Tissue dissociating system and method
    21.
    发明授权
    Tissue dissociating system and method 失效
    组织解离系统及方法

    公开(公告)号:US5786207A

    公开(公告)日:1998-07-28

    申请号:US864444

    申请日:1997-05-28

    IPC分类号: C12M3/08 C07G17/00

    CPC分类号: C12M45/02 C12M45/05 C12M47/04

    摘要: A tissue dissociation method and system for washing and dissociating tissue and producing a cellular suspension for use in autologous, cell-based therapies or research wherein a sterile environment is maintained. More particularly, a system for dissociating tissue comprising a housing unit, a first compartment having a plurality of pores providing for fluid communication between the interior of the first compartment and the interior of the housing unit, a first inlet port that provides communication between the exterior environment and the interior of the first compartment and thereby provides a means for introducing solutions into the interior of the first compartment, a second compartment, a second inlet port for introducing a tissue sample into the system, a means for agitating or rotating the second compartment in the housing unit, a means for controlling the exit of effluent from the housing unit, a first receptacle, and a centrifuge-ready second receptacle for collecting a resulting cell suspension. The method comprises introducing a tissue sample into the system and subjecting it to a washing phase and a dissociating phase wherein the tissue is agitated or rotated. The tissue may also be subjected to a sedentary phase and a phase in which a solution is added to the resulting cell suspension to cease tissue dissociation. At the conclusion of the tissue dissociation process, the resulting cell suspension is collected in a centrifuge-ready receptacle.

    摘要翻译: 用于洗涤和解离组织并产生用于自体,基于细胞的疗法或研究中的细胞悬浮液的组织解离方法和系统,其中维持无菌环境。 更具体地,涉及用于解离组织的系统,包括壳体单元,具有提供用于在第一隔室的内部和壳体单元的内部之间流体连通的多个孔的第一隔室,提供外部之间的连通的第一入口端口 环境和第一隔室的内部,从而提供用于将溶液引入第一隔室的内部的装置,第二隔室,用于将组织样品引入系统的第二入口端口,用于搅动或旋转第二隔室 在壳体单元中,用于控制来自壳体单元的流出物的排出的装置,第一容器和用于收集所得到的细胞悬浮液的离心机就绪的第二容器。 该方法包括将组织样品引入系统并使其经历洗涤阶段和解离阶段,其中组织被搅动或旋转。 组织也可以经受静止期和将所述溶液加入到所得细胞悬浮液中以停止组织解离的阶段。 在组织解离过程结束时,将得到的细胞悬浮液收集在离心机容器中。

    Arm supported drinking container
    22.
    发明授权
    Arm supported drinking container 失效
    扶手式饮水容器

    公开(公告)号:US5566869A

    公开(公告)日:1996-10-22

    申请号:US494326

    申请日:1995-06-26

    申请人: Adam J. Katz

    发明人: Adam J. Katz

    IPC分类号: A45F3/16 A45F5/00 F16K15/04

    摘要: A container for supporting a quantity of fluid relative to a limb of an individual. The inventive device includes a container having an arcuate inner side wall positionable along an exterior of a human limb. A plurality of securing straps extend from opposed sides of the container for securing about the limb to mount the container thereto. A dispensing valve is mounted relative to the container to permit dispensing of fluid therefrom during a physical activity.

    摘要翻译: 用于支撑相对于个人肢体的流体的容器。 本发明的装置包括具有可沿人肢的外部定位的弓形内侧壁的容器。 多个固定带从容器的相对侧延伸,用于围绕肢体固定以将容器安装到其上。 分配阀相对于容器安装以允许在身体活动期间从其中分配流体。