公开(公告)号：US20030206825A1

公开(公告)日：2003-11-06

申请号：US10454583

申请日：2003-06-05

Inventor： Arthur L. Vellutato

IPC: A61L002/00 ,  B01J019/00

CPC classification number: A61L2/081 ,  A61L2/0011 ,  A61L2/0035

Abstract: A sterilized chemical composition is stored in a sterile environment for a prolonged period of time, hermetically sealed in successive enclosures and a shipping enclosure. The third sealing layer is removed prior to entering a storage area. The second layer is removed prior to taking the container to the sterile environment. The storage area may also be sterile. The innermost container may be an aerosol container and the composition a disinfectant liquid such as alcohol. The entire shipping enclosure and contents is preferably sterilized with gamma radiation.

Abstract translation: 将灭菌的化学组合物在无菌环境中长时间储存​​，密封在连续的外壳和运输箱中。 第三密封层在进入存储区域之前被去除。 在将容器带到无菌环境之前，将第二层除去。 存储区域也可以是无菌的。 最内容器可以是气溶胶容器，组合物是诸如酒精的消毒液体。 整个运输外壳和内容物优选用γ辐射灭菌。

公开(公告)号：US20030185703A1

公开(公告)日：2003-10-02

申请号：US10106789

申请日：2002-03-26

Inventor： James L. Walsh

IPC: A61L002/08 ,  B01J019/00

CPC classification number: B29C65/7451 ,  A61L2/07 ,  A61L2/26 ,  A61L2202/24 ,  B29C65/223 ,  B29C66/0044 ,  B29C66/1122 ,  B29C66/4312 ,  B29C66/8161 ,  B29C66/8221 ,  B29C66/8324 ,  B29C66/861 ,  B65B51/148 ,  B65B61/06

Abstract: A method for preparing dental instruments for sterilization in which the instruments are put into a relatively large see-through heat sealable plastic bag. The bag is placed over a surface of an impulse heater and an arm is lowered to clamp the bag and apply two heat seals across the bag; one heat seal to enclose the instruments and a second parallel heat seal. A knife carried by the arm is used to cut between the two heat seals. This cutting operation forms a custom sized closed bag containing the instruments to be sterilized that is placed into an autoclave and sterilized. The cutting also forms a second bag, smaller than the original bag that is reserved for use in a subsequent packaging operation.

Abstract translation: 一种用于制备用于灭菌的牙科器械的方法，其中将器械放入相对较大的透明可热封塑料袋中。 将袋放置在脉冲加热器的表面上，并且将臂降低以夹紧袋并且在袋上施加两个热密封; 一个热封封闭仪器和一个第二平行热封。 使用由手臂承载的刀在两个热封之间切割。 该切割操作形成定制尺寸的封闭的袋子，该袋子将待灭菌的仪器放入高压灭菌器并进行灭菌。 切割还形成第二个袋子，比原来的袋子小，以备后续包装操作使用。

公开(公告)号：US20030161763A1

公开(公告)日：2003-08-28

申请号：US10348220

申请日：2003-01-21

Applicant: Symyx Technologies, Inc.

Inventor： Lynn Van Erden ,  William H. Chandler JR.

IPC: B01J019/00

CPC classification number: B01L3/5025 ,  B01J3/04 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/0031 ,  B01J2219/00315 ,  B01J2219/00335 ,  B01J2219/00337 ,  B01J2219/00418 ,  B01J2219/00423 ,  B01J2219/00477 ,  B01J2219/00585 ,  B01J2219/00601 ,  B01J2219/00704 ,  B01J2219/0072 ,  B01J2219/00736 ,  G01N35/028

Abstract: An apparatus and method for synthesis and screening of materials are disclosed. According to one aspect of the present invention, a parallel batch reactor for effecting chemical reactions includes a pressure chamber, an inlet port, and two or more reaction vessels within the pressure chamber. The inlet port is in fluid communication with the pressure chamber, and is used for pressurizing the pressure chamber from an external pressure source. Each of the two or more reaction vessels are in isolatable fluid communication with the pressure chamber such that during a first pressurizing stage of operation, each of the two or more reaction vessels can be simultaneously pressurized through common fluid communication with the pressure chamber. In addition, during at least a second reaction stage of operation, each of the two or more pressurized reaction vessels can be isolated from each other.

Abstract translation: 公开了一种合成和筛选材料的装置和方法。 根据本发明的一个方面，用于实现化学反应的并行批量反应器包括压力室，入口和压力室内的两个或更多个反应容器。 入口与压力室流体连通，用于从外部压力源对压力室进行加压。 两个或更多个反应容器中的每一个与压力室可分离流体连通，使得在操作的第一加压阶段期间，两个或更多个反应容器中的每一个可以通过与压力室的常见流体连通同时加压。 此外，在操作的至少第二反应阶段期间，两个或更多个加压反应容器中的每一个可以彼此隔离。

公开(公告)号：US20030161755A1

公开(公告)日：2003-08-28

申请号：US10085577

申请日：2002-02-26

Applicant:

Inventor： Victoria M. Richards

IPC: A61L009/00 ,  B01J019/00

CPC classification number: A61L9/02 ,  A61L9/03

Abstract: Disclosed is an oil lamp disperser and an oil lamp that disperses a volatile material from a fuel and volatile material mixture while the oil lamp is burning. The volatile material is released from the surface of an emanator element as the fuel and volatile material mixture passes through the emanator element prior to reaching the flame of the lamp. Proper construction of the lamp allows the lamp to volatilize substantial amounts of the volatile material into the surrounding environment.

