公开(公告)号：US20080218732A1

公开(公告)日：2008-09-11

申请号：US11996103

申请日：2006-07-24

Applicant: Samson Mil'shtein ,  Niyom Lue

Inventor： Samson Mil'shtein ,  Niyom Lue

IPC: A61B6/00

CPC classification number: A61B5/0059 ,  A61B6/508 ,  G01J3/10 ,  G01J3/45 ,  G01N21/274 ,  G01N21/359

Abstract: Methods and systems for generating near-infrared (NIR) images of biological targets are discussed. In one aspect, one or more radiation sources illuminate a target, with one or more detectors receiving the transmitted radiation. Such equipment can be used to generate a plurality of NIR images of a target. The images can be converted into frequency space, combined using chosen weighting factors, and deconvoluted into the spatial domain to provide a composite image. The composite image can have enhanced quality relative to the individual images, allowing for a richer set of information to be displayed. Other aspects such as scanning, background illumination correction, the use of filters, and additional techniques are also discussed.

Abstract translation: 讨论了用于生成生物目标的近红外（NIR）图像的方法和系统。 在一个方面，一个或多个辐射源照射目标，一个或多个检测器接收所发射的辐射。 这样的设备可以用于产生目标的多个NIR图像。 可以将图像转换成频率空间，使用选择的加权因子组合，并解卷积到空间域中以提供合成图像。 合成图像可以相对于各个图像具有增强的质量，允许显示更丰富的信息。 还讨论了诸如扫描，背景照明校正，滤波器的使用以及附加技术的其他方面。

公开(公告)号：US07391519B1

公开(公告)日：2008-06-24

申请号：US11451310

申请日：2006-06-13

Applicant: Richard L. Kendrick ,  Eric H. Smith

Inventor： Richard L. Kendrick ,  Eric H. Smith

IPC: G01B9/02

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/2803 ,  G01J3/45 ,  G01J9/02

Abstract: Detecting the presence of a target material in a scene by using a multi-aperture interferometer system having a plurality of apertures at least one of which has an adjustable optical path length, by adjusting the aperture(s) to obtain a predetermined optical path length difference among the apertures, the predetermined optical path length difference being based on a source laser wavelength and a target material wavelength, illuminating the scene with the source laser, capturing a spectral data set corresponding to an interference pattern generated in the multi-aperture interferometer system for an illuminated point source in the scene, the spectral data set containing spatially distributed spectral data, and determining whether the target material is present at the illuminated point source based on a presence of spectral data in at least one side lobe of the spectral data set.

Abstract translation: 通过使用具有多个孔径的多孔径干涉仪系统来检测场景中的目标材料的存在，所述多孔径干涉仪系统中的至少一个具有可调整的光程长度，通过调整孔径以获得预定的光程长度差 在所述孔之间，所述预定光程长度差基于源激光波长和目标材料波长，用所述源激光照射所述场景，捕获与所述多孔径干涉仪系统中生成的干涉图案相对应的光谱数据集，用于 场景中的照明点源，包含空间分布的光谱数据的光谱数据集，以及基于光谱数据集的至少一个旁瓣中的光谱数据的存在来确定目标材料是否存在于照明点源。

公开(公告)号：US20070127030A1

公开(公告)日：2007-06-07

申请号：US11677185

申请日：2007-02-21

Applicant: Isaac Shpantzer

Inventor： Isaac Shpantzer

IPC: G01B9/02 ,  G01J3/45

CPC classification number: G01N21/171 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0224 ,  G01J3/45 ,  G01J9/04 ,  G01N2021/1793 ,  G02B26/06

Abstract: A photo-thermal interferometric spectroscopy system is disclosed that provides information about a chemical at a remote location. A first light source assembly is included that emits a first beam. The first beam has one or more wavelengths that interact with the chemical and change a refractive index of the chemical. A second laser produces a second beam. The second beam interacts with the chemical resulting in a third beam with a phase change that corresponds with the change of the refractive index of the chemical. A detector system is positioned remote from the chemical to receive at least a portion of the third beam. An adaptive optics system at least partially compensates the light beam degradation caused by atmospheric turbulence. A focusing system is used to bring together the light passed through the chemical; the focusing system includes a multimode fiber for the light collection, The detector system provides information on a phase change in the third beam relative to the second beam that is indicative of at least one of, absorption spectrum and concentration of the chemical.

