公开(公告)号：US11994460B2

公开(公告)日：2024-05-28

申请号：US17545620

申请日：2021-12-08

Applicant: Sorin Group Italia S.r.l.

Inventor： Andrea Galavotti ,  Gabriele Tommasi ,  Giampaolo Simonini ,  Marco Luppi ,  Andrea Zaniboni ,  Paola Capriati

IPC: G01N21/03 ,  A61B5/1455 ,  G01N21/64 ,  A61B5/15

CPC classification number: G01N21/0303 ,  A61B5/14557 ,  G01N21/645 ,  A61B5/150992 ,  G01N2021/0367 ,  G01N2021/6432 ,  G01N2021/6482

Abstract: A system includes a cuvette including a cuvette body forming a substantially planar exterior surface and having a sensor window defined within the substantially planar exterior surface. The cuvette further includes a probe retention structure extending from the cuvette body. The system includes a probe with a probe body and a protrusion that is removably coupled to the probe retention structure.

公开(公告)号：US20240130358A1

公开(公告)日：2024-04-25

申请号：US18403061

申请日：2024-01-03

Applicant: SORIN GROUP ITALIA S.R.L. ,  SORBONNE UNIVERSITE ,  INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE ,  ASSISTNCE PUBLIQUE- HOPTAUX DE PARIS

Inventor： John F. Migliazza ,  Sandra Spiritelli ,  Olivier Scatton ,  Eric Savier ,  Claire Goumard

IPC: A01N1/02

CPC classification number: A01N1/0247 ,  A01N1/021 ,  A01N1/0284

Abstract: An organ perfusion and preservation system for use in preserving an organ from a donor, may include a fluid reservoir, a heat exchanger in fluid communication with the fluid reservoir and configured to selectively raise and lower a temperature of a perfusion fluid, an oxygenator configured to oxygenate the perfusion fluid, an inflow pump in fluid communication with the fluid reservoir and the oxygenator, a fluid inflow line configured to transport perfusion fluid from the oxygenator to the organ, a fluid outflow line configured to transport perfusion fluid away from the organ and back to the reservoir, an outflow pump in fluid communication with the fluid outflow line and the fluid reservoir, and a controller operatively connected to the inflow pump, the outflow pump, and the heat exchanger, wherein the controller is configured to select parameters to reversibly heat and reversibly cool the organ.

公开(公告)号：US20230052266A1

公开(公告)日：2023-02-16

申请号：US17950495

申请日：2022-09-22

Applicant: Sorin Group Italia S.r.l.

Inventor： Clara Pandolfini ,  Francesco Benatti ,  Claudio Silvestri

IPC: A61M1/36

Abstract: An apparatus includes a blood-flow-management assembly shaped to define a cylindrical aperture. The blood-flow-management assembly includes a blood collector having drainage holes configured to direct blood to a guide surface positioned below the blood collector. The guide surface may further include ribs that manage blood flow along the guide surface.

公开(公告)号：US11471577B2

公开(公告)日：2022-10-18

申请号：US16439019

申请日：2019-06-12

Applicant: Sorin Group Italia S.r.l.

Inventor： Stefano Reggiano

IPC: A61M1/16 ,  B01D63/10

Abstract: A blood processing apparatus includes an optional heat exchanger and a gas exchanger disposed within a housing. In some instances, the gas exchanger can include a screen filter spirally wound into the gas exchanger such that blood passing through the gas exchanger passes through the screen filter and is filtered by the spirally wound screen filter a plurality of times.

公开(公告)号：US10709637B2

公开(公告)日：2020-07-14

申请号：US15529933

申请日：2014-11-26

Applicant: Sorin Group Italia S.r.l.

Inventor： Stefano Spro ,  Stefano Reggiani ,  Claudio Silvestri ,  Francesco Benatti ,  Adriano Mazzoli

IPC: A61J1/10 ,  A61J1/14 ,  A61M1/36 ,  A61M39/10 ,  A61M39/28 ,  A61M5/14

Abstract: A venous reservoir including a single inlet line clamp capable of partially or completely restricting blood flow to the venous reservoir. The venous reservoir is provided with a rigid back plate or bracket that can accommodate an inlet line capable of joining to at least one blood inlet port. The rigid back plate or bracket can accommodate a clamp capable of completely or partially closing the inlet line containing both the cardiotomy line and the venous line to manually control the blood flow drained from the patient.

公开(公告)号：US20190143074A1

公开(公告)日：2019-05-16

申请号：US16242779

申请日：2019-01-08

Applicant: Sorin Group Italia S.r.l.

