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    Microbial conversion of CO2 and other C1 substrates to protein and meat substitute products
    24.
    发明授权
    Microbial conversion of CO2 and other C1 substrates to protein and meat substitute products 有权

    公开(公告)号：US11203738B2

    公开(公告)日：2021-12-21

    申请号：US16716398

    申请日：2019-12-16

    Applicant: Kiverdi, Inc.

    Inventor： Lisa Dyson ,  John Reed ,  Jil Geller ,  Sonali Hande

    IPC: C12N1/20 ,  C12P1/04 ,  C12P7/64 ,  C12P13/04 ,  C12P21/02

    Abstract: Microorganisms and bioprocesses are provided that convert gaseous substrates, such as renewable H2 and waste CO2 producer gas, or syngas into high-protein biomass that may be used directly for human nutrition, or as a nutrient for plants, fungi, or other microorganisms, or as a source of soil carbon, nitrogen, and other mineral nutrients. Renewable H2 used in the processes described herein may be generated by electrolysis using solar or wind power. Producer gas used in the processes described herein may be derived from sources that include gasification of waste feedstock and/or biomass residue, waste gas from industrial processes, or natural gas, biogas, or landfill gas.

    Engineered CO2-Fixing Chemotrophic Microorganisms Producing Carbon-Based Products and Methods of Using the Same
    28.
    发明申请
    Engineered CO2-Fixing Chemotrophic Microorganisms Producing Carbon-Based Products and Methods of Using the Same 审中-公开
    工程化的CO2固定化学生物微生物生产碳基产品及其使用方法

    公开(公告)号：US20150017694A1

    公开(公告)日：2015-01-15

    申请号：US14388756

    申请日：2013-03-15

    Applicant: Kiverdi, Inc.

    Inventor： Itzhak Kurek ,  John S. Reed ,  Lisa Dyson ,  Michael Siani-Rose ,  Henrik Fyrst ,  Christer Jansson ,  David Galgoczy

    IPC: C12P7/64 ,  C12N15/74

    CPC classification number: C12P7/649 ,  C12N1/20 ,  C12N9/0008 ,  C12N9/0083 ,  C12N9/16 ,  C12N9/88 ,  C12P5/002 ,  C12P5/026 ,  C12P7/04 ,  C12P7/6409 ,  C12Y114/99033 ,  C12Y301/02014 ,  Y02E50/13 ,  Y02P20/52

    Abstract: Disclosed herein are microorganisms containing exogenous or heterologous nucleic acid sequences, wherein the microorganisms are capable of growing on gaseous carbon dioxide, gaseous hydrogen, syngas, or combinations thereof. In some embodiments the microorganisms are chemotrophic bacteria that produce or secrete at least 10% of lipid by weight. Also disclosed are methods of fixing gaseous carbon into organic carbon molecules useful for industrial processes. Also disclosed are methods of manufacturing chemicals or producing precursors to chemicals useful in jet fuel, diesel fuel, and biodiesel fuel. Exemplary chemicals or precursors to chemicals useful in fuel production are alkanes, alkenes, alkynes, fatty acid alcohols, fatty acid aldehydes, desaturated hydrocarbons, unsaturated fatty acids, hydroxyl acids, or diacids with carbon chains between six and thirty carbon atoms long. Also disclosed are microorganisms and methods using disclosed microorganisms for the production of butanediol and its chemical precursors in low-oxygen or anaerobic fermentation. Also disclosed are microorganisms and methods using disclosed microorganisms for generating hydroxylated fatty acids in microbes through the transfer of enzymes that are known to hydroxylate fatty acids in plants or microbes. Also disclosed are microorganisms and methods using disclosed microorganisms for the production of shorter-chain fatty acids in microbes through the introduction of exogenous fatty acyl-CoA binding proteins.

    Abstract translation: 本文公开了含有外源或异源核酸序列的微生物，其中微生物能够在气态二氧化碳，气态氢，合成气或其组合上生长。 在一些实施方案中，微生物是产生或分泌至少10重量％脂质的化学营养细菌。 还公开了将气态碳固定在可用于工业过程的有机碳分子中的方法。 还公开了制造化学品或生产用于喷气燃料，柴油燃料和生物柴油燃料的化学品的前体的方法。 用于燃料生产的化学品或化学物质的示例是烷烃，烯烃，炔烃，脂肪酸醇，脂肪酸醛，去饱和烃，不饱和脂肪酸，羟基酸或具有6-30个碳原子长的碳链的二酸。 还公开了使用公开的微生物在低氧或厌氧发酵中生产丁二醇及其化学前体的微生物和方法。 还公开了微生物和使用公开的微生物通过转移在植物或微生物中羟基化脂肪酸已知的酶在微生物中产生羟化脂肪酸的微生物和方法。 还公开了微生物和使用公开的微生物通过引入外源性脂肪酰基-CoA结合蛋白在微生物中生产短链脂肪酸的微生物和方法。

    USE OF OXYHYDROGEN MICROORGANISMS FOR NON-PHOTOSYNTHETIC CARBON CAPTURE AND CONVERSION OF INORGANIC AND/OR C1 CARBON SOURCES INTO USEFUL ORGANIC COMPOUNDS
    30.
    发明申请
    USE OF OXYHYDROGEN MICROORGANISMS FOR NON-PHOTOSYNTHETIC CARBON CAPTURE AND CONVERSION OF INORGANIC AND/OR C1 CARBON SOURCES INTO USEFUL ORGANIC COMPOUNDS 有权
    用于非光催化性碳捕获的氧化微生物和无机碳和/或碳碳源转化为有效的有机化合物

    公开(公告)号：US20140024091A1

    公开(公告)日：2014-01-23

    申请号：US14033013

    申请日：2013-09-20

    Applicant: Kiverdi, Inc.

    Inventor： John S. Reed ,  Lisa Dyson

    IPC: C12P7/62 ,  C12M1/00

    CPC classification number: C12P7/625 ,  C12M23/34 ,  C12M29/02 ,  C12M29/08 ,  C12M29/18 ,  C12M29/20 ,  C12M43/04 ,  C12M47/02 ,  C12N1/12 ,  C12N1/20 ,  C25B1/04 ,  C25B15/02 ,  Y02E60/366 ,  Y02P20/133

    Abstract: Compositions and methods for a hybrid biological and chemical process that captures and converts carbon dioxide and/or other forms of inorganic carbon and/or C1 carbon sources including but not limited to carbon monoxide, methane, methanol, formate, or formic acid, and/or mixtures containing C1 chemicals including but not limited to various syngas compositions, into organic chemicals including biofuels or other valuable biomass, chemical, industrial, or pharmaceutical products are provided. The present invention, in certain embodiments, fixes inorganic carbon or C1 carbon sources into longer carbon chain organic chemicals by utilizing microorganisms capable of performing the oxyhydrogen reaction and the autotrophic fixation of CO2 in one or more steps of the process.

    Abstract translation: 捕获并转化二氧化碳和/或其他形式的无机碳和/或C1碳源的混合生物和化学过程的组合物和方法，包括但不限于一氧化碳，甲烷，甲醇，甲酸盐或甲酸，和/ 或包含C1化学品（包括但不限于各种合成气组合物）的混合物，包括生物燃料或其他有价值的生物质，化学，工业或医药产品的有机化学品。 在某些实施方案中，本发明通过在该方法的一个或多个步骤中利用能够进行氢氧化反应和CO 2的自养固定的微生物将无机碳或C1碳源固定在较长的碳链有机化学品中。

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