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公开(公告)号:US08273347B2
公开(公告)日:2012-09-25
申请号:US10714594
申请日:2003-11-14
CPC分类号: A61K35/19 , A61K35/28 , A61K35/32 , A61K35/33 , A61K38/1841 , A61K2300/00
摘要: The present invention relates to administering autologous uncultured cells into a diseased intervertebral disc.
摘要翻译: 本发明涉及将自体未培养的细胞施用于患病的椎间盘。
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12.Transdiscal administration of specific inhibitors of pro-inflammatory cytokines 有权
标题翻译: 跨时间给药促炎细胞因子的特异性抑制剂公开(公告)号:US20090175943A1
公开(公告)日:2009-07-09
申请号:US12291378
申请日:2008-11-07
申请人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Scott Bruder
发明人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Scott Bruder
IPC分类号: A61K9/10 , A61K39/395
CPC分类号: A61K35/28 , A61B5/055 , A61B17/7061 , A61K9/0012 , A61K9/0019 , A61K9/0085 , A61K35/32 , A61K38/17 , A61K38/1793 , A61K38/18 , A61K38/1841 , A61K38/1875 , A61K38/20 , A61K38/363 , A61K38/4833 , A61K39/395 , A61K39/3955 , A61K45/06 , A61K47/34 , C12Y304/21005 , G01N33/6869 , G01N2333/54
摘要: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.
摘要翻译: 本发明涉及将高特异性细胞因子拮抗剂注射到患病的椎间盘中。
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公开(公告)号:US07429378B2
公开(公告)日:2008-09-30
申请号:US10610355
申请日:2003-06-30
申请人: Hassan Serhan , Thomas M. DiMauro , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder , Laura J. Brown , Jeffrey C. Geesin
发明人: Hassan Serhan , Thomas M. DiMauro , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder , Laura J. Brown , Jeffrey C. Geesin
IPC分类号: A61K35/00
CPC分类号: A61K38/1841 , A61K35/28 , A61K38/57 , A61K2300/00
摘要: The present invention relates to injecting a high affinity antagonist of MMPs into a diseased intervertebral disc.
摘要翻译: 本发明涉及将MMP的高亲和力拮抗剂注射到患病的椎间盘中。
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公开(公告)号:US20080213261A1
公开(公告)日:2008-09-04
申请号:US11881926
申请日:2007-07-30
申请人: Thomas M. DiMauro , Hassan Serhan , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder
发明人: Thomas M. DiMauro , Hassan Serhan , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder
IPC分类号: A61K39/395 , A61K35/00 , A61P19/00 , A61K35/12
CPC分类号: A61K35/28 , A61B5/055 , A61B17/7061 , A61K9/0012 , A61K9/0019 , A61K9/0085 , A61K35/32 , A61K38/17 , A61K38/1793 , A61K38/18 , A61K38/1841 , A61K38/1875 , A61K38/20 , A61K38/363 , A61K38/4833 , A61K39/395 , A61K39/3955 , A61K45/06 , A61K47/34 , C12Y304/21005 , G01N33/6869 , G01N2333/54
摘要: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.
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公开(公告)号:US20070282300A1
公开(公告)日:2007-12-06
申请号:US11422222
申请日:2006-06-05
申请人: Mohamed Attawia , Cynthia Lee , Hassan Serhan , Michael O'Neil
发明人: Mohamed Attawia , Cynthia Lee , Hassan Serhan , Michael O'Neil
CPC分类号: A61B17/0218 , A61B17/3415 , A61B2017/00026 , A61B2017/00039 , A61B2017/00261 , A61B2017/0262 , A61F2/4611 , A61F2002/444 , A61F2002/4627
摘要: A pre-assembled, telescoping needle system comprising an outer needle surrounding a finer gauge needle which, after percutaneous penetration by the outer needle, extends to penetrate the intervertebral disc into which the injectable is to be delivered.
摘要翻译: 预组装的伸缩针系统,其包括围绕细针规的针的外针,所述外针经由外针的经皮穿透之后延伸以穿透待注射器将被输送到的椎间盘。
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16.
