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11.发明授权公开(公告)号：US07173704B2
公开(公告)日：2007-02-06
申请号：US10785411
申请日：2004-02-25
Applicant: Kazunori Yamauchi
Inventor： Kazunori Yamauchi
IPC: G01N21/00
CPC classification number: G01N30/90 , G01N21/474 , G01N21/78 , G01N21/8483 , G01N2201/064 , G01N2201/0813
Abstract: A measuring device for immunochromatography test piece comprising an irradiation optical system for irradiating measurement light onto an immunochromatography test piece, and a detection optical system for detecting reflected light from the immunochromatography test piece under irradiation with the measurement light. The irradiation optical system comprises a semiconductor light emitting element, a beam shaping member, a lens, a first baffle portion, a second baffle portion, and a third baffle portion. The beam shaping member shapes light from the semiconductor light emitting element, into a beam of a beam section extending in a direction substantially parallel to a colored line formed on the immunochromatography test piece. The lens focuses the beam from the beam shaping member on the immunochromatography test piece. The first baffle portion removes stray light, which is disposed between the semiconductor light emitting element and the beam shaping member. The second baffle portion removes stray light, which is disposed between the beam shaping member and the lens. The third baffle portion removes stray light, which is disposed between the lens and the immunochromatography test piece.
Abstract translation: 一种用于免疫层析试片的测量装置，包括用于将测量光照射到免疫层析试片上的照射光学系统，以及用于在用测量光照射下检测来自免疫层析试片的反射光的检测光学系统。 照射光学系统包括半导体发光元件，光束整形元件，透镜，第一挡板部分，第二挡板部分和第三挡板部分。 光束成形构件将来自半导体发光元件的光成形为沿与免疫层析试片上形成的彩色线基本平行的方向延伸的光束部分的光束。 透镜将来自光束成形构件的光束聚焦在免疫层析试片上。 第一挡板部分去除杂散光，其设置在半导体发光元件和光束成形构件之间。 第二挡板部分去除杂散光，其设置在光束成形构件和透镜之间。 第三挡板部分去除杂散光，其设置在透镜和免疫层析试片之间。
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公开(公告)号：US20030199758A1
公开(公告)日：2003-10-23
申请号：US10126026
申请日：2002-04-19
Inventor： Alan C. Nelson
IPC: A61B005/05
CPC classification number: G01N15/1475 , G01N15/147 , G01N21/4795 , G01N2015/1006 , G01N2015/1075 , G01N2015/1445 , G01N2201/0813 , G01N2223/612 , G06T11/006 , G06T2211/421
Abstract: Motion of an object of interest, such as a cell, has a variable velocity that can be varied on a cell-by-cell basis. Cell velocity is controlled in one example by packing cells into a capillary tube, or any other linear substrate that provides optically equivalent 360 degree viewing access, so that the cells are stationary within the capillary tube, but the capillary tube is translated and rotated mechanically through a variable motion optical tomography reconstruction cylinder. The capillary tube motion may advantageously be controlled in a start-and-stop fashion and translated and rotated at any velocity for any motion interval, under the control of a computer program. As such, there are several configurations of the optical tomography system that take advantage of this controlled motion capability. Additionally, the use of polarization filters and phase plates to reduce light scatter and diffraction background noise is described.
Abstract translation: 感兴趣对象（诸如单元）的运动具有可以逐个细胞的变化的可变速度。 在一个实例中，通过将细胞包装到毛细管或提供光学等效的360度观察通道的任何其它线性基质中，使细胞在毛细管内是固定的，但毛细管被平移并机械地旋转 可变运动光学层析成像圆筒。 在计算机程序的控制下，毛细管运动可以有利地以起始和停止的方式被控制并且以任何运动间隔的任何速度平移和旋转。 因此，存在利用该受控运动能力的光学层析成像系统的几种配置。 另外，描述了使用偏振滤光器和相位板来减少光散射和衍射背景噪声。
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公开(公告)号：US5237386A
公开(公告)日：1993-08-17
申请号：US761819
申请日：1991-09-20
Applicant: Phillip E. Harley
Inventor： Phillip E. Harley
CPC classification number: G01N21/8507 , G01N21/51 , G01J2001/4466 , G01J2005/062 , G01N2015/0238 , G01N21/53 , G01N2201/0813
Abstract: Apparatus for detecting particulates (46) within a medium in a chamber (10) comprises a photo-detector (14) which is maintained at a stable low temperature by a Peltier type cooling device (42). Scattered light from the particulate (46) is focused by a spherical lens (34) onto the input face (30) of a rod lens (22). The latter has an optical pitch of 0.5 and transfers the image to its output face (25) whence it passes via a light pipe (18) to the sensitive area (16) of the photo-electric device (14). The rod lens (22) provides an inexpensive means for transferring the light and which provides a thermal barrier. Thus, although the photo-electric device (14) is held at a low temperature, the input face (30) of the rod lens (22) can be held at the temperature of the medium within the chamber (10) and is not subjected to the formation of mist or ice. The lens (34) is mounted by means of a collar ( 28) which is slidable into a position in which the lens (34) focuses the input light into the face (30) of the lens (22), and then secured in this position by ultra-violet-cured adhesive fillets (32, 34).
