公开(公告)号：US12128129B2

公开(公告)日：2024-10-29

申请号：US17254347

申请日：2019-06-26

Applicant: SYMRISE AG ,  PROBI AB

Inventor： Manuel Pesaro ,  Dominik Stuhlmann ,  Lisa Garbe ,  Gerhard Schmaus ,  Kerstin Holmgren ,  Niklas Larsson

IPC: A61K8/99 ,  A61G19/00 ,  A61K8/02 ,  A61K9/14 ,  A61K35/747 ,  A61P17/00 ,  A61P29/00 ,  A61Q19/00

CPC classification number: A61K8/99 ,  A61G19/00 ,  A61K8/0225 ,  A61K9/14 ,  A61K35/747 ,  A61P17/00 ,  A61P29/00

Abstract: The present invention relates to microorganisms for use in the treatment and/or prevention of skin conditions by topical application. In particular, the microorganisms are for use in the treatment and/or prevention of loss of skin barrier function, inflammatory conditions and/or growth of pathogenic microorganism. The invention further relates to pharmaceutical or cosmetic compositions or products comprising the microorganisms Provided is also a cosmetic use of the microorganisms or compositions for application on the skin and a cosmetic method, in particular to improve the appearance of the skin.

公开(公告)号：US12076436B2

公开(公告)日：2024-09-03

申请号：US17737206

申请日：2022-05-05

Applicant: Symrise AG

Inventor： Andrew McShea ,  Katrina Nielsen ,  Joachim Hans ,  Mirjam Knupfer ,  Dominik Stuhlmann ,  Imke Meyer ,  Léa Schmidt ,  Marco Massironi ,  Francesca Benato ,  Sandro Rosa

IPC: A61K8/99 ,  A61K35/74 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q19/00 ,  A61Q19/08 ,  A61Q19/10 ,  C12N1/20

CPC classification number: A61K8/99 ,  A61K35/74 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q19/007 ,  A61Q19/08 ,  A61Q19/10 ,  C12N1/20

Abstract: A bacterial ferment obtained by a method including the following steps: (a) culturing Lactobacillus species in at least one growth medium for at least 24 hours; (b) separating the mixture via centrifugation; (c) adding lactic acid to the supernatant obtained from step b) in an amount sufficient to lower the pH value of the supernatant; (d) stabilizing the resulting mixture with the addition of at least one preservative and/or at least one multifunctional; and optionally (e) filtering the mixture to remove any final precipitation.

公开(公告)号：US11696884B2

公开(公告)日：2023-07-11

申请号：US15554791

申请日：2016-02-17

Applicant: Symrise AG

Inventor： Cécile Kalem ,  Dominik Stuhlmann ,  Aurélie Trunet ,  Denis Brouard

IPC: A61K8/49 ,  A61Q19/00 ,  A61K8/42 ,  A61K8/37 ,  A61K8/34 ,  A61Q5/10 ,  A61Q5/04 ,  A61Q5/08 ,  A61Q5/12

CPC classification number: A61K8/498 ,  A61K8/34 ,  A61K8/345 ,  A61K8/37 ,  A61K8/375 ,  A61K8/42 ,  A61K8/4973 ,  A61Q5/04 ,  A61Q5/08 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q19/005 ,  A61K2800/244

Abstract: The present invention relates to a soothing composition, comprising (a) menthol compounds, and (b) one or more cosmetically acceptable carriers.

公开(公告)号：US11622920B2

公开(公告)日：2023-04-11

申请号：US15778693

申请日：2015-12-03

Applicant: Symrise AG

Inventor： Gerhard Schmaus ,  Sabine Lange ,  Ann Christin Weseloh ,  Dominik Stuhlmann

IPC: A61K8/02 ,  A61Q19/00 ,  A61K8/06 ,  A61K8/60 ,  A61K8/64 ,  A61K8/73 ,  A61Q19/02 ,  A61Q19/06 ,  A61Q19/08 ,  A61K8/34 ,  A61K8/37 ,  A61Q19/04 ,  A61K8/9783 ,  A61K8/35 ,  A61K8/49 ,  A61K8/65

Abstract: The present invention belongs to the area of cosmetics, especially to a delivery system for actives to the skin, such as face masks and facial masks. Particularly, the present invention refers to a delivery system consisting of a basic body comprises nonwoven fibrous materials and an active-substance preparation which is an o/w emulsion or w/o emulsion, and a wetting liquid that comprises one or more actives to activate the delivery system.

公开(公告)号：US11219593B2

公开(公告)日：2022-01-11

申请号：US16608907

申请日：2017-04-28

Applicant: SYMRISE AG

Inventor： Martina Herrmann ,  Sandra Gaebler ,  Manuel Pesaro ,  Dominik Stuhlmann ,  Lisa Garbe ,  Julia Meyer

IPC: A61K36/28 ,  A61K8/9789 ,  A23L2/04 ,  A23L2/08 ,  A23L2/10 ,  A23L2/12 ,  A61K9/00 ,  A61K47/36 ,  A61Q5/00 ,  A61Q19/00

Abstract: The present invention relates to a yarrow fresh plant press juice concentrate and a gentle method for its manufacture. The yarrow fresh plant press juice concentrate is used in cosmetic compositions, pharmaceutical compositions, food compositions or food supplements. This invention also relates to new aspects of the use of yarrow. The invention provides the use of yarrow to stimulate the expression of heat shock proteins and/or antimicrobial peptides in skin cells. It also describes the use of yarrow to increase the thermal tolerance of the skin.

