公开(公告)号：US20140199778A1

公开(公告)日：2014-07-17

申请号：US14239330

申请日：2011-09-30

Applicant: Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

Inventor： Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

IPC: G01N31/22

CPC classification number: G01N31/22 ,  B01L3/5085 ,  B01L3/50853 ,  B01L2200/141 ,  B01L2300/0636 ,  B01L2300/069 ,  B01L2300/0819 ,  B82Y15/00 ,  G01N21/648 ,  G01N21/658 ,  G01N2201/0227 ,  G01N2201/023 ,  Y10T436/25

Abstract: Devices to detect a substance and methods of producing such a device are disclosed. An example device to detect a substance includes a housing defining an externally accessible chamber and a seal to enclose at least a portion of the chamber. The example device also includes a substrate includes nanoparticles positioned within the chamber. The nanoparticles to react to the substance when exposed thereto. The example device also includes a non-analytic solution within the chamber to protect the nanoparticles from premature exposure.

Abstract translation: 公开了检测物质的装置和制造这种装置的方法。 用于检测物质的示例性装置包括限定外部可触及室的壳体和用于封闭室的至少一部分的密封件。 该示例性装置还包括基底，其包括位于腔室内的纳米颗粒。 纳米颗粒暴露于物质时与物质反应。 该示例性装置还包括室内的非分析溶液以保护纳米颗粒免于过早曝光。

公开(公告)号：US08780606B2

公开(公告)日：2014-07-15

申请号：US13120904

申请日：2008-12-23

Applicant: Zhiyong Li ,  Fung Suong Ou ,  William M. Tong

Inventor： Zhiyong Li ,  Fung Suong Ou ,  William M. Tong

IPC: G11C11/00 ,  G11C13/00 ,  B82Y10/00 ,  G11C11/56 ,  G11C13/02 ,  H01L45/00

CPC classification number: G11C13/0011 ,  B82Y10/00 ,  G11C11/56 ,  G11C13/00 ,  G11C13/0002 ,  G11C13/0069 ,  G11C13/02 ,  G11C13/025 ,  G11C2013/009 ,  G11C2213/35 ,  G11C2213/55 ,  G11C2213/56 ,  H01L45/08 ,  H01L45/1206 ,  H01L45/1226 ,  H01L45/1233 ,  H01L45/146

Abstract: A memristive device includes: a first electrode; a second electrode; a memristive matrix interposed between the first electrode and the second electrode; a porous dopant diffusion element in physical contact with the memristive matrix and in proximity to the first electrode and the second electrode; and a first mobile dopant species which moves through the porous dopant diffusion element in response to a programming electrical field. A method for using a memristive device having a porous dopant diffusion element includes applying a voltage bias to generate a programming electrical field such that dopants move through the porous dopant diffusion element, thereby changing the distribution of dopants within a memristive matrix to form a first state; removing the voltage bias, the dopants being substantially immobile in the absence of the programming electrical field; and applying a reading energy to the memristive device to sense the first state.

Abstract translation: 忆阻器包括：第一电极; 第二电极; 夹在第一电极和第二电极之间的忆阻矩阵; 与所述忆阻基体物理接触并且靠近所述第一电极和所述第二电极的多孔掺杂剂扩散元件; 以及响应于编程电场移动穿过多孔掺杂剂扩散元件的第一移动掺杂物种类。 使用具有多孔掺杂剂扩散元件的忆阻器件的方法包括施加电压偏置以产生编程电场，使得掺杂剂移动穿过多孔掺杂剂扩散元件，由此改变在忆阻矩阵内的掺杂剂的分布以形成第一状态 ; 去除电压偏压，掺杂剂在没有编程电场的情况下基本上是不可移动的; 以及向所述忆阻器施加读取能量以感测所述第一状态。

公开(公告)号：US20140125976A1

公开(公告)日：2014-05-08

申请号：US14118801

申请日：2011-05-20

Applicant: Ansoon Kim ,  Zhiyong Li

Inventor： Ansoon Kim ,  Zhiyong Li

IPC: G01N21/65 ,  G01J3/44

CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01J3/44

Abstract: A surface enhanced Raman spectroscopy (SERS) sensor, system and method employ nanorods and independent nanoparticles that interact. The sensor includes at least two spaced apart nanorods attached at first ends to a substrate and an independent nanoparticle. Second ends of the nanorods are movable into close proximity to one another and include a Raman active surface. The nanoparticle has a functionalized surface that includes a Raman signal generator. An interaction between the nanoparticle and the nanorod second ends in close proximity is detectable. The system includes the SERS sensor, an illumination source and a Raman signal detector. The method includes illuminating the interaction of the nanoparticle and the nanorods with an analyte, and detecting an effect on a Raman signal caused by the analyte.

