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    PRODUCTION PROCESS OF GENDER-SPECIFIC SERUM AND BIOMARKER USING THE SERUM
    12.
    发明申请
    PRODUCTION PROCESS OF GENDER-SPECIFIC SERUM AND BIOMARKER USING THE SERUM 审中-公开
    使用血清的性别特异性血清和生物标记物的生产过程

    公开(公告)号：US20120028359A1

    公开(公告)日：2012-02-02

    申请号：US13263182

    申请日：2010-04-06

    申请人： In Ho Choi ,  Dong Mok Lee ,  Jong Soo Chang ,  Hyun Jeong Lee ,  Eun Ju Lee ,  Bajracharya Prati ,  Yu Mi Shin

    发明人： In Ho Choi ,  Dong Mok Lee ,  Jong Soo Chang ,  Hyun Jeong Lee ,  Eun Ju Lee ,  Bajracharya Prati ,  Yu Mi Shin

    IPC分类号： G01N33/12 ,  C07C57/03 ,  C07H21/02 ,  C07C53/00 ,  G01N33/92 ,  C07K16/18

    CPC分类号： G01N33/92 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  G01N33/743 ,  G01N2800/044

    摘要： The present invention relates to a production process of a gender-specific serum and a biomarker using the serum. More specifically, the present invention uses a fatty acid that exhibits a specific expression pattern in a gender-specific serum as a biomarker not only for diagnosis of obesity or a disease related to obesity, but also for diagnosis of meat quality since the fatty acid promotes differentiation of muscle derived stem cells into adipose cells. In addition, the present invention can establish a research system studying the effects of steroid hormones on the cell culture by using sera separated from blood that is collected from individual mammal carcasses being disposed, and provide important clues for discovering a gene associated with the synthesis of steroid hormone and for developing treatments for human diseases. Further, the present invention may contribute to increased profits derived from producing high quality sera, a reduced cost with treatment for carcass wastes, and promotion of the eco-industry for reducing environmental hormones.

    摘要翻译： 本发明涉及使用血清的性别特异性血清和生物标志物的制备方法。 更具体地，本发明使用在性别特异性血清中表现出特异性表达模式的脂肪酸作为生物标志物，不仅用于诊断肥胖症或与肥胖有关的疾病，而且还用于肉质量的诊断，因为脂肪酸促进 将肌肉干细胞分化为脂肪细胞。 此外，本发明可以建立研究系统，通过使用从被处置的各个哺乳动物尸体收集的血液分离的血清，研究类固醇激素对细胞培养物的作用，并提供发现与合成相关的基因的重要线索 类固醇激素和用于开发人类疾病的治疗。 此外，本发明可以有助于生产高质量血清的利润增加，屠体废物处理成本降低，促进生态工业减少环境激素。

    Method for manufacturing organic molecular device
    14.
    发明授权
    Method for manufacturing organic molecular device 有权
    有机分子装置的制造方法

    公开(公告)号：US07510663B2

    公开(公告)日：2009-03-31

    申请号：US10727900

    申请日：2003-12-05

    申请人： Seong Jin Kim ,  Hyoyoung Lee ,  Mun Seok Jeong ,  Tae Hyoung Zyung ,  Do Hyun Kim ,  Eun Ju Lee

    发明人： Seong Jin Kim ,  Hyoyoung Lee ,  Mun Seok Jeong ,  Tae Hyoung Zyung ,  Do Hyun Kim ,  Eun Ju Lee

    IPC分类号： C23F1/00

    CPC分类号： H01L51/0595 ,  B82Y10/00 ,  H01L51/0021 ,  H01L51/005 ,  H01L51/0579

    摘要： Disclosed is a method for manufacturing a conductive organic thin film device. An air-bridge type of an upper electrode is formed over a lower electrode by using a sacrificial layer and then a gap having a thickness of several nano meter is formed in a part at which the upper electrode and the lower electrode intersect by removing the sacrificial layer. The conductive organic molecules are uniformly adsorbed between the upper electrode and the lower electrode of the nano gap. Adsorption extent of the conductive organic molecules is confirmed by observing a current flowing through the upper and lower electrodes when the conductive organic molecules are adsorbed. Thus, reproducibility of a manufacturing process is improved and mass production is facilitated by adoption of a standardized process.

