公开(公告)号：US20050272038A1

公开(公告)日：2005-12-08

申请号：US10522912

申请日：2003-07-17

申请人： Ruediger Ridder ,  Peter Martin ,  Matthias Herkert ,  Anja Reichert ,  Marcus Trunk-Gehmacher

发明人： Ruediger Ridder ,  Peter Martin ,  Matthias Herkert ,  Anja Reichert ,  Marcus Trunk-Gehmacher

IPC分类号： A61K38/08 ,  A61K38/17 ,  A61K39/00 ,  C07K14/47 ,  G01N33/574 ,  C12Q1/68 ,  C12P19/34

CPC分类号： A61K38/1709 ,  A61K38/08 ,  A61K39/00 ,  C07K14/4703 ,  G01N33/57484

摘要： The present invention relates to a method for improved diagnosis of cervical lesions based on detection of gene products encoded by the INK4a gene locus. According to the present invention an improvement in diagnosis may be achieved by assessing the presence or absence or the level of overexpression of at least two different gene products encoded by the INK4a gene locus. In another aspect the present invention relates to peptides derived from cell cycle regulatory proteins, the expression of which is altered in association with tumors in individuals. These peptides according to the present invention may be used for detection and therapy of tumors. For detection purposes the peptides may for example be used to detect antibodies directed against said peptides. In therapeutic respect the peptides may be used for immunotherapy or vaccination approaches. In therapeutic and diagnostic respect the peptides may be used in combination with one or more peptides derived from tumor associated proteins.

摘要翻译： 本发明涉及一种基于由INK4a基因座编码的基因产物的检测来改善子宫颈病变诊断的方法。 根据本发明，可以通过评估由INK4a基因座编码的至少两种不同基因产物的过表达的存在或不存在或水平来实现诊断的改善。 在另一方面，本发明涉及衍生自细胞周期调节蛋白的肽，其表达与个体中的肿瘤相关联地改变。 根据本发明的这些肽可以用于肿瘤的检测和治疗。 为了检测目的，肽可以例如用于检测针对所述肽的抗体。 在治疗方面，肽可以用于免疫治疗或疫苗接种方法。 在治疗和诊断方面，肽可以与一种或多种衍生自肿瘤相关蛋白的肽组合使用。

公开(公告)号：US20050252175A1

公开(公告)日：2005-11-17

申请号：US10520092

申请日：2003-07-18

申请人： Peter Martin

发明人： Peter Martin

IPC分类号： B65B9/10 ,  B31B1/25 ,  B31B1/74 ,  B65B9/20 ,  B65B61/02 ,  B65D5/42 ,  B65D25/20 ,  B65B9/00 ,  B65B57/02

CPC分类号： B65D5/4216 ,  B31B50/006 ,  B31B50/254 ,  B65B9/20 ,  B65B61/025

摘要： A packaging for liquids is made of a flat packaging material. This material has fold lines (6) and a mark (11) placed on a wall area of the packaging. The invention also relates to a blank and to a method for producing a packaging of this type, in which fold lines (6) and the mark (11) are placed in a moving packaging web of material. Afterwards, the web of material is shaped, filled and closed. The aim of the invention is to simplify the production of the packaging and to provide it with a more economical and more precise design. To this end, the invention provides that the mark (11) is formed by stamp lines (25), which lie on a plane and of which at least two straight stamp lines (25) intersect at least in the extension thereof. It is advantageous when the mark (11) has at least one centra-symmetric structure. According to the method, the invention provides that the mark (11) is made by the placement of stamp lines (25) so that the cross-section of the material is U-shaped after stamping, whereby the thickness of the material remains essentially the same.

