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27 条记录 (耗时 0.021 秒)

    Apparatus and Methods for the Measurement of Cardiac Output
    21.
    发明申请
    Apparatus and Methods for the Measurement of Cardiac Output 有权
    用于测量心输出量的仪器和方法

    公开(公告)号：US20090227885A1

    公开(公告)日：2009-09-10

    申请号：US12249886

    申请日：2008-10-10

    申请人： Guy Russell Lowery ,  William J. Grande

    发明人： Guy Russell Lowery ,  William J. Grande

    IPC分类号： A61M16/04 ,  A61B5/029 ,  B05D5/12

    CPC分类号： A61B5/029 ,  A61B5/0421 ,  A61B5/0535 ,  A61B5/0538 ,  A61B5/6853 ,  A61B2562/0209 ,  A61B2562/046 ,  A61B2562/125 ,  H05K1/0284 ,  H05K1/117 ,  H05K1/141 ,  H05K1/147 ,  H05K3/4069 ,  H05K2201/0949

    摘要： The current invention provides an endotracheal tube fabricated with an array of electrodes disposed on an inflatable cuff on the tube. The array of electrodes includes multiple sense electrodes and a current electrode. The array of electrodes on the inflatable cuff is applied using a positive displacement dispensing system, such as a MicroPen®. A ground electrode is disposed on the tube approximately midway between the inflatable cuff and the midpoint of the endotracheal tube. The endotracheal tube is partially inserted into a mammalian subject's airway such that when the inflatable cuff is inflated, thereby fixing the tube in position, the array of electrodes is brought into close contact with the tracheal mucosa in relative proximity to the aorta. The endotracheal tube is useful in the measurement of cardiac parameters such as cardiac output.

    摘要翻译： 本发明提供一种气管插管，其制造有设置在管上的可充气袖带上的电极阵列。 电极阵列包括多个感测电极和电流电极。 使用正位移分配系统（例如MicroPen）来施加充气袖带上的电极阵列。 接近电极位于可充气袖带和气管插管的中点之间大致中间的管上。 气管插管被部分地插入到哺乳动物受试者的气道中，使得当可膨胀的袖带被充气时，从而将管固定在适当位置，使电极阵列与气管粘膜紧密接触，相对接近主动脉。 气管内管可用于测量心脏参数，如心输出量。

    Dry powder electrostatic deposition method and apparatus
    22.
    发明授权
    Dry powder electrostatic deposition method and apparatus 失效

    公开(公告)号：US07497910B2

    公开(公告)日：2009-03-03

    申请号：US10177209

    申请日：2002-06-21

    申请人： William Mey ,  William J. Grande

    发明人： William Mey ,  William J. Grande

    IPC分类号： B05C5/02

    CPC分类号： B05C5/02 ,  A61K9/2893 ,  B05B5/087 ,  B05B5/1683 ,  B05D1/06 ,  B05D3/207

    摘要： A method and apparatus are presented for electrostatic deposition of dry powder to a tablet, capsule, or a specific area of any of a wide range of pharmaceutical substrates. The apparatus includes: a magnetic brush having a rotatable multi-pole magnetic core and a stationary outer shell; a developer supply for supplying a magnetic developer powder, consisting of a magnetic carrier particles and pharmaceutical dry powder particles, to the magnetic brush; a print head on the outer shell; a tablet or other pharmaceutical substrate arranged in spaced relation to the print head to define a pharmaceutical powder transfer region through which the substrate can be moved. The print head includes an array of microchannels for forming a plurality of parallel lines of developer in the channels, a corresponding plurality of transfer electrodes located in the microchannels for selectively transferring pharmaceutical powder from the lines to a substrate, driver circuitry for generating and applying transfer signals to the transfer electrodes, a power supply connection for applying power to the drive circuitry, a print signal input connection for applying print signals to the print head, and a logic and control circuit for applying the print signals to the drive circuitry.In one embodiment the width of an individual microchannel print head and the rotating multipole magnetic core is approximately the same dimension as the tablet or substrate to which pharmaceutical powder is to be deposited. In a further embodiment individual microchannel print heads can be arranged along the length of the shell to simultaneously deposit pharmaceutical powder to an array of tablets. In still a further embodiment the microchannel print head is shaped to conform to the tablet or capsule geometry to enhance deposition in three dimensions.In another embodiment the microchannel print head is formed on a silicon substrate onto which are also formed a multiplicity of individual drive circuits connected through separate conductive paths to individual transfer electrodes. In a further embodiment all the microelectronic circuitry necessary for the operation of the integrated microchannel print head is formed on the silicon substrate.

    Method for selective transfer of a color organic layer
    27.
    发明授权
    Method for selective transfer of a color organic layer 失效
    选择性转移彩色有机层的方法

    公开(公告)号：US5851709A

    公开(公告)日：1998-12-22

    申请号：US961808

    申请日：1997-10-31

    申请人： William J. Grande ,  Paul J. Fleming ,  Ching W. Tang

    发明人： William J. Grande ,  Paul J. Fleming ,  Ching W. Tang

    IPC分类号： B41J2/44 ,  B41J2/45 ,  B41J2/455 ,  B41M5/382 ,  G02B5/20 ,  G02F1/1335 ,  H01L27/146 ,  H01L27/32 ,  H01L31/0216 ,  H01L51/00 ,  H01L51/56

    CPC分类号： B41M5/38214 ,  G02B5/201 ,  H01L31/02162 ,  H01L51/0013 ,  H01L27/3211 ,  H01L51/56

    摘要： A method for selective transfer of a color organic layer from a donor layer onto a device having an array of pixels with each pixel formed from color subpixels, includes the steps of providing a substrate having opposing first and second surfaces; forming a light transmissive heat insulating layer over the first surface of the substrate; forming a light absorbing layer over the heat insulating layer; providing the substrate with an array of openings extending from the second surface to the heat insulating layer, the number and positions of the openings corresponding to the number and positions of the color subpixels of the device, and each opening having a size equal to or smaller than the size of the color subpixel. The method also includes providing a transferable color forming organic donor layer formed on the light absorbing layer; positioning the device in contact or close proximity to the donor layer in an oriented relationship between the openings in the substrate and the corresponding color subpixels on the device; and employing a source of radiation for producing sufficient heat at the light absorbing layer over the openings to cause the selective transfer of portions of the transferable color forming organic donor layer to the corresponding color subpixels of the device.

    摘要翻译： 一种将彩色有机层从供体层选择性转移到具有由彩色子像素形成的每个像素的像素阵列的器件的方法包括以下步骤：提供具有相对的第一和第二表面的衬底; 在所述基板的所述第一表面上形成透光绝热层; 在绝热层上形成光吸收层; 向所述基板提供从所述第二表面延伸到所述绝热层的开口阵列，所述开口的数量和位置对应于所述装置的彩色子像素的数量和位置，并且每个开口的尺寸等于或小于 比颜色子像素的大小。 该方法还包括提供形成在光吸收层上的可转移的形成颜色的有机供体层; 将器件定位成与衬底中的开口和器件上相应的彩色子像素之间的定向关系接触或靠近施主层; 并且使用辐射源在所述开口处的光吸收层处产生足够的热量，以使所述可转移的形成颜色的有机施主层的部分的选择性转移到所述器件的相应颜色子像素。