Abstract translation: 表面增强拉曼光谱（SERS）传感器，系统和方法采用纳米棒和独立纳米粒子相互作用。 传感器包括至少两个间隔开的纳米棒，其在第一端附着到基底和独立的纳米颗粒。 纳米棒的第二端可以彼此靠近移动并且包括拉曼活性表面。 纳米颗粒具有包括拉曼信号发生器的官能化表面。 纳米颗粒和纳米棒第二末端之间的相互作用是可以接近的。 该系统包括SERS传感器，照明源和拉曼信号检测器。 该方法包括用分析物照射纳米颗粒和纳米棒的相互作用，并检测由分析物引起的对拉曼信号的影响。

公开(公告)号：US08547549B2

公开(公告)日：2013-10-01

申请号：US13129571

申请日：2008-11-17

Applicant: Huei Pei Kuo ,  Jing Tang ,  Fung Suong Ou ,  Zhiyong Li ,  Shih-Yuan Wang

Inventor： Huei Pei Kuo ,  Jing Tang ,  Fung Suong Ou ,  Zhiyong Li ,  Shih-Yuan Wang

IPC: G01J3/44 ,  G01N21/65

CPC classification number: B82Y20/00 ,  G01N21/658

Abstract: A substrate for Surface Enhanced Raman Scattering (SERS). The substrate comprises at least one nanostructure protruding from a surface of the substrate and a SERS active metal over the at least one nanostructure, wherein the SERS active metal substantially covers the at least one nanostructure and the SERS active metal creates a textured layer on the at least one nanostructure.

Abstract translation: 用于表面增强拉曼散射的衬底（SERS）。 衬底包括从衬底的表面突出的至少一个纳米结构和在至少一个纳米结构上的SERS活性金属，其中SERS活性金属基本上覆盖至少一个纳米结构，并且SERS活性金属在其上形成纹理化层 至少一个纳米结构。

公开(公告)号：US20130217143A1

公开(公告)日：2013-08-22

申请号：US13879255

申请日：2010-10-20

Applicant: Zhiyong Li ,  R. Stanley Williams

Inventor： Zhiyong Li ,  R. Stanley Williams

IPC: G01N21/64

CPC classification number: G01N21/6428 ,  G01N21/648 ,  G01N21/658 ,  G01N33/54373

Abstract: A chemical-analysis device integrated with a metallic-nanofinger device for chemical sensing. The chemical-analysis device includes a metallic-nanofinger device, and a platform. The metallic-nanofinger device includes a substrate, and a plurality of nanofingers coupled with the substrate. A nanofinger of the plurality includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger of the plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule. A morphology of the metallic cap is to generate a shifted plasmonic-resonance peak associated with amplified luminescence from the analyte molecule. A method for using, and a chemical-analysis apparatus including the chemical-analysis device are also provided.

公开(公告)号：US08502198B2

公开(公告)日：2013-08-06

申请号：US11414578

申请日：2006-04-28

Applicant: R. Stanley Williams ,  Zhiyong Li ,  Douglas Ohlberg ,  Philip J. Kuekes ,  Duncan Stewart

Inventor： R. Stanley Williams ,  Zhiyong Li ,  Douglas Ohlberg ,  Philip J. Kuekes ,  Duncan Stewart

IPC: H01L29/08

CPC classification number: G11C13/02 ,  G11C13/0009 ,  G11C2213/77 ,  H01L51/0591

Abstract: A switching device includes at least one bottom electrode and at least one top electrode. The top electrode crosses the bottom electrode at a non-zero angle, thereby forming a junction. A metal oxide layer is established on at least one of the bottom electrode or the top electrode. A molecular layer including a monolayer of organic molecules and a source of water molecules is established in the junction. Upon introduction of a forward bias, the molecular layer facilitates a redox reaction between the electrodes, thereby reducing a tunneling gap between the electrodes.

Abstract translation: 开关装置包括至少一个底部电极和至少一个顶部电极。 顶部电极以非零角度穿过底部电极，从而形成结。 在底电极或顶电极中的至少一个上建立金属氧化物层。 在连接处建立了包括有机分子单层和水分子源的分子层。 在引入正向偏压时，分子层促进电极之间的氧化还原反应，从而减少电极之间的隧道间隙。

公开(公告)号：US20130131000A1

公开(公告)日：2013-05-23

申请号：US13816105

申请日：2011-08-04

Applicant: Chunshan Tang ,  Ning Xie ,  Xiaoling Yang ,  Wuqing Lv ,  Zhiyong Li ,  Jingying Ye ,  Difa Liu ,  Fan Cheng

Inventor： Chunshan Tang ,  Ning Xie ,  Xiaoling Yang ,  Wuqing Lv ,  Zhiyong Li ,  Jingying Ye ,  Difa Liu ,  Fan Cheng

IPC: A61K31/7048

CPC classification number: A61K31/7048 ,  A61K9/00 ,  A61K9/0095 ,  A61K31/352 ,  A61K36/185 ,  A61K45/06 ,  A61K47/18 ,  A61K2236/30 ,  A61K2300/00

Abstract: Disclosed is a composition comprising ligustroflavone, rhoifolin and hyperin, which is prepared according to rational weight ratio: 40% to 80% ligustroflavone, 5% to 45% rhoifolin and 1% to 40% hyperin. The composition can be used as a neuraminidase inhibitor for preventing and treating influenza, and can be formulated into pharmaceutically acceptable dosage forms.