Abstract translation: 公开了一种在远程位置提供关于化学品的信息的光热干涉光谱系统。 包括发射第一光束的第一光源组件。 第一光束具有与化学物质相互作用并改变化学物质折射率的一种或多种波长。 第二激光器产生第二光束。 第二束与化学物质相互作用，导致具有与化学物质的折射率变化相对应的相变的第三光束。 检测器系统定位成远离化学品以接收第三束的至少一部分。 自适应光学系统至少部分补偿由大气湍流引起的光束退化。 聚焦系统用于将通过化学品的光汇集在一起​​; 聚焦系统包括用于光收集的多模光纤。检测器系统提供关于相对于第二光束的第三光束相变的信息，其指示化学品的吸收光谱和浓度中的至少一个。

公开(公告)号：US20070125950A1

公开(公告)日：2007-06-07

申请号：US11548414

申请日：2006-10-11

Applicant: Hai-Shui Wang ,  Junzo Umemura

Inventor： Hai-Shui Wang ,  Junzo Umemura

IPC: G01J5/02

CPC classification number: G01J3/02 ,  G01J3/0286 ,  G01J3/0297 ,  G01J3/45 ,  G01N21/3504 ,  G01N2021/3595

Abstract: A convenient and economical method and instrumentation to efficiently reduce offensive spectral noises due to water vapor and carbon dioxide gas often encountered in FTIR spectrophotometry is provided by spectrally monitoring and controlling the amount of water vapor and carbon dioxide gas inside the spectrophotometer such that both amounts in the sample and background measurements become congruent through remote open-close operation of water-vapor (or carbon dioxide gas) supplier and dehumidifier (or carbon dioxide gas adsorber). This new technique can be used: (1) Under the ambient humidity condition, saving time and money effectively. (2) Both in the closed spectrophotometer and in the open system. (3) And applicable to any FTIR accessory and measurement method, including transmission, external reflection, reflection-absorption, attenuated total reflection (ATR), and microscopy measurements.

Abstract translation: 通过光谱监测和控制分光光度计内的水蒸气和二氧化碳气体的量，提供了一种方便和经济的方法和仪器，可有效降低由于FTIR分光光度法中经常遇到的水蒸汽和二氧化碳气体造成的进一步的光谱噪声， 样品和背景测量通过水蒸汽（或二氧化碳气体）供应商和除湿机（或二氧化碳气体吸附器）的远程打开关闭操作变得一致。 可以使用这种新技术：（1）在环境湿度条件下，有效节省时间和金钱。 （2）在封闭分光光度计和开放系统中。 （3）适用于任何FTIR附件和测量方法，包括透射，外反射，反射吸收，衰减全反射（ATR）和显微镜测量。

公开(公告)号：US20060250616A1

公开(公告)日：2006-11-09

申请号：US11478804

申请日：2006-06-30

Applicant: Kenneth Pettipiece ,  William Amos

Inventor： Kenneth Pettipiece ,  William Amos

IPC: G01B9/02 ,  G01J3/45

CPC classification number: G01J3/2823 ,  G01J3/45 ,  G01J2003/2866

Abstract: A method and apparatus for an improved spectral imaging system is provided. The system is capable of measuring the fluorescence, luminescence, or absorption at selected locations on a sample plate. The emissions detection subassembly can tune to any wavelength within a continuum of wavelengths utilizing an interferometric spectral discriminator. The interferometric spectral discriminator creates an interferogram from which the wavelength spectra for each pixel of the array can be calculated, typically using Fourier transform analysis. In one aspect, the chromatic accuracy of the system is calibrated using a calibration slit placed in the input aperture of the input relay lens but outside of the sample image. The slit is illuminated using a source of known wavelength. The fringe count versus the wavelength of the slit illumination source is monitored and used to calibrate the spectral discriminator. In another aspect, a transparent optic is included in the interferometric spectral discriminator that can be inserted into the beam path whenever a monochrome image of the sample is required. The optic produces a large offset in the legs of the interferometer resulting in the fringe density becoming too large to resolve by the individual pixels of the detector array. In another aspect, the interferometric spectral discriminator includes a polarizing beam splitter. The polarizing beam splitter preferentially reflects one polarization while preferentially transmitting a second polarization, thus achieving improved efficiency while minimizing ghosting. In another aspect, a metaphase finder is used to locate areas of interest. The sample plate containing the material of interest is illuminated with light of a wavelength determined to preferentially scatter from objects the size of the metaphase spreads. The intensity of the scattered light versus the location on the sample plate is monitored and used to locate the areas of interest. Preferably the sample plate is also illuminated by light of a second wavelength which is not preferentially scattered by the objects of interest, thus representing the background scatter. By subtracting the background scatter from the primary scattered light, improved object discrimination is achieved.