摘要翻译： 液体包装由扁平包装材料制成。 该材料具有折叠线（6）和放置在包装的壁面上的标记（11）。 本发明还涉及生产这种类型的包装的坯料和方法，其中折叠线（6）和标记（11）放置在移动的材料包装纤维网中。 之后，材料网被成型，填充和封闭。 本发明的目的是简化包装的生产并为其提供更经济和更精确的设计。 为此，本发明提供了标记（11）由位于平面上且至少两条直线印刷线（25）至少在其延伸部相交处的印模线（25）形成。 标记（11）具有至少一个中心对称结构是有利的。 根据该方法，本发明提供了标记（11）通过放置印模线（25）制成，使得材料的横截面在冲压之后是U形的，由此材料的厚度基本保持为 相同。

公开(公告)号：US20050104089A1

公开(公告)日：2005-05-19

申请号：US10785833

申请日：2004-02-23

申请人： Michael Engelmann ,  Calvin Chao ,  Tzu-Chiang Hsieh ,  Peter Martin ,  Milam Pender

发明人： Michael Engelmann ,  Calvin Chao ,  Tzu-Chiang Hsieh ,  Peter Martin ,  Milam Pender

IPC分类号： H01L27/00 ,  H01L27/10 ,  H01L27/146 ,  H01L29/76 ,  H01L31/00 ,  H01L31/062 ,  H01L31/105 ,  H01L31/113

CPC分类号： G01J5/02 ,  G01J5/024 ,  G01J5/026 ,  G01J5/04 ,  G01J5/046 ,  G01J5/22 ,  G01J5/52 ,  G01J2005/0077 ,  H01L27/14609 ,  H01L27/14621 ,  H01L27/1463 ,  H01L27/14632 ,  H01L27/14636 ,  H01L27/14643 ,  H01L27/14645 ,  H01L27/14649 ,  H01L27/14687 ,  H01L27/14689 ,  H01L27/14692 ,  H01L31/03685 ,  H01L31/03687 ,  H01L31/1055 ,  H01L31/109 ,  H01L31/113 ,  H04N5/2351 ,  H04N5/2353 ,  H04N5/33 ,  H04N5/332 ,  H04N5/365 ,  H04N5/3651 ,  H04N5/374 ,  H04N5/37455 ,  H04N5/378 ,  Y02E10/545 ,  Y02E10/548

摘要： A MOS or CMOS sensor for high performance imaging in broad spectral ranges including portions of the infrared spectral band. These broad spectral ranges may also include portions or all of the visible spectrum, therefore the sensor has both daylight and night vision capabilities. The sensor includes a continuous multi-layer photodiode structure on a many pixel MOS or CMOS readout array where the photodiode structure is chosen to include responses in the near infrared spectral ranges. A preferred embodiment incorporates a microcrystalline copper indium diselenide/cadmium sulfide photodiode structure on a CMOS readout array. An alternate preferred embodiment incorporates a microcrystalline silicon germanium photodiode structure on a CMOS readout array. Each of these embodiments provides night vision with image performance that greatly surpasses the GEN III night vision technology in terms of enhanced sensitivity, pixel size and pixel count. Further advantages of the invention include low electrical bias voltages, low power consumption, compact packaging, and radiation hardness. In special preferred embodiments CMOS stitching technology is used to provide multi-million pixel focal plane array sensors. One embodiments of the invention made without stitching is a two-million pixel sensor. Other preferred embodiments available using stitching techniques include sensors with 250 million (or more) pixels fabricated on a single wafer. A particular application of these very high pixel count sensors is as a focal plane array for a rapid beam steering telescope in a low earth orbit satellite useful for tracking over a 1500-meter wide track with a resolution of 0.3 meter.

