公开(公告)号：US20180325532A1

公开(公告)日：2018-11-15

申请号：US15594480

申请日：2017-05-12

Applicant: Covidien LP

Inventor： Erik Skillrud ,  Daniel Deen ,  Evan Epstein ,  John Wainwright

IPC: A61B17/22 ,  A61B17/221

CPC classification number: A61B17/22 ,  A61B17/221 ,  A61B17/32056 ,  A61B2017/2217 ,  A61B2017/320716 ,  A61F2/90 ,  A61M25/0068 ,  A61M25/0082 ,  A61M25/04 ,  A61M25/09

Abstract: Devices for removing clot material from a blood vessel lumen and associated systems and methods are disclosed herein. A clot retrieving device may include, for example, an elongated member, a cover having proximal, intermediate, and distal portions. The cover may be slideably coupled to the distal region of the elongated member at a connector. The cover may have an inner layer and an outer layer. The inner layer may have (a) a first cross-sectional dimension at the proximal portion of the cover, (b) a distally increasing cross-sectional dimension along the intermediate portion of the cover, and (c) a second cross-sectional dimension at the distal portion of the cover, wherein the second cross-sectional dimension is greater than the first cross-sectional dimension. The outer layer may have a cross-sectional dimension that is generally constant along the distal portion and the intermediate portion of the cover.

公开(公告)号：US20180110797A1

公开(公告)日：2018-04-26

申请号：US15299929

申请日：2016-10-21

Applicant: Covidien LP

Inventor： Junwei Li ,  Gaurav Girdhar ,  John Wainwright ,  Yves Bayon ,  Ariana Pagani

IPC: A61K31/722 ,  A61M25/10 ,  A61M5/145

Abstract: A method for treating an aneurysm in accordance with a particular embodiment of the present technology includes intravascularly delivering a mixture including a biopolymer (e.g., chitosan) and a chemical crosslinking agent (e.g., genipin) to an aneurysm. The method further includes mixing the biopolymer and the chemical crosslinking agent to initiate chemical crosslinking of the biopolymer. The mixture is delivered to the aneurysm via a lumen and an exit port of a catheter while the chemical crosslinking is ongoing. The mixture exits the catheter as a single cohesive strand that at least partially agglomerates to form a mass occupying at least 75% of a total internal volume of the aneurysm. During delivery of the mixture, the method includes expanding a tubular flow diverter to reinforce a neck of the aneurysm.

公开(公告)号：US20170119557A1

公开(公告)日：2017-05-04

申请号：US15404760

申请日：2017-01-12

Applicant: Covidien LP

Inventor： John Wainwright ,  Todd Mendelson ,  Kurt Haggstrom ,  Masoud Molaei ,  Victoria Schuman ,  Min-shyan Sheu

IPC: A61F2/90 ,  B05D3/04 ,  B05D3/02 ,  B05D1/18

CPC classification number: A61F2/90 ,  A61F2/07 ,  A61F2/966 ,  A61F2002/072 ,  A61F2002/823 ,  A61F2002/9665 ,  A61F2210/0076 ,  A61F2230/0069 ,  A61F2250/0023 ,  A61F2250/0067 ,  A61F2310/00389 ,  B05D1/18 ,  B05D3/0272 ,  B05D3/04

Abstract: Medical devices that include a tubular member with a plurality of braided filaments, each filament crossing another of the filaments at a respective crossing point forming sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm, the pores have an average pore size that is less than or equal to about 500 microns when the tubular member is in an expanded state, the filaments possessing antithrombogenic surfaces to increase antithrombogenicity of the medical device with pores substantially free of webs formed by antithrombogenic material, such that fewer than 5% of the crossing points have webs formed by antithrombogenic material thereby permitting the pores to be substantially free of webs.

公开(公告)号：US09610180B2

公开(公告)日：2017-04-04

申请号：US14578554

申请日：2014-12-22

Applicant: COVIDIEN LP

Inventor： Anh Cam ,  Michael Losordo ,  Jianlu Ma ,  Luong Nguyen ,  Sanjay Shrivastava ,  John Wainwright ,  Xiaoling Zhao

IPC: A61F2/06 ,  A61F2/90 ,  A61F2/95 ,  A61B17/12 ,  A61F2/82

CPC classification number: A61F2/90 ,  A61B17/12118 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/12168 ,  A61B17/12172 ,  A61B2017/00867 ,  A61B2017/1209 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/823 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/0034 ,  A61F2230/0054 ,  A61F2230/0069 ,  A61F2230/0093

Abstract: Vascular remodeling devices can include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchor the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection.

公开(公告)号：US20150148882A1

公开(公告)日：2015-05-28

申请号：US14087459

申请日：2013-11-22

Applicant: Covidien LP

Inventor： Xiaodong Ma ,  Min-Shyan Sheu ,  Lincoln Eramo ,  John Wainwright ,  Junwei Li

IPC: A61F2/82

CPC classification number: A61F2/82 ,  A61F2/06 ,  A61F2/90 ,  A61F2240/001 ,  A61L31/022 ,  A61L31/10 ,  A61L31/146 ,  A61L31/16 ,  A61L33/0088 ,  A61L33/064 ,  A61L2300/42 ,  A61L2400/18 ,  A61L2420/02 ,  B05D1/18 ,  B05D3/142

Abstract: Methods for applying layers to medical devices and related devices are provided. Such devices can include stents. For example, the device can include a sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm. The device can have an anti-thrombogenic outer layer distributed over at least a portion of the device.