Inventor： Randall Moshinsky ,  James McMillan ,  Elli Tutungi

IPC: A61M25/00 ,  A61M1/36

Abstract: A bi-directional perfusion cannula is provided that includes an elongate tube for insertion into an artery. The elongate tube has a first aperture at a distal end of the tube which is forward during insertion and configured so that blood can flow into the artery in the direction of insertion, an elbow formed in the elongate tube, and a second aperture formed in or slightly rearward of the elbow and configured for supplying blood into the artery in a second direction which is generally opposite to the insertion direction.

公开(公告)号：US20190104986A1

公开(公告)日：2019-04-11

申请号：US16211444

申请日：2018-12-06

Applicant: Sorin Group Italia S.r.l.

Inventor： Marco Ranucci

IPC: A61B5/00 ,  A61B5/0205 ,  A61M1/36 ,  A61B5/145 ,  A61M1/32 ,  A61B5/01 ,  A61M1/14 ,  G16H40/63 ,  A61B5/08

Abstract: A monitoring system for cardiac operations with cardiopulmonary bypass comprising: a processor operatively connected to a heart-lung machine; a pump flow detecting device connected to a pump of the heart-lung machine to continuously measure the pump flow value and send it to the processor; a hematocrit reading device inserted inside the arterial or venous line of the heart-lung machine to continuously measure the blood hematocrit value and to send it to the processor; a data input device to allow the operator to manually input data regarding the arterial oxygen saturation and the arterial oxygen tension; computing means integrated in the processor to compute the oxygen delivery value on the basis of the measured pump flow, the measured hematocrit value, the preset value of arterial oxygen saturation, and the preset value of arterial oxygen tension; and a display connected to the processor to display in real-time the computed oxygen delivery value.

公开(公告)号：US09867695B2

公开(公告)日：2018-01-16

申请号：US13963191

申请日：2013-08-09

Applicant: Sorin Group Italia S.r.l.

Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2250/0039

Abstract: A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.

公开(公告)号：US09402943B2

公开(公告)日：2016-08-02

申请号：US14156937

申请日：2014-01-16

Applicant: Sorin Group Italia S.r.l. ,  Politecnico di Milano

Inventor： Stefano Reggiani ,  Gianfranco Beniamino Fiore ,  Alberto Redaelli ,  Christian Baiotto

IPC: A61M1/16 ,  A61M1/32 ,  B01D63/02 ,  F28D7/10 ,  F28D7/16 ,  F28F21/06 ,  A61M1/36 ,  F28D21/00

CPC classification number: A61M1/1698 ,  A61M1/32 ,  A61M1/3627 ,  A61M1/3666 ,  A61M1/3667 ,  A61M2206/10 ,  A61M2206/14 ,  A61M2206/16 ,  A61M2206/18 ,  A61M2206/20 ,  B01D63/02 ,  B01D2313/08 ,  B01D2313/19 ,  B01D2313/32 ,  B01D2313/38 ,  F28D7/103 ,  F28D7/1623 ,  F28D21/0015 ,  F28D2021/005 ,  F28F13/06 ,  F28F21/06 ,  F28F21/062 ,  F28F2260/00 ,  Y10S128/03 ,  Y10S261/28

Abstract: A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.

Abstract translation: 血液处理装置可以包括热交换器和气体交换器。 热交换器和气体交换器中的至少一个可以被配置成赋予径向分量以吹动通过热交换器和/或气体交换器。 热交换器可以被配置为使血液流动遵循螺旋流动路径。

公开(公告)号：US20160193044A1

公开(公告)日：2016-07-07

申请号：US14910975

申请日：2014-07-17

Applicant: SORIN GROUP ITALIA S.R.L.

Inventor： Monica A. ACHILUZZI

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2436 ,  A61F2/2457 ,  A61F2220/0033 ,  A61F2230/0069 ,  A61F2250/006

Abstract: A heart valve prosthesis configured to be implanted at cardiac valve annulus located at an interface between a ventricle (LV) and an atrium (LA), the heart valve prosthesis including: a first portion configured for enclosing a plurality of chordae tendineae (CT) in the ventricle (LV) and native valve leaflets (NVL) to which said chordae tendineae are connected, and a second portion including a radially expandable annular member and a prosthetic heart valve anchored to said radially expandable annular member, wherein said first portion is configured to be implanted in the ventricle (LV), and wherein said second portion is configured to be implanted and coupled to the first portion at the cardiac valve annulus.

Abstract translation: 一种心脏瓣膜假体，其构造成植入位于心室（LV）和心房（LA）之间的界面处的心脏瓣膜环处，所述心脏瓣膜假体包括：第一部分，其构造成用于将多个腱索（CT）包围在 所述腱索连接到的心室（LV）和天然瓣叶（NVL），以及第二部分，其包括锚定到所述可径向扩张的环形构件的可径向扩张的环形构件和假体心脏瓣膜，其中所述第一部分被配置为 植入心室（LV）中，并且其中所述第二部分构造成在心脏瓣膜环处植入和联接到第一部分。