公开(公告)号：US20050036145A1

公开(公告)日：2005-02-17

申请号：US10481942

申请日：2002-04-23

Applicant: Hiromu Meada ,  Toshihiro Mizuno

Inventor： Hiromu Meada ,  Toshihiro Mizuno

IPC: G01J3/02 ,  G01J3/26 ,  G01J3/28 ,  G01J3/36 ,  G01J3/45

CPC classification number: G01J3/2803 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/26 ,  G01J3/36 ,  G01J3/45 ,  G01N21/3563

Abstract: A small packaged spectroscopic sensor unit is provided which measures or inspects an interior quality or ingredient of an inspection object by introducing light having passed through the interior of the inspection object to an optical fiber and analyzes the light spectroscopically. In this sensor unit, the fiber bundle receives only a light beam of incident angle less than a prescribed angle, the fiber bundle is twisted together to disperse and uniformize the irregularity of the introduced light at the light-emitting end, and the optical fiber bundle is held by an arranging holder to shape the light-emitting face of the fiber bundle to fit the light-receiving face of a light diffuser and the light-receiving face of a photoelectric conversion element. The sensor unit has a light diffuser for diffuse-transmitting the light emitted from the light-emitting face of the optical fiber bundle, a continuous variable interference filter placed on the light-emitting face of the light diffuser, and a photoelectric conversion element after the continuous variable interference filter. The optical paths of the optical fiber bundle, light diffuser, and the continuous variable interference filter are aligned to be connected. The above members are sealed airtightly in a package.

Abstract translation: 提供了一种小包装的光谱传感器单元，其通过将通过检查对象的内部的光引入光纤来测量或检查检查对象的内部质量或成分，并对光进行光谱分析。 在该传感器单元中，纤维束仅接收入射角小于规定角度的光束，将纤维束扭转在一起，使发光端的引入光的不规则性分散均匀化，光纤束 由布置保持器保持以使光纤束的发光面成形，以配合光漫射体的光接收面和光电转换元件的光接收面。 传感器单元具有用于漫射透射从光纤束的发光面发射的光的光扩散器，放置在光扩散器的发光面上的连续可变干涉滤光器，以及后置的光电转换元件 连续可变干涉滤波器 将光纤束，光扩散器和连续可变干涉滤光器的光路对齐以进行连接。 上述构件密封地密封在包装中。

公开(公告)号：US20050018197A1

公开(公告)日：2005-01-27

申请号：US10896276

申请日：2004-07-21

Applicant: Josh Hogan

Inventor： Josh Hogan

IPC: G01J3/45

CPC classification number: G01J3/45

Abstract: A spectral analysis system includes a signal processing system which provides a probe and a reference beam. The probe beam is applied to the target to be analyzed. The relative phase relationship of the two beams is varied. A scattered or transmitted portion of the probe beam is combined with the reference beam and a resulting interferometric signal is detected. An electronic processing and control system separates the spectral information in the electronic domain, processes the information and controls the system.

Abstract translation: 光谱分析系统包括提供探针和参考光束的信号处理系统。 将探测光束施加到要分析的靶上。 两个光束的相对相位关系是变化的。 将探测光束的散射或透射部分与参考光束组合，并检测所得到的干涉信号。 电子处理和控制系统分离电子领域的光谱信息，处理信息并控制系统。

公开(公告)号：US06744517B1

公开(公告)日：2004-06-01

申请号：US09719215

申请日：2001-02-26

Applicant: Colin Forno ,  Maurice Whelan

Inventor： Colin Forno ,  Maurice Whelan

IPC: G01B902

CPC classification number: G01B11/161 ,  G01B9/02032 ,  G01B9/02087 ,  G01J3/45

Abstract: An interferometer (1) is arranged to form a first interference fringe pattern comprising at least ten interference fringes; recording an image of said first interference fringe pattern; perturbing an optical path in the interferometer (1) to form a second interference fringe pattern comprising at least ten interference fringes; and combining an image of said second interference fringe pattern with the recorded image of the first interference fringe pattern to produce a further image comprising a moiré fringe pattern arising from a difference or differences between the first and second interference fringe patterns. The combining step involves subtraction (4) of digital images. Different wavelengths and interferometers are used: Michelson, Mach-Zehnder, Fizeau, Twyman-Green. In this new approach, all the errors of a poor quality, misaligned system are accepted and then eliminated by the combination process, producing a moiré fringe pattern. The method enables very large aperture optical systems for traditional and engineering interferometers to be constructed from inexpensive and basic components.