摘要翻译： 一种用于在宽光谱范围内进行高性能成像的MOS或CMOS传感器，包括红外光谱带的部分。 这些宽光谱范围还可以包括可见光谱的部分或全部，因此传感器具有日光和夜视能力。 该传感器包括在多个像素MOS或CMOS读出阵列上的连续多层光电二极管结构，其中光电二极管结构被选择为包括在近红外光谱范围内的响应。 优选实施例在CMOS读出阵列上结合微晶铜铟二硒化物/硫化镉光电二极管结构。 替代的优选实施例在CMOS读出阵列上结合了微晶硅锗光电二极管结构。 这些实施例中的每一个为增强的灵敏度，像素尺寸和像素数量提供了大大超过GEN III夜视技术的图像性能的夜视。 本发明的另外的优点包括低偏置电压，低功耗，紧凑的封装和辐射硬度。 在特别优选实施例中，CMOS拼接技术用于提供数百万像素焦平面阵列传感器。 没有拼接的本发明的一个实施例是200万像素传感器。 使用缝合技术可获得的其它优选实施例包括在单个晶片上制造的具有2.5亿（或更多）像素的传感器。 这些非常高的像素数传感器的特定应用是用于在低地球轨道卫星中的快速波束转向望远镜的焦平面阵列，其用于在分辨率为0.3米的1500米宽的轨道上进行跟踪。

公开(公告)号：US06725132B2

公开(公告)日：2004-04-20

申请号：US10175875

申请日：2002-06-20

申请人： Scott Frankel ,  Peter Martin ,  Eric Hardt

发明人： Scott Frankel ,  Peter Martin ,  Eric Hardt

IPC分类号： G05D2300

CPC分类号： G05D23/1902

摘要： A cooling fan including a fan module, a microcontroller, and a bus interface. The microcontroller is coupled to the fan module and is capable of adjusting a speed of the cooling fan based on a status of a second cooling fan and adjusting the speed of the cooling fan based on a temperature detected. The bus interface is in communication with the microcontroller, the second cooling fan, and the system to receive and output data.

摘要翻译： 包括风扇模块，微控制器和总线接口的冷却风扇。 微控制器耦合到风扇模块，并且能够基于第二冷却风扇的状态来调节冷却风扇的速度，并且基于检测到的温度来调节冷却风扇的速度。 总线接口与微控制器，第二个冷却风扇和系统进行通信，以接收和输出数据。

公开(公告)号：US06258814B1

公开(公告)日：2001-07-10

申请号：US09688313

申请日：2000-10-13

申请人： Peter Martin

发明人： Peter Martin

IPC分类号： A61K31495

CPC分类号： A61K9/0043 ,  A61K31/495

摘要： Disclosed is a method of inducing sleep in a human suffering from a sleeping disorder comprising administering to the human a therapeutically effective amount of cetirizine hydrochloride once daily. Also disclosed is pharmaceutical compositions concerning the same.

摘要翻译： 公开了在患有睡眠障碍的人中诱导睡眠的方法，其包括每天向人施用治疗有效量的盐酸西替利嗪。 还公开了涉及其的药物组合物。

公开(公告)号：US5998794A

公开(公告)日：1999-12-07

申请号：US947380

申请日：1997-10-08

申请人： Brett Spivey ,  Paul Johnson ,  Lee Morsell ,  Peter Martin

发明人： Brett Spivey ,  Paul Johnson ,  Lee Morsell ,  Peter Martin

IPC分类号： H01L27/146 ,  G01T1/24

CPC分类号： H01L27/14634 ,  H01L27/1465

摘要： A semiconductor imaging device comprising MOS or CMOS pixel circuits having pixel pads separated by insulating material and having a conductive migration blocking layer applied over the pixel pads. The conductive migration blocking layer comprises an electrically conductive material that is inert with respect to selected photoelectric conversion layer materials, and may be formed as individual contacts, or formed as a deposited layer and etched to form distinct pixels covering the underlying pixel pad material. Thereafter, a photoelectric conversion layer is applied over the migration blocking layer material. The basic device is completed by applying a field electrode layer over the photoelectric conversion layer.

