Device for reconstituting a drug vial and transferring the contents to a syringe in an automated matter
    261.
    发明申请
    Device for reconstituting a drug vial and transferring the contents to a syringe in an automated matter 有权
    用于重组药瓶并将内容物转移到自动化物质中的注射器的装置

    公开(公告)号:US20050224137A1

    公开(公告)日:2005-10-13

    申请号:US10821268

    申请日:2004-04-07

    CPC classification number: A61J1/20 A61J1/201 A61J1/2055 A61J1/2096 B65B3/003

    Abstract: In one exemplary embodiment, an automated medication preparation system is provided and is in the form of an automated syringe preparation that includes reconstitution of the medication and delivery of the reconstituted medication to a syringe. The system includes an automated fluid delivery device that is movable in at least one direction and is adapted to perform at least one of the following operations: (1) receiving and discharging diluent from a diluent supply in a prescribed amount to reconstitute the medication in a drug vial; and (2) aspirating and later discharging reconstituted medication from the drug vial into the syringe. The system also includes a transfer device that includes a first section for piercing the septum of the drug vial and a second section for sealingly yet releasably mating with the fluid delivery device. The transfer device is constructed so that it remains within the drug vial for multiple uses without the need to pierce the septum more than one time and therefore, the disadvantages associated with the prior art are overcome. The transfer device has a first channel extending through the first and second sections for carrying diluent or reconstituted medication and a second channel that is in fluid communication with a vent that is formed as part of the transfer device to permit air to flow into the drug vial.

    Abstract translation: 在一个示例性实施方案中,提供自动化药物制备系统并且是自动注射器制剂的形式,其包括重新配制药物和将重组药物递送至注射器。 该系统包括自动化的流体输送装置,其可在至少一个方向上移动并且适于执行以下操作中的至少一个:(1)从稀释剂供应源中以规定的量接收和排出稀释剂以重新构成药物 药瓶; 和(2)将药物小瓶中的重新配制的药物抽吸并稍后排出到注射器中。 该系统还包括转移装置,其包括用于刺穿药物瓶的隔膜的第一部分和用于密封地可释放地与流体输送装置配合的第二部分。 转移装置被构造成使得其保持在药物瓶内用于多次使用,而不需要多次刺穿隔膜,因此克服了与现有技术相关的缺点。 传送装置具有延伸穿过第一和第二部分的第一通道,用于承载稀释剂或复原药物,以及第二通道,其与形成为转运装置一部分的通气口流体连通,以允许空气流入药物瓶 。

    Needle-free single-use cartridge and injection system
    263.
    发明申请
    Needle-free single-use cartridge and injection system 审中-公开
    无针式一次性墨盒和注射系统

    公开(公告)号:US20050209554A1

    公开(公告)日:2005-09-22

    申请号:US10861891

    申请日:2004-06-04

    Applicant: Sergio Landau

    Inventor: Sergio Landau

    CPC classification number: A61M5/30 A61J1/201 A61J1/2096 A61M5/1782

    Abstract: A needle-free injection system, including an injection device and a vial adapter. The injection device is configured to be loaded with a dose of injectable fluid and forcibly inject such dose into an injection site. The vial adapter is configured to secure to and selectively seal a vial containing an external supply of injectable fluid. The vial adapter also includes a flexible adapter structure biased into a blocking position. The injection device includes a filling adapter configured to move the flexible adapter structure out of the blocking position to thereby permit the vial adapter and injection device to be secured together in an engaged configuration. In this engaged configuration, a dose of injectable fluid may be drawn from the external supply of injectable fluid into the injection device.

    Abstract translation: 无针注射系统,包括注射装置和小瓶适配器。 注射装置被配置为装载一定剂量的可注射流体,并将这种剂量强制地注入注射部位。 小瓶适配器被配置为固定并选择性地密封容纳有可注射流体的外部供应的小瓶。 小瓶适配器还包括偏置到阻挡位置的柔性适配器结构。 注射装置包括填充适配器,其配置成将柔性适配器结构移动离开阻塞位置,从而允许小瓶适配器和注射装置以接合构型固定在一起。 在该接合构造中,可注射流体的剂量可以从外部可注射流体供应到注射装置中。

    Fluid transfer holder assembly and a method of fluid transfer
    265.
    发明申请
    Fluid transfer holder assembly and a method of fluid transfer 有权
    流体转移支架组件和流体转移方法

    公开(公告)号:US20050148992A1

    公开(公告)日:2005-07-07

    申请号:US10749514

    申请日:2004-01-02

    Abstract: A fluid transfer system has a holder that is made of a cylindrical member having a closed end and an open end. The closed end has fitted thereto a luer and a cannula that extends into the interior of the holder. The holder has a distal portion that has a first cross section and a proximal portion that has a second cross section. The cross section of the distal portion is smaller than the cross section of the proximal portion. The distal and proximal portions are joined by a shoulder. The fluid transfer system also includes an adapter that is inserted to the holder from the open end of the holder. The adapter has a base having a central opening and a cylindrical tube that extends from the central opening. The diameter of the cylindrical tube is slightly smaller than the diameter of the distal portion and is configured to accept a first type of fluid collection store such as a vacuum tube. A non-continuous wall extends from the base of the adapter to surround the cylindrical tube. The cross section of the wall is slightly smaller than the diameter of the proximal portion. At each section of the non-continuous wall there is formed a protuberance. A groove is formed about the inner surface of the proximal portion. When the adapter is fully inserted to the holder, the protuberances would snap fit to the groove so that the adapter is prevented from being inadvertently removed from the holder. With the adapter removed, the holder can accept a differently dimensioned fluid collection store such as for example a blood culture collection bottle.