公开(公告)号：US20030152492A1

公开(公告)日：2003-08-14

申请号：US10379291

申请日：2003-03-03

Applicant: Cepheid

Inventor： Ronald Chang ,  Lee A. Christel ,  Gregory T.A. Kovacs ,  William A. McMillan ,  M. Allen Northrup ,  Kurt E. Petersen ,  Farzad Pourahmadi ,  Steven J. Young ,  Robert Yuan ,  Douglas B. Dority

IPC: B01J019/00

CPC classification number: B01L3/508 ,  B01J19/0093 ,  B01J2219/00804 ,  B01J2219/0081 ,  B01J2219/00873 ,  B01J2219/0097 ,  B01L7/52 ,  B01L2300/042 ,  B01L2300/0809 ,  B01L2300/0858 ,  B01L2300/168 ,  B01L2300/1805 ,  F28D2021/0077 ,  F28F3/12 ,  F28F21/04 ,  F28F2280/10 ,  G01N21/0303 ,  G01N21/0332 ,  G01N2035/00326

Abstract: This invention provides an apparatus for rapidly heating and/or cooling a sample in a reaction vessel. In some embodiments, the apparatus includes optics for the efficient detection of a reaction product in the vessel. The invention also provides a reaction vessel having a reaction chamber designed for optimal thermal conductance and for efficient optical viewing of reaction products in the chamber.

Abstract translation: 本发明提供一种用于在反应容器中快速加热和/或冷却样品的装置。 在一些实施例中，该装置包括用于有效检测容器中的反应产物的光学元件。 本发明还提供一种反应容器，该反应容器具有设计用于最佳热传导和有效地光学观察室内反应产物的反应室。

公开(公告)号：US20030144127A1

公开(公告)日：2003-07-31

申请号：US10168709

申请日：2002-09-09

Inventor： Eva Berggren ,  Dag Lindstrom

IPC: B01J019/00

CPC classification number: B01J20/285 ,  B01J20/26 ,  B01J20/261 ,  B01J20/262 ,  B01J20/267 ,  B01J20/28011 ,  B01J20/28016 ,  B01J20/28042 ,  B01J2219/00497 ,  B01J2220/52 ,  B01J2220/82 ,  C07B2200/11 ,  C07K1/042 ,  C07K1/16 ,  C08J3/28 ,  C12N5/0068 ,  C12N2533/76 ,  C12N2533/78

Abstract: A method for the production of a cross-linked support matrix that in form of a bed will permit liquid flow velocities above 5 cm/h, preferably above 50 cm/h, to pass through the bed. The method is characterized in that it comprises the steps: (a) providing a starting support matrix that has pendent unsaturated groups, and (b) subjecting said starting support matrix to electron beam or gamma-ray irradiation. The use of a cross-linked support matrix produced by a method comprising the steps of: (a) providing a starting support matrix that has pendent unsaturated groups, and (b) subjecting said starting support matrix to electron beam or gamma-ray irradiation as a support matrix in liquid chromatography, cell culturing, step-wise solid phase synthesis of organic compounds, running catalytic reactions by the use of a solid phase bound catalyst.

Abstract translation: 用于生产以床形式的交联载体基质的方法将允许高于5cm / h，优选地高于50cm / h的液体流速通过床。 该方法的特征在于其包括以下步骤：（a）提供具有侧链不饱和基团的起始载体基质，和（b）使所述起始载体基质经受电子束或γ射线照射。 使用通过包括以下步骤的方法产生的交联载体基质：（a）提供具有侧链不饱和基团的起始载体基质，和（b）使所述起始载体基质进行电子束或γ射线照射， 液相色谱法中的支持基质，细胞培养，有机化合物的逐步固相合成，通过使用固相结合的催化剂进行催化反应。

公开(公告)号：US20030143121A1

公开(公告)日：2003-07-31

申请号：US10057459

申请日：2002-01-25

Inventor： Joseph Nolfo ,  Maxine Soumellant ,  Victor W. Rosso ,  Peter Lee ,  Mayra B. Reyes ,  John J. Venit

IPC: B01J019/00

CPC classification number: B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00389 ,  B01J2219/00477 ,  B01J2219/00481 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00601 ,  B01J2219/00698 ,  B01J2219/00745 ,  B01J2219/00747 ,  C40B30/08 ,  C40B40/18 ,  C40B60/14

Abstract: Multiple parallel chemical reactions are performed under pressure in a reactor including a multi-row array of reaction vessels situated between a temperature control base and a fluid flow manifold. The manifold consists of an input portion connected to the fluid supply by a five-way valve and a distribution portion which includes separate parallel distribution channels, one for each row of reaction vessels. A control valve for each distribution channel is interposed between the manifold portions such that the fluid flow to each row of reaction vessels can be independently controlled. An explosion proof transparent shield can be situated between the base and manifold, surrounding the reaction vessels. The interior of the shield can be flooded with inert gas.