公开(公告)号：US11123272B2

公开(公告)日：2021-09-21

申请号：US16465228

申请日：2016-12-02

Applicant: Symrise AG

Inventor： Caroline Baptiste ,  Aurélie Trunet ,  Gabriele Vielhaber ,  Sabine Lange ,  Dominik Stuhlmann ,  Benoit Join ,  Oskar Koch

IPC: A61K8/34 ,  A61Q19/00 ,  A61Q19/10 ,  A61Q15/00 ,  A61Q5/02 ,  A61Q19/08 ,  A61Q17/04 ,  A61Q11/00

Abstract: Suggested is a cosmetic blend, comprising or consisting of (a) at least one TRPV1 and/or TRPV3 modulator and (b1) at least one 1,2-alkandiol having 5 to 12 carbon atoms and/or (b2) at least one polyol having 3 to 12 carbon atoms and 3 to 6 hydroxyl groups.

公开(公告)号：US20240075086A1

公开(公告)日：2024-03-07

申请号：US18244798

申请日：2023-09-11

Applicant: SYMRISE AG

Inventor： Martina Herrmann ,  Sandra Gaebler ,  Dominik Stuhlmann ,  Ann-Christin Weseloh

IPC: A61K36/05 ,  A61K8/9722 ,  A61K8/60 ,  A61K8/67 ,  A61K31/455 ,  A61K47/26 ,  A61K47/40

CPC classification number: A61K36/05 ,  A61K8/9722 ,  A61K8/60 ,  A61K8/675 ,  A61K31/455 ,  A61K47/26 ,  A61K47/40

Abstract: The present invention discloses a composition comprising sugar alcohols or a combination of sugar alcohols and a Tetraselmis extract or either of the former together with niacinamide for treating or preventing dysfunctions of the human hair or skin or as a skin or hair care product.

公开(公告)号：US20240000746A1

公开(公告)日：2024-01-04

申请号：US18253022

申请日：2021-11-17

Applicant: Symrise AG

Inventor： Judith Minakar ,  Benoit Join ,  Michael Backes ,  Saskia Hupe ,  Dominik Stuhlmann ,  Joachim Hans ,  Gabriela Matuszko

IPC: A61K31/357 ,  A61K31/341 ,  A61K31/4155 ,  A61K31/4436 ,  A61K31/443 ,  A61K31/444 ,  A61K8/41 ,  A61Q19/00 ,  A61Q11/00 ,  A61Q17/00 ,  A61Q5/00

CPC classification number: A61K31/357 ,  A61K31/341 ,  A61K31/4155 ,  A61K31/4436 ,  A61K31/443 ,  A61K31/444 ,  A61K8/41 ,  A61Q19/00 ,  A61Q11/00 ,  A61Q17/00 ,  A61Q5/00 ,  A61K2800/244

Abstract: The present invention relates to novel physiological cooling agents, cooling agent mixtures containing said novel agents, mixtures of said cooling agents with flavourings, the use of said cooling agents, and articles and final consumer preparations containing said physiological cooling agents or cooling agent mixtures.

公开(公告)号：US20230118467A1

公开(公告)日：2023-04-20

申请号：US17909693

申请日：2020-03-06

Applicant: SYMRISE AG

Inventor： Martina Herrmann ,  Gerhard Schmaus ,  Nikolas Bugdahn ,  Dominik Stuhlmann ,  Katharina Striewe ,  Holger Joppe

IPC: A61K8/42 ,  A61K8/9794 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q3/00 ,  A61Q5/00 ,  A61K31/164 ,  A61K36/899 ,  A23L33/105

Abstract: The present invention relates generally to: the cosmetic or pharmaceutical use of avenanthramide L or an oat extract comprising avenanthramide L; avenanthramide L or an oat extract comprising avenanthramide L as a neurokinin-1 receptor NK1R antagonist; and a method for preparing of preparing avenalumic acid and/or avenanthramide L.

公开(公告)号：US20220175859A1

公开(公告)日：2022-06-09

申请号：US16976023

申请日：2019-02-27

Applicant: SYMRISE AG

Inventor： Martina Herrmann ,  Sandra Gaebler ,  Dominik Stuhlmann ,  Ann-Christin Weseloh ,  Imke Meyer

IPC: A61K36/05 ,  A61K31/455 ,  A61K8/9722 ,  A61K45/06 ,  A61Q19/00 ,  A61Q5/00

Abstract: The present invention relates to a novel extract and a method for obtaining such an effective Tetraselmis extract which was found to have advantages in dermatological treatments and can be employed as a topical cosmetic.