid symptomatic drop in a subject's blood pressure, e.g. during a medical treatment such as dialysis. To this aim, a pulse shape parameter (pPS) with respect to a pulse generator of the subject is registered by means of a pressure sensor arranged in an extracorporeal blood flow circuit coupled to a cardiovascular system of the subject (P). The pressure sensor is configured to detect pressure variations in blood vessels of the subject (P). It is investigated, during measurement period, whether or not one or more of the pulse shape parameters fulfil a decision criterion. An output signal (a) is generated if the decision criterion is found to be fulfilled, to indicate a predicted rapid symptomatic blood pressure decrease in the subject (P). The decision criterion may operate on pulse magnitude measures calculated for the received pulse shape parameters (pPS), or statistical dispersion measures calculated based on the thus-calculated pulse magnitude measures.
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公开(公告)号：US09612182B2
公开(公告)日：2017-04-04
申请号：US13519248
申请日：2010-12-22
申请人： Bo Olde , Kristian Solem
发明人： Bo Olde , Kristian Solem
CPC分类号： G01N11/02 , A61M1/3639 , A61M1/3653 , A61M1/3656 , A61M1/3661 , A61M5/16859 , A61M2205/13 , A61M2205/15 , A61M2205/3331 , A61M2230/04
摘要： A device and method for detecting fault conditions in a fluid connection system between a first fluid containing system including a first pulse generator (e.g., an extracorporeal blood circuit) and a second fluid containing system including a second pulse generator (e.g., a human or animal vascular system). A pressure sensor detects first pulses from the first pulse generator and second pulses from the second pulse generator. A time-dependent monitoring signal based on data obtained from said pressure sensor is generated and processed to calculate a parameter value indicative of the shape of at least part of a first pulse in the monitoring signal. The parameter value is evaluated to detect the fault condition. The fault condition may involve disconnection of an access device; reversed connection of access devices; occlusion of the fluid path through an access device; or infiltration in tissue surrounding an access point in the vascular system.
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公开(公告)号：US20130172803A1
公开(公告)日：2013-07-04
申请号：US13519148
申请日：2010-12-22
申请人： Bo Olde , Kristian Solem , Thomas Hertz , Jan Sternby , Anders Wieslander
发明人： Bo Olde , Kristian Solem , Thomas Hertz , Jan Sternby , Anders Wieslander
IPC分类号： A61M1/30
CPC分类号： A61M1/3656 , A61B5/02125 , A61B5/0215 , A61B5/02405 , A61B5/4836 , A61M1/30 , A61M1/3643 , A61M1/3644 , A61M1/3653 , A61M1/3659 , A61M2205/3331 , A61M2205/6018
摘要： A control system (23) is arranged to control the operation of an apparatus (200) for extracorporeal blood treatment. The apparatus (200) comprises an extracorporeal blood circuit (20) and a connection system (C) for connecting the blood circuit (20) to the vascular system of a patient. The blood circuit (20) comprises a blood processing device (6), and at least one pumping device (3). The control system is operable to switch between a pre-treatment mode and a blood treatment mode. The blood treatment mode involves operating the blood circuit (20) to pump blood from the vascular system via the connection system (C) through the blood processing device (6) and back to the vascular system via the connection system (C). The control system (23) is operable to obtain measurement data from at least one energy transfer sensor (40) arranged to sense a transfer of energy between the patient and the connection system (C) or between the patient and the blood circuit (20). The control system (23) is configured to, in the pre-treatment mode, process the measurement data for identification of a characteristic change indicating a connection of the blood circuit (20) to the vascular system of the patient, and, upon such identification, take dedicated action. The action may involve activating at least part of a patient protection system and/or enabling entry into the blood treatment mode. The control system may be included in an apparatus (200) for blood treatment, such as a dialysis machine.