摘要翻译： 一种半导体成像装置，包括MOS或CMOS像素电路，其具有由绝缘材料分隔并具有施加在像素焊盘上的导电迁移阻挡层的像素焊盘。 导电迁移阻挡层包括相对于所选择的光电转换层材料为惰性的导电材料，并且可以形成为单独的触点，或形成为沉积层，并被蚀刻以形成覆盖下面的像素焊盘材料的不同的像素。 此后，在迁移阻挡层材料上施加光电转换层。 通过在光电转换层上施加场电极层来完成基本装置。

公开(公告)号：US5551778A

公开(公告)日：1996-09-03

申请号：US502556

申请日：1995-07-14

申请人： Gunter Hauke ,  Rainer Specht ,  Ralf Krotz ,  Reiner Funk ,  Peter Martin ,  Berthold Nies

发明人： Gunter Hauke ,  Rainer Specht ,  Ralf Krotz ,  Reiner Funk ,  Peter Martin ,  Berthold Nies

IPC分类号： A61L24/00 ,  A61B50/00 ,  A61F2/46 ,  B01F11/00 ,  B01F13/00 ,  B01F13/06 ,  B01F15/02

CPC分类号： B01F15/0205 ,  B01F11/0082 ,  B01F13/002 ,  B01F15/00974 ,  B01F15/0206 ,  B01F15/0224 ,  B01F15/0278 ,  A61B2050/0066 ,  A61F2002/4685 ,  B01F13/06 ,  B01F15/0266 ,  B01F2215/0029

摘要： A device for mixing and discharging bone cement has a mixing cylinder which consists of two cylinder parts and in which an openworked mixing plunger can be moved axially. The lower cylinder part is sealed off by a discharging plunger. A separating plunger is arranged axially displaceably in the mixing cylinder between the mixing plunger and the discharging plunger, which separating plunger seals off the one cylinder part before the two cylinder parts are connected. The separating plunger has through-flow channels through which a liquid monomer can flow from the lower cylinder part to a pulverulent polymer in the upper cylinder part at the start of the mixing procedure.

摘要翻译： 用于混合和排出骨水泥的装置具有由两个气缸部分组成的混合缸，其中透气混合柱塞可以轴向移动。 下部气缸部分由排放柱塞密封。 分离柱塞在混合柱塞之间轴向位移地布置在混合柱塞和排出柱塞之间，在两个气缸部分连接之前，分离柱塞将一个气缸部分分离出来。 分离柱塞具有通流通道，液体单体可以在混合过程开始时从下汽缸部分流到上汽缸部分中的粉状聚合物。

公开(公告)号：US5113785A

公开(公告)日：1992-05-19

申请号：US590902

申请日：1990-10-01

申请人： Peter Martin

发明人： Peter Martin

IPC分类号： B23Q7/03 ,  B05C13/02 ,  B65G15/22 ,  B65G17/32 ,  B65G43/08 ,  B65G47/52 ,  B65G47/57 ,  B65G47/74 ,  B65G47/84 ,  B65H29/16 ,  H05K13/00 ,  H05K13/02

CPC分类号： H05K13/0061 ,  Y10S118/04

摘要： A transport device (1) for boards (2) or board-shaped workpieces, especially those having a sensitive surface, preferably for circuit boards which are coated with plastics material, for example UV-hardenable plastics material, with lacquer or the like and then dried, is constructed as a circulating coating system. The device (1) has holders (3) for taking hold of the boards (2) at the edges (2a) thereof when they are being handled, and advancing means, advantageously in the form of chains, for transporting those holders (3). The holder (3) has two parallel bars (10) on each of which there are provided two rows (11, 12) of prongs (13) arranged in the form of a rake, the prongs (13) of the one row (11) of a bar (10) forming an acute angle with those of the second row (12) of that bar (10) and the two rows (11, 12) accordingly being arranged with respect to each other in a "V" shape when viewed in cross-section. The free ends of the prongs (13) of the one bar (10) point towards the free ends of the prongs (13) of the other bar (10). The two bars (10) extend from a common carrier (14) which holds and connects them, on which carrier there is provided at the end from which the bars (10) extend an end-face stop (15) for the boards (2) which has two limbs (15a, 15b) extending at an obtuse angle to each other towards the bars (10), so that a rectangular board being supported abuts only by the corners that are towards that stop (15) (FIG. 1).