Abstract translation: PCT No.PCT / GB90 / 00402 Sec。 371日期1991年9月20日 102（e）1991年9月20日PCT 1990年3月16日PCT公布。 WO90 / 11508 PCT公开号 日期：1990年10月4日。用于检测室（10）中的介质内的微粒（46）的装置包括通过珀尔帖型冷却装置（42）保持在稳定低温的光检测器（14）。 来自颗粒（46）的分散的光被球面透镜（34）聚焦到棒状透镜（22）的输入面（30）上。 后者具有0.5的光学间距，并且通过光管（18）将图像传送到其输出面（25）到光电装置（14）的敏感区域（16）。 棒状透镜（22）提供了用于传送光并且提供热障的廉价的装置。 因此，虽然光电装置（14）保持在低温，但是棒状透镜（22）的输入面（30）能够保持在室（10）内的介质的温度，并且不受 形成雾或冰。 透镜（34）借助于可滑动到透镜（34）将输入光聚焦到透镜（22）的表面（30）中的位置的轴环（28）安装，然后固定在该 由紫外线固化的胶片（32,34）定位。
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公开(公告)号：US4973844A
公开(公告)日：1990-11-27
申请号：US377942
申请日：1989-07-10
Applicant: Desmond J. O'Farrell , Kenneth L. Schierbeek
Inventor： Desmond J. O'Farrell , Kenneth L. Schierbeek
CPC classification number: B60S1/0822 , B60S1/0888 , G01N21/43 , B60S1/0833 , B60S1/0881 , G01N2201/0813
Abstract: A moisture sensing assembly, adapted for mounting on the inner surface of a vehicle window or windshield to control vehicle accessories such as windshield wipers, maximizes the window are a being sensed while minimizing the size of the overall assembly. In the preferred embodiment, moisture on the outer window surface is detected by stacked rows of infrared energy receiving sensors spaced in angular relationship from stacked rows of infrared energy emitting diodes. The emitter diodes and sensors are preferably carried in separate emitter and detector mounting blocks slidably fitted in a rigid carrier. The sensor row closest to the window receives energy from the diode emitter row farthest from the window and vice versa. Energy barrier walls are provided in the diode and sensor support for blocking energy reflected by the inside window surface. The assembly is adapted for use with an electrical circuit which operates one emitter diode row and its corresponding sensor row while the other emitter and sensor rows are deactivated to prevent interference and false reflected signals from the other emitter row. Removable attachment to the window with a circular member provides ease of installation and improved positioning and orientation of the sensing assembly.
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公开(公告)号：US4004150A
公开(公告)日：1977-01-18
申请号：US573766
申请日：1975-05-01
Applicant: Samuel Natelson
Inventor： Samuel Natelson
CPC classification number: G01N21/253 , G01N35/028 , G01N2201/0813
Abstract: The present invention contemplates an arrangement for analyzing a plurality of components in a single specimen which comprises placing a diluted specimen into a storage cup which is part of a sample carrier system, containing storage and reaction cups, transferring aliquots of the diluted solutions of the sample from the storage to the reaction cups, presenting the rows of the reaction cups to a work station, sequentially, adding a reagent to each of the reaction cups and moving the reaction cups into a work field where beams of light passing through the various reaction cups can be scanned and the components contained in the reaction cups can be assayed by means of a single detector attached to a computer and print-out system.