摘要翻译： 控制系统（23）被布置成控制用于体外血液处理的装置（200）的操作。 装置（200）包括用于将血液回路（20）连接到患者血管系统的体外血液回路（20）和连接系统（C）。 血液回路（20）包括血液处理装置（6）和至少一个泵送装置（3）。 控制系统可操作以在预处理模式和血液处理模式之间切换。 血液处理模式包括操作血液回路（20），以经由连接系统（C）从血管系统通过血液处理装置（6）泵送血液，并通过连接系统（C）返回血管系统。 控制系统（23）可操作以从至少一个能量传递传感器（40）获得测量数据，所述能量传递传感器（40）布置成感测患者和连接系统（C）之间或患者与血液回路（20）之间的能量传递， 。 控制系统（23）被配置为在预处理模式下处理用于识别指示血液回路（20）与患者的血管系统的连接的特征变化的测量数据，并且在这种识别 ，采取专门的行动。 该动作可以涉及激活患者保护系统的至少一部分和/或使得能够进入血液处理模式。 控制系统可以包括在用于血液处理的装置（200）中，例如透析机。
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公开(公告)号：US20120283581A1
公开(公告)日：2012-11-08
申请号：US13380631
申请日：2010-06-24
申请人： Bo Olde , Kristian Solem
发明人： Bo Olde , Kristian Solem
IPC分类号： A61B5/021
CPC分类号： A61B5/02 , A61B5/021 , A61B5/02125 , A61B5/0816 , A61B5/0823 , A61B5/4094 , A61B5/411 , A61B5/4818 , A61M1/3639 , A61M2205/3331 , A61M2205/50 , A61M2230/06 , A61M2230/40 , A61M2230/63
摘要： A monitoring device receives a measurement signal obtained by a pressure sensor in an extracorporeal fluid system, such as an extracorporeal blood circuit for a dialysis machine which is in contact with a vascular system of a subject via a fluid connection. The monitoring device processes the measurement signal to identify pressure data that represents pulses originating from a first physiological phenomenon in the subject, excluding the heart of the subject. The first physiological phenomenon may be any of reflexes, voluntary muscle contractions, non-voluntary muscle contractions, a breathing system of the subject, an autonomous system of the subject for blood pressure regulation, or an autonomous system of the subject for body temperature regulation. The monitoring device may detect, present, track or predict a disordered condition of the subject using the pressure data, or monitor the integrity of the fluid connection based on the pressure data.
摘要翻译： 监测装置接收由体液流体系统中的压力传感器获得的测量信号，所述体外流体系统例如经由流体连接与受试者的血管系统接触的用于透析机的体外血液回路。 监测装置处理测量信号以识别表示来自对象中的第一生理现象的脉冲的压力数据，不包括对象的心脏。 第一种生理现象可以是任何反射，自愿肌肉收缩，非自愿肌肉收缩，受试者的呼吸系统，血压调节受试者的自主系统或体温调节对象的自主系统。 监视装置可以使用压力数据来检测，呈现，跟踪或预测对象的无序状态，或者基于压力数据监视流体连接的完整性。
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公开(公告)号：US20110040502A1
公开(公告)日：2011-02-17
申请号：US12988146
申请日：2009-04-16
申请人： Martin Furmanski , Andres Roslund , Bo Olde , Kristian Solem
发明人： Martin Furmanski , Andres Roslund , Bo Olde , Kristian Solem
CPC分类号： G01M3/2815 , A61M1/3639 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M5/16859 , A61M2205/15 , A61M2205/18 , A61M2230/06
摘要： A device is provided for monitoring the integrity of a flow circuit in fluid communication with a receptacle. The flow circuit comprises a pumping device for transferring fluid through the flow circuit. The device operates according to a monitoring method in which a pressure signal is received from a pressure sensor, the pressure signal being indicative of fluid pressure in the receptacle or the flow circuit. The pressure signal is then processed for detection of a beating signal. The beating signal manifests itself as an amplitude modulation of the pressure signal and is formed by interference between pressure waves generated by a pulse generator associated with the receptacle and pressure waves generated by the pumping device. The integrity of the flow circuit is determined based at least partly on the presence or absence of the beating signal. The device and the flow circuit may be part of an apparatus for extracorporeal blood treatment, and the method may be implemented as a computer program product.