Abstract translation: 公开了一种组合物，其包含根据合理的重量比：40％至80％的连翘黄酮，5％至45％的罗霍林和1％至40％的高辛酸制备的顺黄酮，罗霍林和羟乙酸。 该组合物可以用作预防和治疗流感的神经氨酸酶抑制剂，并且可以配制成药学上可接受的剂型。

公开(公告)号：US20130107250A1

公开(公告)日：2013-05-02

申请号：US13282606

申请日：2011-10-27

Applicant: Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

Inventor： Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

IPC: G01N21/01

CPC classification number: B82Y40/00 ,  B82Y15/00 ,  G01N21/554 ,  G01N21/658

Abstract: A structure for molecular analysis is disclosed. The structure includes a nanostructure and a nanoparticle attached to the nanostructure, wherein the nanostructure is free-standing and wherein the nanoparticle, the nanostructure or both the nanoparticle and the nanostructure are coated with a metal coating; or a plurality of nanoparticles, wherein the plurality of nanoparticles is free-standing and wherein each nanoparticle in the plurality is coated with a metal coating and is separated from one other nanoparticle or two other nanoparticles by a distance of 0.5 nm to 1 nm. A method for preparing the structure for molecular analysis is also disclosed.

Abstract translation: 公开了一种用于分子分析的结构。 该结构包括纳米结构和连接到纳米结构的纳米颗粒，其中纳米结构是独立的，并且其中纳米颗粒，纳米结构或纳米颗粒和纳米结构二者都涂覆有金属涂层; 或多个纳米颗粒，其中所述多个纳米颗粒是独立的，并且其中所述多个纳米颗粒中的每个纳米颗粒涂覆有金属涂层，并且与另外一个纳米颗粒或两个其它纳米颗粒分开0.5nm至1nm的距离。 还公开了用于分子分析结构的制备方法。

公开(公告)号：US20130100436A1

公开(公告)日：2013-04-25

申请号：US13281232

申请日：2011-10-25

Applicant: Warren Jackson ,  Zhiyong Li

Inventor： Warren Jackson ,  Zhiyong Li

IPC: G01N21/01 ,  B29D11/00 ,  B01D35/00 ,  B29C53/04 ,  B01D29/07 ,  C25B7/00

CPC classification number: G01N21/658 ,  B29D11/0074

Abstract: Molecular filters are disclosed herein. An example of the molecular filter includes a rolled substrate having an interior surface and opposed ends that are substantially orthogonal to the interior surface. The rolled substrate defines a layer and a fluid flow path extending from one of the opposed ends to another of the opposed ends. A template is positioned on the interior surface of the rolled substrate. The template includes a matrix, and molecule template locations formed in the matrix.

Abstract translation: 本文公开了分子过滤器。 分子过滤器的一个实例包括具有内表面和基本上正交于内表面的相对端的轧制衬底。 卷绕的基板限定了从相对端中的一个延伸到相对端中的另一个的层和流体流动路径。 模板位于轧制衬底的内表面上。 模板包括在矩阵中形成的矩阵和分子模板位置。

公开(公告)号：US08390444B2

公开(公告)日：2013-03-05

申请号：US12770941

申请日：2010-04-30

Applicant: Zhiyong Li ,  Peter G. Hartwell

Inventor： Zhiyong Li ,  Peter G. Hartwell

IPC: G08B1/08

CPC classification number: G01S1/68 ,  G01S1/70

Abstract: A sensor-location system for locating sensors in a tract covered by an earth-based sensor network. The sensor-location system includes at least one sensor-identification device, and at least one sensor locator. The sensor-identification device is affixed to a respective sensor in the earth-based sensor network. The sensor locator is configured for use from on board of an aircraft. In addition, the sensor locator is configured to acquire geographic-location data of said sensor including an identifying signature from the sensor-identification device of the sensor in the tract covered by the earth-based sensor network.

Abstract translation: 传感器定位系统，用于将传感器定位在由地球传感器网络覆盖的道路中。 传感器定位系统包括至少一个传感器识别装置和至少一个传感器定位器。 传感器识别装置固定到基于地球的传感器网络中的相应传感器。 传感器定位器配置为可从飞机上使用。 此外，传感器定位器被配置为从由地球传感器网络覆盖的道路中获取来自传感器的传感器识别装置的识别签名的所述传感器的地理位置数据。