Abstract translation: 在包括位于温度控制基底和流体流动歧管之间的反应容器的多列阵列的反应器中，在压力下进行多个平行化学反应。 歧管由通过五通阀连接到流体供应器的输入部分和分配部分组成，分配部分包括单独的平行分配通道，每排反应容器一个。 用于每个分配通道的控制阀插入在歧管部分之间，使得可以独立地控制到每排反应容器的流体流动。 防爆透明屏蔽可位于基座和歧管之间，围绕反应容器。 屏蔽内部可以充满惰性气体。

公开(公告)号：US20030138347A1

公开(公告)日：2003-07-24

申请号：US10029532

申请日：2001-12-21

Inventor： Szu-Min Lin

IPC: A61L009/00 ,  B01J019/00 ,  A62B007/08 ,  B01D011/02 ,  A61L002/00

CPC classification number: A61L2/208 ,  A61L2/24 ,  A61L2/26 ,  A61L2/28 ,  A61L2202/122 ,  A61L2202/14 ,  Y10T436/196666

Abstract: A sterilization system employs an attachable/detachable container to which is connected a source of sterilant for sterilizing items within the container. When disconnected from the source of sterilant the container is sealed from microbial ingress.

Abstract translation: 灭菌系统采用可连接/可拆卸的容器，其连接有用于对容器内的物品进行消毒的消毒剂源。 当与灭菌源断开连接时，容器与微生物入口密封。

公开(公告)号：US20030118482A1

公开(公告)日：2003-06-26

申请号：US10035788

申请日：2001-12-24

Inventor： Bill J. Peck

IPC: B01J019/00

CPC classification number: B82Y30/00 ,  B01J19/0046 ,  B01J2219/00286 ,  B01J2219/00378 ,  B01J2219/00389 ,  B01J2219/00423 ,  B01J2219/00477 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00608 ,  B01J2219/00659 ,  B01J2219/00675 ,  B01J2219/00689 ,  B01J2219/00691 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00731 ,  C40B40/06 ,  C40B40/10 ,  C40B40/12 ,  C40B50/14 ,  C40B60/14

Abstract: Apparatus and methods are disclosed for controlling atmospheric characteristics inside a chamber. An apparatus comprises a mechanism for diffusively introducing pressurized gas into the apparatus, an outlet element in fluid communication with the mechanism, and a chamber in fluid communication with the outlet element. The outlet element and the chamber are disposed such that gas flow therethrough is substantially uniform. The chamber comprises a gas outlet and the outlet element comprises a plurality of openings. The apparatus may be employed in the manufacture of biopolymers on the surface of a support such as an array of biopolymer features on the support.

Abstract translation: 公开了用于控制室内的大气特性的装置和方法。 一种装置包括用于将加压气体扩散入设备的机构，与该机构流体连通的出口元件，以及与出口元件流体连通的室。 出口元件和室被布置成使得其中的气体流动基本上是均匀的。 该室包括气体出口，出口元件包括多个开口。 该装置可以用于在载体的表面上制造生物聚合物，例如载体上生物聚合物特征的阵列。

公开(公告)号：US20030049163A1

公开(公告)日：2003-03-13

申请号：US09428207

申请日：1999-10-27

Inventor： PAUL S. MALCHESKY ,  CHRISTOPHER M. FRICKER

IPC: A61L002/00 ,  A61L009/00 ,  B01J019/00 ,  C23F011/18 ,  B01J019/08

CPC classification number: C23F11/00 ,  A61L2/035 ,  C02F1/4618 ,  C02F1/4674

Abstract: An anticorrosive, penetration enhancing composition for cleaning decontaminating and rinsing includes electrochemically activated (ECA) water as the decontamination agent. The anticorrosive decontamination composition has, as the anticorrosive agent, a compound or mixture of compounds capable of inhibiting corrosion of various metals used in sterilization decontamination and rinsing systems and objects such as medical instruments. Preferred anticorrosive compounds include phosphates, azoles, and sulfates. Other additives, including wetting agents, are added to reduce the surface energy of the ECA water. This reduced surface energy permits the ECA water to penetrate into objects of complex design thus permitting complete decontamination of the treated object.

Abstract translation: 用于清洁净化和漂洗的防腐，渗透增强组合物包括作为去污剂的电化学活化（ECA）水。 作为防锈剂，防腐去污组合物具有能够抑制灭菌去污和漂洗系统等各种金属的腐蚀化合物或化合物的混合物，医疗器械等物品。 优选的防腐化合物包括磷酸盐，唑类和硫酸盐。 加入其他添加剂，包括润湿剂，以降低ECA水的表面能。 这种减少的表面能量允许ECA水渗透到复杂设计的对象中，从而允许对被处理物体的完全去污。