摘要翻译： 提供了一种用于监测与容器流体连通的流动回路的完整性的装置。 流动回路包括用于通过流动回路传送流体的泵送装置。 该装置根据其中从压力传感器接收压力信号的监测方法进行操作，压力信号表示容器或流路中的流体压力。 然后处理压力信号以检测跳动信号。 跳动信号表现为压力信号的幅度调制，并且由与由插座相关联的脉冲发生器产生的压力波和由泵送装置产生的压力波之间的干扰形成。 至少部分地基于跳动信号的存在或不存在确定流动电路的完整性。 装置和流路可以是用于体外血液处理的装置的一部分，并且该方法可以被实现为计算机程序产品。
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公开(公告)号：US09427513B2
公开(公告)日：2016-08-30
申请号：US14129087
申请日：2012-05-23
申请人： Mattias Holmer , Bo Olde , Kristian Solem
发明人： Mattias Holmer , Bo Olde , Kristian Solem
CPC分类号： A61M1/367 , A61M1/3639 , A61M1/3653 , A61M1/3655 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , A61M2205/3331 , A61M2205/3351 , G01N19/00
摘要： A device monitors a blood path from a blood vessel access of a human subject through an extracorporeal blood processing apparatus and back to the blood vessel access. A pumping device in the blood path is operable to pump blood through the blood path from the blood withdrawal device to the blood return device. The monitoring device obtains pressure data from a pressure sensor arranged upstream of the pumping device in the blood path, and processes the pressure data for detection of a disruption of the blood path downstream of the pumping device, e.g. caused by VND (Venous Needle Dislodgement). The disruption is detected by evaluating presence/absence of cross-talk pulses at the pressure sensor, where the cross-talk pulses originate from one or more pulse generators in the extracorporeal blood processing apparatus and have propagated on a propagation path in a direction downstream of the pumping device through the blood return device, the blood vessel access and the blood withdrawal device to the pressure sensor.
摘要翻译： 一种装置通过体外血液处理装置监测来自人体受试者的血管通路的血液通路并返回到血管通路。 血液路径中的抽吸装置可操作以将血液通过血液通道从血液提取装置泵送到血液返回装置。 监测装置从布置在血液路径中的泵送装置上游的压力传感器获取压力数据，并处理用于检测泵送装置下游的血液路径破裂的压力数据，例如， 由VND引起的（静脉针脱落）。 通过评估压力传感器处的串扰脉冲的存在/不存在来检测中断，其中串扰脉冲源自体外血液处理设备中的一个或多个脉冲发生器，并且在传播路径上沿着下游的方向传播 泵送装置通过血液回流装置，血管通路和取血装置到压力传感器。
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公开(公告)号：US08981948B2
公开(公告)日：2015-03-17
申请号：US13322984
申请日：2009-05-29
申请人： Bo Olde , Eddie Nilsson , Derek White , Thierry Court , Eric Roussi
发明人： Bo Olde , Eddie Nilsson , Derek White , Thierry Court , Eric Roussi
CPC分类号： A61B5/0416 , A61B2562/227 , H01R11/22 , H01R2201/12
摘要： A connector clip for medical sensors, including a first main body having two main tip contacts in electrical contact with electrical wires connectable to an instrument and a second main body mounted on the first main body and movable with respect to the first main body between an open position and a closed position. Two auxiliary tip contacts and an electric/electronic circuit provided with two connecting leads each electrically connected to one of the two auxiliary tip contacts are positioned in first or second main body. When a disposable sensor tab is correctly located and clamped each of two contacts is in contact with one of the main tip contacts and one of the auxiliary tip contacts and the electric circuit is connected in parallel with an electrical circuit defined by the sensor.
摘要翻译： 一种用于医疗传感器的连接器夹，包括第一主体，其具有与可连接到仪器的电线电接触的两个主尖端触点和安装在第一主体上的第二主体，并且可相对于第一主体在打开状态 位置和关闭位置。 两个辅助尖端触点和设置有两个连接引线的电气/电子电路，每个连接引线各自电连接到两个辅助尖端触点中的一个，其位于第一或第二主体中。 当一次性传感器突片正确定位并夹紧时，两个触点中的每一个与主尖端触点中的一个接触，并且一个辅助尖端触点和电路与由传感器限定的电路并联连接。
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