    Abstract translation: 流体输送系统具有由具有封闭端和开口端的圆柱形构件制成的保持器。 封闭的端部装配有延伸到保持器内部的路厄尔和套管。 保持器具有具有第一横截面的远端部分和具有第二横截面的近端部分。 远侧部分的横截面小于近端部分的横截面。 远端和近端部分由肩部连接。 流体输送系统还包括从保持器的开口端插入到保持器中的适配器。 适配器具有具有中心开口的基部和从中心开口延伸的圆柱形管。 圆柱形管的直径略小于远端部分的直径,并且构造成接受第一类型的流体收集储存器,例如真空管。 不连续的壁从适配器的底部延伸以围绕圆柱形管。 壁的横截面略小于近端部分的直径。 在非连续墙的每个部分形成一个突起。 围绕近端部分的内表面形成凹槽。 当适配器完全插入保持器时,突起将卡扣配合到凹槽,使得防止适配器被无意地从保持器移除。 随着适配器被移除,保持器可以接受不同尺寸的流体收集储存器,例如血液培养收集瓶。

    Tool for use with a medication vial and/or a syringe
    266.
    发明申请
    Tool for use with a medication vial and/or a syringe 有权
    用于药物瓶和/或注射器的工具

    公开(公告)号:US20050056121A1

    公开(公告)日:2005-03-17

    申请号:US10910064

    申请日:2004-08-03

    Applicant: Scott Lyman

    Inventor: Scott Lyman

    Abstract: A tool for use with a medication vial and a syringe comprises a housing having a top side, a bottom side, and a surrounding edge, a slotted aperture defined in the housing and including a flange shaped to engage vial cap, a cylindrical aperture defined in the housing and sized to permit placement of a forward portion of the syringe including a cap into the cylindrical aperture, an actuator button mounted to the housing, and a gripper mounted within the housing and having a pair of opposed edges, with the gripper responsive to movement of the actuator button to permit movement of the edges between a retracted position in which the edges are disposed away from a central portion of the cylindrical aperture, and an extended position in which the edges are displaced toward the central portion of the cylindrical aperture.

    Abstract translation: 用于药物瓶和注射器的工具包括具有顶侧,底侧和周围边缘的壳体,限定在壳体中的开槽孔,并且包括成形为接合小瓶盖的凸缘, 壳体并且尺寸适于允许将包括盖的注射器的前部部分放置到圆柱形孔中,安装到壳体的致动器按钮以及安装在壳体内并具有一对相对边缘的夹持器,夹具响应于 致动器按钮的移动以允许边缘在其中边缘被设置为远离圆柱形孔的中心部分的缩回位置之间移动,并且其中边缘朝向圆柱形孔的中心部分移位的延伸位置。

    Blow fill sealed container with twist off top operated by overcap and method of forming the same
    267.
    发明申请
    Blow fill sealed container with twist off top operated by overcap and method of forming the same 失效
    吹瓶盖密封容器,顶盖操作,顶盖操作方法

    公开(公告)号:US20050051572A1

    公开(公告)日:2005-03-10

    申请号:US10655718

    申请日:2003-09-05

    Abstract: A container assembly includes a container body having a port or aperture adapted for use with a luer end of a needleless syringe. The aperture is sealed to a closure top by a first frangible seal. An overcap has a cap base sealed to the container body and an upper cap connected to the cap base by a second frangible seal, providing a sterile barrier surrounding the first frangible seal. The second frangible seal is broken by depressing the upper cap toward the container body. Alternatively, the second frangible seal is a removable tear strip broken by tugging on the tear strip. The upper cap includes a detent portion frictionally securing the upper cap to the closure top when the upper cap is depressed toward the container body. The upper cap and secured closure top are removed from container body by twisting the upper cap to break the first frangible seal and open the port.