公开(公告)号:US20100268151A1
公开(公告)日:2010-10-21
申请号:US12727794
申请日:2010-03-19
申请人: Christoph Mauge , Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Jeffrey Sutton , Timothy Beardsley , Alan Dextradeur , Robert Kraus
发明人: Christoph Mauge , Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Jeffrey Sutton , Timothy Beardsley , Alan Dextradeur , Robert Kraus
IPC分类号: A61N5/06
CPC分类号: A61M27/006 , A61M25/0045 , A61M2025/0056 , A61N5/0601 , A61N5/062 , A61N2005/0651 , A61N2005/0659 , A61N2005/0661
摘要: An intracranial implant emitting light having a wavelength between blue and yellow light
摘要翻译: 发射具有蓝色和黄色光之间的波长的光的颅内植入物
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公开(公告)号:US08333960B2
公开(公告)日:2012-12-18
申请号:US12291016
申请日:2008-10-31
CPC分类号: A61K35/19 , A61K35/28 , A61K35/32 , A61K35/33 , A61K38/1841 , A61K2300/00
摘要: The present invention relates to administering autologous uncultured cells into a diseased intervertebral disc.
摘要翻译: 本发明涉及将自体未培养的细胞施用于患病的椎间盘。
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公开(公告)号:US08067397B2
公开(公告)日:2011-11-29
申请号:US12454200
申请日:2009-05-14
申请人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Gregory Collins , Laura J. Brown , Jeffrey C. Geesin
发明人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Gregory Collins , Laura J. Brown , Jeffrey C. Geesin
CPC分类号: A61K31/65 , A61K38/20 , A61K45/06 , A61K2300/00
摘要: The present invention relates to administering a doxycycline compound into a diseased intervertebral disc.
摘要翻译: 本发明涉及将多西环素化合物给予患病的椎间盘。
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公开(公告)号:US20100317948A1
公开(公告)日:2010-12-16
申请号:US12817585
申请日:2010-06-17
申请人: Thomas M. DiMauro , Jeffrey K. Sutton , Mohamed Attawia , Hassan Serhan , John Daniel Malone , Timothy Beardsley
发明人: Thomas M. DiMauro , Jeffrey K. Sutton , Mohamed Attawia , Hassan Serhan , John Daniel Malone , Timothy Beardsley
IPC分类号: A61B5/1459
CPC分类号: A61L31/146 , A61B17/866 , A61F2/30767 , A61F2/34 , A61F2/36 , A61F2/3662 , A61F2/38 , A61F2/4455 , A61F2002/30663 , A61F2002/30929 , A61F2002/30981 , A61F2002/3611 , A61F2002/3625 , A61F2002/443 , A61F2310/00023 , A61F2310/00604 , A61F2310/0061 , A61F2310/00616 , A61L27/06 , A61L27/427 , A61L27/56 , A61L31/022 , A61L31/124 , A61M5/158 , A61N5/0601 , A61N5/0624 , A61N2005/0651 , A61N2005/0661 , B01J35/004
摘要: An implant comprises a photocatalytic layer on at least one surface and is adapted to act as a sensor. In some embodiments, the photocatalytic layer is a semiconductor oxide that is doped. According to some embodiments, the implant comprises a wave guide. According to some embodiments the implant comprises a light port. According to some embodiments, the implant comprises a reflective material on a surface of the waveguide. According to some embodiments the implant comprises a composite material comprising a first material that has a transmissivity when exposed to a predetermined wavelength of light and a second material that has photocatalytic activity when exposed to the predetermined wavelength of light. According to some embodiments the implant comprises a light source adapted to irradiate the photocatalytic surface.
摘要翻译: 植入物包括在至少一个表面上的光催化层,并且适于作为传感器。 在一些实施方案中,光催化层是掺杂的半导体氧化物。 根据一些实施例,植入物包括波导。 根据一些实施例,植入物包括光端口。 根据一些实施例,植入物在波导的表面上包括反射材料。 根据一些实施例,植入物包括复合材料,其包括当暴露于预定波长的光时具有透射率的第一材料和当暴露于预定波长的光时具有光催化活性的第二材料。 根据一些实施例,植入物包括适于照射光催化表面的光源。
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公开(公告)号:US20090324558A1
公开(公告)日:2009-12-31
申请号:US12454200
申请日:2009-05-14
申请人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Gregory Collins , Laura J. Brown , Jeffrey C. Geesin
发明人: Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Gregory Collins , Laura J. Brown , Jeffrey C. Geesin
CPC分类号: A61K31/65 , A61K38/20 , A61K45/06 , A61K2300/00
摘要: The present invention relates to administering a doxycycline compound into a diseased intervertebral disc.
摘要翻译: 本发明涉及将多西环素化合物给予患病的椎间盘。
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