摘要翻译： 用于板（2）或板状工件的输送装置（1），特别是具有敏感表面的输送装置（1），优选用于涂覆有塑料材料的电路板，例如UV可硬化塑料材料，其中涂漆或类似物，然后 干燥，被构造为循环涂层体系。 装置（1）具有用于在其被处理时在其边缘（2a）处抓住板（2）的保持器（3）和有利地为链条形式的推进装​​置，用于运输这些支架（3） 。 保持器（3）具有两个平行的杆（10），每个平行的杆（10）上设有两排（11,12）叉形（13），排列成耙状，一排（11）的叉（13） 与所述杆（10）的第二排（12）形成锐角的杆（10）相对于所述两列（11,12）相对于彼此以“V”形配置，当 从横截面看。 一个杆（10）的尖头（13）的自由端指向另一个杆（10）的叉（13）的自由端。 两个杆（10）从共同的托架（14）延伸，共同的托架（14）保持和连接它们，其上设有托架（10）延伸用于板（2）的端面挡块（15）的端部 ），其具有朝向杆（10）彼此以钝角延伸的两个支腿（15a，15b），使得被支撑的矩形板仅由朝向该止挡件（15）的角部抵接（图1） 。

公开(公告)号：US4452532A

公开(公告)日：1984-06-05

申请号：US160625

申请日：1980-06-18

申请人： Everett C. Grollimund ,  Peter Martin

发明人： Everett C. Grollimund ,  Peter Martin

IPC分类号： G01B11/27 ,  G01B11/26

CPC分类号： G01B11/27

摘要： A method and apparatus for adjusting the alignment of a beam of radiant energy relative to a structure. A target is placed in the path of the beam, with an opaque reticle disposed in front of the target in the path of the beam in predetermined alignment with the structure. The beam impinges on the target to form a beam image and the reticle casts a shadow within the beam image. The positional relationship between the shadow and the outline of the beam image will be altered by any misalignment between the beam and the structure. The target is preferably chosen so that it will be permanently altered by the radiant energy of the beam, and the positional relationship between the shadow and the outline is preferably observed after exposure of the target to the beam.

摘要翻译： 一种用于调节相对于结构的辐射能束对准的方法和装置。 目标放置在光束的路径中，其中不透明的掩模版布置在与结构预定对准的光束路径中的目标前方。 光束撞击目标以形成光束图像，并且光罩在光束图像内投射阴影。 阴影和光束图像的轮廓之间的位置关系将被束和结构之间的任何未对准而改变。 目标优选地被选择为使得其将被束的辐射能永久地改变，并且优选地在目标暴露于光束之后观察阴影和轮廓之间的位置关系。

公开(公告)号：US11607080B2

公开(公告)日：2023-03-21

申请号：US17077664

申请日：2020-10-22

申请人： Peter Martin

发明人： Peter Martin

IPC分类号： A47J43/00 ,  A47J43/07 ,  A47J43/046 ,  A47G19/12

摘要： A beverage container for a blender includes one or more vibrating mechanisms coupled to a bottom portion of the beverage container or integrated within one or more walls of the beverage container. After a beverage has been blended, the one or more vibrating mechanisms are activated as the beverage is being poured. Vibrations from the one or more vibrating mechanisms are mechanically transmitted to the beverage container, thereby promoting the pourability of the beverage from the beverage container, including dislodging ingredients in the beverage that became lodged or trapped in crevices of the beverage container during the prior blending process, and freeing up beverage ingredients that accumulated at the bottom of the beverage container during the prior blending process.