    Abstract translation: 容器组件包括具有适于与无针注射器的鲁尔端一起使用的端口或孔的容器体。 孔通过第一个易碎密封件密封到封闭顶部。 盖子具有密封到容器主体的盖基部和通过第二易碎密封件连接到盖基部的上盖,提供围绕第一易碎密封件的无菌屏障。 通过将上盖朝向容器主体压下来破坏第二个易碎的密封。 或者,第二易碎密封件是通过在撕裂带上拉动而破裂的可拆卸撕裂条。 上盖包括当上盖朝向容器主体压下时将上盖摩擦地固定到封闭顶部的止动部分。 上盖和固定的封闭顶部通过扭转上盖而从容器主体中取出,以破坏第一易碎密封并打开端口。

    Sliding reconstitution device with seal
    268.
    发明授权
    Sliding reconstitution device with seal 有权
    带密封的滑动重构装置

    公开(公告)号:US06852103B2

    公开(公告)日:2005-02-08

    申请号:US10346902

    申请日:2003-01-16

    Abstract: The present invention provides a connector device for establishing fluid communication between a first container and a second container. The device has a first sleeve member having a first and a second end, the first sleeve member having at the first end a first attaching member adapted to attach to the first container. The device further has a second sleeve member having a first end and a second end, the second sleeve member being associated with the first sleeve member and movable with respect thereto from an inactivated position to an activated position, the second sleeve member having at the second end a second attaching member adapted to attach the second sleeve member to the second container. First and second piercing members project from one of the first and second sleeve members for providing a fluid flow path from the first container to the second container, and the first and second piercing members are independently hermetically sealed.

    Abstract translation: 本发明提供一种用于在第一容器和第二容器之间建立流体连通的连接器装置。 该装置具有第一和第二端部的第一套筒构件,第一套筒构件在第一端具有适于附接到第一容器的第一附接构件。 所述装置还具有第二套筒构件,所述第二套筒构件具有第一端和第二端,所述第二套筒构件与所述第一套筒构件相关联并且可相对于所述第一套筒构件从非活动位置移动到致动位置,所述第二套筒构件具有第二套筒构件 结束适于将第二套筒构件附接到第二容器的第二附接构件。 第一和第二穿刺构件从第一和第二套筒构件之一突出,用于提供从第一容器到第二容器的流体流动路径,并且第一和第二穿孔构件被独立地密封。

    System and method for mixing at least four components
    269.
    发明申请
    System and method for mixing at least four components 有权
    用于混合至少四种组分的系统和方法

    公开(公告)号:US20050027240A1

    公开(公告)日:2005-02-03

    申请号:US10890149

    申请日:2004-07-14

    Abstract: A system for mixing four components (K1, K2, K3, K4) has a first syringe arrangement (10) and a second syringe arrangement (20). The first and second syringe arrangements (10, 20) each contain at least two chambers (11, 12; 21, 22) for holding one each of the components (K1, K2, K3, K4). It is possible to connect each chamber of one of the syringe arrangements (10) in a detachable fashion to a chamber (21, 22) of the other syringe arrangement (20). By transferring the components (K1, K2) from one of the syringe arrangements (10) into chambers (21, 22) of the other syringe arrangement (20), the transferred components (K1, K2) are mixed with components (K3, K4) which are contained in this chamber (21, 22).

    Abstract translation: 用于混合四个部件(K1,K2,K3,K4)的系统具有第一注射器装置(10)和第二注射器装置(20)。 第一和第二注射器装置(10,20)各自包含用于保持组件(K1,K2,K3,K4)中的每一个的至少两个腔室(11,12; 21,22)。 可以将一个注射器装置(10)的每个腔室以可拆卸的方式连接到另一注射器装置(20)的腔室(21,22)。 通过将组件(K1,K2)从其中一个注射器装置(10)转移到另一个注射器装置(20)的腔室(21,22)中,将转移的组分(K1,K2)与组分(K3,K4) ),其被包含在该室(21,22)中。

    Hazardous material handling system and method
    270.
    发明申请
    Hazardous material handling system and method 审中-公开
    危险物料处理系统和方法

    公开(公告)号:US20040249235A1

    公开(公告)日:2004-12-09

    申请号:US10453393

    申请日:2003-06-03

    Abstract: A method and system for handling hazardous materials contained in a vial includes an isolation enclosure having an opening selectively sealable about the vial, a bag body portion, and a cap portion. A latching extraction element is attached to the cap portion and has a preceding engaging member to secure the vial to the isolation enclosure, an extraction member to be inserted into the vial and remove material therefrom, and a primary engaging member to secure the vial to the extraction member. A valve is mounted outside the isolation enclosure and controls the flow of fluid from the vial. An adaptor having a reseal member permits flow when coupled to the valve and restricts flow when uncoupled from the valve. Once uncoupled, the adaptor is removably associated with a second valve located remotely from the isolation enclosure, allowing fluid to pass into the second valve.

    Abstract translation: 用于处理容纳在小瓶中的有害物质的方法和系统包括隔离罩,其具有可围绕小瓶选择性密封的开口,袋体部分和帽部分。 闩锁提取元件附接到盖部分并且具有先前的接合构件以将小瓶固定到隔离外壳,提取构件被插入到小瓶中并从中移除材料,以及主接合构件以将小瓶固定到 提取成员。 阀门安装在隔离罩外部,并控制流体从瓶中流出。 具有重新密封构件的适配器在连接到阀时允许流动,并且当与阀脱离时限制流动。 一旦脱开,适配器可拆卸地与位于远离隔离外壳的第二阀相关联,允许流体进入第二阀。

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