Abstract translation: 提供了将层应用于医疗设备和相关设备的方法。 这样的装置可以包括支架。 例如，该装置可以包括在侧壁中的侧壁和多个孔，其尺寸被设计成当管状构件定位时阻止血液通过侧壁流入动脉瘤至足以导致动脉瘤血栓形成和愈合的程度 在血管中并且与动脉瘤相邻。 该装置可以具有分布在装置的至少一部分上的抗血栓形成外层。

公开(公告)号：US12256936B2

公开(公告)日：2025-03-25

申请号：US18324017

申请日：2023-05-25

Applicant: Covidien LP

Inventor： Junwei Li ,  John Wainwright ,  Gaurav Girdhar ,  Stephen Sosnowski

IPC: A61B17/12 ,  A61B17/00 ,  A61B90/00 ,  B23P19/04

Abstract: Systems and methods for treating an aneurysm in accordance with embodiments of the present technology include intravascularly delivering an occlusive member to an aneurysm cavity and deforming a shape of the occlusive member via introduction of an embolic element to a space between the occlusive member and an inner surface of the aneurysm wall.

公开(公告)号：US12239423B2

公开(公告)日：2025-03-04

申请号：US17459713

申请日：2021-08-27

Applicant: Covidien LP

Inventor： Randal C. Schulhauser ,  Jonathon E. Giftakis ,  Eric J. Panken ,  John Wainwright ,  Nathalie Virag ,  Paul G. Krause ,  Yong K. Cho ,  Scott DeFoe ,  Avram Scheiner ,  Ekaterina M. Ippolito ,  David A. Anderson ,  Saul E. Greenhut ,  Mark R. Boone ,  Richard J. O'Brien

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/021 ,  A61B5/024 ,  A61B5/0245 ,  A61B5/11 ,  A61B5/291

Abstract: A system comprises a sensor device and processing circuitry. The sensor device comprises a housing configured to be disposed above shoulders of a patient, a plurality of electrodes on the housing, a motion sensor, and sensing circuitry configured to sense a brain electrical signal and a cardiac electrical signal via the electrodes, and a motion signal via the motion sensor. The processing circuitry is configured to determine values over time of one or more parameters from the brain electrical signal, determine values over time of one or more parameters from the cardiac electrical signal, and generate at least one of a detection, prediction, or a classification a condition of the patient based on the values and the motion signal.

公开(公告)号：US20230294223A1

公开(公告)日：2023-09-21

申请号：US18324017

申请日：2023-05-25

Applicant: Covidien LP

Inventor： Junwei Li ,  John Wainwright ,  Gaurav Girdhar ,  Stephen Sosnowski

IPC: B23P19/04 ,  A61B17/12

CPC classification number: B23P19/047 ,  A61B17/12172 ,  A61B17/12113 ,  A61B17/12186 ,  A61B17/1214 ,  A61B17/12031 ,  A61B17/12145 ,  A61B2017/00526

Abstract: Systems and methods for treating an aneurysm in accordance with embodiments of the present technology include intravascularly delivering an occlusive member to an aneurysm cavity and deforming a shape of the occlusive member via introduction of an embolic element to a space between the occlusive member and an inner surface of the aneurysm wall.

公开(公告)号：US20230149021A1

公开(公告)日：2023-05-18

申请号：US17455646

申请日：2021-11-18

Applicant: Covidien LP

Inventor： John Wainwright ,  Hoai Nguyen ,  James Davidson

IPC: A61B17/12

CPC classification number: A61B17/12109 ,  A61B17/1214 ,  A61B17/12168 ,  A61B2017/1205

Abstract: Retrieval of material from vessel lumens can be improved by use of a distal element comprising an expandable mesh. a treatment device includes an elongated member having a proximal portion and a distal portion configured to be positioned within a blood vessel at a treatment site at or near a thrombus. A distal element comprising a plurality of woven filaments defining a shaft at a proximal portion and a body distal of the shaft is coupled to the distal portion of the elongated member via a connection assembly. In an expanded state, at least a portion of the distal element is configured to be in apposition with the blood vessel wall at the treatment site to anchor or stabilize the elongated member with respect to the blood vessel. The distal element can be electrically coupled to an extracorporeal current generator.

公开(公告)号：US20220296174A1

公开(公告)日：2022-09-22

申请号：US17204573

申请日：2021-03-17

Applicant: Covidien LP

Inventor： Patrick W. Kinzie ,  David L. Probst ,  Mohsen Askarinya ,  Aaron Gilletti ,  Richard J. O'Brien ,  Mark J. Phelps ,  Randal C. Schulhauser ,  John Wainwright

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/361 ,  A61B5/282 ,  A61B5/29

Abstract: A system comprises electrocardiogram sensing, glucose sensing circuitry, and processing circuitry. The sensing circuitry is configured to sense an electrocardiogram of a patient. The glucose sensing circuitry is configured to sense glucose levels of the patient. The processing circuitry configured to detect atrial fibrillation of the patient during a time unit based on the electrocardiogram of the patient, determine a first metric, wherein the first metric is associated with atrial fibrillation the patient experiences during the time unit, determine a second metric, wherein the second metric is associated with glucose levels of the patient during the time unit, and generate a health metric, wherein the health metric is determined based on the first and second metrics.