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62 条记录 (耗时 0.021 秒)

    Cell lysis by heating-cooling process through endothermic reaction
    21.
    发明授权
    Cell lysis by heating-cooling process through endothermic reaction 有权
    通过吸热反应通过加热 - 冷却过程进行细胞裂解

    公开(公告)号：US07521246B2

    公开(公告)日：2009-04-21

    申请号：US11335414

    申请日：2006-01-19

    申请人： Ji-yeon Yang ,  Yoon-kyoung Cho ,  Jin-tae Kim ,  Sook-young Kim ,  Young-sun Lee

    发明人： Ji-yeon Yang ,  Yoon-kyoung Cho ,  Jin-tae Kim ,  Sook-young Kim ,  Young-sun Lee

    IPC分类号： G01N33/48

    CPC分类号： C12N1/066 ,  C12M47/06 ,  C12M47/20 ,  Y10T436/25

    摘要： Provided is a cell lysis method including: preparing a cell sample to be lysed; heating the cell sample; and cooling the cell sample by causing an endothermic reaction near the cell sample. According to the method, cell lysis can be simply and conveniently performed without regard to location and without additional devices since a separate energy source is not required and the apparatus is portable. In particular, when cell lysis is performed in a biochip using a small amount of sample, a greater cell lysis effect can be obtained. In addition, cell lysis efficiency is significantly improved, compared to when only heating is performed.

    摘要翻译： 提供了一种细胞裂解方法，包括：制备待裂解的细胞样品; 加热细胞样品; 并通过在细胞样品附近引起吸热反应来冷却细胞样品。 根据该方法，可以简单且方便地进行细胞裂解，而不考虑位置和不需要额外的装置，因为不需要单独的能源并且该装置是便携式的。 特别是，在使用少量样品的生物芯片中进行细胞裂解时，可以获得更大的细胞裂解效果。 此外，与仅进行加热时相比，细胞裂解效率显着提高。

    METHOD OF REDUCING TEMPERATURE DIFFERENCE BETWEEN A PAIR OF SUBSTRATES AND FLUID REACTION DEVICE USING THE SAME
    23.
    发明申请
    METHOD OF REDUCING TEMPERATURE DIFFERENCE BETWEEN A PAIR OF SUBSTRATES AND FLUID REACTION DEVICE USING THE SAME 有权
    降低基板对流与使用其的流体反应装置之间的温度差异的方法

    公开(公告)号：US20080053647A1

    公开(公告)日：2008-03-06

    申请号：US11689640

    申请日：2007-03-22

    申请人： Kak Namkoong ,  Su-hyeon Kim ,  Jin-tae Kim ,  Chin-sung Park ,  Young-sun Lee

    发明人： Kak Namkoong ,  Su-hyeon Kim ,  Jin-tae Kim ,  Chin-sung Park ,  Young-sun Lee

    IPC分类号： F28F7/00

    CPC分类号： B81B3/0081 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00873 ,  B01L3/5027 ,  B01L7/5255 ,  B01L2200/14 ,  B01L2200/147 ,  B01L2300/1805 ,  B01L2300/1827 ,  B81B2201/051 ,  F28F21/02 ,  F28F2013/006

    摘要： A method of reducing a temperature difference between a high-temperature and a low-temperature substrate includes interposing a heat transfer facilitating layer which has a higher thermal conductivity than air and can hold particles between the substrates, and maintaining close contact between the high-temperature substrate, the heat transfer facilitating layer, and the low-temperature substrate, wherein formation of an air layer can be at least substantially prevented between the high-temperature substrate and the heat transfer facilitating layer, and between the low-temperature substrate and the heat transfer facilitating layer. A fluid reaction device includes a microfluidic reaction chip which accommodates a fluid, a heater, and a heat transfer facilitating layer which is interposed between the microfluidic reaction chip and the heater, the heat transfer facilitating layer has a higher thermal conductivity than air and can hold particles, wherein formation of an air layer can be prevented.

    摘要翻译： 降低高温和低温基板之间的温度差的方法包括：介于热传导率高于空气的传热促进层，并且可以在基板之间保持颗粒，并且保持高温 基板，传热促进层和低温基板，其中至少可以在高温基板和传热促进层之间以及在低温基板和热量之间基本上防止空气层的形成 转移促进层。 流体反应装置包括容纳流体的微流体反应芯片，加热器和介于微流体反应芯片和加热器之间的传热促进层，传热促进层具有比空气更高的导热性并且可以保持 颗粒，其中可以防止空气层的形成。

    Temperature control method and apparatus for driving polymerase chain reaction (PCR) chip
    25.
    发明授权
    Temperature control method and apparatus for driving polymerase chain reaction (PCR) chip 有权
    用于驱动聚合酶链反应（PCR）芯片的温度控制方法和装置

    公开(公告)号：US07060948B2

    公开(公告)日：2006-06-13

    申请号：US10307694

    申请日：2002-12-02

    申请人： Dong-il Cho ,  Dae-sung Yoon ,  Young-sun Lee ,  Dong-hoon Yi ,  Geun-bae Lim

    发明人： Dong-il Cho ,  Dae-sung Yoon ,  Young-sun Lee ,  Dong-hoon Yi ,  Geun-bae Lim

    IPC分类号： H05B1/02

    CPC分类号： B01L7/525 ,  B01L2200/147 ,  G05D23/1934 ,  Y10T307/469

    摘要： Provided are a temperature control method and apparatus for driving a polymerize chain reaction (PCR) chip. In the temperature control apparatus, which is for a polymerize chain reaction chip, PCR chips receive electric power from the outside and generating heat to maintain a predetermined temperature and for outputting actual temperature information to the outside. electric power supply units supply electric power to the PCR chips according to input control signals, and a controller generates the control signals based on control information including pre-established control temperature and control time information and the actual temperature information supplied from the PCR chips in order to supply the control signals to the electric power supply units. In the present invention, it is possible to examine various kinds of DNA at the same time because the temperature control apparatus controls the temperatures of DNA samples at the same time.