    摘要翻译： 公开了一种导电有机薄膜器件的制造方法。 通过使用牺牲层在下电极上形成上电极的气桥型，然后在上电极和下电极相交的部分中除去牺牲层，形成厚度为几纳米的间隙 层。 导电有机分子被均匀地吸附在纳米间隙的上电极和下电极之间。 当导电有机分子吸附时，通过观察流过上下电极的电流来确认导电有机分子的吸附程度。 因此，通过采用标准化方法，提高了制造工艺的再现性并促进了批量生产。

    Non-aqueous lithium secondary battery containing hydrophobic, inactive particle
    15.
    发明授权
    Non-aqueous lithium secondary battery containing hydrophobic, inactive particle 有权
    含有疏水性非活性粒子的非水锂二次电池

    公开(公告)号：US09419283B2

    公开(公告)日：2016-08-16

    申请号：US12310343

    申请日：2007-08-04

    申请人： Ji Heon Ryu ,  Jung Eun Hyun ,  Eun Ju Lee ,  Hanho Lee

    发明人： Ji Heon Ryu ,  Jung Eun Hyun ,  Eun Ju Lee ,  Hanho Lee

    IPC分类号： H01M4/62 ,  H01M4/02 ,  H01M4/13 ,  H01M10/052 ,  H01M10/42 ,  H01M4/131 ,  H01M4/133

    CPC分类号： H01M4/62 ,  H01M4/13 ,  H01M4/131 ,  H01M4/133 ,  H01M10/052 ,  H01M10/4235 ,  Y02E60/122 ,  Y02P70/54

    摘要： Provided is a non-aqueous lithium secondary battery comprising an electrode assembly composed of a cathode, an anode, and a separator interposed between the cathode and anode, wherein the cathode and anode have an electrode material containing an active material applied on a current collector, a non-aqueous electrolyte containing a lithium salt, hydrophobic inactive-particles (also, referred to as “hydrophobic particles”) included in the electrode material, and a battery case sealing all the constituent components. Upon adding hydrophobic inactive-particles to the electrode material in a non-aqueous lithium secondary battery, absorption and inflow of water into the electrode material during the battery production is effectively inhibited such as to prevent side reactions caused by water inside the battery, thereby exhibiting improvement in the high-temperature storage characteristics of the battery.

    摘要翻译： 提供一种非水锂二次电池，其包括由阴极，阳极和插入在阴极和阳极之间的隔膜组成的电极组件，其中阴极和阳极具有包含施加在集电体上的活性材料的电极材料， 含有锂盐的非水电解质，包含在电极材料中的疏水性非活性粒子（也称为“疏水性粒子”），以及密封所有构成成分的电池壳体。 在非水系锂二次电池中，在电极材料中添加疏水性非活性粒子时，能够有效地抑制电池制造时的电极材料的吸收和流入，防止电池内部的水引起的副反应， 改善电池的高温存储特性。

    Method of inducing high activity of human adipose stem cell and medium therefor
    17.
    发明授权
    Method of inducing high activity of human adipose stem cell and medium therefor 有权
    诱导人类脂肪干细胞及其培养基高活性的方法

    公开(公告)号：US08697441B2

    公开(公告)日：2014-04-15

    申请号：US13510528

    申请日：2010-10-08

    申请人： Hyo Soo Kim ,  Hyun Jae Kang ,  Eun Ju Lee

    发明人： Hyo Soo Kim ,  Hyun Jae Kang ,  Eun Ju Lee

    IPC分类号： C12N5/071

    CPC分类号： C12N5/0667 ,  C12N2500/36 ,  C12N2502/1305

    摘要： The present invention relates to a method of inducing high activity of human adipose stem cells, highly active stem cells induced by the method, cell therapeutic agents including the highly active stem cells, and a medium for inducing high activity of human adipose stem cells. The method of the present invention enables a long-term culture of human adipose stem cells while maintaining high activity, production yield and differentiation potency of the stem cells through in vitro culture, even in case culture conditions are not appropriate for mature human adipocytes, security of adipocytes is not guaranteed, or adipocytes are diseased.

    摘要翻译： 本发明涉及一种诱导人类脂肪干细胞高活性的方法，由该方法诱导的高活性干细胞，包括高活性干细胞的细胞治疗剂和诱导人类脂肪干细胞高活性的培养基。 本发明的方法能够通过体外培养保持人体脂肪干细胞的长期培养，同时通过体外培养保持干细胞的高活性，产量和分化效能，即使培养条件不适合成熟的人类脂肪细胞，安全性 的脂肪细胞不能保证，或脂肪细胞患病。