Abstract translation: 本发明考虑了一种用于分析单个样品中的多个组分的装置，其包括将稀释的样品放置在作为样品载体系统的一部分的储存杯中，所述储存杯包含储存和反应杯，转移样品的稀释溶液的等分试样 从储存器到反应杯，依次将反应杯排排列到工作站，向每个反应杯中加入试剂，并将反应杯移动到工作场中，其中通过各种反应杯的光束 可以扫描并且包含在反应杯中的组分可以通过连接到计算机和打印输出系统的单个检测器进行测定。
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Patent Agency Ranking
公开(公告)号：US3229513A
公开(公告)日：1966-01-18
申请号：US17494362
申请日：1962-02-23
Applicant: UNITED STATES STEEL CORP
Inventor： ROBERTS WILLIAM L
CPC classification number: G01N21/91 , B21B38/00 , G01N2201/0813
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公开(公告)号：US3191441A
公开(公告)日：1965-06-29
申请号：US22127562
申请日：1962-09-04
Applicant: SPERRY RAND CORP
Inventor： ERICKSON ROBERT A
IPC: B23K11/24
CPC classification number: B23K11/248 , G01N2201/0813
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公开(公告)号：US12117389B2
公开(公告)日：2024-10-15
申请号：US17487722
申请日：2021-09-28
Applicant: Cytiva Sweden AB
Inventor： Henrik Svanberg , Hanno Ehring , Erik Nils Ostlund
CPC classification number: G01N21/05 , G02B6/3616 , G02B6/3644 , G02B6/3825 , G02B6/3861 , G02B6/4219 , G01N2021/052 , G01N2201/0664 , G01N2201/0668 , G01N2201/0813 , G01N2201/086 , G02B6/36
Abstract: The present invention relates to an optical flow cell for a measuring device, having an input light guide with a light exit surface, an output light guide with a light entrance surface, said input light guide and output light guide being integrated with a holder to form an optical flow cell, and wherein the holder extends along a first axis and has a through hole for receiving a flow of a sample fluid, said through hole being transversal to said first axis, and the input light guide and output light guide further are arranged in said holder so that the light exit surface and the light entrance surface extend into said through hole and are arranged to be in optical alignment with each other and at a first distance from each other. The invention also relates to a measuring device having at least one optical flow cell.
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19.发明授权Method for correction of relative object-detector motion between successive views 有权在连续视图之间校正相对物体检测器运动的方法公开(公告)号：US07542597B2
公开(公告)日：2009-06-02
申请号：US11558593
申请日：2006-11-10
Applicant: John Richard Rahn , Alan C. Nelson
Inventor： John Richard Rahn , Alan C. Nelson
CPC classification number: G02B21/26 , G01N15/1468 , G01N15/147 , G01N15/1475 , G01N21/05 , G01N21/4795 , G01N2015/1006 , G01N2015/1075 , G01N2021/0346 , G01N2021/1787 , G01N2201/0813 , G01N2223/612 , G02B21/365 , G06T11/005 , G06T11/006 , G06T2211/412 , G06T2211/421
Abstract: An apparatus and method for correction of relative object-detector motion between successive views during optical tomographic imaging in three dimensions. An object of interest is illuminated to produce an image. A lateral offset correction value is determined for the image. An axial offset correction value is determined for the image. The lateral offset correction value and the axial offset correction value are applied to the image to produce a corrected file image.
Abstract translation: 一种用于在三维尺度下在光学层析成像期间校正连续视图之间的相对物体检测器运动的装置和方法。 感兴趣的对象被照亮以产生图像。 确定图像的横向偏移校正值。 为图像确定轴向偏移校正值。 将横向偏移校正值和轴向偏移校正值应用于图像以产生校正的文件图像。
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公开(公告)号：US07197355B2
公开(公告)日：2007-03-27
申请号：US10126026
申请日：2002-04-19
Applicant: Alan C. Nelson
Inventor： Alan C. Nelson
IPC: A61B5/05
CPC classification number: G01N15/1475 , G01N15/147 , G01N21/4795 , G01N2015/1006 , G01N2015/1075 , G01N2015/1445 , G01N2201/0813 , G01N2223/612 , G06T11/006 , G06T2211/421
Abstract: Motion of an object of interest, such as a cell, has a variable velocity that can be varied on a cell-by-cell basis. Cell velocity is controlled in one example by packing cells into a capillary tube, or any other linear substrate that provides optically equivalent 360 degree viewing access, so that the cells are stationary within the capillary tube, but the capillary tube is translated and rotated mechanically through a variable motion optical tomography reconstruction cylinder. The capillary tube motion may advantageously be controlled in a start-and-stop fashion and translated and rotated at any velocity for any motion interval, under the control of a computer program. As such, there are several configurations of the optical tomography system that take advantage of this controlled motion capability. Additionally, the use of polarization filters and phase plates to reduce light scatter and diffraction background noise is described.
Abstract translation: 感兴趣对象（诸如单元）的运动具有可以逐个细胞的变化的可变速度。 在一个实例中，通过将细胞包装到毛细管或提供光学等效的360度观察通道的任何其它线性基质中，使细胞在毛细管内是固定的，但毛细管被平移并机械地旋转 可变运动光学层析成像圆筒。 在计算机程序的控制下，毛细管运动可以有利地以起始和停止的方式被控制并且以任何运动间隔的任何速度平移和旋转。 因此，存在利用该受控运动能力的光学层析成像系统的几种配置。 另外，描述了使用偏振滤光器和相位板来减少光散射和衍射背景噪声。
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