Abstract translation: 干涉仪（1）布置成形成包括至少十个干涉条纹的第一干涉条纹图案; 记录所述第一干涉条纹图案的图像; 扰乱干涉仪（1）中的光路以形成包括至少十个干涉条纹的第二干涉条纹图案; 以及将所述第二干涉条纹图案的图像与所述第一干涉条纹图案的记录图像组合以产生包括由所述第一和第二干涉条纹图案之间的差异或差异产生的莫尔条纹图案的另外的图像。 组合步骤涉及数字图像的减法（4）。 使用不同的波长和干涉仪：Michelson，Mach-Zehnder，Fizeau，Twyman-Green。 在这种新方法中，质量差，不对准的系统的所有错误都被接受，然后通过组合过程消除，产生莫尔条纹模式。 该方法使得用于传统和工程干涉仪的非常大的孔径光学系统由廉价和基本的部件构成。

公开(公告)号：US20040061862A1

公开(公告)日：2004-04-01

申请号：US10256794

申请日：2002-09-27

Inventor： Alan Ross ,  Edwin D. Tucker

IPC: G01B009/02 ,  G01J003/45

CPC classification number: G01J3/45 ,  G01B2290/35 ,  G02B7/004

Abstract: A linear positioning apparatus includes an intermediate portion having an axis, and first and second end portions mounted with flexure legs thereto. The flexure legs accommodate motion of the intermediate portion relative to the end portions along the axis, but inhibit motion of the intermediate portion relative to the end portions in directions not parallel to the axis. The apparatus can accommodate forces having off-axis components, and produce motion that comprises substantially no off-axis component. The apparatus is useful in, for example, optical systems where precise linear motion is required.

Abstract translation: 线性定位装置包括具有轴的中间部分，以及安装有弯曲腿的第一和第二端部。 弯曲腿容纳中间部分相对于沿着轴线的端部的运动，但是阻止中间部分相对于端部在不平行于轴线的方向上的运动。 该装置可以适应具有离轴部件的力，并且产生基本上不包括离轴部件的运动。 该装置在例如需要精确的线性运动的光学系统中是有用的。

公开(公告)号：US06624894B2

公开(公告)日：2003-09-23

申请号：US09888826

申请日：2001-06-25

Applicant: Artur Olszak ,  Joanna Schmit

Inventor： Artur Olszak ,  Joanna Schmit

IPC: G01B1102

CPC classification number: G01B11/2441 ,  G01B9/02057 ,  G01B9/02071 ,  G01B9/0209 ,  G01B2290/60 ,  G01J3/45

Abstract: A reference signal is used to track the actual behavior of the scanner in an interferometer to produce scanner-position data that can be used to correct errors introduced by scanner nonlinearities and other error sources. A narrow-band light source is advantageously utilized to cover the entire range of operation of the scanner. Because of the independent reference channel, the invention is suitable for implementation with all types of conventional interferometric techniques. The concept is preferably implemented by utilizing an additional light source and the same scanner used for the measurement, so that the OPD varies in synchronization of both the reference-signal and data-collection procedures. Alternatively, a high temporal-coherence filter may be used with the same light source and optical path used for the interferometric measurement.

Abstract translation: 参考信号用于跟踪扫描仪在干涉仪中的实际行为，以产生可用于校正扫描仪非线性和其他错误源引入的误差的扫描仪位置数据。 有利地，窄带光源用于覆盖扫描仪的整个操作范围。 由于独立的参考通道，本发明适用于所有类型的常规干涉技术的实现。 该概念优选地通过利用附加光源和用于测量的相同扫描器来实现，使得OPD在参考信号和数据收集过程的同步上变化。 或者，可以使用与用于干涉测量的相同光源和光路的高时间相干滤波器。