Anti-immunoresponsive polymeric material and its use in biological
applications
    13.
    发明授权
    Anti-immunoresponsive polymeric material and its use in biological applications 失效
    抗免疫反应性聚合物材料及其在生物应用中的应用

    公开(公告)号:US6071981A

    公开(公告)日:2000-06-06

    申请号:US163725

    申请日:1998-09-30

    摘要: A polymer composition comprising an anticoagulant carried in a water soluble polymer hydrogen bonded to a cellulose polymer. The composition is useful as sutures, implantable material, temporary grafts, vasculature connections and the like. The composition can be prepared by a method comprising the steps of: forming a solution in an amine oxide of a water-soluble polymer capable of hydrogen bonding, a cellulose polymer, and an anticoagulant and reducing the amount of amine oxide in the solution to solidify a solid polymer composition comprising the anticoagulant in the water soluble polymer and the cellulose polymer. The polymer compositions are particularly useful in temporary implants, sutures, grafts or the like.

    摘要翻译: 一种聚合物组合物,其包含携带在与纤维素聚合物结合的水溶性聚合物氢中的抗凝血剂。 该组合物可用作缝合线,可植入材料,临时移植物,脉管系统连接等。 组合物可以通过包括以下步骤的方法制备:在能够氢键合的水溶性聚合物的氧化胺中形成溶液,纤维素聚合物和抗凝剂并减少溶液中氧化胺的量以固化 包含水溶性聚合物中的抗凝血剂和纤维素聚合物的固体聚合物组合物。 聚合物组合物特别适用于临时植入物,缝线,移植物等。

    Surface modification of and dispersion of particles
    20.
    发明申请
    Surface modification of and dispersion of particles 审中-公开
    颗粒的表面改性和分散

    公开(公告)号:US20100068523A1

    公开(公告)日:2010-03-18

    申请号:US12283865

    申请日:2008-09-16

    IPC分类号: B05D7/00 B32B5/16

    CPC分类号: B01J2/30 Y10T428/2991

    摘要: A method provides a redispersible nanoparticle powder. The method includes: a) providing within a liquid carrier a first dispersion of nanoparticles having surface hydroxyl groups; b) adding a non-metal-ester molecular reactant for the hydroxyl group into the liquid carrier; c) reacting the reactant with the hydroxyl group to form individual, non-continuous sites having reaction product of the hydroxyl group and the reactant to form a surface treated nanoparticle; and d) drying the surface treated nanoparticle to at least reduce the presence of any excess non-metal-ester molecular reactant and providing non-aggregated powder of the surface treated nanoparticles such that when the dried, treated nanoparticle powder is redispersed as a second dispersion in a carrier or solvent having affinity for the non-metal-ester reactant product, a nano-sized particle is formed.

    摘要翻译: 一种方法提供可再分散的纳米颗粒粉末。 该方法包括:a)在液体载体内提供具有表面羟基的纳米颗粒的第一分散体; b)向液体载体中加入羟基的非金属酯分子反应物; c)使反应物与羟基反应以形成具有羟基和反应物的反应产物的单独的非连续位点以形成经表面处理的纳米颗粒; 和d)干燥经表面处理的纳米颗粒以至少减少任何过量的非金属酯分子反应物的存在并提供表面处理的纳米颗粒的非聚集粉末,使得当干燥的经处理的纳米颗粒粉末作为第二分散体再分散时 在对非金属 - 酯反应物产物具有亲和力的载体或溶剂中,形成纳米尺寸的颗粒。