    摘要翻译： 提供了用于驱动聚合链式反应（PCR）芯片的温度控制方法和装置。 在用于聚合链式反应芯片的温度控制装置中，PCR芯片从外部接收电力并产生热量以保持预定温度并将实际温度信息输出到外部。 电源单元根据输入控制信号向PCR芯片提供电力，并且控制器基于包括预先建立的控制温度和控制时间信息的控制信息以及从PCR芯片提供的实际温度信息按顺序产生控制信号 以将控制信号提供给电力供应单元。 在本发明中，可以同时检测各种DNA，因为温度控制装置同时控制DNA样品的温度。

    MOBILE TERMINAL CAPABLE OF RECOGNIZING FINGERNAIL TOUCH AND METHOD OF CONTROLLING THE OPERATION THEREOF
    28.
    发明申请
    MOBILE TERMINAL CAPABLE OF RECOGNIZING FINGERNAIL TOUCH AND METHOD OF CONTROLLING THE OPERATION THEREOF 有权
    识别手指触摸的移动终端和控制其操作的方法

    公开(公告)号：US20100279738A1

    公开(公告)日：2010-11-04

    申请号：US12769422

    申请日：2010-04-28

    申请人： Jong Hwan KIM ,  Seung Hwan YOO ,  Doo Hwan KIM ,  Mi Jung KIM ,  Soo Chul LIM ,  Young Sun LEE ,  Eun Sang LEE

    发明人： Jong Hwan KIM ,  Seung Hwan YOO ,  Doo Hwan KIM ,  Mi Jung KIM ,  Soo Chul LIM ,  Young Sun LEE ,  Eun Sang LEE

    IPC分类号： H04W88/02 ,  G06F3/041

    CPC分类号： G06F3/041 ,  G06F3/016 ,  G06F3/0428 ,  G06F3/0488 ,  G06F2203/04106

    摘要： A method of controlling a mobile terminal, and which includes displaying, on a touch screen display of the mobile terminal, an operation screen corresponding to a current operating mode executing on the mobile terminal; detecting, via a detecting device, a touch input on the touch screen display of the mobile terminal; determining, via a controller on the mobile terminal, a first finger characteristic describing a finger touching the touch screen display and a second finger characteristic describing the finger touching the touch screen display that is different than the first finger characteristic; performing, via the controller, a first operation relevant to the current operating mode based on the determined first finger characteristic; and performing, via the controller, a second operation relevant to the current operating mode based on the determined second finger characteristic.

    摘要翻译： 一种控制移动终端的方法，包括在移动终端的触摸屏显示器上显示与在移动终端上执行的当前操作模式相对应的操作画面; 经由检测装置检测所述移动终端的触摸屏显示器上的触摸输入; 通过所述移动终端上的控制器确定描述触摸所述触摸屏显示的手指的第一手指特征和描述所述手指触摸所述触摸屏显示不同于所述第一手指特征的第二手指特征; 基于所确定的第一手指特征，经由所述控制器执行与所述当前操作模式相关的第一操作; 以及基于所确定的第二手指特征，经由所述控制器执行与所述当前操作模式相关的第二操作。

    METHOD FOR QUANTIFYING INITIAL CONCENTRATION OF NUCLEIC ACID FROM REAL-TIME NUCLEIC ACID AMPLIFICATION DATA
    30.
    发明申请
    METHOD FOR QUANTIFYING INITIAL CONCENTRATION OF NUCLEIC ACID FROM REAL-TIME NUCLEIC ACID AMPLIFICATION DATA 有权
    从实时核酸扩增数据定量核酸的初步浓度的方法

    公开(公告)号：US20100221728A1

    公开(公告)日：2010-09-02

    申请号：US12709774

    申请日：2010-02-22

    申请人： Kak Namkoong ,  Jin-tae Kim ,  Young-sun Lee ,  Young-a Kim

    发明人： Kak Namkoong ,  Jin-tae Kim ,  Young-sun Lee ,  Young-a Kim

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6851

    摘要： Provided is a method for quantifying an initial concentration of a nucleic acid from a real-time nucleic acid amplification data. Nucleic acid (DNA or RNA) extracted from organism or virus is amplified using an enzyme. Then, the initial concentration of the nucleic acid is found by calculating the characteristic amplification cycle number or the characteristic amplification time at which the fluorescence intensity of the nucleic acid subtracted by the background fluorescence intensity of the nucleic acid has half of its maximum value, or the characteristic amplification cycle number or the characteristic amplification time at which the amplification efficiency has the maximum or the minimum value, or the prior-to-amplification fluorescence intensity of the nucleic acid subtracted by the background fluorescence intensity of the nucleic acid. Accordingly, the initial concentration of the nucleic acid can be calculated without differentiation or integration.

    摘要翻译： 提供了从实时核酸扩增数据定量核酸的初始浓度的方法。 使用酶扩增从生物或病毒提取的核酸（DNA或RNA）。 然后，通过计算由核酸的背景荧光强度减去的核酸的荧光强度具有其最大值的一半的特征扩增循环数或特异性扩增时间来发现核酸的初始浓度，或 扩增效率具有由核酸的背景荧光强度减去的核酸的最大值或最小值或以前的扩增荧光强度的特征扩增循环数或特征扩增时间。 因此，可以在不分化或整合的情况下计算核酸的初始浓度。